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  • Blair Smith

A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway is Associated with Major Depressive Disorder

Zeng, Y., Navarro, P., Fernandez-Pujals, A. M., Hall, L. S., Clarke, T-K., Thomson, P. A., Smith, B. H., Hocking, L. J., Padmanabhan, S., Hayward, C., MacIntyre, D. J., Wray, N. R., Deary, I. J., Porteous, D. J., Haley, C. S., McIntosh, A. M. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 15 Feb 2017, In : Biological Psychiatry. 81, 4, p. 336-346 11 p.

Research output: Contribution to journalArticle

Open Access
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17 Citations (Scopus)
370 Downloads (Pure)

A genome-wide association study finds genetic variants associated with neck or shoulder pain in UK Biobank

Meng, W., Chan, B. W., Harris, C., Freidin, M. B., Hebert, H., Adams, M. J., Campbell, A., Hayward, C., Zheng, H., Zhang, X., Colvin, L., Hales, T., Palmer, C., Williams, F. M. K., McIntosh, A. M. & Smith, B. H., 15 Apr 2020, In : Human Molecular Genetics. 29, 8, p. 1396-1404 9 p.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
13 Downloads (Pure)

Alzheimer's disease risk factor complement receptor 1 is associated with depression

Hamilton, G., Evans, K. L., MacIntyre, D. J., Deary, I. J., Dominiczak, A., Smith, B. H., Morris, A. D., Porteous, D. J. & Thomson, P. A., 2012, In : Neuroscience Letters. 510, 1, p. 6-9 4 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Ask the experts: neuropathic pain from a primary care perspective

Smith, B. H., May 2013, In : Pain Management. 3, 3, p. 173-6 4 p.

Research output: Contribution to journalArticle

Assessing the presence of shared genetic architecture between Alzheimer's disease and major depressive disorder using genome-wide association data

Gibson, J., Russ, T. C., Adams, M. J., Clarke, T-K., Howard, D. M., Hall, L. S., Fernandez-Pujals, A. M., Wigmore, E. M., Hayward, C., Davies, G., Murray, A. D., Smith, B. H., Porteous, D. J., Deary, I. J. & McIntosh, A. M., 18 Apr 2017, In : Translational Psychiatry. 7, p. 1-8 8 p., e1094.

Research output: Contribution to journalArticle

Open Access
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13 Citations (Scopus)
188 Downloads (Pure)

Association of DISC1 variants with age of onset in a population-based sample of recurrent major depression

Thomson, P. A., MacIntyre, D. J., Hamilton, G., Dominiczak, A., Smith, B. H., Morris, A., Evans, K. L. & Porteous, D. J., Jul 2013, In : Molecular Psychiatry. 18, 7, p. 745-747 3 p.

Research output: Contribution to journalLetter

9 Citations (Scopus)

A study of National Health Service management of chronic osteoarthritis and low back pain

Hart, O. R., Uden, R. M., McMullan, J. E., Ritchie, M. S., Williams, T. D. & Smith, B. H., 2014, In : Primary Health Care Research and Development. 16, 2, p. 157-166 10 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
175 Downloads (Pure)

Author Correction: Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank

Meng, W., Adams, M. J., Palmer, C. N. A., 23andMe Research Team, Shi, J., Auton, A., Ryan, K. A., Jordan, J. M., Mitchell, B. D., Jackson, R. D., Yau, M. S., McIntosh, A. M. & Smith, B. H., 26 Mar 2020, In : Communications Biology. 3, 1, 1 p., 149.

Research output: Contribution to journalArticle

Open Access
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25 Downloads (Pure)

Can pragmatic trials help us better understand chronic pain and improve treatment?

Rowbotham, M. C., Gilron, I., Glazer, C., Rice, A. S. C., Smith, B. H., Stewart, W. F. & Wasan, A. D., May 2013, In : Pain. 154, 5, p. 643-646 4 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Cardiovascular risk factors associated with the metabolic syndrome are more prevalent in people reporting chronic pain: results from a cross-sectional general population study

Goodson, N. J., Smith, B. H., Hocking, L. J., McGilchrist, M. M., Dominiczak, A. F., Morris, A., Porteous, D. J. & Goebel, A., Sep 2013, In : Pain. 154, 9, p. 1595-1602 8 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Chronic pain, depression and cardiovascular disease linked through a shared genetic predisposition: Analysis of a family-based cohort and twin study

van Hecke, O., Hocking, L. J., Torrance, N., Campbell, A., Padmanabhan, S., Porteous, D. J., McIntosh, A. M., Burri, A. V., Tanaka, H., Williams, F. M. K. & Smith, B. H., 22 Feb 2017, In : PLoS ONE. 12, 2, 19 p., e0170653.

Research output: Contribution to journalArticle

Open Access
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19 Citations (Scopus)
176 Downloads (Pure)

Chronic pain epidemiology and its clinical relevance

van Hecke, O., Torrance, N. & Smith, B. H., 2013, In : British Journal of Anaesthesia. 111, 1, p. 13-18 6 p.

Research output: Contribution to journalArticle

220 Citations (Scopus)

Cohort profile: Generation Scotland: Scottish Family Health Study (GS:SFHS). The study, its participants and their potential for genetic research on health and illness

Smith, B. H., Campbell, A., Linksted, P., Fitzpatrick, B., Jackson, C., Kerr, S. M., Deary, I. J., Macintyre, D. J., Campbell, H., McGilchrist, M., Hocking, L. J., Wisely, L., Ford, I., Lindsay, R. S., Morton, R., Palmer, C. N. A., Dominiczak, A. F., Porteous, D. J. & Morris, A. D., Jun 2013, In : International Journal of Epidemiology. 42, 3, p. 689-700 12 p.

Research output: Contribution to journalArticle

127 Citations (Scopus)

Cohort profile: The Scottish Research Register SHARE: A register of people interested in research participation linked to NHS datasets

McKinstry, B., Sullivan, F. M., Vasishta, S., Armstrong, R., Hanley, J., Haughney, J., Philip, S., Smith, B. H., Wood, A. & Palmer, C. N. A., 1 Feb 2017, In : BMJ Open. 7, 2, p. 1-8 8 p., e013351.

Research output: Contribution to journalArticle

Open Access
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12 Citations (Scopus)
164 Downloads (Pure)

Commentary: a thesis that still warrants defence and promotion

Smith, B. H., Guthrie, B., Sullivan, F. M. & Morris, A. D., 2012, In : International Journal of Epidemiology. 41, 6, p. 1518-1522 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

Rietveld, C. A., Esko, T., Davies, G., Pers, T. H., Turley, P., Benyamin, B., Chabris, C. F., Emilsson, V., Johnson, A. D., Lee, J. J., Leeuw, C. D., Marioni, R. E., Medland, S. E., Miller, M. B., Rostapshova, O., van der Lee, S. J., Vinkhuyzen, A. A. E., Amin, N., Conley, D., Derringer, J. & 39 others, van Duijn, C. M., Fehrmann, R., Franke, L., Glaeser, E. L., Hansell, N. K., Hayward, C., Iacono, W. G., Ibrahim-Verbaas, C., Jaddoe, V., Karjalainen, J., Laibson, D., Lichtenstein, P., Liewald, D. C., Magnusson, P. K. E., Martin, N. G., McGue, M., McMahon, G., Pedersen, N. L., Pinker, S., Porteous, D. J., Posthuma, D., Rivadeneira, F., Smith, B. H., Starr, J. M., Tiemeier, H., Timpson, N. J., Trzaskowski, M., Uitterlinden, A. G., Verhulst, F. C., Ward, M. E., Wright, M. J., Davey Smith, G., Deary, I. J., Johannesson, M., Plomin, R., Visscher, P. M., Benjamin, D. J., Cesarini, D. & Koellinger, P. D., 23 Sep 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 38, p. 13790-13794 5 p.

Research output: Contribution to journalArticle

131 Citations (Scopus)

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D. & 31 others, Hayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P. M., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, J. M., Kleber, M. E., Hollensted, M., Lohman, K., Rivera, N. V., Whitfield, J. B., Zhao, J. H., Stringham, H. M., Lyytikäinen, L-P., Huppertz, C., Willemsen, G., Smith, B. H. & CHARGE Consortium, Aug 2017, In : PLoS Genetics. 13, 8, p. e1006972 1 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Corrigendum to "Neuropathic pain in the general population:a systematic review of epidemiological studies": [PAIN® 155(4) pp. 654-662 (2014)] (DOI:10.1016/j.pain.2013.11.013)

van Hecke, O., Austin, S. K., Khan, R. A., Smith, B. H. & Torrance, N., Sep 2014, In : Pain. 155, 9, p. 1907 1 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Cost-effectiveness of self-management methods for the treatment of chronic pain in an aging adult population: a systematic review of the literature

Boyers, D., McNamee, P., Clarke, A., Jones, D., Martin, D., Schofield, P. & Smith, B. H., Apr 2013, In : Clinical Journal of Pain. 29, 4, p. 366-375 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Does a history of depression actually mediate smoking-related pain? findings from a cross-sectional general population-based study

van Hecke, O., Torrance, N., Cochrane, L., Cavanagh, J., Donnan, P. T., Padmanabhan, S., Porteous, D. J., Hocking, L. & Smith, B. H., Oct 2014, In : European Journal of Pain. 18, 9, p. 1223-1230 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n=19,762), UK Biobank (n=24,048) and the English Longitudinal Study of Ageing (n=5,766)

Wigmore, E. M., Clarke, T-K., Howard, D. M., Adams, M. J., Hall, L. S., Zeng, Y., Gibson, J., Davies, G., Fernandez-Pujals, A. M., Thomson, P. A., Hayward, C., Smith, B. H., Hocking, L. J., Padmanabhan, S., Deary, I. J., Porteous, D., Nicodemus, K. K. & McIntosh, A. M., 15 Aug 2017, In : Translational Psychiatry. 7, 9 p., e1205.

Research output: Contribution to journalArticle

Open Access
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12 Citations (Scopus)
177 Downloads (Pure)

eHealth and the use of individually tailored information: a systematic review

Conway, N., Webster, C., Smith, B. & Wake, D., Sep 2017, In : Health Informatics Journal. 23, 3, p. 201-233 16 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
21 Downloads (Pure)

Epidemiology of neuropathic pain and its impact on quality of life

Smith, B. H. & Torrance, N., 1 Jun 2012, In : Current Pain and Headache Reports. 16, 3, p. 191-198 8 p.

Research output: Contribution to journalArticle

125 Citations (Scopus)

Erratum: Neuropathic pain: a pathway for care developed by the British Pain Society

Smith, B. H., Lee, J., Price, C. & Baranowski, A. P., Sep 2013, In : BRITISH JOURNAL OF ANAESTHESIA. 111, 3, p. 522 1 p.

Research output: Contribution to journalArticle

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

Christophersen, I. E., Rienstra, M., Roselli, C., Yin, X., Geelhoed, B., Barnard, J., Lin, H., Arking, D. E., Smith, A. V., Albert, C. M., Chaffin, M., Tucker, N. R., Li, M., Klarin, D., Bihlmeyer, N. A., Low, S-K., Weeke, P. E., Müller-Nurasyid, M., Smith, J. G., Brody, J. A. & 31 others, Niemeijer, M. N., Dörr, M., Trompet, S., Huffman, J., Gustafsson, S., Schurmann, C., Kleber, M. E., Lyytikäinen, L-P., Seppälä, I., Malik, R., R V R Horimoto, A., Perez, M., Sinisalo, J., Aeschbacher, S., Thériault, S., Yao, J., Radmanesh, F., Weiss, S., Teumer, A., Choi, S. H., Weng, L-C., Clauss, S., Deo, R., Rader, D. J., Shah, S. H., Sun, A., Hopewell, J. C., Debette, S., Smith, B. H., Morris, A. P. & METASTROKE Consortium of the ISGC, Neurology Working Group of the CHARGE Consortium, 27 Jul 2017, In : Nature Genetics. 49, 8, p. 1286 1 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Estimating the burden of disease in chronic pain with and without neuropathic characteristics: does the choice between the EQ-5D and SF-6D matter?

Torrance, N., Lawson, K. D., Afolabi, E., Bennett, M. I., Serpell, M. G., Dunn, K. M. & Smith, B. H., Oct 2014, In : Pain. 155, 10, p. 1996-2004 9 p.

Research output: Contribution to journalArticle

Open Access
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33 Citations (Scopus)
256 Downloads (Pure)

Exome-wide association study of plasma lipids in >300,000 individuals

Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X-Y., Mahajan, A., Saleheen, D., Emdin, C., Alam, D. S., Alves, A. C., Amouyel, P., Di Angelantonio, E., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C. & 31 others, Boehnke, M., Boerwinkle, E., Bork-Jensen, J., Bottinger, E. P., Brandslund, I., Brown, M. J., Busonero, F., Caulfield, M. J., Chambers, J. C., Chasman, D. I., Chen, Y. E., Chen, Y-D. I., Chowdhury, R., Christensen, C., Chu, A. Y., Connell, J. M., Cucca, F., Cupples, L. A., Damrauer, S. M., Davies, G., Deary, I. J., Dedoussis, G., Denny, J. C., Dominiczak, A. F., Dubé, M. P., Ebeling, T., Eiriksdottir, G., Esko, T., Palmer, C. N. A., Smith, B. H. & Charge Diabetes Working Group, The EPIC-InterAct Consortium, EPIC-CVD Consortium, GOLD Consortium, VA Million Veteran Program, 30 Oct 2017, In : Nature Genetics. 49, 12, p. 1758-1766 9 p.

Research output: Contribution to journalLetter

Open Access
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162 Citations (Scopus)
160 Downloads (Pure)

Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants

Nagy, R., Boutin, T. S., Marten, J., Huffman, J. E., Kerr, S. M., Campbell, A., Evenden, L., Gibson, J., Amador, C., Howard, D. M., Navarro, P., Morris, A., Deary, I. J., Hocking, L. J., Padmanabhan, S., Smith, B. H., Joshi, P., Wilson, J. F., Hastie, N. D., Wright, A. F. & 5 others, McIntosh, A. M., Porteous, D. J., Haley, C. S., Vitart, V. & Hayward, C., 7 Mar 2017, In : Genome Medicine. 9, p. 1-14 14 p., 23.

Research output: Contribution to journalArticle

Open Access
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41 Citations (Scopus)
147 Downloads (Pure)
Open Access
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Genetic correlations between pain phenotypes and depression and neuroticism

Meng, W., Adams, M. J., Reel, P., Rajendrakumar, A., Huang, Y., Deary, I. J., Palmer, C. N. A., McIntosh, A. M. & Smith, B. H., Mar 2020, In : European Journal of Human Genetics. 28, p. 358-366 9 p.

Research output: Contribution to journalArticle

Open Access
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3 Citations (Scopus)
85 Downloads (Pure)

Genetic variation in hyperpolarization-activated cyclic nucleotide-gated channels and its relationship with neuroticism, cognition and risk of depression

McIntosh, A. M., Simen, A. A., Evans, K. L., Hall, J., MacIntyre, D. J., Blackwood, D., Morris, A. D., Smith, B. H., Dominiczak, A., Porteous, D., Deary, I. J. & Thomson, P. A., 2012, In : Frontiers in Genetics. 3, 00116.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Genome-wide association analysis identifies six new loci associated with forced vital capacity

Loth, D. W., Artigas, M. S., Gharib, S. A., Wain, L. V., Franceschini, N., Koch, B., Pottinger, T. D., Smith, A. V., Duan, Q., Oldmeadow, C., Lee, M. K., Strachan, D. P., James, A. L., Huffman, J. E., Vitart, V., Ramasamy, A., Wareham, N. J., Kaprio, J., Wang, X-Q., Trochet, H. & 31 others, Kähönen, M., Flexeder, C., Albrecht, E., Lopez, L. M., de Jong, K., Thyagarajan, B., Alves, A. C., Enroth, S., Omenaas, E., Joshi, P. K., Fall, T., Viñuela, A., Launer, L. J., Loehr, L. R., Fornage, M., Li, G., Wilk, J. B., Tang, W., Manichaikul, A., Lahousse, L., Harris, T. B., North, K. E., Rudnicka, A. R., Hui, J., Gu, X., Lumley, T., Wright, A. F., Hastie, N. D., Campbell, S., Generation Scotland & Smith, B. H., Jul 2014, In : Nature Genetics. 46, 7, p. 669-677 9 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Genome-wide association for major depression through age at onset stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

Power, R. A., Tansey, K. E., Buttenschøn, H. N., Cohen-Woods, S., Bigdeli, T., Hall, L. S., Kutalik, Z., Lee, S. H., Ripke, S., Steinberg, S., Teumer, A., Viktorin, A., Wray, N. R., Arolt, V., Baune, B. T., Boomsma, D. I., Børglum, A. D., Byrne, E. M., Castelao, E., Craddock, N. & 33 others, Craig, I. W., Dannlowski, U., Deary, I. J., Degenhardt, F., Forstner, A. J., Gordon, S. D., Grabe, H. J., Grove, J., Hamilton, S. P., Hayward, C., Heath, A. C., Hocking, L. J., Homuth, G., Hottenga, J. J., Kloiber, S., Krogh, J., Landén, M., Lang, M., Levinson, D. F., Lichtenstein, P., Lucae, S., MacIntyre, D. J., Madden, P., Magnusson, P. K. E., Martin, N. G., McIntosh, A. M., Middeldorp, C. M., Milaneschi, Y., Montgomery, G. W., Smith, B. H., CONVERGE Consortium, CARDIoGRAM Consortium & GERAD1 Consortium, 15 Feb 2017, In : Biological Psychiatry. 81, 4, p. 325-335 11 p.

Research output: Contribution to journalArticle

Open Access
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86 Citations (Scopus)
243 Downloads (Pure)

Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility

GenoMEL Consortium, Q-MEGA and QTWIN Investigators, ATHENS Melanoma Study Group, 23andMe, The SDH Study Group, IBD Investigators, Essen-Heidelberg Investigators, AMFS Investigators, MelaNostrum Consortium, Landi, M. T., Bishop, D. T., MacGregor, S., Machiela, M. J., Stratigos, A. J., Ghiorzo, P., Brossard, M., Calista, D., Choi, J., Fargnoli, M. C., Zhang, T. & 45 others, Rodolfo, M., Trower, A. J., Menin, C., Martinez, J., Hadjisavvas, A., Song, L., Stefanaki, I., Scolyer, R., Yang, R., Goldstein, A. M., Potrony, M., Kypreou, K. P., Pastorino, L., Queirolo, P., Pellegrini, C., Cattaneo, L., Zawistowski, M., Gimenez-Xavier, P., Rodriguez, A., Elefanti, L., Manoukian, S., Rivoltini, L., Smith, B. H., Loizidou, M. A., Del Regno, L., Massi, D., Mandala, M., Khosrotehrani, K., Akslen, L. A., Amos, C. I., Andresen, P. A., Avril, M-F., Azizi, E., Soyer, H. P., Bataille, V., Dalmasso, B., Bowdler, L. M., Burdon, K. P., Chen, W. V., Codd, V., Craig, J. E., Harris, J., Shi, J., Iles, M. M. & Law, M. H., May 2020, In : Nature Genetics. 52, 5, p. 494-504 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region

Peters, M. J., Broer, L., Willemen, H. L. D. M., Eiriksdottir, G., Hocking, L. J., Holliday, K. L., Horan, M. A., Meulenbelt, I., Neogi, T., Popham, M., Schmidt, C. O., Soni, A., Valdes, A. M., Amin, N., Dennison, E. M., Eijkelkamp, N., Harris, T. B., Hart, D. J., Hofman, A., Huygen, F. J. P. M. & 32 others, Jameson, K. A., Jones, G. T., Launer, L. J., Kerkhof, H. J. M., De Kruijf, M., McBeth, J., Kloppenburg, M., Ollier, W. E., Oostra, B., Payton, A., Rivadeneira, F., Smith, B. H., Smith, A. V., Stolk, L., Teumer, A., Thomson, W., Uitterlinden, A. G., Wang, K., Van Wingerden, S. H., Arden, N. K., Cooper, C., Felson, D., Gudnason, V., Macfarlane, G. J., Pendleton, N., Slagboom, P. E., Spector, T. D., Völzke, H., Kavelaars, A., Van Duijn, C. M., Williams, F. M. K. & Van Meurs, J. B. J., Mar 2013, In : Annals of the Rheumatic Diseases. 72, 3, p. 427-436 10 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Genome­-wide association study of alcohol consumption and genetic overlap with other health-­related traits in UK Biobank (=112,117)

Clarke, T. K., Adams, M. J., Davies, G., Howard, D. M., Hall, L. S., Padmanabhan, S., Smith, B. H., Hayward, C., Porteous, D. J., Deary, I. J. & McIntosh, A. M., Oct 2017, In : Molecular Psychiatry. 22, 10, p. 1376-1384 9 p.

Research output: Contribution to journalArticle

Open Access
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123 Citations (Scopus)
204 Downloads (Pure)

Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP

Wigmore, E. M., Hafferty, J. D., Hall, L. S., Howard, D. M., Clarke, T-K., Fabbri, C., Lewis, C. M., Uher, R., Navrady, L., Adams, M. J., Zeng, Y., Campbell, A., Gibson, J., Thomson, P. A., Hayward, C., Smith, B., Hocking, L. J., Padmanabhan, S., Deary, I. J., Porteous, D. J. & 4 others, Mors, O., Mattheisen, M., Nicodemus, K. K. & McIntosh, A. M., Apr 2020, In : Pharmacogenomics Journal. 20, p. 329-341 13 p.

Research output: Contribution to journalArticle

Open Access
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9 Citations (Scopus)
149 Downloads (Pure)

Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

Howard, D. M., Hall, L. S., Hafferty, J. D., Yanni, Z., Adams, M. J., Clarke, T-K., Porteous, D. J., Nagy, R., Hayward, C., Smith, B., Murray, A. D., Ryan, N. M., Evans, K. L., Haley, C. S., Deary, I. J., Thomson, P. A. & McIntosh, A. M., 30 Nov 2017, In : Translational Psychiatry. 7, p. 1-9 9 p., 1263.

Research output: Contribution to journalArticle

Open Access
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7 Citations (Scopus)
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Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., Shen, X., Gandin, I., McDaid, A. F., Hansen, T. F., Gordon, S. D., Giulianini, F., Boutin, T. S., Abdellaoui, A., Zhao, W., Medina-Gomez, C. & 93 others, Bartz, T. M., Trompet, S., Lange, L. A., Raffield, L., van der Spek, A., Galesloot, T. E., Proitsi, P., Yanek, L. R., Bielak, L. F., Payton, A., Murgia, F., Concas, M. P., Biino, G., Tajuddin, S. M., Seppälä, I., Amin, N., Boerwinkle, E., Børglum, A. D., Campbell, A., Demerath, E. W., Demuth, I., Faul, J. D., Ford, I., Gialluisi, A., Gögele, M., Graff, M., Hingorani, A. D., Hottenga, J. J., Hougaard, D. M., Hurme, M. A., Ikram, M. A., Jylhä, M., Kuh, D., Ligthart, L., Lill, C. M., Lindenberger, U., Lumley, T., Mägi, R., Marques-Vidal, P., Medland, S. E., Milani, L., Nagy, R., Ollier, W. E. R., Peyser, P. A., Pramstaller, P. P., Ridker, P. M., Rivadeneira, F., Ruggiero, D., Saba, Y., Schmidt, R., Schmidt, H., Slagboom, P. E., Smith, B. H., Smith, J. A., Sotoodehnia, N., Steinhagen-Thiessen, E., van Rooij, F. J. A., Verbeek, A. L., Vermeulen, S. H., Vollenweider, P., Wang, Y., Werge, T., Whitfield, J. B., Zonderman, A. B., Lehtimäki, T., Evans, M. K., Pirastu, M., Fuchsberger, C., Bertram, L., Pendleton, N., Kardia, S. L. R., Ciullo, M., Becker, D. M., Wong, A., Psaty, B. M., van Duijn, C. M., Wilson, J. G., Jukema, J. W., Kiemeney, L. A., Uitterlinden, A. G., Franceschini, N., North, K. E., Weir, D. R., Metspalu, A., Boomsma, D. I., Hayward, C., Chasman, D. I., Martin, N. G., Sattar, N., Campbell, H., Esko, T., Kutalik, Z. & Wilson, J. F., 13 Oct 2017, In : Nature Communications. 8, p. 1-13 13 p., 910.

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Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

Justice, A. E., Winkler, T. W., Feitosa, M. F., Graff, M., Fisher, V. A., Young, K. L., Barata, L., Deng, X., Czajkowski, J., Hadley, D., Ngwa, J. S., Ahluwalia, T. S., Chu, A. Y., Heard-Costa, N. L., Lim, E., Perez, J., Eicher, J. D., Kutalik, Z., Xue, L., Mahajan, A. & 297 others, Renström, F., Wu, J. M. W., Qi, Q., Ahmad, S., Alfred, T., Amin, N., Bielak, L. F., Bonnefond, A., Bragg-Gresham, J. L., Cadby, G., Chittani, M., Coggeshall, S., Corre, T., Direk, N., Eriksson, J., Fischer, K., Gorski, M., Neergaard Harder, M., Horikoshi, M., Huang, T., Huffman, J. E., Jackson, A. U., Justesen, J. M., Kanoni, S., Kinnunen, L., Kleber, M. E., Komulainen, P., Kumari, M., Lim, U., Luan, J., Lyytikäinen, L-P., Mangino, M., Manichaikul, A., Marten, J., Middelberg, R. P. S., Müller-Nurasyid, M., Navarro, P., Pérusse, L., Pervjakova, N., Sarti, C., Smith, A. V., Smith, J. A., Stančáková, A., Strawbridge, R. J., Stringham, H. M., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., van der Laan, S. W., van der Most, P. J., van Vliet-Ostaptchouk, J. V., Vedantam, S. L., Verweij, N., Vink, J. M., Vitart, V., Wu, Y., Yengo, L., Zhang, W., Hua Zhao, J., Zimmermann, M. E., Zubair, N., Abecasis, G. R., Adair, L. S., Afaq, S., Afzal, U., Bakker, S. J. L., Bartz, T. M., Beilby, J. P., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E. P., Braga, D., Buckley, B. M., Buyske, S., Campbell, H., Chambers, J. C., Collins, F. S., Curran, J. E., de Borst, G. J., de Craen, A. J. M., de Geus, E. J. C., Dedoussis, G., Delgado, G. E., den Ruijter, H. M., Eiriksdottir, G., Eriksson, A. L., Esko, T., Faul, J. D., Ford, I., Forrester, T., Gertow, K., Gigante, B., Glorioso, N., Gong, J., Grallert, H., Grammer, T. B., Grarup, N., Haitjema, S., Hallmans, G., Hamsten, A., Hansen, T., Harris, T. B., Hartman, C. A., Hassinen, M., Hastie, N. D., Heath, A. C., Hernandez, D., Hindorff, L. A., Hocking, L. J., Hollensted, M., Holmen, O. L., Homuth, G., Jan Hottenga, J., Huang, J., Hung, J., Hutri-Kähönen, N., Ingelsson, E., James, A. L., Jansson, J-O., Jarvelin, M-R., Jhun, M. A., Jørgensen, M. E., Juonala, M., Kähönen, M., Karlsson, M., Koistinen, H. A., Kolcic, I., Kolovou, G., Kooperberg, C., Krämer, B. K., Kuusisto, J., Kvaløy, K., Lakka, T. A., Langenberg, C., Launer, L. J., Leander, K., Lee, N. R., Lind, L., Lindgren, C. M., Linneberg, A., Lobbens, S., Loh, M., Lorentzon, M., Luben, R. N., Lubke, G., Ludolph-donislawski, A., Lupoli, S., Madden, P. A. F., Männikkö, R., Marques-Vidal, P., Martin, N. G., McKenzie, C. A., McKnight, B., Mellström, D., Menni, C., Montgomery, G. W., Musk, A. ., Narisu, N., Nauck, M., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Peyser, P. A., Pisinger, C., Porteous, D. J., Raitakari, O. T., Rankinen, T., Rao, D. C., Rasmussen-Torvik, L. J., Rawal, R., Rice, T. K., Ridker, P. M., Rose, L. M., Bien, S. A., Rudan, I., Sanna, S., Sarzynski, M. A., Sattar, N., Savonen, K., Schlessinger, D., Scholtens, S., Schurmann, C., Scott, R. A., Sennblad, B., Siemelink, M. A., Silbernagel, G., Slagboom, P. E., Snieder, H., Staessen, J. A., Stott, D. J., Swertz, M. A., Swift, A. J., Taylor, K. D., Tayo, B. O., Thorand, B., Thuillier, D., Tuomilehto, J., Uitterlinden, A. G., Vandenput, L., Vohl, M-C., Völzke, H., Vonk, J. M., Waeber, G., Waldenberger, M., Westendorp, R. G. J., Wild, S. H., Willemsen, G., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zhao, W., Zillikens, M. C., Baldassarre, D., Balkau, B., Bandinelli, S., Böger, C. A., Boomsma, D. I., Bouchard, C., Bruinenberg, M., Chasman, D. I., Chen, Y., Chines, P. S., Cooper, R. S., Cucca, F., Cusi, D., de Faire, U., Ferrucci, L., Franks, P. W., Froguel, P., Gordon-Larsen, P., Grabe, H-J., Gudnason, V., Haiman, C. A., Hayward, C., Hveem, K., Johnson, A. D., Wouter Jukema, J., Kardia, S. L. R., Kivimaki, M., Kooner, J. S., Kuh, D., Laakso, M., Lehtimäki, T., Marchand, L. L., März, W., McCarthy, M. I., Metspalu, A., Morris, A. P., Ohlsson, C., Palmer, L. J., Pasterkamp, G., Pedersen, O., Peters, A., Peters, U., Polasek, O., Psaty, B. M., Qi, L., Rauramaa, R., Smith, B. H., Sørensen, T. I. A., Strauch, K., Tiemeier, H., Tremoli, E., van der Harst, P., Vestergaard, H., Vollenweider, P., Wareham, N. J., Weir, D. R., Whitfield, J. B., Wilson, J. F., Tyrrell, J., Frayling, T. M., Barroso, I., Boehnke, M., Deloukas, P., Fox, C. S., Hirschhorn, J. N., Hunter, D. J., Spector, T. D., Strachan, D. P., van Duijn, C. M., Heid, I. M., Mohlke, K. L., Marchini, J. L., Loos, R. J. F., Kilpeläinen, T. O., Liu, C-T., Borecki, I. B., North, K. E. & Cupples, L. A., 26 Apr 2017, In : Nature Communications. 8, 19 p., 14977.

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Genome-wide physical activity interactions in adiposity: A meta-analysis of 200,452 adults

Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., Den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D. & 31 others, Hayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, J. M., Kleber, M. E., Hollensted, M., Lohman, K., Rivera, N. V., Whitfield, J. B., Zhao, J. H., Stringham, H. M., Lyytikäinen, L-P., Huppertz, C., Willemsen, G., Smith, B. H. & CHARGE Consortium, EPIC-InterAct Consortium, PAGE Consortium , 27 Apr 2017, In : PLoS Genetics. 13, 4, 26 p., e1006528.

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Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated with Major Depressive Disorder

Yanni, Z., Navarro, P., Shirali, M., Howard, D. M., Adams, M. J., Hall, L. S., Clarke, T-K., Thomson, P. A., Smith, B. H., Murray, A., Padmanabhan, S., Hayward, C., Boutin, T., MacIntyre, D. J., Lewis, C. M., Wray, N. R., Mehta, D., Penninx, B. W. J. H., Milaneschi, Y., Baune, B. T. & 20 others, Air, T., Hottenga, J-J., Mbarek, H., Castelao, E., Pistis, G., Schulze, T. G., Streit, F., Forstner, A. J., Byrne, E. M., Martin, N. G., Breen, G., Müller-Myhsok, B., Lucae, S., Kloiber, S., Domenici, E., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Deary, I. J., Porteous, D. J., Haley, C. S. & McIntosh, A. M., 1 Sep 2017, In : Biological Psychiatry. 82, 5, p. 312-321 10 p.

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Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK Biobank

Howard, D. M., Adams, M. J., Clarke, T-K., Wigmore, E. M., Zeng, Y., Hagenaars, S. P., Lyall, D. M., Thomson, P. A., Evans, K. L., Porteous, D. J., Nagy, R., Hayward, C., Haley, C. S., Smith, B. H., Murray, A. D., Batty, G. D., Deary, I. J. & McIntosh, A. M., 10 Aug 2017, In : Wellcome Open Research. 2, p. 1-13 13 p., 61.

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Heritability of chronic pain in 2195 extended families

Hocking, L. J., Morris, A. D., Dominiczak, A. F., Porteous, D. J., Smith, B. H. & Generation Scotland, Aug 2012, In : European Journal of Pain. 16, 7, p. 1053-1063 11 p.

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"I feel so stupid because I can't give a proper answer..." How older adults describe chronic pain: a qualitative study

Clarke, A., Anthony, G., Gray, D., Jones, D., McNamee, P., Schofield, P., Smith, B. H. & Martin, D., 2012, In : BMC Geriatrics. 12, 1, 78.

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Impact of sex and age on respiratory support and length of hospital stay among 1792 patients with COVID-19 in Wuhan, China

Zheng, H., Tan, J., Zhang, X., Luo, A., Wang, L., Zhu, W., Hebert, H. L., Meng, W., Smith, B. H., Colvin, L. A. & Hu, J., 1 Oct 2020, In : British Journal of Anaesthesia. 125, 4, p. E378-E380 3 p.

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Investigating shared aetiology between type 2 diabetes and major depressive disorder in a population based cohort

Clarke, T-K., Obsteter, J., Hall, L. S., Hayward, C., Thomson, P. A., Smith, B. H., Padmanabhan, S., Hocking, L. J., Deary, I. J., Porteous, D. J. & McIntosh, A. M., Apr 2017, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 174, 3, p. 227-234 8 p.

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