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  • Albena Dinkova-Kostova
2015
Open Access
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10 Citations (Scopus)
151 Downloads (Pure)

The emerging role of Nrf2 in mitochondrial function

Dinkova-Kostova, A. T. & Abramov, A. Y., Nov 2015, In : Free Radical Biology and Medicine. 88, Part B, p. 179-188 10 p.

Research output: Contribution to journalArticle

Open Access
File
314 Citations (Scopus)
267 Downloads (Pure)

The spatiotemporal regulation of the Keap1-Nrf2 pathway and its importance in cellular bioenergetics

Dinkova-Kostova, A. T., Baird, L., Holmström, K. M., Meyer, C. J. & Abramov, A. Y., Aug 2015, In : Biochemical Society Transactions. 43, 4, p. 602-610 9 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Transcription factors Hsf1 and Nrf2 engage in crosstalk for cytoprotection

Dayalan Naidu, S., Kostov, R. V. & Dinkova-Kostova, A. T., Jan 2015, In : Trends in Pharmacological Sciences. 36, 1, p. 6-14 9 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)
2014

Chemical tuning enhances both potency toward Nrf2 and in vitro therapeutic index of triterpenoids

Copple, I. M., Shelton, L. M., Walsh, J., Kratschmar, D. V., Lister, A., Odermatt, A., Goldring, C. E., Dinkova-Kostova, A. T., Honda, T. & Park, B. K., Aug 2014, In : Toxicological Sciences. 140, 2, p. 462-469 8 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
564 Downloads (Pure)

Monitoring Keap1-Nrf2 interactions in single live cells

Baird, L., Swift, S., Llères, D. & Dinkova-Kostova, A. T., 1 Nov 2014, In : Biotechnology Advances. 32, 6, p. 1133-1144 12 p.

Research output: Contribution to journalArticle

Open Access
File
82 Citations (Scopus)
352 Downloads (Pure)

Novel Thioureido Derivatives Carrying Thione and Sulfonamide Moieties Induce the Cytoprotective Enzyme NAD(P)H:Quione Oxidoreductase 1: Quinone oxidoreductase 1

Ghorab, M. M., Higgins, M., Dinkova-Kostova, A. T., Alsaid, M. S. & Shahat, A. A., 1 Dec 2014, In : Asian Journal of Chemistry. 26, 24, p. 8501-8504 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Nrf2 affects the efficiency of mitochondrial fatty acid oxidation

Ludtmann, M. H. R., Angelova, P. R., Zhang, Y., Abramov, A. Y. & Dinkova-Kostova, A. T., 1 Feb 2014, In : Biochemical Journal. 457, 3, p. 415-424 10 p.

Research output: Contribution to journalArticle

103 Citations (Scopus)

Sulphoxythiocarbamates modify cysteine residues in HSP90 causing degradation of client proteins and inhibition of cancer cell proliferation

Zhang, Y., Dayalan Naidu, S., Samarasinghe, K., Van Hecke, G. C., Pheely, A., Boronina, T. N., Cole, R. N., Benjamin, I. J., Cole, P. A., Ahn, Y-H. & Dinkova-Kostova, A. T., 7 Jan 2014, In : British Journal of Cancer. 110, 1, p. 71-82 12 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
99 Citations (Scopus)
278 Downloads (Pure)
7 Citations (Scopus)
810 Citations (Scopus)
2013

Chemoprotection Against Cancer by Isothiocyanates: A Focus on the Animal Models and the Protective Mechanisms

Dinkova-Kostova, A. T., 2013, Natural Products in Cancer Prevention and Therapy. Pezzuto, J. M. & Suh, N. (eds.). Berlin: Springer , p. 179-201 23 p. (Topics in Current Chemistry; vol. 329).

Research output: Chapter in Book/Report/Conference proceedingChapter

30 Citations (Scopus)

Diffusion dynamics of the Keap1-Cullin3 interaction in single live cells

Baird, L. & Dinkova-Kostova, A. T., 2013, In : Biochemical and Biophysical Research Communications. 433, 1, p. 58-65 8 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

NAD(P)H: Quinone oxidoreductase 1 inducer activity of some Saudi Arabian medicinal plants

Shahat, A. A., Alsaid, M. S., Alyahya, M. A., Higgins, M. & Dinkova-Kostova, A. T., Apr 2013, In : Planta Medica. 79, 6, p. 459-464 6 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration

Holmström, K. M., Baird, L., Zhang, Y., Hargreaves, I., Chalasani, A., Land, J. M., Stanyer, L., Yamamoto, M., Dinkova-Kostova, A. T. & Abramov, A. Y., 15 Aug 2013, In : Open Biology. 2, 8, p. 761-770 10 p.

Research output: Contribution to journalArticle

Open Access
File
186 Citations (Scopus)
203 Downloads (Pure)
163 Citations (Scopus)
4 Citations (Scopus)
2012

Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity

Calabrese, V., Cornelius, C., Dinkova-Kostova, A. T., Iavicoli, I., Di Paola, R., Koverech, A., Cuzzocrea, S., Rizzarelli, E. & Calabrese, E. J., May 2012, In : Biochimica et Biophysica Acta. Molecular Basis of Disease. 1822, 5, p. 753-783 31 p.

Research output: Contribution to journalReview article

255 Citations (Scopus)

Glucosinolates and isothiocyanates in health and disease

Dinkova-Kostova, A. T. & Kostov, R. V., 2012, In : Trends in Molecular Medicine. 18, 6, p. 337-347 11 p.

Research output: Contribution to journalArticle

313 Citations (Scopus)

Glutathione S-transferase genotype is associated with sensitivity to psoralen-ultraviolet A photochemotherapy

Ibbotson, S. H., Dawe, R. S., Dinkova-Kostova, A. T., Weidlich, S., Farr, P. M., Ferguson, J., Wolf, C. R. & Smith, G., Feb 2012, In : British Journal of Dermatology. 166, 2, p. 380-388 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
29 Citations (Scopus)

Neuroprotective effects of sulforaphane after contusive spinal cord injury

Benedict, A. L., Mountney, A., Hurtado, A., Bryan, K. E., Schnaar, R. L., Dinkova-Kostova, A. T. & Talalay, P., 2012, In : Journal of Neurotrauma. 29, 16, p. 2576-2586 11 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Synthesis, chemical reactivity as Michael acceptors, and biological potency of monocyclic cyanoenones, novel and highly potent anti-inflammatory and cytoprotective agents

Zheng, S., Laxmi, Y. R. S., David, E., Dinkova-Kostova, A. T., Shiavoni, K. H., Ren, Y., Zheng, Y., Trevino, I., Bumeister, R., Ojima, I., Wigley, W. C., Bliska, J. B., Mierke, D. F. & Honda, T., 24 May 2012, In : Journal of Medicinal Chemistry. 55, 10, p. 4837-4846 10 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

The indirect antioxidant sulforaphane protects against thiopurine-mediated photooxidative stress

Benedict, A. L., Knatko, E. V. & Dinkova-Kostova, A. T., Dec 2012, In : Carcinogenesis. 33, 12, p. 2457-2466 10 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)