Find Research Outputs

Search results

• A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway is Associated with Major Depressive Disorder

  Zeng, Y., Navarro, P., Fernandez-Pujals, A. M., Hall, L. S., Clarke, T-K., Thomson, P. A., Smith, B. H., Hocking, L. J., Padmanabhan, S., Hayward, C., MacIntyre, D. J., Wray, N. R., Deary, I. J., Porteous, D. J., Haley, C. S., McIntosh, A. M. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 15 Feb 2017, In: Biological Psychiatry. 81, 4, p. 336-346 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Major Depressive Disorder
  • Genome-Wide Association Study
  • Area Under Curve
  • Linear Models
  • Multilevel Analysis
  18 Citations (Scopus)

  407 Downloads (Pure)

• Alzheimer's disease risk factor complement receptor 1 is associated with depression

  Hamilton, G., Evans, K. L., MacIntyre, D. J., Deary, I. J., Dominiczak, A., Smith, B. H., Morris, A. D., Porteous, D. J. & Thomson, P. A., 2012, In: Neuroscience Letters. 510, 1, p. 6-9 4 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Ask the experts: neuropathic pain from a primary care perspective

  Smith, B. H., May 2013, In: Pain Management. 3, 3, p. 173-6 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Scotland
  • Neuralgia
  • Primary Health Care
  • General Practitioners
  • Chronic Pain

• Assessing the presence of shared genetic architecture between Alzheimer's disease and major depressive disorder using genome-wide association data

  Gibson, J., Russ, T. C., Adams, M. J., Clarke, T-K., Howard, D. M., Hall, L. S., Fernandez-Pujals, A. M., Wigmore, E. M., Hayward, C., Davies, G., Murray, A. D., Smith, B. H., Porteous, D. J., Deary, I. J. & McIntosh, A. M., 18 Apr 2017, In: Translational Psychiatry. 7, p. 1-8 8 p., e1094.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Major Depressive Disorder
  • Alzheimer Disease
  • Genome
  • Depression
  • Genomics
  15 Citations (Scopus)

  196 Downloads (Pure)

• Association of DISC1 variants with age of onset in a population-based sample of recurrent major depression

  Thomson, P. A., MacIntyre, D. J., Hamilton, G., Dominiczak, A., Smith, B. H., Morris, A., Evans, K. L. & Porteous, D. J., Jul 2013, In: Molecular Psychiatry. 18, 7, p. 745-747 3 p.

  Research output: Contribution to journal › Letter › peer-review
  9 Citations (Scopus)

• A study of National Health Service management of chronic osteoarthritis and low back pain

  Hart, O. R., Uden, R. M., McMullan, J. E., Ritchie, M. S., Williams, T. D. & Smith, B. H., 2014, In: Primary Health Care Research and Development. 16, 2, p. 157-166 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • National Health Programs
  • Low Back Pain
  • Osteoarthritis
  • Chronic Pain
  • Primary Health Care
  4 Citations (Scopus)

  180 Downloads (Pure)

• Can pragmatic trials help us better understand chronic pain and improve treatment?

  Rowbotham, M. C., Gilron, I., Glazer, C., Rice, A. S. C., Smith, B. H., Stewart, W. F. & Wasan, A. D., May 2013, In: Pain. 154, 5, p. 643-646 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Pragmatic Clinical Trials
  • Chronic Pain
  • Population Health
  • Global Health
  • Comorbidity
  27 Citations (Scopus)

• Cardiovascular risk factors associated with the metabolic syndrome are more prevalent in people reporting chronic pain: results from a cross-sectional general population study

  Goodson, N. J., Smith, B. H., Hocking, L. J., McGilchrist, M. M., Dominiczak, A. F., Morris, A., Porteous, D. J. & Goebel, A., Sep 2013, In: Pain. 154, 9, p. 1595-1602 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Metabolic Syndrome
  • Chronic Pain
  • Population
  • Coronary Disease
  • Pain
  39 Citations (Scopus)

• Chronic pain, depression and cardiovascular disease linked through a shared genetic predisposition: Analysis of a family-based cohort and twin study

  van Hecke, O., Hocking, L. J., Torrance, N., Campbell, A., Padmanabhan, S., Porteous, D. J., McIntosh, A. M., Burri, A. V., Tanaka, H., Williams, F. M. K. & Smith, B. H., 22 Feb 2017, In: PLoS ONE. 12, 2, 19 p., e0170653.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • cohort studies
  • Twin Studies
  • cardiovascular diseases
  • pain
  • Genetic Predisposition to Disease
  20 Citations (Scopus)

  188 Downloads (Pure)

• Chronic pain epidemiology and its clinical relevance

  van Hecke, O., Torrance, N. & Smith, B. H., 2013, In: British Journal of Anaesthesia. 111, 1, p. 13-18 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Chronic Pain
  • Epidemiology
  • Biological Factors
  • Epidemiologic Studies
  • Population
  236 Citations (Scopus)

• Cohort profile: Generation Scotland: Scottish Family Health Study (GS:SFHS). The study, its participants and their potential for genetic research on health and illness

  Smith, B. H., Campbell, A., Linksted, P., Fitzpatrick, B., Jackson, C., Kerr, S. M., Deary, I. J., Macintyre, D. J., Campbell, H., McGilchrist, M., Hocking, L. J., Wisely, L., Ford, I., Lindsay, R. S., Morton, R., Palmer, C. N. A., Dominiczak, A. F., Porteous, D. J. & Morris, A. D., Jun 2013, In: International Journal of Epidemiology. 42, 3, p. 689-700 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Genetic Research
  • Family Health
  • Scotland
  • Health
  • Comprehensive Health Care
  133 Citations (Scopus)

• Cohort profile: The Scottish Research Register SHARE: A register of people interested in research participation linked to NHS datasets

  McKinstry, B., Sullivan, F. M., Vasishta, S., Armstrong, R., Hanley, J., Haughney, J., Philip, S., Smith, B. H., Wood, A. & Palmer, C. N. A., 1 Feb 2017, In: BMJ Open. 7, 2, p. 1-8 8 p., e013351.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Datasets
  • Scotland
  • Mobile Applications
  • Phlebotomy
  • Patient Participation
  12 Citations (Scopus)

  177 Downloads (Pure)

• Commentary: a thesis that still warrants defence and promotion

  Smith, B. H., Guthrie, B., Sullivan, F. M. & Morris, A. D., 2012, In: International Journal of Epidemiology. 41, 6, p. 1518-1522 5 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

  Rietveld, C. A., Esko, T., Davies, G., Pers, T. H., Turley, P., Benyamin, B., Chabris, C. F., Emilsson, V., Johnson, A. D., Lee, J. J., Leeuw, C. D., Marioni, R. E., Medland, S. E., Miller, M. B., Rostapshova, O., van der Lee, S. J., Vinkhuyzen, A. A. E., Amin, N., Conley, D., Derringer, J. & 39 others, van Duijn, C. M., Fehrmann, R., Franke, L., Glaeser, E. L., Hansell, N. K., Hayward, C., Iacono, W. G., Ibrahim-Verbaas, C., Jaddoe, V., Karjalainen, J., Laibson, D., Lichtenstein, P., Liewald, D. C., Magnusson, P. K. E., Martin, N. G., McGue, M., McMahon, G., Pedersen, N. L., Pinker, S., Porteous, D. J., Posthuma, D., Rivadeneira, F., Smith, B. H., Starr, J. M., Tiemeier, H., Timpson, N. J., Trzaskowski, M., Uitterlinden, A. G., Verhulst, F. C., Ward, M. E., Wright, M. J., Davey Smith, G., Deary, I. J., Johannesson, M., Plomin, R., Visscher, P. M., Benjamin, D. J., Cesarini, D. & Koellinger, P. D., 23 Sep 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 38, p. 13790-13794 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Proxy
  • Single Nucleotide Polymorphism
  • Phenotype
  • Education
  • Memory
  133 Citations (Scopus)

• Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

  Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D. & 31 others, Hayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P. M., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, J. M., Kleber, M. E., Hollensted, M., Lohman, K., Rivera, N. V., Whitfield, J. B., Zhao, J. H., Stringham, H. M., Lyytikäinen, L-P., Huppertz, C., Willemsen, G., Smith, B. H. & CHARGE Consortium, Aug 2017, In: PLoS Genetics. 13, 8, p. e1006972 1 p.

  Research output: Contribution to journal › Article › peer-review

  • adiposity
  • physical activity
  • meta-analysis
  • Adiposity
  • genome
  2 Citations (Scopus)

• Corrigendum to "Neuropathic pain in the general population:a systematic review of epidemiological studies": [PAIN® 155(4) pp. 654-662 (2014)] (DOI:10.1016/j.pain.2013.11.013)

  van Hecke, O., Austin, S. K., Khan, R. A., Smith, B. H. & Torrance, N., Sep 2014, In: Pain. 155, 9, p. 1907 1 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Cost-effectiveness of self-management methods for the treatment of chronic pain in an aging adult population: a systematic review of the literature

  Boyers, D., McNamee, P., Clarke, A., Jones, D., Martin, D., Schofield, P. & Smith, B. H., Apr 2013, In: Clinical Journal of Pain. 29, 4, p. 366-375 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Self-Management
  • Chronic Pain
  • Cost-Benefit Analysis
  • Systematic Reviews
  • Quality-Adjusted Life Years
  25 Citations (Scopus)

• Does a history of depression actually mediate smoking-related pain? findings from a cross-sectional general population-based study

  van Hecke, O., Torrance, N., Cochrane, L., Cavanagh, J., Donnan, P. T., Padmanabhan, S., Porteous, D. J., Hocking, L. & Smith, B. H., Oct 2014, In: European Journal of Pain. 18, 9, p. 1223-1230 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Smoking
  • Depression
  • Pain
  • Population
  • Smokers
  5 Citations (Scopus)

• Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n=19,762), UK Biobank (n=24,048) and the English Longitudinal Study of Ageing (n=5,766)

  Wigmore, E. M., Clarke, T-K., Howard, D. M., Adams, M. J., Hall, L. S., Zeng, Y., Gibson, J., Davies, G., Fernandez-Pujals, A. M., Thomson, P. A., Hayward, C., Smith, B. H., Hocking, L. J., Padmanabhan, S., Deary, I. J., Porteous, D., Nicodemus, K. K. & McIntosh, A. M., 15 Aug 2017, In: Translational Psychiatry. 7, 9 p., e1205.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Scotland
  • Major Depressive Disorder
  • Longitudinal Studies
  • Brain
  • Family Health
  12 Citations (Scopus)

  183 Downloads (Pure)

• Editorial IV. Managing chronic pain: a clinical challenge: new SIGN guidelines provide a practical evidence-based approach and identify research gaps

  Colvin, L. A., Stein, A. & Smith, B. H., 2014, In: BRITISH JOURNAL OF ANAESTHESIA. 112, 1, p. 9-12 4 p.

  Research output: Contribution to journal › Editorial › peer-review
  2 Citations (Scopus)

• eHealth and the use of individually tailored information: a systematic review

  Conway, N., Webster, C., Smith, B. & Wake, D., Sep 2017, In: Health Informatics Journal. 23, 3, p. 201-233 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Telemedicine
  • Systematic Reviews
  • Clinical Studies
  • Controlled Clinical Trials
  • Disease Management
  7 Citations (Scopus)

  21 Downloads (Pure)

• Epidemiology of neuropathic pain and its impact on quality of life

  Smith, B. H. & Torrance, N., 1 Jun 2012, In: Current Pain and Headache Reports. 16, 3, p. 191-198 8 p.

  Research output: Contribution to journal › Article › peer-review
  133 Citations (Scopus)

• Erratum: Neuropathic pain: a pathway for care developed by the British Pain Society

  Smith, B. H., Lee, J., Price, C. & Baranowski, A. P., Sep 2013, In: BRITISH JOURNAL OF ANAESTHESIA. 111, 3, p. 522 1 p.

  Research output: Contribution to journal › Article › peer-review

• Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

  Christophersen, I. E., Rienstra, M., Roselli, C., Yin, X., Geelhoed, B., Barnard, J., Lin, H., Arking, D. E., Smith, A. V., Albert, C. M., Chaffin, M., Tucker, N. R., Li, M., Klarin, D., Bihlmeyer, N. A., Low, S-K., Weeke, P. E., Müller-Nurasyid, M., Smith, J. G., Brody, J. A. & 31 others, Niemeijer, M. N., Dörr, M., Trompet, S., Huffman, J., Gustafsson, S., Schurmann, C., Kleber, M. E., Lyytikäinen, L-P., Seppälä, I., Malik, R., R V R Horimoto, A., Perez, M., Sinisalo, J., Aeschbacher, S., Thériault, S., Yao, J., Radmanesh, F., Weiss, S., Teumer, A., Choi, S. H., Weng, L-C., Clauss, S., Deo, R., Rader, D. J., Shah, S. H., Sun, A., Hopewell, J. C., Debette, S., Smith, B. H., Morris, A. P. & METASTROKE Consortium of the ISGC, Neurology Working Group of the CHARGE Consortium, 27 Jul 2017, In: Nature Genetics. 49, 8, p. 1286 1 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Estimating the burden of disease in chronic pain with and without neuropathic characteristics: does the choice between the EQ-5D and SF-6D matter?

  Torrance, N., Lawson, K. D., Afolabi, E., Bennett, M. I., Serpell, M. G., Dunn, K. M. & Smith, B. H., Oct 2014, In: Pain. 155, 10, p. 1996-2004 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Chronic Pain
  • Health
  • Pain
  • Quality of Life
  • Mental Health
  35 Citations (Scopus)

  264 Downloads (Pure)

• Exome-wide association study of plasma lipids in >300,000 individuals

  Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X-Y., Mahajan, A., Saleheen, D., Emdin, C., Alam, D. S., Alves, A. C., Amouyel, P., Di Angelantonio, E., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C. & 33 others, Boehnke, M., Boerwinkle, E., Bork-Jensen, J., Bottinger, E. P., Brandslund, I., Brown, M. J., Busonero, F., Caulfield, M. J., Chambers, J. C., Chasman, D. I., Chen, Y. E., Chen, Y-D. I., Chowdhury, R., Christensen, C., Chu, A. Y., Connell, J. M., Cucca, F., Cupples, L. A., Damrauer, S. M., Davies, G., Deary, I. J., Dedoussis, G., Denny, J. C., Dominiczak, A. F., Dubé, M. P., Ebeling, T., Eiriksdottir, G., Esko, T., Palmer, C. N. A., Smith, B. H., Charge Diabetes Working Group, The EPIC-InterAct Consortium, EPIC-CVD Consortium, GOLD Consortium, VA Million Veteran Program, Kathiresan, S. & Willer, C. J., 30 Oct 2017, In: Nature Genetics. 49, 12, p. 1758-1766 9 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File

  • Exome
  • Lipids
  • Coronary Artery Disease
  • Triglycerides
  • Type 2 Diabetes Mellitus
  180 Citations (Scopus)

  215 Downloads (Pure)

• Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants

  Nagy, R., Boutin, T. S., Marten, J., Huffman, J. E., Kerr, S. M., Campbell, A., Evenden, L., Gibson, J., Amador, C., Howard, D. M., Navarro, P., Morris, A., Deary, I. J., Hocking, L. J., Padmanabhan, S., Smith, B. H., Joshi, P., Wilson, J. F., Hastie, N. D., Wright, A. F. & 5 others, McIntosh, A. M., Porteous, D. J., Haley, C. S., Vitart, V. & Hayward, C., 7 Mar 2017, In: Genome Medicine. 9, p. 1-14 14 p., 23.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Scotland
  • Genome-Wide Association Study
  • Family Health
  • Haplotypes
  • National Health Programs
  46 Citations (Scopus)

  154 Downloads (Pure)

• Genetic variation in hyperpolarization-activated cyclic nucleotide-gated channels and its relationship with neuroticism, cognition and risk of depression

  McIntosh, A. M., Simen, A. A., Evans, K. L., Hall, J., MacIntyre, D. J., Blackwood, D., Morris, A. D., Smith, B. H., Dominiczak, A., Porteous, D., Deary, I. J. & Thomson, P. A., 2012, In: Frontiers in Genetics. 3, 00116.

  Research output: Contribution to journal › Article › peer-review

  • Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
  • Neuroticism
  • Genetic Variation
  • Cognition
  • Depression
  6 Citations (Scopus)

• Genome-wide association analysis identifies six new loci associated with forced vital capacity

  Loth, D. W., Artigas, M. S., Gharib, S. A., Wain, L. V., Franceschini, N., Koch, B., Pottinger, T. D., Smith, A. V., Duan, Q., Oldmeadow, C., Lee, M. K., Strachan, D. P., James, A. L., Huffman, J. E., Vitart, V., Ramasamy, A., Wareham, N. J., Kaprio, J., Wang, X-Q., Trochet, H. & 33 others, Kähönen, M., Flexeder, C., Albrecht, E., Lopez, L. M., de Jong, K., Thyagarajan, B., Alves, A. C., Enroth, S., Omenaas, E., Joshi, P. K., Fall, T., Viñuela, A., Launer, L. J., Loehr, L. R., Fornage, M., Li, G., Wilk, J. B., Tang, W., Manichaikul, A., Lahousse, L., Harris, T. B., North, K. E., Rudnicka, A. R., Hui, J., Gu, X., Lumley, T., Wright, A. F., Hastie, N. D., Campbell, S., Generation Scotland, Smith, B. H., Tobin, M. D. & London, S. J., Jul 2014, In: Nature Genetics. 46, 7, p. 669-677 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Vital Capacity
  • Genome-Wide Association Study
  • Lung
  • Lung Diseases
  • Hispanic Americans
  88 Citations (Scopus)

• Genome-wide association for major depression through age at onset stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

  Power, R. A., Tansey, K. E., Buttenschøn, H. N., Cohen-Woods, S., Bigdeli, T., Hall, L. S., Kutalik, Z., Lee, S. H., Ripke, S., Steinberg, S., Teumer, A., Viktorin, A., Wray, N. R., Arolt, V., Baune, B. T., Boomsma, D. I., Børglum, A. D., Byrne, E. M., Castelao, E., Craddock, N. & 33 others, Craig, I. W., Dannlowski, U., Deary, I. J., Degenhardt, F., Forstner, A. J., Gordon, S. D., Grabe, H. J., Grove, J., Hamilton, S. P., Hayward, C., Heath, A. C., Hocking, L. J., Homuth, G., Hottenga, J. J., Kloiber, S., Krogh, J., Landén, M., Lang, M., Levinson, D. F., Lichtenstein, P., Lucae, S., MacIntyre, D. J., Madden, P., Magnusson, P. K. E., Martin, N. G., McIntosh, A. M., Middeldorp, C. M., Milaneschi, Y., Montgomery, G. W., Smith, B. H., CONVERGE Consortium, CARDIoGRAM Consortium & GERAD1 Consortium, 15 Feb 2017, In: Biological Psychiatry. 81, 4, p. 325-335 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Major Depressive Disorder
  • Genomics
  • Age of Onset
  • Psychiatry
  • Genome
  92 Citations (Scopus)

  315 Downloads (Pure)

• Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region

  Peters, M. J., Broer, L., Willemen, H. L. D. M., Eiriksdottir, G., Hocking, L. J., Holliday, K. L., Horan, M. A., Meulenbelt, I., Neogi, T., Popham, M., Schmidt, C. O., Soni, A., Valdes, A. M., Amin, N., Dennison, E. M., Eijkelkamp, N., Harris, T. B., Hart, D. J., Hofman, A., Huygen, F. J. P. M. & 32 others, Jameson, K. A., Jones, G. T., Launer, L. J., Kerkhof, H. J. M., De Kruijf, M., McBeth, J., Kloppenburg, M., Ollier, W. E., Oostra, B., Payton, A., Rivadeneira, F., Smith, B. H., Smith, A. V., Stolk, L., Teumer, A., Thomson, W., Uitterlinden, A. G., Wang, K., Van Wingerden, S. H., Arden, N. K., Cooper, C., Felson, D., Gudnason, V., Macfarlane, G. J., Pendleton, N., Slagboom, P. E., Spector, T. D., Völzke, H., Kavelaars, A., Van Duijn, C. M., Williams, F. M. K. & Van Meurs, J. B. J., Mar 2013, In: Annals of the Rheumatic Diseases. 72, 3, p. 427-436 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Chronic Pain
  • Genes
  • Meta-Analysis
  • Chaperonins
  68 Citations (Scopus)

• Genome­-wide association study of alcohol consumption and genetic overlap with other health-­related traits in UK Biobank (N =112,117)

  Clarke, T. K., Adams, M. J., Davies, G., Howard, D. M., Hall, L. S., Padmanabhan, S., Smith, B. H., Hayward, C., Porteous, D. J., Deary, I. J. & McIntosh, A. M., Oct 2017, In: Molecular Psychiatry. 22, 10, p. 1376-1384 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Genome-Wide Association Study
  • Alcohol Drinking
  • Health
  • Genes
  • Single Nucleotide Polymorphism
  135 Citations (Scopus)

  212 Downloads (Pure)

• Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

  Howard, D. M., Hall, L. S., Hafferty, J. D., Yanni, Z., Adams, M. J., Clarke, T-K., Porteous, D. J., Nagy, R., Hayward, C., Smith, B., Murray, A. D., Ryan, N. M., Evans, K. L., Haley, C. S., Deary, I. J., Thomson, P. A. & McIntosh, A. M., 30 Nov 2017, In: Translational Psychiatry. 7, p. 1-9 9 p., 1263.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Scotland
  • Major Depressive Disorder
  • Haplotypes
  • Genome
  • Genome-Wide Association Study
  7 Citations (Scopus)

  155 Downloads (Pure)

• Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

  Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., Shen, X., Gandin, I., McDaid, A. F., Hansen, T. F., Gordon, S. D., Giulianini, F., Boutin, T. S., Abdellaoui, A., Zhao, W., Medina-Gomez, C. & 93 others, Bartz, T. M., Trompet, S., Lange, L. A., Raffield, L., van der Spek, A., Galesloot, T. E., Proitsi, P., Yanek, L. R., Bielak, L. F., Payton, A., Murgia, F., Concas, M. P., Biino, G., Tajuddin, S. M., Seppälä, I., Amin, N., Boerwinkle, E., Børglum, A. D., Campbell, A., Demerath, E. W., Demuth, I., Faul, J. D., Ford, I., Gialluisi, A., Gögele, M., Graff, M., Hingorani, A. D., Hottenga, J. J., Hougaard, D. M., Hurme, M. A., Ikram, M. A., Jylhä, M., Kuh, D., Ligthart, L., Lill, C. M., Lindenberger, U., Lumley, T., Mägi, R., Marques-Vidal, P., Medland, S. E., Milani, L., Nagy, R., Ollier, W. E. R., Peyser, P. A., Pramstaller, P. P., Ridker, P. M., Rivadeneira, F., Ruggiero, D., Saba, Y., Schmidt, R., Schmidt, H., Slagboom, P. E., Smith, B. H., Smith, J. A., Sotoodehnia, N., Steinhagen-Thiessen, E., van Rooij, F. J. A., Verbeek, A. L., Vermeulen, S. H., Vollenweider, P., Wang, Y., Werge, T., Whitfield, J. B., Zonderman, A. B., Lehtimäki, T., Evans, M. K., Pirastu, M., Fuchsberger, C., Bertram, L., Pendleton, N., Kardia, S. L. R., Ciullo, M., Becker, D. M., Wong, A., Psaty, B. M., van Duijn, C. M., Wilson, J. G., Jukema, J. W., Kiemeney, L. A., Uitterlinden, A. G., Franceschini, N., North, K. E., Weir, D. R., Metspalu, A., Boomsma, D. I., Hayward, C., Chasman, D. I., Martin, N. G., Sattar, N., Campbell, H., Esko, T., Kutalik, Z. & Wilson, J. F., 13 Oct 2017, In: Nature Communications. 8, p. 1-13 13 p., 910.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • HLA-DQA1 antigen
  • HLA-DRB1 Chains
  • genome
  • coronary artery disease
  • Human engineering
  53 Citations (Scopus)

  223 Downloads (Pure)

• Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

  Justice, A. E., Winkler, T. W., Feitosa, M. F., Graff, M., Fisher, V. A., Young, K. L., Barata, L., Deng, X., Czajkowski, J., Hadley, D., Ngwa, J. S., Ahluwalia, T. S., Chu, A. Y., Heard-Costa, N. L., Lim, E., Perez, J., Eicher, J. D., Kutalik, Z., Xue, L., Mahajan, A. & 297 others, Renström, F., Wu, J. M. W., Qi, Q., Ahmad, S., Alfred, T., Amin, N., Bielak, L. F., Bonnefond, A., Bragg-Gresham, J. L., Cadby, G., Chittani, M., Coggeshall, S., Corre, T., Direk, N., Eriksson, J., Fischer, K., Gorski, M., Neergaard Harder, M., Horikoshi, M., Huang, T., Huffman, J. E., Jackson, A. U., Justesen, J. M., Kanoni, S., Kinnunen, L., Kleber, M. E., Komulainen, P., Kumari, M., Lim, U., Luan, J., Lyytikäinen, L-P., Mangino, M., Manichaikul, A., Marten, J., Middelberg, R. P. S., Müller-Nurasyid, M., Navarro, P., Pérusse, L., Pervjakova, N., Sarti, C., Smith, A. V., Smith, J. A., Stančáková, A., Strawbridge, R. J., Stringham, H. M., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., van der Laan, S. W., van der Most, P. J., van Vliet-Ostaptchouk, J. V., Vedantam, S. L., Verweij, N., Vink, J. M., Vitart, V., Wu, Y., Yengo, L., Zhang, W., Hua Zhao, J., Zimmermann, M. E., Zubair, N., Abecasis, G. R., Adair, L. S., Afaq, S., Afzal, U., Bakker, S. J. L., Bartz, T. M., Beilby, J. P., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E. P., Braga, D., Buckley, B. M., Buyske, S., Campbell, H., Chambers, J. C., Collins, F. S., Curran, J. E., de Borst, G. J., de Craen, A. J. M., de Geus, E. J. C., Dedoussis, G., Delgado, G. E., den Ruijter, H. M., Eiriksdottir, G., Eriksson, A. L., Esko, T., Faul, J. D., Ford, I., Forrester, T., Gertow, K., Gigante, B., Glorioso, N., Gong, J., Grallert, H., Grammer, T. B., Grarup, N., Haitjema, S., Hallmans, G., Hamsten, A., Hansen, T., Harris, T. B., Hartman, C. A., Hassinen, M., Hastie, N. D., Heath, A. C., Hernandez, D., Hindorff, L. A., Hocking, L. J., Hollensted, M., Holmen, O. L., Homuth, G., Jan Hottenga, J., Huang, J., Hung, J., Hutri-Kähönen, N., Ingelsson, E., James, A. L., Jansson, J-O., Jarvelin, M-R., Jhun, M. A., Jørgensen, M. E., Juonala, M., Kähönen, M., Karlsson, M., Koistinen, H. A., Kolcic, I., Kolovou, G., Kooperberg, C., Krämer, B. K., Kuusisto, J., Kvaløy, K., Lakka, T. A., Langenberg, C., Launer, L. J., Leander, K., Lee, N. R., Lind, L., Lindgren, C. M., Linneberg, A., Lobbens, S., Loh, M., Lorentzon, M., Luben, R. N., Lubke, G., Ludolph-donislawski, A., Lupoli, S., Madden, P. A. F., Männikkö, R., Marques-Vidal, P., Martin, N. G., McKenzie, C. A., McKnight, B., Mellström, D., Menni, C., Montgomery, G. W., Musk, A. ., Narisu, N., Nauck, M., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Peyser, P. A., Pisinger, C., Porteous, D. J., Raitakari, O. T., Rankinen, T., Rao, D. C., Rasmussen-Torvik, L. J., Rawal, R., Rice, T. K., Ridker, P. M., Rose, L. M., Bien, S. A., Rudan, I., Sanna, S., Sarzynski, M. A., Sattar, N., Savonen, K., Schlessinger, D., Scholtens, S., Schurmann, C., Scott, R. A., Sennblad, B., Siemelink, M. A., Silbernagel, G., Slagboom, P. E., Snieder, H., Staessen, J. A., Stott, D. J., Swertz, M. A., Swift, A. J., Taylor, K. D., Tayo, B. O., Thorand, B., Thuillier, D., Tuomilehto, J., Uitterlinden, A. G., Vandenput, L., Vohl, M-C., Völzke, H., Vonk, J. M., Waeber, G., Waldenberger, M., Westendorp, R. G. J., Wild, S. H., Willemsen, G., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zhao, W., Zillikens, M. C., Baldassarre, D., Balkau, B., Bandinelli, S., Böger, C. A., Boomsma, D. I., Bouchard, C., Bruinenberg, M., Chasman, D. I., Chen, Y., Chines, P. S., Cooper, R. S., Cucca, F., Cusi, D., de Faire, U., Ferrucci, L., Franks, P. W., Froguel, P., Gordon-Larsen, P., Grabe, H-J., Gudnason, V., Haiman, C. A., Hayward, C., Hveem, K., Johnson, A. D., Wouter Jukema, J., Kardia, S. L. R., Kivimaki, M., Kooner, J. S., Kuh, D., Laakso, M., Lehtimäki, T., Marchand, L. L., März, W., McCarthy, M. I., Metspalu, A., Morris, A. P., Ohlsson, C., Palmer, L. J., Pasterkamp, G., Pedersen, O., Peters, A., Peters, U., Polasek, O., Psaty, B. M., Qi, L., Rauramaa, R., Smith, B. H., Sørensen, T. I. A., Strauch, K., Tiemeier, H., Tremoli, E., van der Harst, P., Vestergaard, H., Vollenweider, P., Wareham, N. J., Weir, D. R., Whitfield, J. B., Wilson, J. F., Tyrrell, J., Frayling, T. M., Barroso, I., Boehnke, M., Deloukas, P., Fox, C. S., Hirschhorn, J. N., Hunter, D. J., Spector, T. D., Strachan, D. P., van Duijn, C. M., Heid, I. M., Mohlke, K. L., Marchini, J. L., Loos, R. J. F., Kilpeläinen, T. O., Liu, C-T., Borecki, I. B., North, K. E. & Cupples, L. A., 26 Apr 2017, In: Nature Communications. 8, 19 p., 14977.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • obesity
  • genome
  • loci
  • Genome-Wide Association Study
  • Adiposity
  63 Citations (Scopus)

  143 Downloads (Pure)

• Genome-wide physical activity interactions in adiposity: A meta-analysis of 200,452 adults

  Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., Den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D. & 31 others, Hayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, J. M., Kleber, M. E., Hollensted, M., Lohman, K., Rivera, N. V., Whitfield, J. B., Zhao, J. H., Stringham, H. M., Lyytikäinen, L-P., Huppertz, C., Willemsen, G., Smith, B. H. & CHARGE Consortium, EPIC-InterAct Consortium, PAGE Consortium , 27 Apr 2017, In: PLoS Genetics. 13, 4, 26 p., e1006528.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • adiposity
  • physical activity
  • meta-analysis
  • Adiposity
  • genome
  73 Citations (Scopus)

  164 Downloads (Pure)

• Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated with Major Depressive Disorder

  Yanni, Z., Navarro, P., Shirali, M., Howard, D. M., Adams, M. J., Hall, L. S., Clarke, T-K., Thomson, P. A., Smith, B. H., Murray, A., Padmanabhan, S., Hayward, C., Boutin, T., MacIntyre, D. J., Lewis, C. M., Wray, N. R., Mehta, D., Penninx, B. W. J. H., Milaneschi, Y., Baune, B. T. & 20 others, Air, T., Hottenga, J-J., Mbarek, H., Castelao, E., Pistis, G., Schulze, T. G., Streit, F., Forstner, A. J., Byrne, E. M., Martin, N. G., Breen, G., Müller-Myhsok, B., Lucae, S., Kloiber, S., Domenici, E., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Deary, I. J., Porteous, D. J., Haley, C. S. & McIntosh, A. M., 1 Sep 2017, In: Biological Psychiatry. 82, 5, p. 312-321 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Major Depressive Disorder
  • Haplotypes
  • Genome
  • Single Nucleotide Polymorphism
  • Genes
  121 Downloads (Pure)

• Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK Biobank

  Howard, D. M., Adams, M. J., Clarke, T-K., Wigmore, E. M., Zeng, Y., Hagenaars, S. P., Lyall, D. M., Thomson, P. A., Evans, K. L., Porteous, D. J., Nagy, R., Hayward, C., Haley, C. S., Smith, B. H., Murray, A. D., Batty, G. D., Deary, I. J. & McIntosh, A. M., 10 Aug 2017, In: Wellcome Open Research. 2, p. 1-13 13 p., 61.

  Research output: Contribution to journal › Article › peer-review

  File

  • Scotland
  • Haplotypes
  • Genes
  • Longitudinal Studies
  • Aging of materials
  3 Citations (Scopus)

  143 Downloads (Pure)

• Heritability of chronic pain in 2195 extended families

  Hocking, L. J., Morris, A. D., Dominiczak, A. F., Porteous, D. J., Smith, B. H. & Generation Scotland, Aug 2012, In: European Journal of Pain. 16, 7, p. 1053-1063 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Chronic Pain
  • Scotland
  • Family Health
  • Occupations
  • Social Adjustment
  45 Citations (Scopus)

• "I feel so stupid because I can't give a proper answer..." How older adults describe chronic pain: a qualitative study

  Clarke, A., Anthony, G., Gray, D., Jones, D., McNamee, P., Schofield, P., Smith, B. H. & Martin, D., 2012, In: BMC Geriatrics. 12, 1, 78.

  Research output: Contribution to journal › Article › peer-review

  • Chronic Pain
  • Pain
  • Metaphor
  • Interviews
  • Scotland
  16 Citations (Scopus)

• Investigating shared aetiology between type 2 diabetes and major depressive disorder in a population based cohort

  Clarke, T-K., Obsteter, J., Hall, L. S., Hayward, C., Thomson, P. A., Smith, B. H., Padmanabhan, S., Hocking, L. J., Deary, I. J., Porteous, D. J. & McIntosh, A. M., Apr 2017, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 174, 3, p. 227-234 8 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Major Depressive Disorder
  • Type 2 Diabetes Mellitus
  • Population
  • Single Nucleotide Polymorphism
  • Medical Genetics
  13 Citations (Scopus)

  164 Downloads (Pure)

• "I try and smile, I try and be cheery, I try not to be pushy. I try to say 'I'm here for help' but I leave feeling… worried": a qualitative study of perceptions of interactions with health professionals by community-based older adults with chronic pain

  Clarke, A., Martin, D., Jones, D., Schofield, P., Anthony, G., McNamee, P., Gray, D. & Smith, B. H., Sep 2014, In: PLoS ONE. 9, 9, 7 p., e105450.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • health care workers
  • pain
  • Chronic Pain
  • Emotions
  • Health
  15 Citations (Scopus)

  201 Downloads (Pure)

• Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

  Christophersen, I. E., Rienstra, M., Roselli, C., Yin, X., Geelhoed, B., Barnard, J., Lin, H., Arking, D. E., Smith, A. V., Albert, C. M., Chaffin, M., Tucker, N. R., Li, M., Klarin, D., Bihlmeyer, N. A., Low, S-K., Weeke, P. E., Mueller-Nurasyid, M., Smith, J. G., Brody, J. A. & 142 others, Niemeijer, M. N., Doerr, M., Trompet, S., Huffman, J. E., Gustafsson, S., Schurmann, C., Kleber, M. E., Lyytikainen, L-P., Seppala, I., Malik, R., Horimoto, A. R. V. R., Perez, M., Sinisalo, J., Aeschbacher, S., Theriault, S., Yao, J., Radmanesh, F., Weiss, S., Teumer, A., Choi, S. H., Weng, L-C., Clauss, S., Deo, R., Rader, D. J., Shah, S. H., Sun, A., Hopewell, J. C., Debette, S., Chauhan, G., Yang, Q., Worrall, B. B., Pare, G., Kamatani, Y., Hagemeijer, Y. P., Verweij, N., Siland, J. E., Kubo, M., Smith, J. D., Van Wagoner, D. R., Bis, J. C., Perz, S., Psaty, B. M., Ridker, P. M., Magnani, J. W., Harris, T. B., Launer, L. J., Shoemaker, M. B., Padmanabhan, S., Haessler, J., Bartz, T. M., Waldenberger, M., Lichtner, P., Arendt, M., Krieger, J. E., Kahonen, M., Risch, L., Mansur, A. J., Peters, A., Smith, B. H., Lind, L., Scott, S. A., Lu, Y., Bottinger, E. B., Hernesniemi, J., Lindgren, C. M., Wong, J. A., Huang, J., Eskola, M., Morris, A. P., Ford, I., Reiner, A. P., Delgado, G., Chen, L. Y., Chen, Y-D. I., Sandhu, R. K., Li, M., Boerwinkle, E., Eisele, L., Lannfelt, L., Rost, N., Anderson, C. D., Taylor, K. D., Campbell, A., Magnusson, P. K. E., Porteous, D. J., Hocking, L. J., Vlachopoulou, E., Pedersen, N. L., Nikus, K., Orho-Melander, M., Hamsten, A., Heeringa, J., Denny, J. C., Kriebel, J., Darbar, D., Newton-Cheh, C., Shaffer, C. M., Macfarlane, P. W., Heilmann-Heimbach, S., Almgren, P., Huang, P. L., Sotoodehnia, N., Soliman, E. Z., Uitterlinden, A. G., Hofman, A., Franco, O. H., Voelker, U., Joeckel, K-H., Sinner, M. F., Lin, H. J., Guo, X., Dichgans, M., Ingelsson, E., Kooperberg, C., Melander, O., Loos, R. J. F., Laurikka, J., Conen, D., Rosand, J., van der Harst, P., Lokki, M-L., Kathiresan, S., Pereira, A., Jukema, J. W., Hayward, C., Rotter, J. I., Maerz, W., Lehtimaki, T., Stricker, B. H. C., Chung, M. K., Felix, S. B., Gudnason, V., Alonso, A., Roden, D. M., Kaeaeb, S., Chasman, D. I., Heckbert, S. R., Benjamin, E. J., Tanaka, T., Lunetta, K. L., Lubitz, S. A. & Ellinor, P. T., Jun 2017, In: Nature Genetics. 49, 6, p. 946-952 7 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File
  122 Citations (Scopus)

  350 Downloads (Pure)

• Lessons from Mackenzie that still resonate

  Van Hecke, O., Smith, B. H. & Sullivan, F. M., Mar 2013, In: British Journal of General Practice. 63, 608, p. 158-159 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • General Practitioners
  • Primary Health Care
  • Epidemiology
  • Medicine
  • Research Personnel

• Managing chronic pain in the non-specialist setting: a new SIGN guideline

  Smith, B. H., Hardman, J. D., Stein, A., Colvin, L. & SIGN Chronic Pain Guideline Development Group, 1 Jul 2014, In: British Journal of General Practice. 64, 624, p. e462-e464 3 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Molecular genetic contributions to socioeconomic status and intelligence

  Marioni, R. E., Davies, G., Hayward, C., Liewald, D., Kerr, S. M., Campbell, A., Luciano, M., Smith, B. H., Padmanabhan, S., Hocking, L. J., Hastie, N. D., Wright, A. F., Porteous, D. J., Visscher, P. M. & Deary, I. J., 2014, In: Intelligence. 44, May-June, p. 26-32 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Molecular Genetics
  • Socioeconomic Status
  • Intelligence
  • Social Class
  • Molecular Biology
  79 Citations (Scopus)

  157 Downloads (Pure)

• NeuPSIG: investing in solutions to the growing global challenge of neuropathic pain

  Smith, B. & Raja, S. N., 1 Oct 2017, In: British Journal of Anaesthesia. 119, 4, p. 705-708 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  2 Citations (Scopus)

  98 Downloads (Pure)

• Neuropathic pain: a pathway for care developed by the British Pain Society

  Smith, B. H., Lee, J., Price, C. & Baranowski, A. P., Jul 2013, In: British Journal of Anaesthesia. 111, 1, p. 73-79 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuralgia
  • Pain
  • Secondary Care
  • Tertiary Healthcare
  • Consensus
  25 Citations (Scopus)

• Neuropathic pain in the community: more under-treated than refractory?

  Torrance, N., Ferguson, J. A., Afolabi, E., Bennett, M. I., Serpell, M. G., Dunn, K. M. & Smith, B. H., May 2013, In: Pain. 154, 5, p. 690–699 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuralgia
  • Chronic Pain
  • Pain
  • Self Efficacy
  • Signs and Symptoms
  94 Citations (Scopus)

• Neuropathic pain in the general population: a systematic review of epidemiological studies

  van Hecke, O., Austin, S. K., Khan, R. A., Smith, B. H. & Torrance, N., Apr 2014, In: Pain. 155, 4, p. 654-662 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuralgia
  • Epidemiologic Studies
  • Systematic Reviews
  • Population
  • Glossopharyngeal Nerve Diseases
  511 Citations (Scopus)