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  • Paul Davies
2019

CDK1 and CDK2 regulate NICD1 turnover and the periodicity of the segmentation clock

Carrieri, F., Murray, P., Ditsova, D., Ferris, M. A., Davies, P. & Dale, K., 1 Jul 2019, In : EMBO Reports. 20, 7, p. 1-22 22 p., e46436.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
136 Downloads (Pure)
2018

Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson’s disease kinase

Lis, P., Burel, S., Steger, M., Mann, M., Brown, F., Diez, F., Tonelli, F., Holton, J. L., Winglok Ho, P., Ho, S-L., Chou, M-Y., Polinski, N. K., Martinez, T. N., Davies, P. & Alessi, D. R., 2 Jan 2018, In : Biochemical Journal. 475, 1, p. 1-22 22 p.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
290 Downloads (Pure)

LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages

Härtlova, A., Herbst, S., Peltier, J., Rodgers, A., Bilkei-Gorzo, O., Fearns, A., Dill, B. D., Lee, H., Flynn, R., Cowley, S. A., Davies, P., Lewis, P. A., Ganley, I. G., Martinez, J., Alessi, D. R., Reith, A. D., Trost, M. & Gutierrez, M. G., 15 Jun 2018, In : The EMBO Journal. 37, 12, p. 1-17 17 p., e98694.

Research output: Contribution to journalArticle

Open Access
File
45 Citations (Scopus)
187 Downloads (Pure)
2016

Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain

Zhang, J., Gao, G., Begum, G., Wang, J., Khanna, A. R., Shmukler, B. E., Daubner, G. M., De Los Heros, P., Davies, P., Varghese, J., Bhuiyan, M. I. H., Duan, J., Zhang, J., Duran, D., Alper, S. L., Sun, D., Elledge, S. J., Alessi, D. R. & Kahle, K. T., 26 Oct 2016, In : Scientific Reports. 6, p. 1-19 19 p., 35986.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
147 Downloads (Pure)

Phosphoproteomics reveals that Parkinson’s disease kinase LRRK2 regulates a subset of Rab GTPases

Steger, M., Tonelli, F., Ito, G., Davies, P., Trost, M., Vetter, M., Wachter, S., Lorentzen, E., Duddy, G., Wilson, S., Baptista, M. A. S., Fiske, B. K., Fell, M. J., Morrow, J. A., Reith, A. D., Alessi, D. R. & Mann, M., 29 Jan 2016, In : eLife. 5, p. 1-28 28 p., e12813.

Research output: Contribution to journalArticle

Open Access
File
306 Citations (Scopus)
235 Downloads (Pure)
2013

Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies

Davies, P., Hinkle, K. M., Sukar, N. N., Sepulveda, B., Mesias, R., Serrano, G., Alessi, D. R., Beach, T. G., Benson, D. L., White, C. L., Cowell, R. M., Das, S. S., West, A. B. & Melrose, H. L., 1 Jul 2013, In : Biochemical Journal. 453, 1, p. 101-113 13 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)