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Author

  • Brian Lipworth
2012

Allergic Rhinitis and its Impact on Asthma (ARIA): Achievements in 10 years and future needs

Bousquet, J., Schünemann, H. J., Samolinski, B., Demoly, P., Baena-Cagnani, C. E., Bachert, C., Bonini, S., Boulet, L. P., Bousquet, P. J., Brozek, J. L., Canonica, G. W., Casale, T. B., Cruz, A. A., Fokkens, W. J., Fonseca, J. A., Van Wijk, R. G., Grouse, L., Haahtela, T., Khaltaev, N., Kuna, P. & 213 others, Lockey, R. F., Lodrup Carlsen, K. C., Mullol, J., Naclerio, R., O'hehir, R. E., Ohta, K., Palkonen, S., Papadopoulos, N. G., Passalacqua, G., Pawankar, R., Price, D., Ryan, D., Simons, F. E. R., Togias, A., Williams, D., Yorgancioglu, A., Yusuf, O. M., Aberer, W., Adachi, M., Agache, I., Aït-Khaled, N., Akdis, C. A., Andrianarisoa, A., Annesi-Maesano, I., Ansotegui, I. J., Baiardini, I., Bateman, E. D., Bedbrook, A., Beghé, B., Beji, M., Bel, E. H., Ben Kheder, A., Bennoor, K. S., Bergmann, K. C., Berrissoul, F., Bieber, T., Bindslev Jensen, C., Blaiss, M. S., Boner, A. L., Bouchard, J., Braido, F., Brightling, C. E., Bush, A., Caballero, F., Calderon, M. A., Calvo, M. A., Camargos, P. A. M., Caraballo, L. R., Carlsen, K. H., Carr, W., Cepeda, A. M., Cesario, A., Chavannes, N. H., Chen, Y. Z., Chiriac, A. M., Chivato Pérez, T., Chkhartishvili, E., Ciprandi, G., Costa, D. J., Cox, L., Custovic, A., Dahl, R., Darsow, U., De Blay, F., Deleanu, D., Denburg, J. A., Devillier, P., Didi, T., Dokic, D., Dolen, W. K., Douagui, H., Dubakiene, R., Durham, S. R., Dykewicz, M. S., El-Gamal, Y., El-Meziane, A., Emuzyte, R., Fiocchi, A., Fletcher, M., Fukuda, T., Gamkrelidze, A., Gereda, J. E., González Diaz, S., Gotua, M., Guzmán, M. A., Hellings, P. W., Hellquist-Dahl, B., Horak, F., Hourihane, JOB., Howarth, P., Humbert, M., Ivancevich, J. C., Jackson, C., Just, J., Kalayci, O., Kaliner, M. A., Kalyoncu, A. F., Keil, T., Keith, P. K., Khayat, G., Kim, Y. Y., Koffi N'Goran, B., Koppelman, G. H., Kowalski, M. L., Kull, I., Kvedariene, V., Larenas-Linnemann, D., Le, L. T., Lemière, C., Li, J., Lieberman, P., Lipworth, B., Mahboub, B., Makela, M. J., Martin, F., Marshall, G. D., Martinez, F. D., Masjedi, M. R., Maurer, M., Mavale-Manuel, S., Mazon, A., Melen, E., Meltzer, E. O., Mendez, N. H., Merk, H., Mihaltan, F., Mohammad, Y., Morais-Almeida, M., Muraro, A., Nafti, S., Namazova-Baranova, L., Nekam, K., Neou, A., Niggemann, B., Nizankowska-Mogilnicka, E., Nyembue, T. D., Okamoto, Y., Okubo, K., Orru, M. P., Ouedraogo, S., Ozdemir, C., Panzner, P., Pali-Schöll, I., Park, H. S., Pigearias, B., Pohl, W., Popov, T. A., Postma, D. S., Potter, P., Rabe, K. F., Ratomaharo, J., Reitamo, S., Ring, J., Roberts, R., Rogala, B., Romano, A., Roman Rodriguez, M., Rosado-Pinto, J., Rosenwasser, L., Rottem, M., Sanchez-Borges, M., Scadding, G. K., Schmid-Grendelmeier, P., Sheikh, A., Sisul, J. C., Solé, D., Sooronbaev, T., Spicak, V., Spranger, O., Stein, R. T., Stoloff, S. W., Sunyer, J., Kogevinas, M., Szczeklik, A., Todo-Bom, A., Toskala, E., Tremblay, Y., Valenta, R., Valero, A. L., Valeyre, D., Valiulis, A., Valovirta, E., Van Cauwenberge, P., Vandenplas, O., Van Weel, C., Vichyanond, P., Viegi, G., Wang, D. Y., Wickman, M., Wöhrl, S., Wright, J., Yawn, B. P., Yiallouros, P. K., Zar, H. J., Zernotti, M. E., Zhong, N., Zidarn, M., Zuberbier, T., Oddie, S., Baigenzhin, A. K., Boakye, D. A., Briggs, A. H., Burney, P. G., Busse, W. W., Chuchalin, A. G., Haddad, H., Johnston, S. L., Levy, M. L., Mohammadi, A., Rezagui, D., Terreehorst, I., Warner, J. O. & Ang, C. S., 2012, In : Journal of Allergy and Clinical Immunology. 130, 5, p. 1049-1062 14 p.

Research output: Contribution to journalArticle

347 Citations (Scopus)

A randomized primary care trial of steroid titration against mannitol in persistent asthma: STAMINA trial

Lipworth, B. J., Short, P. M., Williamson, P. A., Clearie, K. L., Fardon, T. C. & Jackson, C. M., 2012, In : Chest. 141, 3, p. 607-15 9 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Are we overlooking persistent small airways dysfunction in community-managed asthma?

Anderson, W. J., Zajda, E. & Lipworth, B. J., 2012, In : Annals of Allergy, Asthma & Immunology. 109, 3, p. 185-189 5 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Comparative evaluation of nasal blood flow and airflow in the decongestant response to oxymetazoline

Vaidyanathan, S., Williamson, P. & Lipworth, B., Feb 2012, In : Annals of Allergy, Asthma & Immunology. 108, 2, p. 77-80 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Does body mass index influence responsiveness to inhaled corticosteroids in persistent asthma?

Anderson, W. J. & Lipworth, B. J., Apr 2012, In : Annals of Allergy, Asthma & Immunology. 108, 4, p. 237-242 6 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Effects of Extra-Fine Inhaled and Oral Corticosteroids on Alveolar Nitric Oxide in COPD

Short, P. M., Williamson, P. A. & Lipworth, B. J., Aug 2012, In : Lung. 190, 4, p. 395-401 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Effects of hydrocortisone on acute β-adrenoceptor blocker and histamine induced bronchoconstriction

Short, P. M., Williamson, P. A. & Lipworth, B. J., May 2012, In : British Journal of Clinical Pharmacology. 73, 5, p. 717-726 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Effects of intranasal salmeterol and fluticasone given alone and in combination in persistent allergic rhinitis

Lipworth, B. J., Short, P., Burns, P. & Nair, A., Jan 2012, In : Annals of Allergy, Asthma & Immunology. 108, 1, p. 54-59 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Fluticasone/Salmeterol Combination Confers Benefits in People With Asthma Who Smoke

Clearie, K. L., McKinlay, L., Williamson, P. A. & Lipworth, B. J., Feb 2012, In : Chest. 141, 2, p. 330-338 9 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Inhaled corticosteroid dose response using domiciliary exhaled nitric oxide in persistent asthma: the FENOtype trial

Anderson, W. J., Short, P., Williamson, P. A. & Lipworth, B. J., Dec 2012, In : Chest. 142, 6, p. 1553-61 9 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Is a positive nasal lysine-aspirin challenge test associated with a more severe phenotype of chronic rhinosinusitis and asthma?

Vaidyanathan, S., Williamson, P. A. & Lipworth, B. J., 2012, In : American Journal of Rhinology & Allergy. 26, 3, p. E89-E93 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
8 Citations (Scopus)
14 Citations (Scopus)

Relationships between impulse oscillometry, spirometry and dyspnoea in COPD

Anderson, W. J. & Lipworth, B. J., 2012, In : Journal of the Royal College of Physicians of Edinburgh. 42, 2, p. 111-115 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
22 Citations (Scopus)

Severe chronic allergic (and related) diseases: a uniform approach - A MeDALL - GA(2)LEN - ARIA position paper

Bousquet, J., Anto, J. M., Demoly, P., Schuenemann, H. J., Togias, A., Akdis, M., Auffray, C., Bachert, C., Bieber, T., Bousquet, P. J., Carlsen, K. H., Casale, T. B., Cruz, A. A., Keil, T., Carlsen, K. C. L., Maurer, M., Ohta, K., Papadopoulos, N. G., Rodriguez, M. R., Samolinski, B. & 31 others, Agache, I., Andrianarisoa, A., Ang, C. S., Annesi-Maesano, I., Ballester, F., Baena-Cagnani, C. E., Basagana, X., Bateman, E. D., Bel, E. H., Bedbrook, A., Beghe, B., Beji, M., Ben Kheder, A., Benet, M., Bennoor, K. S., Bergmann, K. C., Berrissoul, F., Jensen, C. B., Bleecker, E. R., Bonini, S., Boner, A. L., Boulet, L. P., Brightling, C. E., Brozek, J. L., Bush, A., Busse, W. W., Camargos, P. A. M., Canonica, G. W., Carr, W., Lipworth, B. & WHO Collaborating Ctr Asthma, 2012, In : International Archives of Allergy and Immunology. 158, 3, p. 216-231 16 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

The impact of tiotropium on mortality and exacerbations when added to inhaled corticosteroids and long-acting β-agonist therapy in COPD

Short, P. M., Williamson, P. A., Elder, D. H. J., Lipworth, S. I. W., Schembri, S. & Lipworth, B. J., Jan 2012, In : Chest. 141, 1, p. 81-86 6 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Tiotropium in asthma

Lipworth, B., Manoharan, A. & Short, P., 27 Dec 2012, In : New England Journal of Medicine. 367, 26, p. 2552 1 p.

Research output: Contribution to journalLetter

3 Citations (Scopus)
2013

Adrenal suppression with fluticasone furoate

Lipworth, B. J., Mar 2013, In : Annals of Allergy, Asthma & Immunology. 110, 3, p. 213

Research output: Contribution to journalLetter

Adverse effects of long-acting Beta-agonists on airway hyperresponsiveness

Lipworth, B., Manoharan, A. & Short, P., Sep 2013, In : American Journal of Respiratory Cell and Molecular Biology. 49, 3, p. 501-502 2 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Author response

Lipworth, B., Sep 2013, In : Annals of Allergy, Asthma & Immunology. 111, 3, p. 234 1 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Explaining differential effects of tiotropium on mortality in COPD

Lipworth, B. J. & Short, P., 2013, In : Thorax. 68, 6, p. 589-590 2 p.

Research output: Contribution to journalLetter

3 Citations (Scopus)

Influence of β2-adrenergic receptor polymorphism on methacholine hyperresponsiveness in asthmatic patients

Manoharan, A., Anderson, W. J. & Lipworth, B. J., Mar 2013, In : Annals of Allergy, Asthma & Immunology. 110, 3, p. 161-164 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Inhaled and Systemic Corticosteroid Response in Severe Asthma Assessed by Alveolar Nitric Oxide: a randomised crossover pilot study of add-on therapy

Williamson, P. A., Short, P. M., Vaidyanathan, S. & Lipworth, B. J., Jan 2013, In : British Journal of Clinical Pharmacology. 75, 1, p. 93-102 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Left Ventricular Hypertrophy in COPD Without Hypoxemia: The Elephant in the Room?

Anderson, W. J., Lipworth, B. J., Rekhraj, S., Struthers, A. D. & George, J., Jan 2013, In : Chest. 143, 1, p. 91-97 7 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Randomised Placebo-controlled Trial to Evaluate Chronic Dosing Effects of Propranolol in Asthma

Short, P. M., Williamson, P. A., Anderson, W. J. & Lipworth, B. J., 15 Jun 2013, In : American Journal of Respiratory and Critical Care Medicine. 187, 12, p. 1308-1314 7 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Relationship of large and small airway response with inhaled corticosteroid to asthma control

Manoharan, A., Anderson, W. J. & Lipworth, B. J., Aug 2013, In : Annals of Allergy, Asthma & Immunology. 111, 2, p. 140-142 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Systemic safety of fluticasone furoate/vilanterol combination

Lipworth, B., Dec 2013, In : Thorax. 68, 12, p. 1165

Research output: Contribution to journalLetter

2 Citations (Scopus)

Tailored second-line therapy in asthmatic children with the Arg16 genotype

Lipworth, B. J., Basu, K., Donald, H. P., Tavendale, R., MacGregor, D. F., Ogston, S. A., Palmer, C. N. A. & Mukhopadhyay, S., Apr 2013, In : Clinical Science. 124, 8, p. 521-528 8 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Targeting the small airways asthma phenotype: if we can reach it, should we treat it?

Lipworth, B., Apr 2013, In : Annals of Allergy, Asthma & Immunology. 110, 4, p. 233-239 7 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
1 Citation (Scopus)
7 Citations (Scopus)
2014

Adrenal suppression with mometasone furoate/formoterol

Lipworth, B. J., May 2014, In : Chest. 145, 5, p. 1175-1176 2 p.

Research output: Contribution to journalLetter

49 Citations (Scopus)

Effects of intravenous and oral β-blockade in persistent asthmatics controlled on inhaled corticosteroids

Short, P. M., Anderson, W. J., Williamson, P. A. & Lipworth, B. J., Feb 2014, In : Heart (British Cardiac Society). 100, 3, p. 219-223 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Emerging role of long acting muscarinic antagonists for asthma

Lipworth, B. J., Jan 2014, In : British Journal of Clinical Pharmacology. 77, 1, p. 55-62 8 p.

Research output: Contribution to journalReview article

23 Citations (Scopus)

Impact of long-acting bronchodilators and exposure to inhaled corticosteroids on mortality in COPD: a real-life retrospective cohort study

Manoharan, A., Short, P. M., Anderson, W. J. & Lipworth, B. J., Oct 2014, In : Lung. 192, 5, p. 649-652 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Influence of β2-adrenoceptor 16 genotype on propranolol-induced bronchoconstriction in patients with persistent asthma

Anderson, W. J., Short, P. M., Manoharan, A., Lipworth, J. L. R. & Lipworth, B. J., 2014, In : Annals of Allergy, Asthma & Immunology. 112, 5, p. 475-476 2 p.

Research output: Contribution to journalLetter

4 Citations (Scopus)

Proof of concept evaluation of trough airway hyper-responsiveness following regular racemic or levosalbutamol in genotype-stratified steroid-treated persistent asthmatic patients

Anderson, W. J., Short, P. M., Williamson, P. A., Morrison, A. E., Palmer, C., Tavendale, R. & Lipworth, B. J., 1 Jan 2014, In : Clinical Science. 126, 1, p. 75-83 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Reply: pharmacological obfuscation of clinical relevance

Lipworth, B., Short, P., Anderson, W. & Williamson, P., 1 Feb 2014, In : American Journal of Respiratory and Critical Care Medicine. 189, 3, p. 360-361 2 p.

Research output: Contribution to journalLetter

2 Citations (Scopus)
41 Citations (Scopus)

Small airway dysfunction is associated with poorer asthma control

Manoharan, A., Anderson, W. J., Lipworth, J., Ibrahim, I. & Lipworth, B. J., Nov 2014, In : European Respiratory Journal. 44, 5, p. 1353-1355 3 p.

Research output: Contribution to journalArticle

Open Access
File
29 Citations (Scopus)
118 Downloads (Pure)

Tadalafil in patients with chronic obstructive pulmonary disease: a randomised, double-blind, parallel-group, placebo-controlled trial

Goudie, A. R., Lipworth, B. J., Hopkinson, P. J., Wei, L. & Struthers, A. D., Apr 2014, In : The Lancet Respiratory Medicine. 2, 4, p. 293-300 8 p.

Research output: Contribution to journalArticle

Open Access
File
53 Citations (Scopus)
151 Downloads (Pure)

The inverse agonist propranolol confers no corticosteroid-sparing activity in mild-to-moderate persistent asthma

Anderson, W. J., Short, P. M., Williamson, P. A., Manoharan, A. & Lipworth, B. J., Dec 2014, In : Clinical Science. 127, 11, p. 635-643 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

The potential role of direct and indirect bronchial challenge testing to identify overtreatment of community managed asthma

Manoharan, A., Lipworth, B., Craig, E. & Jackson, C., Oct 2014, In : Clinical and Experimental Allergy. 44, 10, p. 1240-1245 6 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Unlocking the quiet zone: the small airway asthma phenotype

Lipworth, B., Manoharan, A. & Anderson, W., 2014, In : The Lancet Respiratory Medicine. 2, 6, p. 497-506 10 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)
2015

Assessment of spirometry and impulse oscillometry in relation to asthma control

Manoharan, A., Anderson, W. J., Lipworth, J. & Lipworth, B. J., Feb 2015, In : Lung. 193, 1, p. 47-51 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Biomarkers to predict inhaled corticosteroid response

Lipworth, B. J., Aug 2015, In : Journal of Allergy and Clinical Immunology. 136, 2, p. 515 1 p.

Research output: Contribution to journalLetter

2 Citations (Scopus)