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• Xenopus Mcm10 is a CDK-substrate required for replication fork stability

  Chadha, G. S., Gambus, A., Gillespie, P. J. & Blow, J., 2016, In: Cell Cycle. 15, 16, p. 2183-2195 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Xenopus
  • S Phase
  • Chromatin
  • Replication Origin
  • Ovum
  14 Citations (Scopus)

  258 Downloads (Pure)

• Xenopus cell-free extracts and their contribution to the study of DNA replication and other complex biological processes

  Blow, J. J. & Laskey, R. A., 2016, In: International Journal of Developmental Biology. 60, 7-9, p. 201-207 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cell Extracts
  • Xenopus
  • Ovum
  • DNA Replication
  • Biological Phenomena
  4 Citations (Scopus)

  194 Downloads (Pure)

• Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1

  Poh, W. T., Chadha, G. S., Gillespie, P. J., Kaldis, P. & Blow, J. J., 8 Jan 2014, In: Open Biology. 4, January, 130138.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Protein Phosphatase 1
  • Chromosomes
  • Xenopus
  • S Phase
  • Maintenance
  21 Citations (Scopus)

  152 Downloads (Pure)

• Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells

  Moreno, A., Carrington, J. T., Albergante, L., Al Mamun, M., Haagensen, E. J., Komseli, E-S., Gorgoulis, V. G., Newman, T. J. & Blow, J., 27 Sep 2016, In: Proceedings of the National Academy of Sciences. 113, 39, p. E5757-E5764 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Replication Origin
  • Mitosis
  • S Phase
  • DNA
  • Yeasts
  56 Citations (Scopus)

  435 Downloads (Pure)

• Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability

  Lachaud, C., Moreno, A., Marchesi, F., Toth, R., Blow, J. J. & Rouse, J., 19 Feb 2016, In: Science. 351, 6275, p. 846-849 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genomic Instability
  • DNA Replication
  • Personnel Selection
  • Ubiquitination
  • Chromosome Aberrations
  65 Citations (Scopus)

• The SMC-5/6 Complex and the HIM-6 (BLM) Helicase Synergistically Promote Meiotic Recombination Intermediate Processing and Chromosome Maturation during Caenorhabditis elegans Meiosis

  Hong, Y., Sonneville, R., Agostinho, A., Meier, B., Wang, B., Blow, J. J. & Gartner, A., 24 Mar 2016, In: PLoS Genetics. 12, 3, e1005872.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Chromosomes, Human, Pair 5
  • Meiosis
  • Caenorhabditis elegans
  • recombination
  • chromosome
  13 Citations (Scopus)

  307 Downloads (Pure)

• The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability

  Ho, T. L. F., Guilbaud, G., Blow, J. J., Sale, J. E. & Watson, C. J., 26 Apr 2016, In: Cell Reports. 15, 4, p. 724-734 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Epithelial Cells
  • Zinc Fingers
  • Genomic Instability
  • Cells
  • Zinc
  4 Citations (Scopus)

  158 Downloads (Pure)

• The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines

  Gardner, N. J., Gillespie, P. J., Carrington, J. T., Shanks, E. J., McElroy, S. P., Haagensen, E. J., Frearson, J. A., Woodland, A. & Blow, J. J., 17 Aug 2017, In: Cell Chemical Biology. 24, 8, p. 981-992.e4 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Origin Recognition Complex
  • Licensure
  • Amines
  • DNA
  • Cells
  5 Citations (Scopus)

  159 Downloads (Pure)

• The dynamics of replication licensing in live Caenorhabditis elegans embryos

  Sonneville, R., Querenet, M., Craig, A., Gartner, A. & Blow, J. J., 23 Jan 2012, In: Journal of Cell Biology. 196, 2, p. 233-246 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  50 Citations (Scopus)

  195 Downloads (Pure)

• The contribution of dormant origins to genome stability: from cell biology to human genetics

  Alver, R. C., Chadha, G. S. & Blow, J. J., Jul 2014, In: DNA Repair. 19, p. 182-189 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cytology
  • Genetics
  • Human Genetics
  • Genomic Instability
  • Licensure
  53 Citations (Scopus)

  243 Downloads (Pure)

• Reversal of DDK-mediated MCM phosphorylation by Rif1-PP1 regulates replication initiation and replisome stability independently of ATR/Chk1

  Alver, R. C., Chadha, G. S., Gillespie, P. J. & Blow, J. J., 7 Mar 2017, In: Cell Reports. 18, 10, p. 2508-2520 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Phosphorylation
  • Protein Phosphatase 1
  • Multicarrier modulation
  • Phosphotransferases
  • PHA 767491
  43 Citations (Scopus)

  180 Downloads (Pure)

• Re-replication induced by geminin depletion occurs from G2 and is enhanced by checkpoint activation

  Klotz-Noack, K., McIntosh, D., Schurch, N., Pratt, N. & Blow, J. J., 15 May 2012, In: Journal of Cell Science. 125, 10, p. 2436-2445 10 p.

  Research output: Contribution to journal › Article › peer-review
  40 Citations (Scopus)

• Preparation and use of Xenopus egg extracts to study DNA replication and chromatin associated proteins

  Gillespie, P. J., Gambus, A. & Blow, J. J., Jun 2012, In: Methods. 57, 2, p. 203-13 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Xenopus
  • Ovum
  • DNA Replication
  • Chromatin
  • Cell Cycle
  38 Citations (Scopus)

• Optimal Placement of Origins for DNA Replication

  Karschau, J., Blow, J. J. & de Moura, A. P. S., 30 Jan 2012, In: Physical Review Letters. 108, 5, p. - 5 p., 058101.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• Inevitability and containment of replication errors for eukaryotic genome lengths spanning Megabase to Gigabase

  Al Mamun, M., Albergante, L., Moreno, A., Carrington, J. T., Blow, J. & Newman, T. J., 27 Sep 2016, In: Proceedings of the National Academy of Sciences. 113, 39, p. E5765-E5774 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Replication Origin
  • Genome
  • Genome Size
  • Datasets
  • Yeasts
  17 Citations (Scopus)

  530 Downloads (Pure)

• Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans

  Pelisch, F., Sonneville, R., Pourkarimi, E., Agostinho, A., Blow, J. J., Gartner, A. & Hay, R. T., 5 Dec 2014, In: Nature Communications. 5, 12 p., 5485.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • chromosomes
  • Chromosomes
  • progressions
  • Caenorhabditis elegans
  • Ubiquitin
  32 Citations (Scopus)

• Dynamic interactions of high Cdt1 and geminin levels regulate S phase in early Xenopus embryos

  Kisielewska, J. & Blow, J. J., 1 Jan 2012, In: Development. 139, 1, p. 63-74 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  18 Citations (Scopus)

• Dormant Origins, the Licensing Checkpoint, and the Response to Replicative Stresses

  McIntosh, D. & Blow, J. J., Oct 2012, In: Cold spring harbor perspectives in biology. 4, 10, 10 p., 012955.

  Research output: Contribution to journal › Article › peer-review

  • Licensure
  • Meier-Gorlin syndrome
  • Cell proliferation
  • Maintenance
  • Replication Origin
  75 Citations (Scopus)

• Direct non transcriptional role of NF-Y in DNA replication

  Benatti, P., Belluti, S., Miotto, B., Neusiedler, J., Dolfini, D., Drac, M., Basile, V., Schwob, E., Mantovani, R., Blow, J. J. & Imbriano, C., 1 Apr 2016, In: Biochimica et Biophysica Acta. Molecular Cell Research. 1863, 4, p. 673-685 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • DNA Replication
  • S Phase
  • DNA
  • Cell-Free System
  • Xenopus
  8 Citations (Scopus)

  170 Downloads (Pure)

• Defects in the origin licensing checkpoint stresses cells exiting G0

  Blow, J. J., 1 Jul 2019, In: Journal of Cell Biology. 218, 7, p. 2080-2081 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Licensure
  • Replication Origin
  2 Citations (Scopus)

  93 Downloads (Pure)

• Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

  Galanos, P., Vougas, K., Walter, D., Polyzos, A., Maya-Mendoza, A., Haagensen, E. J., Kokkalis, A., Roumelioti, F-M., Gagos, S., Tzetis, M., Canovas, B., Igea, A., Ahuja, A. K., Zellweger, R., Havaki, S., Kanavakis, E., Kletsas, D., Roninson, I. B., Garbis, S. D., Lopes, M. & 7 others, Nebreda, A., Thanos, D., Blow, J. J., Townsend, P., Sørensen, C. S., Bartek, J. & Gorgoulis, V. G., Jul 2016, In: Nature Cell Biology. 18, 7, p. 777-789 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Genomic Instability
  • Licensure
  • Cyclin-Dependent Kinase Inhibitor p21
  • Neoplasms
  • Replication Origin
  114 Citations (Scopus)

  700 Downloads (Pure)

• Cell cycle synchronization in xenopus egg extracts

  Gillespie, P. J., Neusiedler, J., Creavin, K., Chadha, G. S. & Blow, J., 2016, Cell cycle oscillators: methods and protocols. Coutts, A. S. & Weston, L. (eds.). New York: Humana Press, p. 101-147 47 p. (Methods in Molecular Biology; vol. 1342).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

  • Xenopus
  • Ovum
  • Cell Cycle
  • Eukaryotic Cells
  • Cell-Free System
  5 Citations (Scopus)

• Buffered Qualitative Stability explains the robustness and evolvability of transcriptional networks

  Albergante, L., Blow, J. J. & Newman, T. J., 2 Sep 2014, In: eLife. 3, 28 p., e02863.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Gene Regulatory Networks
  • Physiological Adaptation
  • Neoplasms
  • Cells
  • Genes
  17 Citations (Scopus)

  190 Downloads (Pure)