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  • Article

    Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

    UK IBD Genetics Consortium, Wellcome Trust Case Control Consortium 2, Barrett, J. C., Lee, J. C., Lees, C. W., Prescott, N. J., Anderson, C. A., Phillips, A., Wesley, E., Parnell, K., Zhang, H., Drummond, H., Nimmo, E. R., Massey, D., Blaszczyk, K., Elliott, T., Cotterill, L., Dallal, H., Lobo, A. J., Mowat, C. & 33 others, Sanderson, J. D., Jewell, D. P., Newman, W. G., Edwards, C., Ahmad, T., Mansfield, J. C., Satsangi, J., Parkes, M., Mathew, C. G., Donnelly, P., Peltonen, L., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Craddock, N., Deloukas, P., Duncanson, A., Jankowski, J., Markus, H. S., McCarthy, M. I., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S. J., Samani, N., Trembath, R. C., Viswanathan, A. C., Wood, N., Spencer, C. C. A., Bellenguez, C. & Wellcome Trust Case Control Consortium 2, Dec 2009, In: Nature Genetics. 41, 12, p. 1330-U99 7 p.

    Research output: Contribution to journalArticlepeer-review

    377 Citations (Scopus)
  • Genome-wide association study reveals the genetic complexity of fructan accumulation patterns in barley grain

    Matros, A., Houston, K., Tucker, M. R., Schreiber, M., Berger, B., Aubert, M. K., Wilkinson, L. G., Witzel, K., Waugh, R., Seiffert, U. & Burton, R. A., 29 Mar 2021, In: Journal of Experimental Botany. 72, 7, p. 2383-2402 20 p.

    Research output: Contribution to journalArticlepeer-review

    3 Citations (Scopus)
  • Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland

    Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Arnau-Soler, A., Macdonald-Dunlop, E., Adams, M. J., Clarke, T. K., MacIntyre, D. J., Milburn, K., Navrady, L., Hayward, C., McIntosh, A. M. & Thomson, P. A., 4 Feb 2019, In: Translational Psychiatry. 9, 1, p. 1-13 13 p., 14.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    39 Citations (Scopus)
    100 Downloads (Pure)
  • Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms

    Baurecht, H., Hotze, M., Brand, S., Büning, C., Cormican, P., Corvin, A., Ellinghaus, D., Ellinghaus, E., Esparza-Gordillo, J., Fölster-Holst, R., Franke, A., Gieger, C., Hubner, N., Illig, T., Irvine, A. D., Kabesch, M., Lee, Y. A. E., Lieb, W., Marenholz, I., McLean, W. H. I. & 19 others, Morris, D. W., Mrowietz, U., Nair, R., Nöthen, M. M., Novak, N., O'Regan, G. M., PAGE Consortium, Schreiber, S., Smith, C., Strauch, K., Stuart, P. E., Trembath, R., Tsoi, L. C., Weichenthal, M., Barker, J., Elder, J. T., Weidinger, S., Cordell, H. J. & Brown, S. J., 8 Jan 2015, In: American Journal of Human Genetics. 96, 1, p. 104-120 17 p.

    Research output: Contribution to journalArticlepeer-review

    93 Citations (Scopus)
  • Genome-wide Gene-by-Sex Interaction Studies Identify Novel Nonsyndromic Orofacial Clefts Risk Locus

    Awotoye, W., Comnick, C., Pendleton, C., Zeng, E., Alade, A., Mossey, P. A., Gowans, L. J. J., Eshete, M. A., Adeyemo, W. L., Naicker, T., Adeleke, C., Busch, T., Li, M., Petrin, A., Olotu, J., Hassan, M., Pape, J., Miller, S. E., Donkor, P., Anand, D. & 7 others, Lachke, S. A., Marazita, M. L., Adeyemo, A. A., Murray, J. C., Albokhari, D., Sobreira, N. & Butali, A., 23 Oct 2021, (E-pub ahead of print) In: Journal of Dental Research. 8 p., 220345211046614.

    Research output: Contribution to journalArticlepeer-review

  • Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

    Howard, D. M., Hall, L. S., Hafferty, J. D., Yanni, Z., Adams, M. J., Clarke, T-K., Porteous, D. J., Nagy, R., Hayward, C., Smith, B., Murray, A. D., Ryan, N. M., Evans, K. L., Haley, C. S., Deary, I. J., Thomson, P. A. & McIntosh, A. M., 30 Nov 2017, In: Translational Psychiatry. 7, p. 1-9 9 p., 1263.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    10 Citations (Scopus)
    139 Downloads (Pure)
  • Genome-wide identification of potato long intergenic noncoding RNAs responsive to Pectobacterium carotovorum subspecies brasiliense infection

    Kwenda, S., Birch, P. R. J. & Moleleki, L. N., 11 Aug 2016, In: BMC Genomics. 17, p. 1-14 14 p., 614.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    31 Citations (Scopus)
    156 Downloads (Pure)
  • Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

    Arnau-Soler, A., Adams, M. J., Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Hayward, C. & Thomson, P. A., 20 Dec 2018, In: PLoS ONE. 13, 12, e0209160.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    5 Citations (Scopus)
    116 Downloads (Pure)
  • Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci

    Ludwig, K. U., Mangold, E., Herms, S., Nowak, S., Reutter, H., Paul, A., Becker, J., Herberz, R., AlChawa, T., Nasser, E., Boehmer, A. C., Mattheisen, M., Alblas, M. A., Barth, S., Kluck, N., Lauster, C., Braumann, B., Reich, R. H., Hemprich, A., Poetzsch, S. & 19 others, Blaumeiser, B., Daratsianos, N., Kreusch, T., Murray, J. C., Marazita, M. L., Ruczinski, I., Scott, A. F., Beaty, T. H., Kramer, F-J., Wienker, T. F., Steegers-Theunissen, R. P., Rubini, M., Mossey, P. A., Hoffmann, P., Lange, C., Cichon, S., Propping, P., Knapp, M. & Noethen, M. M., Sep 2012, In: Nature Genetics. 44, 9, p. 968-971 4 p.

    Research output: Contribution to journalArticlepeer-review

    220 Citations (Scopus)
  • Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

    Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., Shen, X., Gandin, I., McDaid, A. F., Hansen, T. F., Gordon, S. D., Giulianini, F., Boutin, T. S., Abdellaoui, A., Zhao, W., Medina-Gomez, C. & 93 others, Bartz, T. M., Trompet, S., Lange, L. A., Raffield, L., van der Spek, A., Galesloot, T. E., Proitsi, P., Yanek, L. R., Bielak, L. F., Payton, A., Murgia, F., Concas, M. P., Biino, G., Tajuddin, S. M., Seppälä, I., Amin, N., Boerwinkle, E., Børglum, A. D., Campbell, A., Demerath, E. W., Demuth, I., Faul, J. D., Ford, I., Gialluisi, A., Gögele, M., Graff, M., Hingorani, A. D., Hottenga, J. J., Hougaard, D. M., Hurme, M. A., Ikram, M. A., Jylhä, M., Kuh, D., Ligthart, L., Lill, C. M., Lindenberger, U., Lumley, T., Mägi, R., Marques-Vidal, P., Medland, S. E., Milani, L., Nagy, R., Ollier, W. E. R., Peyser, P. A., Pramstaller, P. P., Ridker, P. M., Rivadeneira, F., Ruggiero, D., Saba, Y., Schmidt, R., Schmidt, H., Slagboom, P. E., Smith, B. H., Smith, J. A., Sotoodehnia, N., Steinhagen-Thiessen, E., van Rooij, F. J. A., Verbeek, A. L., Vermeulen, S. H., Vollenweider, P., Wang, Y., Werge, T., Whitfield, J. B., Zonderman, A. B., Lehtimäki, T., Evans, M. K., Pirastu, M., Fuchsberger, C., Bertram, L., Pendleton, N., Kardia, S. L. R., Ciullo, M., Becker, D. M., Wong, A., Psaty, B. M., van Duijn, C. M., Wilson, J. G., Jukema, J. W., Kiemeney, L. A., Uitterlinden, A. G., Franceschini, N., North, K. E., Weir, D. R., Metspalu, A., Boomsma, D. I., Hayward, C., Chasman, D. I., Martin, N. G., Sattar, N., Campbell, H., Esko, T., Kutalik, Z. & Wilson, J. F., 13 Oct 2017, In: Nature Communications. 8, p. 1-13 13 p., 910.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    66 Citations (Scopus)
    133 Downloads (Pure)
  • Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

    Berndt, S. I., Gustafsson, S., Maegi, R., Ganna, A., Wheeler, E., Feitosa, M. F., Justice, A. E., Monda, K. L., Croteau-Chonka, D. C., Day, F. R., Esko, T., Fall, T., Ferreira, T., Gentilini, D., Jackson, A. U., Luan, J., Randall, J. C., Vedantam, S., Willer, C. J., Winkler, T. W. & 302 others, Wood, A. R., Workalemahu, T., Hu, Y-J., Lee, S. H., Liang, L., Lin, D-Y., Min, J. L., Neale, B. M., Thorleifsson, G., Yang, J., Albrecht, E., Amin, N., Bragg-Gresham, J. L., Cadby, G., den Heijer, M., Eklund, N., Fischer, K., Goel, A., Hottenga, J-J., Huffman, J. E., Jarick, I., Johansson, A., Johnson, T., Kanoni, S., Kleber, M. E., Koenig, I. R., Kristiansson, K., Kutalik, Z., Lamina, C., Lecoeur, C., Li, G., Mangino, M., McArdle, W. L., Medina-Gomez, C., Mueller-Nurasyid, M., Ngwa, J. S., Nolte, I. M., Paternoster, L., Pechlivanis, S., Perola, M., Peters, M. J., Preuss, M., Rose, L. M., Shi, J., Shungin, D., Smith, A. V., Strawbridge, R. J., Surakka, I., Teumer, A., Trip, M. D., Tyrer, J., Van Vliet-Ostaptchouk, J. V., Vandenput, L., Waite, L. L., Zhao, J. H., Absher, D., Asselbergs, F. W., Atalay, M., Attwood, A. P., Balmforth, A. J., Basart, H., Beilby, J., Bonnycastle, L. L., Brambilla, P., Bruinenberg, M., Campbell, H., Chasman, D. I., Chines, P. S., Collins, F. S., Connell, J. M., Cookson, W. O., de Faire, U., de Vegt, F., Dei, M., Dimitriou, M., Edkins, S., Estrada, K., Evans, D. M., Farrall, M., Ferrario, M. M., Ferrieres, J., Franke, L., Frau, F., Gejman, P. V., Grallert, H., Groenberg, H., Gudnason, V., Hall, A. S., Hall, P., Hartikainen, A-L., Hayward, C., Heard-Costa, N. L., Heath, A. C., Hebebrand, J., Homuth, G., Hu, F. B., Hunt, S. E., Hyppoenen, E., Iribarren, C., Jacobs, K. B., Jansson, J-O., Jula, A., Kahonen, M., Kathiresan, S., Kee, F., Khaw, K-T., Kivimaki, M., König, W., Kraja, A. T., Kumari, M., Kuulasmaa, K., Kuusisto, J., Laitinen, J. H., Lakka, T. A., Langenberg, C., Launer, L. J., Lind, L., Lindstrom, J., Liu, J., Liuzzi, A., Lokki, M-L., Lorentzon, M., Madden, P. A., Magnusson, P. K., Manunta, P., Marek, D., Maerz, W., Leach, I. M., McKnight, B., Medland, S. E., Mihailov, E., Milani, L., Montgomery, G. W., Mooser, V., Mühleisen, T. W., Munroe, P. B., Musk, A. W., Narisu, N., Navis, G., Nicholson, G., Nohr, E. A., Ong, K. K., Oostra, B. A., Palmer, C. N. A., Palotie, A., Peden, J. F., Pedersen, N., Peters, A., Polasek, O., Pouta, A., Pramstaller, P. P., Prokopenko, I., Puetter, C., Radhakrishnan, A., Raitakari, O., Rendon, A., Rivadeneira, F., Rudan, I., Saaristo, T. E., Sambrook, J. G., Sanders, A. R., Sanna, S., Saramies, J., Schipf, S., Schreiber, S., Schunkert, H., Shin, S-Y., Signorini, S., Sinisalo, J., Skrobek, B., Soranzo, N., Stancakova, A., Stark, K., Stephens, J. C., Stirrups, K., Stolk, R. P., Stumvoll, M., Swift, A. J., Theodoraki, E. V., Thorand, B., Tregouet, D-A., Tremoli, E., Van der Klauw, M. M., van Meurs, J. B. J., Vermeulen, S. H., Viikari, J., Virtamo, J., Vitart, V., Waeber, G., Wang, Z., Widen, E., Wild, S. H., Willemsen, G., Winkelmann, B. R., Witteman, J. C. M., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zillikens, M. C., Amouyel, P., Boehm, B. O., Boerwinkle, E., Boomsma, D. I., Caulfield, M. J., Chanock, S. J., Cupples, L. A., Cusi, D., Dedoussis, G. V., Erdmann, J., Eriksson, J. G., Franks, P. W., Froguel, P., Gieger, C., Gyllensten, U., Hamsten, A., Harris, T. B., Hengstenberg, C., Hicks, A. A., Hingorani, A., Hinney, A., Hofman, A., Hovingh, K. G., Hveem, K., Illig, T., Jarvelin, M-R., Jöckel, K-H., Keinanen-Kiukaanniemi, S. M., Kiemeney, L. A., Kuh, D., Laakso, M., Lehtimaki, T., Levinson, D. F., Martin, N. G., Metspalu, A., Morris, A. D., Nieminen, M. S., Njolstad, I., Ohlsson, C., Oldehinkel, A. J., Ouwehand, W. H., Palmer, L. J., Penninx, B., Power, C., Province, M. A., Psaty, B. M., Qi, L., Rauramaa, R., Ridker, P. M., Ripatti, S., Salomaa, V., Samani, N. J., Snieder, H., Sorensen, T. I. A., Spector, T. D., Stefansson, K., Tonjes, A., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., van der Harst, P., Vollenweider, P., Wallaschofski, H., Wareham, N. J., Watkins, H., Wichmann, H-E., Wilson, J. F., Abecasis, G. R., Assimes, T. L., Barroso, I., Boehnke, M., Borecki, I. B., Deloukas, P., Fox, C. S., Frayling, T., Groop, L. C., Haritunian, T., Heid, I. M., Hunter, D., Kaplan, R. C., Karpe, F., Moffatt, M. F., Mohlke, K. L., O'Connell, J. R., Pawitan, Y., Schadt, E. E., Schlessinger, D., Steinthorsdottir, V., Strachan, D. P., Thorsteinsdottir, U., van Duijn, C. M., Visscher, P. M., Di Blasio, A. M., Hirschhorn, J. N., Lindgren, C. M., Morris, A. P., Meyre, D., Scherag, A., McCarthy, M. I., Speliotes, E. K., North, K. E., Loos, R. J. F. & Ingelsson, E., May 2013, In: Nature Genetics. 45, 5, p. 501-512 12 p.

    Research output: Contribution to journalArticlepeer-review

    381 Citations (Scopus)
  • Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

    NEIGHBORHOOD Consortium, ANZRAG Consortium, BioBank Japan Project, UK Biobank Eye and Vision Consortium, Gharahkhani, P., Jorgenson, E., Hysi, P., Khawaja, A. P., Pendergrass, S., Han, X., Ong, J. S., Hewitt, A. W., Segrè, A. V., Rouhana, J. M., Hamel, A. R., Igo, R. P., Choquet, H., Qassim, A., Josyula, N. S., Cooke Bailey, J. N. & 63 others, Bonnemaijer, P. W. M., Iglesias, A., Siggs, O. M., Young, T. L., Vitart, V., Thiadens, A. A. H. J., Karjalainen, J., Uebe, S., Melles, R. B., Nair, K. S., Luben, R., Simcoe, M., Amersinghe, N., Cree, A. J., Hohn, R., Poplawski, A., Chen, L. J., Rong, S. S., Aung, T., Vithana, E. N., Tamiya, G., Shiga, Y., Yamamoto, M., Nakazawa, T., Currant, H., Birney, E., Wang, X., Auton, A., Lupton, M. K., Martin, N. G., Ashaye, A., Olawoye, O., Williams, S. E., Akafo, S., Ramsay, M., Hashimoto, K., Kamatani, Y., Akiyama, M., Momozawa, Y., Foster, P. J., Khaw, P. T., Morgan, J. E., Strouthidis, N. G., Kraft, P., Kang, J. H., Pang, C. P., Pasutto, F., Mitchell, P., Lotery, A. J., Palotie, A., van Duijn, C. M., Haines, J. L., Hammond, C., Pasquale, L. R., Klaver, C. C. W., Hauser, M., Khor, C-C., Mackey, D. A., Kubo, M., Cheng, C-Y., Craig, J. E., MacGregor, S. & Wiggs, J. L., 24 Feb 2021, In: Nature Communications. 12, 16 p., 1258.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    16 Citations (Scopus)
    24 Downloads (Pure)
  • Genome-wide meta-analysis identifies genetic variants associated with glycemic response to sulfonylureas

    Dawed, A. Y., Yee, S. W., Zhou, K., van Leeuwen, N., Zhang, Y., Siddiqui, M. K., Etheridge, A., Innocenti, F., Xu, F., Li, J. H., Beulens, J. W., van der Heijden, A. A., Slieker, R. C., Chang, Y-C., Mercader, J. M., Kaur, V., Witte, J. S., Lee, M. T. M., Kamatani, Y., Momozawa, Y. & 7 others, Kubo, M., Palmer, C. N. A., Florez, J. C., Hedderson, M. M., 't Hart, L. M., Giacomini, K. M. & Pearson, E. R., 30 Sep 2021, In: Diabetes Care. 44, 9, dc211152.

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  • Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne

    The Acne Genetic Study Group, 1 Dec 2018, In: Nature Communications. 9, 1, 8 p., 5075.

    Research output: Contribution to journalArticlepeer-review

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    15 Citations (Scopus)
    96 Downloads (Pure)
  • Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain

    Suri, P., Palmer, M. R., Tsepilov, Y. A., Freidin, M. B., Boer, C. G., Yau, M. S., Evans, D. S., Gelemanovic, A., Bartz, T. M., Nethander, M., Arbeeva, L., Karssen, L., Neogi, T., Campbell, A., Mellstrom, D., Ohlsson, C., Marshall, L. M., Orwoll, E., Uitterlinden, A., Rotter, J. I. & 17 others, Lauc, G., Psaty, B. M., Karlsson, M. K., Lane, N. E., Jarvik, G. P., Polasek, O., Hochberg, M., Jordan, J. M., Van Meurs, J. B. J., Jackson, R., Nielson, C. M., Mitchell, B. D., Smith, B. H., Hayward, C., Smith, N. L., Aulchenko, Y. S. & Williams, F. M. K., 27 Sep 2018, In: PLoS Genetics. 14, 9, p. 1-23 23 p., e1007601.

    Research output: Contribution to journalArticlepeer-review

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    33 Citations (Scopus)
    105 Downloads (Pure)
  • Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

    Justice, A. E., Winkler, T. W., Feitosa, M. F., Graff, M., Fisher, V. A., Young, K. L., Barata, L., Deng, X., Czajkowski, J., Hadley, D., Ngwa, J. S., Ahluwalia, T. S., Chu, A. Y., Heard-Costa, N. L., Lim, E., Perez, J., Eicher, J. D., Kutalik, Z., Xue, L., Mahajan, A. & 297 others, Renström, F., Wu, J. M. W., Qi, Q., Ahmad, S., Alfred, T., Amin, N., Bielak, L. F., Bonnefond, A., Bragg-Gresham, J. L., Cadby, G., Chittani, M., Coggeshall, S., Corre, T., Direk, N., Eriksson, J., Fischer, K., Gorski, M., Neergaard Harder, M., Horikoshi, M., Huang, T., Huffman, J. E., Jackson, A. U., Justesen, J. M., Kanoni, S., Kinnunen, L., Kleber, M. E., Komulainen, P., Kumari, M., Lim, U., Luan, J., Lyytikäinen, L-P., Mangino, M., Manichaikul, A., Marten, J., Middelberg, R. P. S., Müller-Nurasyid, M., Navarro, P., Pérusse, L., Pervjakova, N., Sarti, C., Smith, A. V., Smith, J. A., Stančáková, A., Strawbridge, R. J., Stringham, H. M., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., van der Laan, S. W., van der Most, P. J., van Vliet-Ostaptchouk, J. V., Vedantam, S. L., Verweij, N., Vink, J. M., Vitart, V., Wu, Y., Yengo, L., Zhang, W., Hua Zhao, J., Zimmermann, M. E., Zubair, N., Abecasis, G. R., Adair, L. S., Afaq, S., Afzal, U., Bakker, S. J. L., Bartz, T. M., Beilby, J. P., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E. P., Braga, D., Buckley, B. M., Buyske, S., Campbell, H., Chambers, J. C., Collins, F. S., Curran, J. E., de Borst, G. J., de Craen, A. J. M., de Geus, E. J. C., Dedoussis, G., Delgado, G. E., den Ruijter, H. M., Eiriksdottir, G., Eriksson, A. L., Esko, T., Faul, J. D., Ford, I., Forrester, T., Gertow, K., Gigante, B., Glorioso, N., Gong, J., Grallert, H., Grammer, T. B., Grarup, N., Haitjema, S., Hallmans, G., Hamsten, A., Hansen, T., Harris, T. B., Hartman, C. A., Hassinen, M., Hastie, N. D., Heath, A. C., Hernandez, D., Hindorff, L. A., Hocking, L. J., Hollensted, M., Holmen, O. L., Homuth, G., Jan Hottenga, J., Huang, J., Hung, J., Hutri-Kähönen, N., Ingelsson, E., James, A. L., Jansson, J-O., Jarvelin, M-R., Jhun, M. A., Jørgensen, M. E., Juonala, M., Kähönen, M., Karlsson, M., Koistinen, H. A., Kolcic, I., Kolovou, G., Kooperberg, C., Krämer, B. K., Kuusisto, J., Kvaløy, K., Lakka, T. A., Langenberg, C., Launer, L. J., Leander, K., Lee, N. R., Lind, L., Lindgren, C. M., Linneberg, A., Lobbens, S., Loh, M., Lorentzon, M., Luben, R. N., Lubke, G., Ludolph-donislawski, A., Lupoli, S., Madden, P. A. F., Männikkö, R., Marques-Vidal, P., Martin, N. G., McKenzie, C. A., McKnight, B., Mellström, D., Menni, C., Montgomery, G. W., Musk, A. ., Narisu, N., Nauck, M., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Peyser, P. A., Pisinger, C., Porteous, D. J., Raitakari, O. T., Rankinen, T., Rao, D. C., Rasmussen-Torvik, L. J., Rawal, R., Rice, T. K., Ridker, P. M., Rose, L. M., Bien, S. A., Rudan, I., Sanna, S., Sarzynski, M. A., Sattar, N., Savonen, K., Schlessinger, D., Scholtens, S., Schurmann, C., Scott, R. A., Sennblad, B., Siemelink, M. A., Silbernagel, G., Slagboom, P. E., Snieder, H., Staessen, J. A., Stott, D. J., Swertz, M. A., Swift, A. J., Taylor, K. D., Tayo, B. O., Thorand, B., Thuillier, D., Tuomilehto, J., Uitterlinden, A. G., Vandenput, L., Vohl, M-C., Völzke, H., Vonk, J. M., Waeber, G., Waldenberger, M., Westendorp, R. G. J., Wild, S. H., Willemsen, G., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zhao, W., Zillikens, M. C., Baldassarre, D., Balkau, B., Bandinelli, S., Böger, C. A., Boomsma, D. I., Bouchard, C., Bruinenberg, M., Chasman, D. I., Chen, Y., Chines, P. S., Cooper, R. S., Cucca, F., Cusi, D., de Faire, U., Ferrucci, L., Franks, P. W., Froguel, P., Gordon-Larsen, P., Grabe, H-J., Gudnason, V., Haiman, C. A., Hayward, C., Hveem, K., Johnson, A. D., Wouter Jukema, J., Kardia, S. L. R., Kivimaki, M., Kooner, J. S., Kuh, D., Laakso, M., Lehtimäki, T., Marchand, L. L., März, W., McCarthy, M. I., Metspalu, A., Morris, A. P., Ohlsson, C., Palmer, L. J., Pasterkamp, G., Pedersen, O., Peters, A., Peters, U., Polasek, O., Psaty, B. M., Qi, L., Rauramaa, R., Smith, B. H., Sørensen, T. I. A., Strauch, K., Tiemeier, H., Tremoli, E., van der Harst, P., Vestergaard, H., Vollenweider, P., Wareham, N. J., Weir, D. R., Whitfield, J. B., Wilson, J. F., Tyrrell, J., Frayling, T. M., Barroso, I., Boehnke, M., Deloukas, P., Fox, C. S., Hirschhorn, J. N., Hunter, D. J., Spector, T. D., Strachan, D. P., van Duijn, C. M., Heid, I. M., Mohlke, K. L., Marchini, J. L., Loos, R. J. F., Kilpeläinen, T. O., Liu, C-T., Borecki, I. B., North, K. E. & Cupples, L. A., 26 Apr 2017, In: Nature Communications. 8, 19 p., 14977.

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  • Genome-wide physical activity interactions in adiposity: A meta-analysis of 200,452 adults

    Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., Den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D. & 31 others, Hayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, J. M., Kleber, M. E., Hollensted, M., Lohman, K., Rivera, N. V., Whitfield, J. B., Zhao, J. H., Stringham, H. M., Lyytikäinen, L-P., Huppertz, C., Willemsen, G., Smith, B. H. & CHARGE Consortium, EPIC-InterAct Consortium, PAGE Consortium , 27 Apr 2017, In: PLoS Genetics. 13, 4, 26 p., e1006528.

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  • Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated with Major Depressive Disorder

    Yanni, Z., Navarro, P., Shirali, M., Howard, D. M., Adams, M. J., Hall, L. S., Clarke, T-K., Thomson, P. A., Smith, B. H., Murray, A., Padmanabhan, S., Hayward, C., Boutin, T., MacIntyre, D. J., Lewis, C. M., Wray, N. R., Mehta, D., Penninx, B. W. J. H., Milaneschi, Y., Baune, B. T. & 20 others, Air, T., Hottenga, J-J., Mbarek, H., Castelao, E., Pistis, G., Schulze, T. G., Streit, F., Forstner, A. J., Byrne, E. M., Martin, N. G., Breen, G., Müller-Myhsok, B., Lucae, S., Kloiber, S., Domenici, E., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Deary, I. J., Porteous, D. J., Haley, C. S. & McIntosh, A. M., 1 Sep 2017, In: Biological Psychiatry. 82, 5, p. 312-321 10 p.

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  • Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6

    Baker, N., Alsford, S. & Horn, D., 2011, In: Molecular and Biochemical Parasitology. 176, 1, p. 55-57 3 p.

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    91 Citations (Scopus)
  • Genome-wide RNAi selection identifies a regulator of transmission stage-enriched gene families and cell-type differentiation in Trypanosoma brucei

    Rico, E., Ivens, A., Glover, L., Horn, D. & Matthews, K. R., 23 Mar 2017, In: PLoS Pathogens. 13, 3, p. 1-25 25 p., e1006279.

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  • Genome-Wide Scan for Parent-of-Origin Effects in a sub-Saharan African Cohort With Nonsyndromic Cleft Lip and/or Cleft Palate (CL/P)

    Gowans, L. J. J., Comnick, C. L., Mossey, P. A., Eshete, M. A., Adeyemo, W. L., Naicker, T., Awotoye, W. A., Petrin, A., Adeleke, C., Donkor, P., Busch, T. D., James, O., Ogunlewe, M. O., Li, M., Olotu, J., Hassan, M., Adeniyan, O. A., Obiri-Yeboah, S., Arthur, F. K. N., Agbenorku, P. & 9 others, Oti, A. A., Olatosi, O., Adamson, O. O., Fashina, A. A., Zeng, E., Marazita, M. L., Adeyemo, A. A., Murray, J. C. & Butali, A., 12 Aug 2021, (E-pub ahead of print) In: Cleft Palate-Craniofacial Journal. 11 p.

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  • Genomewide single nucleotide polymorphism microarray mapping in basal cell carcinomas unveils uniparental disomy as a key somatic event

    Teh, M-T., Blaydon, D., Chaplin, T., Foot, N. J., Skoulakis, S., Raghavan, M., Harwood, C. A., Proby, C. M., Philpott, M. P., Young, B. D. & Kelsell, D. P., Oct 2005, In: Cancer Research. 65, 19, p. 8597-8603 7 p.

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    125 Citations (Scopus)
  • Genome-wide SNP discovery and linkage analysis in barley based on genes responsive to abiotic stress

    Rostoks, N., Mudie, S., Cardle, L., Russell, J., Ramsay, L., Booth, A., Svensson, J. T., Wanamaker, S. I., Walia, H., Rodriguez, E. M., Hedley, P. E., Liu, H., Morris, J., Close, T. J., Marshall, D. F. & Waugh, R., 1 Dec 2005, In: Molecular Genetics and Genomics. 274, 5, p. 515-527 13 p.

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    225 Citations (Scopus)
  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

    DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Mahajan, A., Go, M. J., Zhang, W., Below, J. E., Gaulton, K. J., Ferreira, T., Horikoshi, M., Johnson, A. D., Ng, M. C. Y., Prokopenko, I., Saleheen, D., Wang, X., Zeggini, E., Abecasis, G. R., Adair, L. S., Almgren, P., Atalay, M., Aung, T., Baldassarre, D. & 30 others, Balkau, B., Bao, Y., Barnett, A. H., Barroso, I., Basit, A., Been, L. F., Beilby, J., Bell, G. I., Benediktsson, R., Bergman, R. N., OBoehm, B., Boerwinkle, E., Bonnycastle, L. L., Burtt, N., Cai, Q., Campbell, H., Carey, J., Cauchi, S., Caulfield, M., Doney, A. S. F., Donnelly, P. J., James, A., Matthews, D. R., Morris, A. D., Palmer, C. N. A., Scott, J., Scott, L. J., Shah, N., Wood, A. R. & Zhang, F., 9 Feb 2014, In: Nature Genetics. 46, 3, p. 234-244 11 p.

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    676 Citations (Scopus)
  • Genomic analyses in african populations identify novel risk loci for cleft palate

    Butali, A., Mossey, P. A., Adeyemo, W. L., Eshete, M. A., Gowans, L. J. J., Busch, T. D., Jain, D., Yu, W., Huan, L., Laurie, C. A., Laurie, C. C., Nelson, S., Li, M., Sanchez-Lara, P. A., Magee, W. P., Magee, K. S., Auslander, A., Brindopke, F., Kay, D. M., Caggana, M. & 51 others, Romitti, P. A., Mills, J. L., Audu, R., Onwuamah, C., Oseni, G. O., Owais, A., James, O., Olaitan, P. B., Aregbesola, B. S., Braimah, R. O., Oginni, F. O., Oladele, A. O., Bello, S. A., Rhodes, J., Shiang, R., Donkor, P., Obiri-Yeboah, S., Arthur, F. K. N., Twumasi, P., Agbenorku, P., Plange-Rhule, G., Oti, A. A., Ogunlewe, O. M., Oladega, A. A., Adekunle, A. A., Erinoso, A. O., Adamson, O. O., Elufowoju, A. A., Ayelomi, O. I., Hailu, T., Hailu, A., Demissie, Y., Derebew, M., Eliason, S., Romero-Bustillous, M., Lo, C., Park, J., Desai, S., Mohammed, M., Abate, F., Abdur-Rahman, L. O., Anand, D., Saadi, I., Oladugba, A. V., Lachke, S. A., Amendt, B. A., Rotimi, C. N., Marazita, M. L., Cornell, R. A., Murray, J. C. & Adeyemo, A. A., 15 Mar 2019, In: Human Molecular Genetics. 28, 6, p. 1038-1051 14 p.

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  • Genomic analysis of atypical fibroxanthoma

    Lai, K., Harwood, C. A., Purdie, K. J., Proby, C. M., Leigh, I. M., Ravi, N., Mully, T. W., Brooks, L., Sandoval, P. M., Rosenblum, M. D. & Arron, S. T., 15 Nov 2017, In: PLoS ONE. 12, 11, p. 1-15 15 p., e0188272.

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  • Genomic and Proteomic Studies on the Mode of Action of Oxaboroles against the African Trypanosome

    Jones, D. C., Foth, B. J., Urbaniak, M. D., Patterson, S., Ong, H. B., Berriman, M. & Fairlamb, A. H., 18 Dec 2015, In: PLoS Neglected Tropical Diseases. 9, 12, e0004299.

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  • Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk

    Brænne, I., Zeng, L., Willenborg, C., Tragante, V., Kessler, T., Willer, C. J., Laakso, M., Wallentin, L., Franks, P. W., Salomaa, V., Dehghan, A., Meitinger, T., Samani, N. J., Asselbergs, F. W., Erdmann, J., Schunkert, H., Deloukas, P., Kanoni, S., Willenborg, C., Farrall, M. & 34 others, Assimes, T. L., Thompson, J. R., Ingelsson, E., Saleheen, D., Erdmann, J., Goldstein, B. A., Stirrups, K., König, I. R., Cazier, J-B., Johansson, Å., Hall, A. S., Lee, J-Y., Willer, C. J., Chambers, J. C., Esko, T., Folkersen, L., Goel, A., Grundberg, E., Havulinna, A. S., Ho, W. K., Hopewell, J. C., Eriksson, N., Kleber, M. E., Kristiansson, K., Lundmark, P., Lyytikäinen, L-P., Doney, A. S. F., Morris, A. D., Kim, H. S., Palmer, C. N. A., CARDIoGRAM Consortium, CARDIoGRAMplusC4D Consortium, MuTHER Consortium & Wellcome Trust Case Control Consortium, 22 Aug 2017, In: PLoS ONE. 12, 8, p. 1-19 19 p., e0182999.

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  • Genomic Differences between Listeria monocytogenes EGDe Isolates Reveal Crucial Roles for SigB and Wall Rhamnosylation in Biofilm Formation

    Hsu, C-Y., Cairns, L., Hobley, L., Abbott, J., O'Byrne, C. & Stanley-Wall, N. R., 11 Mar 2020, In: Journal of Bacteriology. 202, 7, 13 p., e00692-19.

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  • Genomic Diversity of Pigeon Pea (Cajanus cajan L. Millsp.) Endosymbionts in India and Selection of Potential Strains for Use as Agricultural Inoculants

    Jorrin, B., Maluk, M., Atoliya, N., Kumar, S. C., Chalasani, D., Tkacz, A., Singh, P., Basu, A., Pullabhotla, S. V., Kumar, M., Mohanty, S. R., East, A. K., Ramachandran, V. K., James, E. K., Podile, A. R., Saxena, A. K., Rao, DLN. & Poole, P. S., 7 Sep 2021, In: Frontiers in Plant Science. 12, 19 p., 680981.

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  • Genomic editing of metformin efficacy-associated genetic variants in SLC47A1 does not alter SLC47A1 expression

    Kalamajski, S., Huang, M., Dalla-Riva, J., Keller, M., Dawed, A. Y., Hansson, O., Pearson, E. R., Mulder, H. & Franks, P. W., 9 Sep 2021, In: Human Molecular Genetics.

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  • Genomic epidemiology reveals multiple introductions of SARS-CoV-2 from mainland Europe into Scotland

    da Silva Filipe, A., Shepherd, J. G., Williams, T., Hughes, J., Aranday-Cortes, E., Asamaphan, P., Ashraf, S., Balcazar, C., Brunker, K., Campbell, A., Carmichael, S., Davis, C., Dewar, R., Gallagher, M. D., Gunson, R., Hill, V., Ho, A., Jackson, B., James, E., Jesudason, N. & 32 others, Johnson, N., McWilliam Leitch, E. C., Li, K., MacLean, A., Mair, D., McAllister, D. A., McCrone, J. T., McDonald, S. E., McHugh, M. P., Morris, A. K., Nichols, J., Niebel, M., Nomikou, K., Orton, R. J., O’Toole, Á., Palmarini, M., Parcell, B. J., Parr, Y. A., Rambaut, A., Rooke, S., Shaaban, S., Shah, R., Singer, J. B., Smollett, K., Starinskij, I., Tong, L., Sreenu, V. B., Wastnedge, E., Holden, M. T. G., Robertson, D. L., Templeton, K. & Thomson, E. C., Jan 2021, In: Nature Microbiology. 6, 1, p. 112-122 11 p.

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    21 Citations (Scopus)
  • Genomic insights into the biosynthesis and physiology of the cyanobacterial neurotoxin 2,4-diaminobutanoic acid (2,4-DAB)

    Mantas, M. J. Q., Nunn, P. B., Ke, Z., Codd, G. A. & Barker, D., Dec 2021, In: Phytochemistry. 192, 14 p., 112953.

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  • Genomic integration of oncogenic HPV and gain of the human telomerase gene TERC at 3q26 are strongly associated events in the progression of uterine cervical dysplasia to invasive cancer

    Hopman, A. H. N., Theelen, W., Hommelberg, P. P. H., Kamps, M. A. F., Herrington, C. S., Morrison, L. E., Speel, E. -J. M., Smedts, F. & Ramaekers, F. C. S., 2006, In: Journal of Pathology. 210, 4, p. 412-419 8 p.

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    104 Citations (Scopus)
  • Genomic organisation of plant U14 snoRNA genes

    Leader, D. J., Sanders, J. F., Turnbull-Ross, A., Waugh, R. & Brown, J. W. S., 1 May 1995, In: Biochemical Society Transactions. 23, 2, p. 314s 1 p.

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    1 Citation (Scopus)
  • Genomic resources and tools for gene function analysis in potato

    Bryan, G. J. & Hein, I., 2008, In: International Journal of Plant Genomics. 2008, 9 p., 216513.

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    9 Citations (Scopus)
  • Genomics, molecular genetics & biotechnology: Quantitative trait loci for Fusarium head blight resistance in barley detected in a two-rowed by six-rowed population

    Mesfin, A., Smith, K. P., Dill-Macky, R., Evans, C. K., Waugh, R., Gustus, C. D. & Muehlbauer, G. J., 1 Jan 2003, In: Crop Science. 43, 1, p. 307-318 12 p.

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    83 Citations (Scopus)
  • Genomic-scale prioritization of drug targets: the TDR Targets database

    Agüero, F., Al-Lazikani, B., Aslett, M., Berriman, M., Buckner, F. S., Campbell, R. K., Carmona, S., Carruthers, I. M., Chan, A. W. E., Chen, F., Crowther, G. J., Doyle, M. A., Hertz-Fowler, C., Hopkins, A. L., McAllister, G., Nwaka, S., Overington, J. P., Pain, A., Paolini, G. V., Pieper, U. & 8 others, Ralph, S. A., Riechers, A., Roos, D. S., Sali, A., Shanmugam, D., Suzuki, T., Van Voorhis, W. C. & Verlinde, C. L. M. J., 2008, In: Nature Reviews Drug Discovery. 7, 11, p. 900-907 8 p.

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    229 Citations (Scopus)
  • Genomic Selection in multi-environment crop trials

    Oakey, H., Cullis, B., Thompson, R., Comradan, J., Halpin, C. & Waugh, R., 1 May 2016, In: G3: Genes | Genomes | Genetics. 6, 5, p. 1313-1326 14 p.

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  • Genomic survey of pathogenicity determinants and VNTR markers in the cassava bacterial pathogen Xanthomonas axonopodis pv. manihotis strain CIO151

    Arrieta-Ortiz, M. L., Rodríguez-R, L. M., Pérez-Quintero, A. L., Poulin, L., Díaz, A. C., Arias Rojas, N., Trujillo, C., Restrepo Benavides, M., Bart, R., Boch, J., Boureau, T., Darrasse, A., David, P., Dugé de Bernonville, T., Fontanilla, P., Gagnevin, L., Guérin, F., Jacques, M-A., Lauber, E., Lefeuvre, P. & 23 others, Medina, C., Medina, E., Montenegro, N., Muñoz Bodnar, A., Noël, L. D., Ortiz Quiñones, J. F., Osorio, D., Pardo, C., Patil, P. B., Poussier, S., Pruvost, O., Robène-Soustrade, I., Ryan, R. P., Tabima, J., Urrego Morales, O. G., Vernière, C., Carrere, S., Verdier, V., Szurek, B., Restrepo, S., López, C., Koebnik, R. & Bernal, A., Nov 2013, In: PLoS ONE. 8, 11, 18 p., e79704.

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    28 Citations (Scopus)
  • Genotoxic Damage Activates the AMPK-α1 Isoform in the Nucleus via Ca2+/CaMKK2 Signaling to Enhance Tumor Cell Survival

    Vara Ciruelos, D., Dandapani, M., Gray, A., Agbani, E. O., Evans, A. M. & Hardie, D. G., Feb 2018, In: Molecular Cancer Research. 16, 2, p. 345-357 13 p.

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  • Genotoxicity of fecal water in a free-living Irish population

    Woods, J. A., Dunne, C., Collins, J. K., Shanahan, F. & O'Brien, N. M., 2002, In: Nutrition and Cancer. 42, 1, p. 62-9 8 p.

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    10 Citations (Scopus)
  • Genotype at the P554L Variant of the Hexose-6 Phosphate Dehydrogenase Gene Is Associated with Carotid Intima-Medial Thickness

    Rahman, T. J., Walker, E. A., Mayosi, B. M., Hall, D. H., Avery, P. J., Connell, J. M. C., Watkins, H., Stewart, P. M. & Keavney, B., 12 Aug 2011, In: PLoS ONE. 6, 8, p. - 7 p., e23248.

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  • Genotype-Dependent Induction of Transmissible Chromosomal Instability by γ-Radiation and the Benzene Metabolite Hydroquinone

    Gowans, I. D., Lorimore, S. A., McIlrath, J. & Wright, E., 2005, In: Cancer Research. 65, 9, p. 3527-3530 4 p.

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    Fu, T., Leachman, S. A., Wilson, N. J., Smith, F. J. D., Schwartz, M. E. & Tang, J. Y., May 2011, In: Journal of Investigative Dermatology. 131, 5, p. 1025-1028 4 p.

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  • Genotypes of glutathione transferase M1 and P1 and their significance for lung DNA adduct levels and cancer risk

    Ryberg, D., Skaug, V., Hewer, A., Phillips, D. H., Harries, L. W., Wolf, C. R., Øgreid, D., Ulvik, A., Vu, P. & Haugen, A., 1 Jul 1997, In: Carcinogenesis. 18, 7, p. 1285-1289 5 p.

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  • Genotypic variation in the ability of landraces and commercial cereal varieties to avoid manganese deficiency in soils with limited manganese availability: is there a role for root-exuded phytases?

    George, T. S., French, A. S., Brown, L. K., Karley, A. J., White, P. J., Ramsay, L. & Daniell, T. J., Jul 2014, In: Physiologia Plantarum. 151, 3, p. 243-256 14 p.

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  • Gentamicin-induced readthrough and nonsense-mediated mRNA decay of SERPINB7 nonsense mutant transcripts

    Ohguchi, Y., Nomura, T., Suzuki, S., Takeda, M., Miyauchi, T., Mizuno, O., Shinkuma, S., Fujita, Y., Nemoto, O., Ono, K., McLean, W. H. I. & Shimizu, H., 1 Apr 2018, In: Journal of Investigative Dermatology. 138, 4, p. 836-843 8 p.

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  • Genuine partnership and equitable research: Working “with” older people for the development of a smart activity monitoring system

    Pratesi, A., Sixsmith, J. & Woolrych, R., 2013, In: Innovation Journal. 18, 3, p. 1-17 17 p., 6.

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  • Geobacillus stearothermophilus 6-phosphogluconate dehydrogenase complexed with 6-phosphogluconate

    Cameron, S., Martini, V. P., Iulek, J. & Hunter, W. N., May 2009, In: Acta Crystallographica F-Structural Biology and Crystallization Communications. 65, p. 450-454 5 p.

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