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  Aminoglycosides restore full-length type VII collagen by overcoming premature termination codons: therapeutic implications for dystrophic epidermolysis bullosa

  Cogan, J., Weinstein, J., Wang, X., Hou, Y., Martin, S., South, A. P., Woodley, D. T. & Chen, M., 23 Jul 2014, In: Molecular Therapy. 22, 10, p. 1741-1752 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Collagen Type VII
  • Epidermolysis Bullosa Dystrophica
  • Nonsense Codon
  • Aminoglycosides
  • Skin
  37 Citations (Scopus)

• A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo

  Oi, K., Sohara, E., Rai, T., Misawa, M., Chiga, M., Alessi, D. R., Sasaki, S. & Uchida, S., 15 Dec 2012, In: Open Biology. 1, 2, p. 120-127 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Phosphorylation
  • symporters
  • Symporters
  • Nutrition
  • Knockout Mice
  37 Citations (Scopus)

  145 Downloads (Pure)

• A mobile phone intervention to reduce binge drinking among disadvantaged men: study protocol for a randomised controlled cost-effectiveness trial

  Crombie, I. K., Irvine, L., Williams, B., Sniehotta, F. F., Petrie, D., Evans, J. M. M., Emslie, C., Jones, C., Ricketts, I. W., Humphris, G., Norrie, J., Rice, P. & Slane, P. W., 19 Dec 2014, In: Trials. 15, 8 p., 494.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Binge Drinking
  • Cell Phone
  • Vulnerable Populations
  • Cost-Benefit Analysis
  • Text Messaging
  7 Citations (Scopus)

  170 Downloads (Pure)

• A model based criterion for gene expression calls using RNA-seq data

  Wagner, G. P., Kin, K. & Lynch, V. J., Sep 2013, In: Theory in Biosciences. 132, 3, p. 159-164 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Gene Expression
  • RNA
  • gene expression
  • Gene expression
  • Gene
  78 Citations (Scopus)

• A model for dynamic reconfiguration in service-oriented architectures

  Fiadeiro, J. L. & Lopes, A., 1 May 2013, In: Software and Systems Modeling. 12, 2, p. 349-367 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Service-oriented Architecture
  • Dynamic Reconfiguration
  • Service-oriented
  • Service oriented architecture (SOA)
  • Architecture
  26 Citations (Scopus)

• A model for the energy bands of an "open"-type periodic structure: A periodic viaduct coupled with the half-space

  Lu, J-F., Li, J-H. & Jeng, D-S., 1 Feb 2012, In: Acta Mechanica. 223, 2, p. 257-277 21 p.

  Research output: Contribution to journal › Article › peer-review

  • Band structure
  • Periodic structures
  • Transfer matrix method
  • Piers
  • Acoustic impedance
  1 Citation (Scopus)

• A model of consultation in prostate cancer care: evidence from a systematic review

  Paterson, C. & Nabi, G., 2017, In: Cancer Nursing. 40, 4, p. 276-288 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Prostatic Neoplasms
  • Systematic Reviews
  • Referral and Consultation
  • Self-Management
  • Nurse Specialists
  13 Citations (Scopus)

  406 Downloads (Pure)

• A model of the transformative journey into reflexivity: an exploration into students' experiences of critical reflection

  Shaw, R., 15 Feb 2013, In: Reflective Practice. 14, 3, p. 319-335 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Student Experience
  • Critical Reflection
  • Reflexivity
  • Learning Communities
  • Journey
  9 Citations (Scopus)

• A Model Sheet Mineral System to Study Fungal Bioweathering of Mica

  Wei, Z., Kierans, M. & Gadd, G. M., 2012, In: Geomicrobiology Journal. 29, 4, p. 323-331 9 p.

  Research output: Contribution to journal › Article › peer-review
  21 Citations (Scopus)

• A modest proposal

  Collison, D., 2012, In: CA Magazine. May, p. 62-63 2 p.

  Research output: Contribution to journal › Article › peer-review

• A molecular explanation for the recessive nature of parkin-linked Parkinson's disease

  Spratt, D. E., Julio Martinez-Torres, R., Noh, Y. J., Mercier, P., Manczyk, N., Barber, K. R., Aguirre, J. D., Burchell, L., Purkiss, A., Walden, H. & Shaw, G. S., 1 Jan 2013, In: Nature Communications. 4, 12 p., 1983.

  Research output: Contribution to journal › Article › peer-review

  • Parkinson disease
  • mutations
  • Ubiquitin
  • Parkinsonian Disorders
  • Parkinson Disease
  88 Citations (Scopus)

• A molecular method to assess Phytophthora diversity in environmental samples

  Scibetta, S., Schena, L., Chimento, A., Cacciola, S. O. & Cooke, D. E. L., Mar 2012, In: Journal of Microbiological Methods. 88, 3, p. 356-368 13 p.

  Research output: Contribution to journal › Article › peer-review
  60 Citations (Scopus)

• A molecular switch driving inactivation in the cardiac K channel hERG

  Köpfer, D. A., Hahn, U., Ohmert, I., Vriend, G., Pongs, O., de Groot, B. L. & Zachariae, U., 24 Jul 2012, In: PLoS ONE. 7, 7, e41023.

  Research output: Contribution to journal › Article › peer-review

  • Hydrogen bonds
  • Hydrogen
  • Action Potentials
  • inactivation
  • selectivity (chemistry)
  14 Citations (Scopus)

• A Morphological identification cell cytotoxicity assay using cytoplasm-localized fluorescent probe (CLFP) to distinguish living and dead cells

  Lai, F., Shen, Z., Wen, H., Chen, J., Zhang, X., Lin, P., Yin, D., Cui, H. & Chen, X., 8 Jan 2017, In: Biochemical and Biophysical Research Communications. 482, 2, p. 257-263 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cytotoxicity
  • Assays
  • Fluorescent Dyes
  • Cytoplasm
  • Cells
  10 Citations (Scopus)

  410 Downloads (Pure)

• AMP-activated protein kinase (AMPK)α2 plays a role in determining the cellular fate of glucose in insulin-resistant mouse skeletal muscle

  Lee-Young, R. S., Bonner, J. S., Mayes, W. H., Iwueke, I., Barrick, B. A., Hasenour, C. M., Kang, L. & Wasserman, D. H., Mar 2013, In: Diabetologia. 56, 3, p. 608-617 10 p.

  Research output: Contribution to journal › Article › peer-review

  • AMP-Activated Protein Kinases
  • Skeletal Muscle
  • Insulin
  • Nitric Oxide Synthase Type II
  • Lipids
  18 Citations (Scopus)

• AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner

  Vlachaki Walker, J. M., Robb, J. L., Cruz, A. M., Malhi, A., Weightman Potter, P. G., Ashford, M. L. J., McCrimmon, R. J., Ellacott, K. L. J. & Beall, C., 21 Apr 2017, In: Diabetes, Obesity & Metabolism. 19, 7, p. 997-1005 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • A 769662
  • AMP-Activated Protein Kinases
  • Astrocytes
  • Adenosine Triphosphate
  • Calcium
  14 Citations (Scopus)

  295 Downloads (Pure)

• AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

  Bultot, L., Guigas, B., Von Wilamowitz-Moellendorff, A., Maisin, L., Vertommen, D., Hussain, N., Beullens, M., Guinovart, J. J., Foretz, M., Viollet, B., Sakamoto, K., Hue, L. & Rider, M. H., 1 Apr 2012, In: Biochemical Journal. 443, p. 193-203 11 p.

  Research output: Contribution to journal › Article › peer-review
  59 Citations (Scopus)

• AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation

  Gowans, G. J., Hawley, S. A., Ross, F. A. & Hardie, D. G., 1 Oct 2013, In: Cell Metabolism. 18, 4, p. 556-566 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Adenosine Monophosphate
  • Phosphorylation
  • Adenosine Diphosphate
  • Adenosine Triphosphate
  275 Citations (Scopus)

  167 Downloads (Pure)

• AMPK: regulating energy balance at the cellular and whole body levels

  Hardie, D. G. & Ashford, M. L. J., Mar 2014, In: Physiology. 29, 2, p. 99-107 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Adenine Nucleotides
  • AMP-Activated Protein Kinases
  • Eukaryota
  • Energy Intake
  • Energy Metabolism
  162 Citations (Scopus)

  166 Downloads (Pure)

• AMPK: a target for drugs and natural products with effects on both diabetes and cancer

  Hardie, D. G., Jul 2013, In: Diabetes. 62, 7, p. 2164-2172 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Biological Products
  • Metformin
  • Pharmaceutical Preparations
  • Salicylates
  264 Citations (Scopus)

  143 Downloads (Pure)

• AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?

  Dandapani, M. & Hardie, D. G., Apr 2013, In: Biochemical Society Transactions. 41, 2, p. 687-693 7 p.

  Research output: Contribution to journal › Article › peer-review
  34 Citations (Scopus)

• AMPK activators inhibit the proliferation of human melanomas bearing the activated MAPK pathway

  Petti, C., Vegetti, C., Molla, A., Bersani, I., Cleris, L., Mustard, K. J., Formelli, F., Hardie, G. D., Sensi, M. & Anichini, A., 2012, In: Melanoma Research. 22, 5, p. 341-350 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Melanoma
  • acadesine
  • 4-aminoimidazole
  • Phenformin
  • Mitogen-Activated Protein Kinase Kinases
  34 Citations (Scopus)

• AMPK modulates glucose-sensing in insulin-secreting cells by altered phosphotransfer to KATP channels

  Beall, C., Watterson, K. R., McCrimmon, R. J. & Ashford, M. L. J., Jun 2013, In: Journal of Bioenergetics and Biomembranes. 45, 3, p. 229-241 13 p.

  Research output: Contribution to journal › Article › peer-review

  • KATP Channels
  • AMP-Activated Protein Kinases
  • Insulin-Secreting Cells
  • Glucose
  • Adenylate Kinase
  14 Citations (Scopus)

• AMPK promotes p53 acetylation via phosphorylation and inactivation of SIRT1 in liver cancer cells

  Lee, C-W., Wong, L. L-Y., Tse, E. Y-T., Liu, H-F., Leong, V. Y-L., Lee, J. M-F., Hardie, D. G., Ng, I. O-L. & Ching, Y-P., 2012, In: Cancer Research. 72, 17, p. 4394-4404 11 p.

  Research output: Contribution to journal › Article › peer-review

  • AMP-Activated Protein Kinases
  • Acetylation
  • Liver Neoplasms
  • Phosphorylation
  • Hepatocellular Carcinoma
  132 Citations (Scopus)

• AMPK-sensing energy while talking to other signaling pathways

  Hardie, D. G., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 939-952 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Mechanistic Target of Rapamycin Complex 1
  • Nutrients
  • AMP-activated protein kinase kinase
  • Eukaryota
  317 Citations (Scopus)

  159 Downloads (Pure)

• AMPKα1: a glucose sensor that controls CD8 T-cell memory

  Rolf, J., Zarrouk, M., Finlay, D. K., Foretz, M., Viollet, B. & Cantrell, D. A., Apr 2013, In: European Journal of Immunology. 43, 4, p. 889-896 8 p.

  Research output: Contribution to journal › Article › peer-review
  138 Citations (Scopus)

• A Multi-disciplinary Approach to the Archaeological Investigation of a Bedrock-Dominated Shallow-Marine Landscape: An example from the Bay of Firth, Orkney, UK

  Bates, M. R., Nayling, N., Bates, R., Dawson, S., Huws, D. & Wickham-Jones, C., Mar 2013, In: International Journal of Nautical Archaeology. 42, 1, p. 24-43 20 p.

  Research output: Contribution to journal › Article › peer-review

  • Orkney
  • Archaeological Investigation
  • archaeology
  • bedrock
  • Coastal Geomorphology
  22 Citations (Scopus)

• A multidisciplinary intervention to reduce antibiotic duration in lower respiratory tract infections

  Murray, C., Shaw, A., Lloyd, M., Smith, R. P., Fardon, T. C., Schembri, S. & Chalmers, J. D., Feb 2014, In: Journal of Antimicrobial Chemotherapy. 69, 2, p. 515-518 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Respiratory Tract Infections
  • Anti-Bacterial Agents
  • Microbial Drug Resistance
  29 Citations (Scopus)

• A multifaceted intervention to improve sepsis management in general hospital wards with evaluation using segmented regression of interrupted time series

  Marwick, C. A., Guthrie, B., Pringle, J. E. C., Evans, J. M. M., Nathwani, D., Donnan, P. T. & Davey, P. G., Dec 2014, In: BMJ Quality & Safety. 23, 12, 8 p., e2.

  Research output: Contribution to journal › Article › peer-review

  • Interrupted Time Series Analysis
  • Patients' Rooms
  • General Hospitals
  • Sepsis
  • Anti-Bacterial Agents
  13 Citations (Scopus)

• A multiscale approach to curvature modulated sorting in biological membranes

  Mercker, M., Ptashnyk, M., Kuhnle, J., Hartmann, D., Weiss, M. & Jager, W., May 2012, In: Journal of Theoretical Biology. 301, 5, p. 67-82 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Biological membranes
  • Sorting
  • sorting
  • Membrane
  • Curvature
  18 Citations (Scopus)

• A multiscale mathematical model of tumour invasive growth

  Peng, L., Trucu, D., Lin, P., Thompson, A. & Chaplain, M. A. J., Mar 2017, In: Bulletin of Mathematical Biology. 79, 3, p. 389-429 41 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Multiscale Model
  • Tumor
  • tumor
  • Tumors
  • Cancer
  17 Citations (Scopus)

  178 Downloads (Pure)

• A multiscale moving boundary model arising in cancer invasion

  Trucu, D., Lin, P., Chaplain, M. A. J. & Wang, Y., 2013, In: Multiscale Modeling and Simulation: A SIAM Interdisciplinary Journal. 11, 1, p. 309-335 27 p.

  Research output: Contribution to journal › Article › peer-review

  • Invasion
  • Moving Boundary
  • Cancer
  • Cells
  • cancer
  22 Citations (Scopus)

• A mutant O-GlcNAcase enriches Drosophila developmental regulators

  Selvan, N., Williamson, R., Mariappa, D., Campbell, D. G., Gourlay, R., Ferenbach, A. T., Aristotelous, T., Hopkins-Navratilova, I., Trost, M. & van Aalten, D. M. F., Aug 2017, In: Nature Chemical Biology. 13, 8, p. 882-887 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • hexosaminidase C
  • O-GlcNAc transferase
  • Drosophila
  • Embryonic Development
  • Proteins
  22 Citations (Scopus)

  199 Downloads (Pure)

• A mutual health service in Scotland: Do we understand fully the leadership implications?

  Howieson, B. & Fenwick, C., Jul 2014, In: Leadership in Health Services. 27, 3, p. 193-203 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Scotland
  • Health Services
  • National Health Service
  • National Health Programs
  • Government Policy
  1 Citation (Scopus)

• Anabolic resistance does not explain sarcopenia in patients with type 2 diabetes mellitus, compared with healthy controls, despite reduced mTOR pathway activity

  Cuthbertson, D. J., Babraj, J., Leese, G. & Siervo, M., Dec 2017, In: Clinical Nutrition. 36, 6, p. 1716-1719 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Sarcopenia
  • Type 2 Diabetes Mellitus
  • Essential Amino Acids
  • Muscles
  • TOR Serine-Threonine Kinases
  6 Citations (Scopus)

• An accuracy assessment of forensic computerized facial reconstruction employing cone-beam computed tomography from live subjects

  Lee, W-J., Wilkinson, C. M. & Hwang, H-S., Mar 2012, In: Journal of Forensic Sciences. 57, 2, p. 318-327 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Cone-Beam Computed Tomography
  • Skull
  • Software
  53 Citations (Scopus)

• An adaptive IEEE 802.15.4 MAC layer transmission scheme for applications with heterogeneous traffic

  Zhou, Y., He, J., Chen, K., Tang, Z. & Li, Y., Dec 2013, In: Information: An Interdisciplinary Journal in English, Japanese and Chinese . 16, 12 A, p. 8451-8456 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Access control
  • Bandwidth
  • Carrier sense multiple access
  • Data communication systems
  • Energy efficiency

• An adaptive information technology for the operative diagnostics of the tropical cyclones: solar-terrestrial coupling mechanisms

  Krapivin, V. F., Soldatov, V. Y., Varotsos, C. A. & Cracknell, A. P., 2012, In: Journal of Atmospheric and Solar-Terrestrial Physics. 89, p. 83-89 7 p.

  Research output: Contribution to journal › Article › peer-review

  • cyclones
  • information technology
  • tropical cyclone
  • sequential analysis
  • oceans
  17 Citations (Scopus)

• Anaesthesia for laryngo-tracheal surgery, including tubeless field techniques

  Pearson, K. L. & McGuire, B. E., 1 Jul 2017, In: BJA Education. 17, 7, p. 242-248 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Anesthesia
  • Airway Management
  • Safety
  • Laser Therapy
  • Larynx
  6 Citations (Scopus)

• An algorithm recommendation for the pharmacological management of allergic rhinitis in the UK: a consensus statement from an expert panel

  Lipworth, B., Newton, J., Ram, B., Small, I. & Schwarze, J., 23 Jan 2017, In: NPJ Primary Care Respiratory Medicine. 27, p. 1-8 8 p., 3.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Allergic Rhinitis
  • Consensus
  • Pharmacology
  • Primary Health Care
  • Secondary Care
  7 Citations (Scopus)

  175 Downloads (Pure)

• Analyses of groundwater flow and plant evapotranspiration in a vegetated soil slope

  Leung, A. K. & Ng, C. W. W., Dec 2013, In: Canadian Geotechnical Journal. 50, 12, p. 1204-1218 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Evapotranspiration
  • Groundwater flow
  • groundwater flow
  • evapotranspiration
  • Soils
  44 Citations (Scopus)

• Analysis of a continuous finite element method for H(curl,div)-elliptic interface problem

  Duan, H., Lin, P. & Tan, R. C. E., 2013, In: Numerische Mathematik. p. 1-37 37 p.

  Research output: Contribution to journal › Article › peer-review

  • Interface Problems
  • Curl
  • Elliptic Problems
  • Finite Element Method
  • Coercive force
  14 Citations (Scopus)

• Analysis of chain saw lubricating oils commonly used in Thailand's southern border provinces for forensic science purpose

  Choodum, A., Tripuwanard, K. & Daeid, N. N., Aug 2014, In: Forensic Science International. 241, p. 60-68 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Forensic Sciences
  • Thailand
  • Oils
  • Flame Ionization
  • Lubricants
  1 Citation (Scopus)

• Analysis of energy saving lamps for use by photosensitive individuals

  Fenton, L., Ferguson, J. & Moseley, H., 2012, In: Photochemical & Photobiological Sciences. 11, 8, p. 1346-1355 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Electric lamps
  • luminaires
  • Light emitting diodes
  • Energy conservation
  • bulbs
  13 Citations (Scopus)

• Analysis of Global RNA Synthesis at the Single Cell Level following Hypoxia

  Biddlestone, J., Druker, J., Shmakova, A., Ferguson, G., Swedlow, J. R. & Rocha, S., 13 May 2014, In: JoVE: Journal of Visualized Experiments. 87, 7 p., e51420.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • RNA
  • Hypoxia
  • Cells
  • Molecular oxygen
  • Oxygen
  2 Citations (Scopus)

  176 Downloads (Pure)

• Analysis of Hopf/Hopf bifurcations in nonlocal hyperbolic models for self-organised aggregations

  Buono, P-L. & Eftimie, R., Feb 2014, In: Mathematical Models and Methods in Applied Sciences. 24, 2, p. 327-357 31 p.

  Research output: Contribution to journal › Article › peer-review

  • Hopf bifurcation
  • Aggregation
  • Spatio-temporal Patterns
  • Hopf Bifurcation
  • Agglomeration
  17 Citations (Scopus)

• Analysis of human protein replacement stable cell lines established using snoMEN-PR vector

  Ono, M., Yamada, K., Endo, A., Avolio, F. & Lamond, A. I., 25 Apr 2013, In: PLoS ONE. 8, 4, 12 p., e62305.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  6 Citations (Scopus)

  134 Downloads (Pure)

• Analysis of hydrogenase 1 levels reveals an intimate link between carbon and hydrogen metabolism in Escherichia coli K-12

  Pinske, C., McDowall, J. S., Sargent, F. & Sawers, R. G., 2012, In: Microbiology. 158, p. 856-868 13 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• Analysis of joint force and torque for the human and non-human ape foot during bipedal walking with implications for the evolution of the foot

  Wang, W., Abboud, R. J., Günther, M. M. & Crompton, R. H., Aug 2014, In: Journal of Anatomy. 25, 2, p. 152-166 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Hominidae
  • Pongidae
  • torque
  • Torque
  • walking
  9 Citations (Scopus)

• Analysis of microcystins and microcystin genes in 60-170-year-old dried herbarium specimens of cyanobacteria

  Metcalf, J. S., Beattie, K. A., Purdie, E. L., Bryant, J. A., Irvine, L. M. & Codd, G. A., 2012, In: Harmful Algae. 15, p. 47-52 6 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)