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AMPK: a target for drugs and natural products with effects on both diabetes and cancer
Hardie, D. G., Jul 2013, In: Diabetes. 62, 7, p. 2164-2172 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile264 Citations (Scopus)137 Downloads (Pure) -
AMPK: regulating energy balance at the cellular and whole body levels
Hardie, D. G. & Ashford, M. L. J., Mar 2014, In: Physiology. 29, 2, p. 99-107 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile162 Citations (Scopus)165 Downloads (Pure) -
AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1-Parkin independent manner
Seabright, A. P., Fine, N. H. F., Barlow, J. P., Lord, S. O., Musa, I., Gray, A., Bryant, J. A., Banzhaf, M., Lavery, G. G., Hardie, D. G., Hodson, D. J., Philp, A. & Lai, Y-C., 4 May 2020, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 5, p. 6284-6301 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)81 Downloads (Pure) -
AMPK activators inhibit the proliferation of human melanomas bearing the activated MAPK pathway
Petti, C., Vegetti, C., Molla, A., Bersani, I., Cleris, L., Mustard, K. J., Formelli, F., Hardie, G. D., Sensi, M. & Anichini, A., 2012, In: Melanoma Research. 22, 5, p. 341-350 10 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B
Johanns, M., Lai, Y. C., Hsu, M. F., Jacobs, R., Vertommen, D., Van Sande, J., Dumont, J. E., Woods, A., Carling, D., Hue, L., Viollet, B., Foretz, M. & Rider, M. H., 8 Mar 2016, In: Nature Communications. 7, 10856.Research output: Contribution to journal › Article › peer-review
Open Access56 Citations (Scopus) -
AMPK Causes Cell Cycle Arrest in LKB1-deficient Cells via Activation of CAMKK2
Fogarty, S., Ross, F. A., Vara Ciruelos, D., Gray, A., Gowans, G. J. & Hardie, D. G., 1 Aug 2016, In: Molecular Cancer Research. 14, 8, p. 683-695 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Citations (Scopus)317 Downloads (Pure) -
AMPK dilates resistance arteries via activation of SERCA and BKCa channels in smooth muscle
Schneider, H., Schubert, K. M., Blodow, S., Kreutz, C-P., Erdogmus, S., Wiedenmann, M., Qiu, J., Fey, T., Ruth, P., Lubomirov, L. T., Pfitzer, G., Mederos y Schnitzler, M., Hardie, D. G., Gudermann, T. & Pohl, U., Jul 2015, In: Hypertension. 66, 1, p. 108-116 9 p.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus) -
AMPK modulates glucose-sensing in insulin-secreting cells by altered phosphotransfer to KATP channels
Beall, C., Watterson, K. R., McCrimmon, R. J. & Ashford, M. L. J., Jun 2013, In: Journal of Bioenergetics and Biomembranes. 45, 3, p. 229-241 13 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
AMPK promotes p53 acetylation via phosphorylation and inactivation of SIRT1 in liver cancer cells
Lee, C-W., Wong, L. L-Y., Tse, E. Y-T., Liu, H-F., Leong, V. Y-L., Lee, J. M-F., Hardie, D. G., Ng, I. O-L. & Ching, Y-P., 2012, In: Cancer Research. 72, 17, p. 4394-4404 11 p.Research output: Contribution to journal › Article › peer-review
132 Citations (Scopus) -
AMPK-sensing energy while talking to other signaling pathways
Hardie, D. G., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 939-952 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile317 Citations (Scopus)159 Downloads (Pure) -
AMPKα1: a glucose sensor that controls CD8 T-cell memory
Rolf, J., Zarrouk, M., Finlay, D. K., Foretz, M., Viollet, B. & Cantrell, D. A., Apr 2013, In: European Journal of Immunology. 43, 4, p. 889-896 8 p.Research output: Contribution to journal › Article › peer-review
138 Citations (Scopus) -
Amputation-free survival in 17,353 people at high risk for foot ulceration in diabetes: a national observational study
Scottish Diabetes Research Network Epidemiology Group, Vadiveloo, T., Jeffcoate, W., Donnan, P. T., Colhoun, H. C., McGurnaghan, S., Wild, S., McCrimmon, R. & Leese, G. P., Dec 2018, In: Diabetologia. 61, 12, p. 2590-2597 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)193 Downloads (Pure) -
A Multicellular Model of Intestinal Crypt Buckling and Fission
Almet, A. A., Hughes, B. D., Landman, K. A., Näthke, I. S. & Osborne, J. M., Feb 2018, In: Bulletin of Mathematical Biology. 80, 2, p. 335-359 25 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)228 Downloads (Pure) -
A multi-centre, parallel group superiority trial of silk therapeutic clothing compared to standard care for the management of eczema in children (CLOTHES Trial): study protocol for a randomised controlled trial
Harrison, E. F., Haines, R. H., Cowdell, F., Sach, T. H., Dean, T., Pollock, I., Burrows, N. P., Buckley, H., Batchelor, J., Williams, H. C., Lawton, S., Brown, S. J., Bradshaw, L. E., Ahmed, A., Montgomery, A. A., Mitchell, E. J. & Thomas, K. S., 2 Sep 2015, In: Trials. 16, 12 p., 390.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)173 Downloads (Pure) -
A multi-centre, prospective epidemiological surveillance study considering ophthalmic complications of functional endoscopic sinus surgery
Burgess, S., Foulds, J., White, P., Foot, B. & Macewen, C., Mar 2020, In: Journal of Laryngology and Otology. 134, 3, p. 228-232 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)43 Downloads (Pure) -
A Multi-disciplinary Approach to the Archaeological Investigation of a Bedrock-Dominated Shallow-Marine Landscape: An example from the Bay of Firth, Orkney, UK
Bates, M. R., Nayling, N., Bates, R., Dawson, S., Huws, D. & Wickham-Jones, C., Mar 2013, In: International Journal of Nautical Archaeology. 42, 1, p. 24-43 20 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
A multidisciplinary intervention to reduce antibiotic duration in lower respiratory tract infections
Murray, C., Shaw, A., Lloyd, M., Smith, R. P., Fardon, T. C., Schembri, S. & Chalmers, J. D., Feb 2014, In: Journal of Antimicrobial Chemotherapy. 69, 2, p. 515-518 4 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13
Leslie, E. J., Carlson, J. C., Shaffer, J. R., Feingold, E., Wehby, G., Laurie, C. A., Jain, D., Laurie, C. C., Doheny, K. F., McHenry, T., Resick, J., Sanchez, C., Jacobs, J., Emanuele, B., Vieira, A. R., Neiswanger, K., Lidral, A. C., Valencia-Ramirez, L. C., Lopez-Palacio, A. M., Valencia, D. R. & 35 others, , 1 Jul 2016, In: Human Molecular Genetics. 25, 13, p. 2862-2872 11 p.Research output: Contribution to journal › Article › peer-review
86 Citations (Scopus) -
A multifaceted approach to identify non-specific enzyme inhibition: Application to Mycobacterium tuberculosis shikimate kinase
Alturki, M. S., Fuanta, N. R., Jarrard, M. A., Hobrath, J. V., Goodwin, D. C., Rants'o, T. A. & Calderón, A. I., 15 Feb 2018, In: Bioorganic and Medicinal Chemistry Letters. 28, 4, p. 802-808 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)160 Downloads (Pure) -
A multifaceted intervention to improve sepsis management in general hospital wards with evaluation using segmented regression of interrupted time series
Marwick, C. A., Guthrie, B., Pringle, J. E. C., Evans, J. M. M., Nathwani, D., Donnan, P. T. & Davey, P. G., Dec 2014, In: BMJ Quality & Safety. 23, 12, 8 p., e2.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
A multiorganism pipeline for antiseizure drug discovery: Identification of chlorothymol as a novel γ-aminobutyric acidergic anticonvulsant
Jones, A., Barker-Haliski, M., Ilie, A. S., Herd, M. B., Baxendale, S., Holdsworth, C. J., Ashton, J. P., Placzek, M., Jayasekera, B. A. P., Cowie, C. J. A., Lambert, J. J., Trevelyan, A. J., White, H. S., Marson, A. G., Cunliffe, V. T., Sills, G. J. & Morgan, A., Oct 2020, In: Epilepsia. 61, 10, p. 2106-2118 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
A multiscale approach to curvature modulated sorting in biological membranes
Mercker, M., Ptashnyk, M., Kuhnle, J., Hartmann, D., Weiss, M. & Jager, W., May 2012, In: Journal of Theoretical Biology. 301, 5, p. 67-82 16 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
A multiscale mathematical model of tumour invasive growth
Peng, L., Trucu, D., Lin, P., Thompson, A. & Chaplain, M. A. J., Mar 2017, In: Bulletin of Mathematical Biology. 79, 3, p. 389-429 41 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)177 Downloads (Pure) -
A multiscale moving boundary model arising in cancer invasion
Trucu, D., Lin, P., Chaplain, M. A. J. & Wang, Y., 2013, In: Multiscale Modeling and Simulation: A SIAM Interdisciplinary Journal. 11, 1, p. 309-335 27 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
A multispecialty study of determining the possibility of pregnancy and the documentation of pregnancy status in surgical patients: a cause for concern?
Ibrahim, I., Ibrahim, B., Yong, G. L., Coats, M., Vujovic, Z. & Wilson, M. S. J., 1 Nov 2018, In: Scottish Medical Journal. 63, 4, p. 108-112 5 p.Research output: Contribution to journal › Article › peer-review
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A mutant O-GlcNAcase as a probe to reveal global dynamics of protein O-GlcNAcylation during Drosophila embryonic development
Mariappa, D., Selvan, N., Borodkin, V. S., Alonso, J., Ferenbach, A. T., Shepherd, C., Navratilova, I. H. & Van Aalten, D. M. F., Sep 2015, In: Biochemical Journal. 470, 2, p. 255-262 8 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
A mutant O-GlcNAcase enriches Drosophila developmental regulators
Selvan, N., Williamson, R., Mariappa, D., Campbell, D. G., Gourlay, R., Ferenbach, A. T., Aristotelous, T., Hopkins-Navratilova, I., Trost, M. & van Aalten, D. M. F., Aug 2017, In: Nature Chemical Biology. 13, 8, p. 882-887 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)199 Downloads (Pure) -
A mutual health service in Scotland: Do we understand fully the leadership implications?
Howieson, B. & Fenwick, C., Jul 2014, In: Leadership in Health Services. 27, 3, p. 193-203 11 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Amyloid β fibril disruption by oleuropein aglycone: long-time molecular dynamics simulation to gain insight into the mechanism of action of this polyphenol from extra virgin olive oil
Brogi, S., Sirous, H., Calderone, V. & Chemi, G., 23 Sep 2020, In: Food & Function. 11, 9, p. 8122-8132 11 p.Research output: Contribution to journal › Article › peer-review
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Anabolic resistance does not explain sarcopenia in patients with type 2 diabetes mellitus, compared with healthy controls, despite reduced mTOR pathway activity
Cuthbertson, D. J., Babraj, J., Leese, G. & Siervo, M., Dec 2017, In: Clinical Nutrition. 36, 6, p. 1716-1719 4 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
An accuracy assessment of forensic computerized facial reconstruction employing cone-beam computed tomography from live subjects
Lee, W-J., Wilkinson, C. M. & Hwang, H-S., Mar 2012, In: Journal of Forensic Sciences. 57, 2, p. 318-327 10 p.Research output: Contribution to journal › Article › peer-review
53 Citations (Scopus) -
An active DNA-based nanoprobe for photoacoustic pH imaging
Baumann, K. N., Fux, A. C., Joseph, J., Bohndiek, S. E. & Hernández-Ainsa, S., 2018, In: Chemical Communications. 54, 72, p. 10176-10178 3 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)8 Downloads (Pure) -
An acute transfusion reaction
Webb, C., Norris, A. & Hands, K., 1 Feb 2018, In: Clinical Medicine - Journal of the Royal College of Physicians of London. 18, 1, p. 95-97 3 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
An adaptive IEEE 802.15.4 MAC layer transmission scheme for applications with heterogeneous traffic
Zhou, Y., He, J., Chen, K., Tang, Z. & Li, Y., Dec 2013, In: Information: An Interdisciplinary Journal in English, Japanese and Chinese . 16, 12 A, p. 8451-8456 6 p.Research output: Contribution to journal › Article › peer-review
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An adaptive information technology for the operative diagnostics of the tropical cyclones: solar-terrestrial coupling mechanisms
Krapivin, V. F., Soldatov, V. Y., Varotsos, C. A. & Cracknell, A. P., 2012, In: Journal of Atmospheric and Solar-Terrestrial Physics. 89, p. 83-89 7 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
Anaesthesia for laryngo-tracheal surgery, including tubeless field techniques
Pearson, K. L. & McGuire, B. E., 1 Jul 2017, In: BJA Education. 17, 7, p. 242-248 7 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
An Affinity-directed PROtein Missile (AdPROM) system for targeted proteolysis
Fulcher, L., Macartney, T., Bozatzi, P., Hornberger, A., Rojas-Fernandez, A. & Sapkota, G., 26 Oct 2016, In: Open Biology. 6, 10, p. 1-9 9 p., 160255.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Citations (Scopus)173 Downloads (Pure) -
An African Legal Philosophy of Disability Justice: Between Discovery and Recognition
Onazi, O., 30 Jun 2016, In: ISRF Bulletin. Discovery & Recognition, X, p. 33-38 6 p.Research output: Contribution to journal › Article
Open AccessFile766 Downloads (Pure) -
An algorithm recommendation for the pharmacological management of allergic rhinitis in the UK: a consensus statement from an expert panel
Lipworth, B., Newton, J., Ram, B., Small, I. & Schwarze, J., 23 Jan 2017, In: NPJ Primary Care Respiratory Medicine. 27, p. 1-8 8 p., 3.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)173 Downloads (Pure) -
An alternate route to phosphorylating DegU of Bacillus subtilis using acetyl phosphate
Cairns, L. S., Martyn, J. E., Bromley, K. & Stanley-Wall, N. R., 31 Mar 2015, In: BMC Microbiology. 15, 12 p., 78.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
Analyses of groundwater flow and plant evapotranspiration in a vegetated soil slope
Leung, A. K. & Ng, C. W. W., Dec 2013, In: Canadian Geotechnical Journal. 50, 12, p. 1204-1218 15 p.Research output: Contribution to journal › Article › peer-review
44 Citations (Scopus) -
Analysis of a continuous finite element method for H(curl,div)-elliptic interface problem
Duan, H., Lin, P. & Tan, R. C. E., 2013, In: Numerische Mathematik. p. 1-37 37 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
Analysis of a model for banded vegetation patterns in semi-arid environments with nonlocal dispersal
Eigentler, L. & Sherratt, J. A., Sep 2018, In: Journal of Mathematical Biology. 77, 3, p. 739-763 25 p.Research output: Contribution to journal › Article › peer-review
11 Citations (Scopus) -
Analysis of barotactic and chemotactic guidance cues on directional decision-making of Dictyostelium discoideum cells in confined environments
Belotti, Y., McGloin, D. & Weijer, K., 13 Oct 2020, In: Proceedings of the National Academy of Sciences. 117, 41, p. 25553-25559 7 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Analysis of bender element test interpretation using the discrete element method
O’Donovan, J., O’Sullivan, C., Marketos, G. & Muir Wood, D., Apr 2015, In: Granular Matter. 17, 2, p. 197-216 20 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
Analysis of chain saw lubricating oils commonly used in Thailand's southern border provinces for forensic science purpose
Choodum, A., Tripuwanard, K. & Daeid, N. N., Aug 2014, In: Forensic Science International. 241, p. 60-68 9 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Analysis of consolidation with constant rate of displacement
Muir Wood, D., May 2016, In: Canadian Geotechnical Journal. 53, 5, p. 740-752 13 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Analysis of energy saving lamps for use by photosensitive individuals
Fenton, L., Ferguson, J. & Moseley, H., 2012, In: Photochemical & Photobiological Sciences. 11, 8, p. 1346-1355 10 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
Analysis of Global RNA Synthesis at the Single Cell Level following Hypoxia
Biddlestone, J., Druker, J., Shmakova, A., Ferguson, G., Swedlow, J. R. & Rocha, S., 13 May 2014, In: JoVE: Journal of Visualized Experiments. 87, 7 p., e51420.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)174 Downloads (Pure) -
Analysis of hand pressure in different crutch lengths and upper-limb movements during crutched walking
Sherif, S., Hasan, S., Arnold, G., Abboud, R. & Wang, W., May 2016, In: International Journal of Industrial Ergonomics. 53, p. 59-66 8 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus)