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  • Julian Blow
2020

3.0 tera-basepairs as a fundamental limit for robust DNA replication

Al Mamun, M., Albergante, L., Blow, J. & Newman, T., 22 Apr 2020, In : Physical Biology.

Research output: Contribution to journalArticle

Open Access
File
25 Downloads (Pure)
2019

Defects in the origin licensing checkpoint stresses cells exiting G0

Blow, J. J., 1 Jul 2019, In : Journal of Cell Biology. 218, 7, p. 2080-2081 2 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
73 Downloads (Pure)
2018

Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing

Shoaib, M., Walter, D., Gillespie, P. J., Izard, F., Fahrenkrog, B., Lleres, D., Lerdrup, M., Johansen, J. V., Hansen, K., Julien, E., Blow, J. J. & Sørensen, C. S., 12 Sep 2018, In : Nature Communications. 9, 1, p. 1-11 11 p., 3704.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
113 Downloads (Pure)

Lgr5+ intestinal stem cells reside in an unlicensed G1 phase

Carroll, T., Newton, I., Chen, Y., Blow, J. & Nathke, I., 7 May 2018, In : Journal of Cell Biology. 217, 5, p. 1667-1685 19 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
155 Downloads (Pure)

The Anthelmintic Drug Niclosamide and Its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1

Barini, E., Miccoli, A., Tinarelli, F., Mulholland, K., Kadri, H., Khanim, F., Stojanovski, L., Read, K. D., Burness, K., Blow, J. J., Mehellou, Y. & Muqit, M. M. K., 2 Mar 2018, In : ChemBioChem. 19, 5, p. 425-429 5 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
147 Downloads (Pure)
2016

Cell cycle synchronization in xenopus egg extracts

Gillespie, P. J., Neusiedler, J., Creavin, K., Chadha, G. S. & Blow, J., 2016, Cell cycle oscillators: methods and protocols. Coutts, A. S. & Weston, L. (eds.). New York: Humana Press, p. 101-147 47 p. (Methods in Molecular Biology; vol. 1342).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

5 Citations (Scopus)

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

Galanos, P., Vougas, K., Walter, D., Polyzos, A., Maya-Mendoza, A., Haagensen, E. J., Kokkalis, A., Roumelioti, F-M., Gagos, S., Tzetis, M., Canovas, B., Igea, A., Ahuja, A. K., Zellweger, R., Havaki, S., Kanavakis, E., Kletsas, D., Roninson, I. B., Garbis, S. D., Lopes, M. & 7 others, Nebreda, A., Thanos, D., Blow, J. J., Townsend, P., Sørensen, C. S., Bartek, J. & Gorgoulis, V. G., Jul 2016, In : Nature Cell Biology. 18, 7, p. 777-789 13 p.

Research output: Contribution to journalArticle

Open Access
File
104 Citations (Scopus)
571 Downloads (Pure)

Direct non transcriptional role of NF-Y in DNA replication

Benatti, P., Belluti, S., Miotto, B., Neusiedler, J., Dolfini, D., Drac, M., Basile, V., Schwob, E., Mantovani, R., Blow, J. J. & Imbriano, C., 1 Apr 2016, In : Biochimica et Biophysica Acta. Molecular Cell Research. 1863, 4, p. 673-685 13 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
133 Downloads (Pure)

Inevitability and containment of replication errors for eukaryotic genome lengths spanning Megabase to Gigabase

Al Mamun, M., Albergante, L., Moreno, A., Carrington, J. T., Blow, J. & Newman, T. J., 27 Sep 2016, In : Proceedings of the National Academy of Sciences. 113, 39, p. E5765-E5774 10 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
432 Downloads (Pure)

The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability

Ho, T. L. F., Guilbaud, G., Blow, J. J., Sale, J. E. & Watson, C. J., 26 Apr 2016, In : Cell Reports. 15, 4, p. 724-734 11 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
141 Downloads (Pure)
Open Access
File
11 Citations (Scopus)
281 Downloads (Pure)

Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability

Lachaud, C., Moreno, A., Marchesi, F., Toth, R., Blow, J. J. & Rouse, J., 19 Feb 2016, In : Science. 351, 6275, p. 846-849 4 p.

Research output: Contribution to journalArticle

Open Access
58 Citations (Scopus)

Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells

Moreno, A., Carrington, J. T., Albergante, L., Al Mamun, M., Haagensen, E. J., Komseli, E-S., Gorgoulis, V. G., Newman, T. J. & Blow, J., 27 Sep 2016, In : Proceedings of the National Academy of Sciences. 113, 39, p. E5757-E5764 8 p.

Research output: Contribution to journalArticle

Open Access
File
45 Citations (Scopus)
353 Downloads (Pure)
Open Access
File
3 Citations (Scopus)
171 Downloads (Pure)

Xenopus Mcm10 is a CDK-substrate required for replication fork stability

Chadha, G. S., Gambus, A., Gillespie, P. J. & Blow, J., 2016, In : Cell Cycle. 15, 16, p. 2183-2195 13 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
221 Downloads (Pure)
2015

Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C.elegans Embryos

Sonneville, R., Craig, G., Labib, K., Gartner, A. & Blow, J. J., 21 Jul 2015, In : Cell Reports. 12, 3, p. 405-417 13 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
193 Downloads (Pure)
1 Citation (Scopus)
2014

Buffered Qualitative Stability explains the robustness and evolvability of transcriptional networks

Albergante, L., Blow, J. J. & Newman, T. J., 2 Sep 2014, In : eLife. 3, p. 1-28 28 p., e02863.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
167 Downloads (Pure)
Open Access
27 Citations (Scopus)

The contribution of dormant origins to genome stability: from cell biology to human genetics

Alver, R. C., Chadha, G. S. & Blow, J. J., Jul 2014, In : DNA Repair. 19, p. 182-189 8 p.

Research output: Contribution to journalArticle

Open Access
File
50 Citations (Scopus)
214 Downloads (Pure)

Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1

Poh, W. T., Chadha, G. S., Gillespie, P. J., Kaldis, P. & Blow, J. J., 8 Jan 2014, In : Open Biology. 4, January, 130138.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
133 Downloads (Pure)
2012

Dormant Origins, the Licensing Checkpoint, and the Response to Replicative Stresses

McIntosh, D. & Blow, J. J., Oct 2012, In : Cold spring harbor perspectives in biology. 4, 10, 10 p., 012955.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Dynamic interactions of high Cdt1 and geminin levels regulate S phase in early Xenopus embryos

Kisielewska, J. & Blow, J. J., 1 Jan 2012, In : Development. 139, 1, p. 63-74 12 p.

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)

Optimal Placement of Origins for DNA Replication

Karschau, J., Blow, J. J. & de Moura, A. P. S., 30 Jan 2012, In : Physical Review Letters. 108, 5, p. - 5 p., 058101.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Preparation and use of Xenopus egg extracts to study DNA replication and chromatin associated proteins

Gillespie, P. J., Gambus, A. & Blow, J. J., Jun 2012, In : Methods. 57, 2, p. 203-13 11 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Re-replication induced by geminin depletion occurs from G2 and is enhanced by checkpoint activation

Klotz-Noack, K., McIntosh, D., Schurch, N., Pratt, N. & Blow, J. J., 15 May 2012, In : Journal of Cell Science. 125, 10, p. 2436-2445 10 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

The dynamics of replication licensing in live Caenorhabditis elegans embryos

Sonneville, R., Querenet, M., Craig, A., Gartner, A. & Blow, J. J., 23 Jan 2012, In : Journal of Cell Biology. 196, 2, p. 233-246 14 p.

Research output: Contribution to journalArticle

Open Access
File
48 Citations (Scopus)
177 Downloads (Pure)