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  • Blair Smith
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  • Article

    A catalog of genetic loci associated with kidney function from analyses of a million individuals

    LifeLines Cohort Study, Wuttke, M., Li, Y., Li, M., Sieber, K. B., Feitosa, M. F., Gorski, M., Tin, A., Wang, L., Chu, A. Y., Hoppmann, A., Kirsten, H., Giri, A., Chai, J-F., Sveinbjornsson, G., Tayo, B. O., Nutile, T., Fuchsberger, C., Marten, J., Cocca, M. & 33 others, Ghasemi, S., Xu, Y., Horn, K., Noce, D., van der Most, P. J., Sedaghat, S., Yu, Z., Akiyama, M., Afaq, S., Ahluwalia, T. S., Almgren, P., Amin, N., Ärnlöv, J., Bakker, S. J. L., Bansal, N., Baptista, D., Bergmann, S., Biggs, M. L., Biino, G., Boehnke, M., Boerwinkle, E., Boissel, M., Bottinger, E. P., Boutin, T. S., Brenner, H., Brumat, M., Burkhardt, R., Butterworth, A. S., Campana, E., Campbell, A., Smith, B. H., Köttgen, A. & Pattaro, C., Jun 2019, In : Nature Genetics. 51, 6, p. 957-972 16 p.

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    58 Citations (Scopus)
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  • A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway is Associated with Major Depressive Disorder

    Zeng, Y., Navarro, P., Fernandez-Pujals, A. M., Hall, L. S., Clarke, T-K., Thomson, P. A., Smith, B. H., Hocking, L. J., Padmanabhan, S., Hayward, C., MacIntyre, D. J., Wray, N. R., Deary, I. J., Porteous, D. J., Haley, C. S., McIntosh, A. M. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 15 Feb 2017, In : Biological Psychiatry. 81, 4, p. 336-346 11 p.

    Research output: Contribution to journalArticlepeer-review

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    17 Citations (Scopus)
    400 Downloads (Pure)
  • Alzheimer's disease risk factor complement receptor 1 is associated with depression

    Hamilton, G., Evans, K. L., MacIntyre, D. J., Deary, I. J., Dominiczak, A., Smith, B. H., Morris, A. D., Porteous, D. J. & Thomson, P. A., 2012, In : Neuroscience Letters. 510, 1, p. 6-9 4 p.

    Research output: Contribution to journalArticlepeer-review

    11 Citations (Scopus)
  • A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

    LifeLines Cohort Study, Sung, Y. J., de Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D. & 40 others, Marten, J., Musani, S. K., Kilpeläinen, T. O., Richard, M. A., Aslibekyan, S., Bartz, T. M., Dorajoo, R., Li, C., Liu, Y., Rankinen, T., Smith, A. V., Tajuddin, S. M., Tayo, B. O., Zhao, W., Zhou, Y., Matoba, N., Sofer, T., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Giulianini, F., Goel, A., Harris, S. E., Hartwig, F. P., Connell, J. M., Smith, B. H., Rotter, J. I., Franks, P. W., Rice, K., Elliott, P., Caulfield, M. J., Gauderman, W. J., Munroe, P. B., Rao, D. C. & Morrison, A. C., 1 Aug 2019, In : Human Molecular Genetics. 28, 15, p. 2615-2633 19 p.

    Research output: Contribution to journalArticlepeer-review

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    4 Citations (Scopus)
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  • Assessing the presence of shared genetic architecture between Alzheimer's disease and major depressive disorder using genome-wide association data

    Gibson, J., Russ, T. C., Adams, M. J., Clarke, T-K., Howard, D. M., Hall, L. S., Fernandez-Pujals, A. M., Wigmore, E. M., Hayward, C., Davies, G., Murray, A. D., Smith, B. H., Porteous, D. J., Deary, I. J. & McIntosh, A. M., 18 Apr 2017, In : Translational Psychiatry. 7, p. 1-8 8 p., e1094.

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    13 Citations (Scopus)
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  • Associations of autozygosity with a broad range of human phenotypes

    Clark, D. W., Okada, Y., Moore, K. H. S., Mason, D., Pirastu, N., Gandin, I., Mattsson, H., Barnes, C. L. K., Lin, K., Zhao, J. H., Deelen, P., Rohde, R., Schurmann, C., Guo, X., Giulianini, F., Zhang, W., Medina-Gomez, C., Karlsson, R., Bao, Y., Bartz, T. M. & 416 others, Baumbach, C., Biino, G., Bixley, M. J., Brumat, M., Chai, J-F., Corre, T., Cousminer, D. L., Dekker, A. M., Eccles, D. A., van Eijk, K. R., Fuchsberger, C., Gao, H., Germain, M., Gordon, S. D., de Haan, H. G., Harris, S. E., Hofer, E., Huerta-Chagoya, A., Igartua, C., Jansen, I. E., Jia, Y., Kacprowski, T., Karlsson, T., Kleber, M. E., Li, S. A., Li-Gao, R., Mahajan, A., Matsuda, K., Meidtner, K., Meng, W., Montasser, M. E., van der Most, P. J., Munz, M., Nutile, T., Palviainen, T., Prasad, G., Prasad, R. B., Priyanka, T. D. S., Rizzi, F., Salvi, E., Sapkota, B. R., Shriner, D., Skotte, L., Smart, M. C., Smith, A. V., van der Spek, A., Spracklen, C. N., Strawbridge, R. J., Tajuddin, S. M., Trompet, S., Turman, C., Verweij, N., Viberti, C., Wang, L., Warren, H. R., Wootton, R. E., Yanek, L. R., Yao, J., Yousri, N. A., Zhao, W., Adeyemo, A. A., Afaq, S., Aguilar-Salinas, C. A., Akiyama, M., Albert, M. L., Allison, M. A., Alver, M., Aung, T., Azizi, F., Bentley, A. R., Boeing, H., Boerwinkle, E., Borja, J. B., de Borst, G. J., Bottinger, E. P., Broer, L., Campbell, H., Chanock, S., Chee, M-L., Chen, G., Chen, Y-D. I., Chen, Z., Chiu, Y-F., Cocca, M., Collins, F. S., Concas, M. P., Corley, J., Cugliari, G., van Dam, R. M., Damulina, A., Daneshpour, M. S., Day, F. R., Delgado, G. E., Dhana, K., Doney, A. S. F., Dörr, M., Doumatey, A. P., Dzimiri, N., Ebenesersdóttir, S. S., Elliott, J., Elliott, P., Ewert, R., Felix, J. F., Fischer, K., Freedman, B. I., Girotto, G., Goel, A., Gögele, M., Goodarzi, M. O., Graff, M., Granot-Hershkovitz, E., Grodstein, F., Guarrera, S., Gudbjartsson, D. F., Guity, K., Gunnarsson, B., Guo, Y., Hagenaars, S. P., Haiman, C. A., Halevy, A., Harris, T. B., Hedayati, M., van Heel, D. A., Hirata, M., Höfer, I., Hsiung, C. A., Huang, J., Hung, Y-J., Ikram, M. A., Jagadeesan, A., Jousilahti, P., Kamatani, Y., Kanai, M., Kerrison, N. D., Kessler, T., Khaw, K-T., Khor, C. C., de Kleijn, D. P. V., Koh, W-P., Kolcic, I., Kraft, P., Krämer, B. K., Kutalik, Z., Kuusisto, J., Langenberg, C., Launer, L. J., Lawlor, D. A., Lee, I-T., Lee, W-J., Lerch, M. M., Li, L., Liu, J., Loh, M., London, S. J., Loomis, S., Lu, Y., Luan, J., Mägi, R., Manichaikul, A. W., Manunta, P., Másson, G., Matoba, N., Mei, X. W., Meisinger, C., Meitinger, T., Mezzavilla, M., Milani, L., Millwood, I. Y., Momozawa, Y., Moore, A., Morange, P-E., Moreno-Macías, H., Mori, T. A., Morrison, A. C., Muka, T., Murakami, Y., Murray, A. D., de Mutsert, R., Mychaleckyj, J. C., Nalls, M. A., Nauck, M., Neville, M. J., Nolte, I. M., Ong, K. K., Orozco, L., Padmanabhan, S., Pálsson, G., Pankow, J. S., Pattaro, C., Pattie, A., Polasek, O., Poulter, N., Pramstaller, P. P., Quintana-Murci, L., Räikkönen, K., Ralhan, S., Rao, D. C., van Rheenen, W., Rich, S. S., Ridker, P. M., Rietveld, C. A., Robino, A., van Rooij, F. J. A., Ruggiero, D., Saba, Y., Sabanayagam, C., Sabater-Lleal, M., Sala, C. F., Salomaa, V., Sandow, K., Schmidt, H., Scott, L. J., Scott, W. R., Sedaghati-Khayat, B., Sennblad, B., van Setten, J., Sever, P. J., Sheu, W. H-H., Shi, Y., Shrestha, S., Shukla, S. R., Sigurdsson, J. K., Sikka, T. T., Singh, J. R., Smith, B. H., Stančáková, A., Stanton, A., Starr, J. M., Stefansdottir, L., Straker, L., Sulem, P., Sveinbjornsson, G., Swertz, M. A., Taylor, A. M., Taylor, K. D., Terzikhan, N., Tham, Y-C., Thorleifsson, G., Thorsteinsdottir, U., Tillander, A., Tracy, R. P., Tusié-Luna, T., Tzoulaki, I., Vaccargiu, S., Vangipurapu, J., Veldink, J. H., Vitart, V., Völker, U., Vuoksimaa, E., Wakil, S. M., Waldenberger, M., Wander, G. S., Wang, Y. X., Wareham, N. J., Wild, S., Yajnik, C. S., Yuan, J-M., Zeng, L., Zhang, L., Zhou, J., Amin, N., Asselbergs, F. W., Bakker, S. J. L., Becker, D. M., Lehne, B., Bennett, D. A., van den Berg, L. H., Berndt, S. I., Bharadwaj, D., Bielak, L. F., Bochud, M., Boehnke, M., Bouchard, C., Bradfield, J. P., Brody, J. A., Campbell, A., Carmi, S., Caulfield, M. J., Cesarini, D., Chambers, J. C., Chandak, G. R., Cheng, C-Y., Ciullo, M., Cornelis, M., Cusi, D., Smith, G. D., Deary, I. J., Dorajoo, R., van Duijn, C. M., Ellinghaus, D., Erdmann, J., Eriksson, J. G., Evangelou, E., Evans, M. K., Faul, J. D., Feenstra, B., Feitosa, M., Foisy, S., Franke, A., Friedlander, Y., Gasparini, P., Gieger, C., Gonzalez, C., Goyette, P., Grant, S. F. A., Griffiths, L. R., Groop, L., Gudnason, V., Gyllensten, U., Hakonarson, H., Hamsten, A., van der Harst, P., Heng, C-K., Hicks, A. A., Hochner, H., Huikuri, H., Hunt, S. C., Jaddoe, V. W. V., De Jager, P. L., Johannesson, M., Johansson, Å., Jonas, J. B., Jukema, J. W., Junttila, J., Kaprio, J., Kardia, S. L. R., Karpe, F., Kumari, M., Laakso, M., van der Laan, S. W., Lahti, J., Laudes, M., Lea, R. A., Lieb, W., Lumley, T., Martin, N. G., März, W., Matullo, G., McCarthy, M. I., Medland, S. E., Merriman, T. R., Metspalu, A., Meyer, B. F., Mohlke, K. L., Montgomery, G. W., Mook-Kanamori, D., Munroe, P. B., North, K. E., Nyholt, D. R., O'connell, J. R., Ober, C., Oldehinkel, A. J., Palmas, W., Palmer, C., Pasterkamp, G. G., Patin, E., Pennell, C. E., Perusse, L., Peyser, P. A., Pirastu, M., Polderman, T. J. C., Porteous, D. J., Posthuma, D., Psaty, B. M., Rioux, J. D., Rivadeneira, F., Rotimi, C., Rotter, J. I., Rudan, I., Den Ruijter, H. M., Sanghera, D. K., Sattar, N., Schmidt, R., Schulze, M. B., Schunkert, H., Scott, R. A., Shuldiner, A. R., Sim, X., Small, N., Smith, J. A., Sotoodehnia, N., Tai, E-S., Teumer, A., Timpson, N. J., Toniolo, D., Tregouet, D-A., Tuomi, T., Vollenweider, P., Wang, C. A., Weir, D. R., Whitfield, J. B., Wijmenga, C., Wong, T-Y., Wright, J., Yang, J., Yu, L., Zemel, B. S., Zonderman, A. B., Perola, M., Magnusson, P. K. E., Uitterlinden, A. G., Kooner, J. S., Chasman, D. I., Loos, R. J. F., Franceschini, N., Franke, L., Haley, C. S., Hayward, C., Walters, R. G., Perry, J. R. B., Esko, T., Helgason, A., Stefansson, K., Joshi, P. K., Kubo, M. & Wilson, J. F., 31 Oct 2019, In : Nature Communications. 10, 1, p. 1-17 17 p., 4957.

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  • A study of National Health Service management of chronic osteoarthritis and low back pain

    Hart, O. R., Uden, R. M., McMullan, J. E., Ritchie, M. S., Williams, T. D. & Smith, B. H., 2014, In : Primary Health Care Research and Development. 16, 2, p. 157-166 10 p.

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    4 Citations (Scopus)
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  • Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

    Understanding Society Scientific Group, Shrine, N., Guyatt, A. L., Erzurumluoglu, A. M., Jackson, V. E., Hobbs, B. D., Melbourne, C. A., Batini, C., Fawcett, K. A., Song, K., Sakornsakolpat, P., Li, X., Boxall, R., Reeve, N. F., Obeidat, M., Zhao, J. H., Wielscher, M., Weiss, S., Kentistou, K. A., Cook, J. P. & 33 others, Sun, B. B., Zhou, J., Hui, J., Karrasch, S., Imboden, M., Harris, S. E., Marten, J., Enroth, S., Kerr, S. M., Surakka, I., Vitart, V., Lehtimäki, T., Allen, R. J., Bakke, P. S., Beaty, T. H., Bleecker, E. R., Bossé, Y., Brandsma, C-A., Chen, Z., Crapo, J. D., Danesh, J., DeMeo, D. L., Dudbridge, F., Ewert, R., Gieger, C., Gulsvik, A., Hansell, A. L., Hao, K., Hoffman, J. D., Hokanson, J. E., Smith, B. H., Tobin, M. D. & Wain, L. V., Jun 2019, In : Nature Genetics. 51, 6, p. 1067 1 p.

    Research output: Contribution to journalArticlepeer-review

  • Chronic pain: a review of its epidemiology and associated factors in population-based studies

    Mills, S. E. E., Nicolson, K. P. & Smith, B. H., 1 Aug 2019, In : British Journal of Anaesthesia. 123, 2, p. e273-e283 11 p.

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    41 Citations (Scopus)
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  • Chronic pain, depression and cardiovascular disease linked through a shared genetic predisposition: Analysis of a family-based cohort and twin study

    van Hecke, O., Hocking, L. J., Torrance, N., Campbell, A., Padmanabhan, S., Porteous, D. J., McIntosh, A. M., Burri, A. V., Tanaka, H., Williams, F. M. K. & Smith, B. H., 22 Feb 2017, In : PLoS ONE. 12, 2, 19 p., e0170653.

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    19 Citations (Scopus)
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  • Cohort profile: The Scottish Research Register SHARE: A register of people interested in research participation linked to NHS datasets

    McKinstry, B., Sullivan, F. M., Vasishta, S., Armstrong, R., Hanley, J., Haughney, J., Philip, S., Smith, B. H., Wood, A. & Palmer, C. N. A., 1 Feb 2017, In : BMJ Open. 7, 2, p. 1-8 8 p., e013351.

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    12 Citations (Scopus)
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  • Commentary: a thesis that still warrants defence and promotion

    Smith, B. H., Guthrie, B., Sullivan, F. M. & Morris, A. D., 2012, In : International Journal of Epidemiology. 41, 6, p. 1518-1522 5 p.

    Research output: Contribution to journalArticlepeer-review

    6 Citations (Scopus)
  • Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

    Rietveld, C. A., Esko, T., Davies, G., Pers, T. H., Turley, P., Benyamin, B., Chabris, C. F., Emilsson, V., Johnson, A. D., Lee, J. J., Leeuw, C. D., Marioni, R. E., Medland, S. E., Miller, M. B., Rostapshova, O., van der Lee, S. J., Vinkhuyzen, A. A. E., Amin, N., Conley, D., Derringer, J. & 39 others, van Duijn, C. M., Fehrmann, R., Franke, L., Glaeser, E. L., Hansell, N. K., Hayward, C., Iacono, W. G., Ibrahim-Verbaas, C., Jaddoe, V., Karjalainen, J., Laibson, D., Lichtenstein, P., Liewald, D. C., Magnusson, P. K. E., Martin, N. G., McGue, M., McMahon, G., Pedersen, N. L., Pinker, S., Porteous, D. J., Posthuma, D., Rivadeneira, F., Smith, B. H., Starr, J. M., Tiemeier, H., Timpson, N. J., Trzaskowski, M., Uitterlinden, A. G., Verhulst, F. C., Ward, M. E., Wright, M. J., Davey Smith, G., Deary, I. J., Johannesson, M., Plomin, R., Visscher, P. M., Benjamin, D. J., Cesarini, D. & Koellinger, P. D., 23 Sep 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 38, p. 13790-13794 5 p.

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    132 Citations (Scopus)
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  • Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

    Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D. & 31 others, Hayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P. M., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, J. M., Kleber, M. E., Hollensted, M., Lohman, K., Rivera, N. V., Whitfield, J. B., Zhao, J. H., Stringham, H. M., Lyytikäinen, L-P., Huppertz, C., Willemsen, G., Smith, B. H. & CHARGE Consortium, Aug 2017, In : PLoS Genetics. 13, 8, p. e1006972 1 p.

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    2 Citations (Scopus)
  • Corrigendum to "Neuropathic pain in the general population:a systematic review of epidemiological studies": [PAIN® 155(4) pp. 654-662 (2014)] (DOI:10.1016/j.pain.2013.11.013)

    van Hecke, O., Austin, S. K., Khan, R. A., Smith, B. H. & Torrance, N., Sep 2014, In : Pain. 155, 9, p. 1907 1 p.

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    3 Citations (Scopus)
  • Does a history of depression actually mediate smoking-related pain? findings from a cross-sectional general population-based study

    van Hecke, O., Torrance, N., Cochrane, L., Cavanagh, J., Donnan, P. T., Padmanabhan, S., Porteous, D. J., Hocking, L. & Smith, B. H., Oct 2014, In : European Journal of Pain. 18, 9, p. 1223-1230 8 p.

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    5 Citations (Scopus)
  • Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n=19,762), UK Biobank (n=24,048) and the English Longitudinal Study of Ageing (n=5,766)

    Wigmore, E. M., Clarke, T-K., Howard, D. M., Adams, M. J., Hall, L. S., Zeng, Y., Gibson, J., Davies, G., Fernandez-Pujals, A. M., Thomson, P. A., Hayward, C., Smith, B. H., Hocking, L. J., Padmanabhan, S., Deary, I. J., Porteous, D., Nicodemus, K. K. & McIntosh, A. M., 15 Aug 2017, In : Translational Psychiatry. 7, 9 p., e1205.

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  • eHealth and the use of individually tailored information: a systematic review

    Conway, N., Webster, C., Smith, B. & Wake, D., Sep 2017, In : Health Informatics Journal. 23, 3, p. 201-233 16 p.

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    6 Citations (Scopus)
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  • Epidemiology of neuropathic pain and its impact on quality of life

    Smith, B. H. & Torrance, N., 1 Jun 2012, In : Current Pain and Headache Reports. 16, 3, p. 191-198 8 p.

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    130 Citations (Scopus)
  • Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

    Christophersen, I. E., Rienstra, M., Roselli, C., Yin, X., Geelhoed, B., Barnard, J., Lin, H., Arking, D. E., Smith, A. V., Albert, C. M., Chaffin, M., Tucker, N. R., Li, M., Klarin, D., Bihlmeyer, N. A., Low, S-K., Weeke, P. E., Müller-Nurasyid, M., Smith, J. G., Brody, J. A. & 31 others, Niemeijer, M. N., Dörr, M., Trompet, S., Huffman, J., Gustafsson, S., Schurmann, C., Kleber, M. E., Lyytikäinen, L-P., Seppälä, I., Malik, R., R V R Horimoto, A., Perez, M., Sinisalo, J., Aeschbacher, S., Thériault, S., Yao, J., Radmanesh, F., Weiss, S., Teumer, A., Choi, S. H., Weng, L-C., Clauss, S., Deo, R., Rader, D. J., Shah, S. H., Sun, A., Hopewell, J. C., Debette, S., Smith, B. H., Morris, A. P. & METASTROKE Consortium of the ISGC, Neurology Working Group of the CHARGE Consortium, 27 Jul 2017, In : Nature Genetics. 49, 8, p. 1286 1 p.

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    1 Citation (Scopus)
  • Estimating the burden of disease in chronic pain with and without neuropathic characteristics: does the choice between the EQ-5D and SF-6D matter?

    Torrance, N., Lawson, K. D., Afolabi, E., Bennett, M. I., Serpell, M. G., Dunn, K. M. & Smith, B. H., Oct 2014, In : Pain. 155, 10, p. 1996-2004 9 p.

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  • Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants

    Nagy, R., Boutin, T. S., Marten, J., Huffman, J. E., Kerr, S. M., Campbell, A., Evenden, L., Gibson, J., Amador, C., Howard, D. M., Navarro, P., Morris, A., Deary, I. J., Hocking, L. J., Padmanabhan, S., Smith, B. H., Joshi, P., Wilson, J. F., Hastie, N. D., Wright, A. F. & 5 others, McIntosh, A. M., Porteous, D. J., Haley, C. S., Vitart, V. & Hayward, C., 7 Mar 2017, In : Genome Medicine. 9, p. 1-14 14 p., 23.

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  • Factors affecting use of unscheduled care for people with advanced cancer: a retrospective cohort study in Scotland

    Mills, S., Buchanan, D., Guthrie, B., Donnan, P. & Smith, B., Dec 2019, In : British Journal of General Practice. 69, 689, p. e860-e868 9 p.

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  • Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

    Clarke, T-K., Adams, M. J., Howard, D. M., Xia, C., Davies, G., Hayward, C., Campbell, A., Padmanabhan, S., Smith, B., Murray, A., Porteous, D., Deary, I. J. & McIntosh, A. M., 25 Nov 2019, In : Molecular Psychiatry. 11 p.

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    1 Citation (Scopus)
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  • Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

    Understanding Society Scientific Group, Sakornsakolpat, P., Prokopenko, D., Lamontagne, M., Reeve, N. F., Guyatt, A. L., Jackson, V. E., Shrine, N., Qiao, D., Bartz, T. M., Kim, D. K., Lee, M. K., Latourelle, J. C., Li, X., Morrow, J. D., Obeidat, M., Wyss, A. B., Bakke, P., Barr, R. G., Beaty, T. H. & 35 others, Belinsky, S. A., Brusselle, G. G., Crapo, J. D., de Jong, K., DeMeo, D. L., Fingerlin, T. E., Gharib, S. A., Gulsvik, A., Hall, I. P., Hokanson, J. E., Kim, W. J., Lomas, D. A., London, S. J., Meyers, D. A., O’Connor, G. T., Rennard, S. I., Schwartz, D. A., Sliwinski, P., Sparrow, D., Strachan, D. P., Tal-Singer, R., Tesfaigzi, Y., Vestbo, J., Vonk, J. M., Yim, J. J., Zhou, X., Bossé, Y., Manichaikul, A., Lahousse, L., Silverman, E. K., Boezen, H. M., Wain, L. V., Tobin, M. D., Hobbs, B. D. & Cho, M. H., 1 Mar 2019, In : Nature Genetics. 51, 3, p. 494-505 12 p.

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    40 Citations (Scopus)
  • Genetic variation in hyperpolarization-activated cyclic nucleotide-gated channels and its relationship with neuroticism, cognition and risk of depression

    McIntosh, A. M., Simen, A. A., Evans, K. L., Hall, J., MacIntyre, D. J., Blackwood, D., Morris, A. D., Smith, B. H., Dominiczak, A., Porteous, D., Deary, I. J. & Thomson, P. A., 2012, In : Frontiers in Genetics. 3, 00116.

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    6 Citations (Scopus)
  • Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

    23andMe Research Team, Karlsson Linnér, R., Biroli, P., Kong, E., Meddens, S. F. W., Wedow, R., Fontana, M. A., Lebreton, M., Tino, S. P., Abdellaoui, A., Hammerschlag, A. R., Nivard, M. G., Okbay, A., Rietveld, C. A., Timshel, P. N., Trzaskowski, M., Vlaming, R. D., Zünd, C. L., Bao, Y., Buzdugan, L. & 22 others, Caplin, A. H., Chen, C. Y., Eibich, P., Fontanillas, P., Gonzalez, J. R., Joshi, P. K., Karhunen, V., Kleinman, A., Levin, R. Z., Lill, C. M., Meddens, G. A., Muntané, G., Sanchez-Roige, S., Rooij, F. J. V., Taskesen, E., Wu, Y., Zhang, F., Auton, A., Boardman, J. D., Clark, D. W., Conlin, A. & Beauchamp, J. P., 2019, In : Nature Genetics. 51, 2, p. 245-257 13 p.

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    58 Citations (Scopus)
  • Genome-wide association analysis identifies six new loci associated with forced vital capacity

    Loth, D. W., Artigas, M. S., Gharib, S. A., Wain, L. V., Franceschini, N., Koch, B., Pottinger, T. D., Smith, A. V., Duan, Q., Oldmeadow, C., Lee, M. K., Strachan, D. P., James, A. L., Huffman, J. E., Vitart, V., Ramasamy, A., Wareham, N. J., Kaprio, J., Wang, X-Q., Trochet, H. & 33 others, Kähönen, M., Flexeder, C., Albrecht, E., Lopez, L. M., de Jong, K., Thyagarajan, B., Alves, A. C., Enroth, S., Omenaas, E., Joshi, P. K., Fall, T., Viñuela, A., Launer, L. J., Loehr, L. R., Fornage, M., Li, G., Wilk, J. B., Tang, W., Manichaikul, A., Lahousse, L., Harris, T. B., North, K. E., Rudnicka, A. R., Hui, J., Gu, X., Lumley, T., Wright, A. F., Hastie, N. D., Campbell, S., Generation Scotland, Smith, B. H., Tobin, M. D. & London, S. J., Jul 2014, In : Nature Genetics. 46, 7, p. 669-677 9 p.

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    85 Citations (Scopus)
  • Genome-wide association for major depression through age at onset stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

    Power, R. A., Tansey, K. E., Buttenschøn, H. N., Cohen-Woods, S., Bigdeli, T., Hall, L. S., Kutalik, Z., Lee, S. H., Ripke, S., Steinberg, S., Teumer, A., Viktorin, A., Wray, N. R., Arolt, V., Baune, B. T., Boomsma, D. I., Børglum, A. D., Byrne, E. M., Castelao, E., Craddock, N. & 33 others, Craig, I. W., Dannlowski, U., Deary, I. J., Degenhardt, F., Forstner, A. J., Gordon, S. D., Grabe, H. J., Grove, J., Hamilton, S. P., Hayward, C., Heath, A. C., Hocking, L. J., Homuth, G., Hottenga, J. J., Kloiber, S., Krogh, J., Landén, M., Lang, M., Levinson, D. F., Lichtenstein, P., Lucae, S., MacIntyre, D. J., Madden, P., Magnusson, P. K. E., Martin, N. G., McIntosh, A. M., Middeldorp, C. M., Milaneschi, Y., Montgomery, G. W., Smith, B. H., CONVERGE Consortium, CARDIoGRAM Consortium & GERAD1 Consortium, 15 Feb 2017, In : Biological Psychiatry. 81, 4, p. 325-335 11 p.

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  • Genome­-wide association study of alcohol consumption and genetic overlap with other health-­related traits in UK Biobank (=112,117)

    Clarke, T. K., Adams, M. J., Davies, G., Howard, D. M., Hall, L. S., Padmanabhan, S., Smith, B. H., Hayward, C., Porteous, D. J., Deary, I. J. & McIntosh, A. M., Oct 2017, In : Molecular Psychiatry. 22, 10, p. 1376-1384 9 p.

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  • Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank

    Meng, W., Adams, M. J., Palmer, C. N. A., 23andMe Research Team, Shi, J., Auton, A., Ryan, K. A., Jordan, J. M., Mitchell, B. D., Jackson, R. D., Yau, M. S., McIntosh, A. M. & Smith, B. H., 28 Aug 2019, In : Communications Biology. 2, p. 1-8 8 p., 321.

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  • Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

    Howard, D. M., Hall, L. S., Hafferty, J. D., Yanni, Z., Adams, M. J., Clarke, T-K., Porteous, D. J., Nagy, R., Hayward, C., Smith, B., Murray, A. D., Ryan, N. M., Evans, K. L., Haley, C. S., Deary, I. J., Thomson, P. A. & McIntosh, A. M., 30 Nov 2017, In : Translational Psychiatry. 7, p. 1-9 9 p., 1263.

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  • Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

    Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., Shen, X., Gandin, I., McDaid, A. F., Hansen, T. F., Gordon, S. D., Giulianini, F., Boutin, T. S., Abdellaoui, A., Zhao, W., Medina-Gomez, C. & 93 others, Bartz, T. M., Trompet, S., Lange, L. A., Raffield, L., van der Spek, A., Galesloot, T. E., Proitsi, P., Yanek, L. R., Bielak, L. F., Payton, A., Murgia, F., Concas, M. P., Biino, G., Tajuddin, S. M., Seppälä, I., Amin, N., Boerwinkle, E., Børglum, A. D., Campbell, A., Demerath, E. W., Demuth, I., Faul, J. D., Ford, I., Gialluisi, A., Gögele, M., Graff, M., Hingorani, A. D., Hottenga, J. J., Hougaard, D. M., Hurme, M. A., Ikram, M. A., Jylhä, M., Kuh, D., Ligthart, L., Lill, C. M., Lindenberger, U., Lumley, T., Mägi, R., Marques-Vidal, P., Medland, S. E., Milani, L., Nagy, R., Ollier, W. E. R., Peyser, P. A., Pramstaller, P. P., Ridker, P. M., Rivadeneira, F., Ruggiero, D., Saba, Y., Schmidt, R., Schmidt, H., Slagboom, P. E., Smith, B. H., Smith, J. A., Sotoodehnia, N., Steinhagen-Thiessen, E., van Rooij, F. J. A., Verbeek, A. L., Vermeulen, S. H., Vollenweider, P., Wang, Y., Werge, T., Whitfield, J. B., Zonderman, A. B., Lehtimäki, T., Evans, M. K., Pirastu, M., Fuchsberger, C., Bertram, L., Pendleton, N., Kardia, S. L. R., Ciullo, M., Becker, D. M., Wong, A., Psaty, B. M., van Duijn, C. M., Wilson, J. G., Jukema, J. W., Kiemeney, L. A., Uitterlinden, A. G., Franceschini, N., North, K. E., Weir, D. R., Metspalu, A., Boomsma, D. I., Hayward, C., Chasman, D. I., Martin, N. G., Sattar, N., Campbell, H., Esko, T., Kutalik, Z. & Wilson, J. F., 13 Oct 2017, In : Nature Communications. 8, p. 1-13 13 p., 910.

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  • Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

    Justice, A. E., Winkler, T. W., Feitosa, M. F., Graff, M., Fisher, V. A., Young, K. L., Barata, L., Deng, X., Czajkowski, J., Hadley, D., Ngwa, J. S., Ahluwalia, T. S., Chu, A. Y., Heard-Costa, N. L., Lim, E., Perez, J., Eicher, J. D., Kutalik, Z., Xue, L., Mahajan, A. & 297 others, Renström, F., Wu, J. M. W., Qi, Q., Ahmad, S., Alfred, T., Amin, N., Bielak, L. F., Bonnefond, A., Bragg-Gresham, J. L., Cadby, G., Chittani, M., Coggeshall, S., Corre, T., Direk, N., Eriksson, J., Fischer, K., Gorski, M., Neergaard Harder, M., Horikoshi, M., Huang, T., Huffman, J. E., Jackson, A. U., Justesen, J. M., Kanoni, S., Kinnunen, L., Kleber, M. E., Komulainen, P., Kumari, M., Lim, U., Luan, J., Lyytikäinen, L-P., Mangino, M., Manichaikul, A., Marten, J., Middelberg, R. P. S., Müller-Nurasyid, M., Navarro, P., Pérusse, L., Pervjakova, N., Sarti, C., Smith, A. V., Smith, J. A., Stančáková, A., Strawbridge, R. J., Stringham, H. M., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., van der Laan, S. W., van der Most, P. J., van Vliet-Ostaptchouk, J. V., Vedantam, S. L., Verweij, N., Vink, J. M., Vitart, V., Wu, Y., Yengo, L., Zhang, W., Hua Zhao, J., Zimmermann, M. E., Zubair, N., Abecasis, G. R., Adair, L. S., Afaq, S., Afzal, U., Bakker, S. J. L., Bartz, T. M., Beilby, J. P., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E. P., Braga, D., Buckley, B. M., Buyske, S., Campbell, H., Chambers, J. C., Collins, F. S., Curran, J. E., de Borst, G. J., de Craen, A. J. M., de Geus, E. J. C., Dedoussis, G., Delgado, G. E., den Ruijter, H. M., Eiriksdottir, G., Eriksson, A. L., Esko, T., Faul, J. D., Ford, I., Forrester, T., Gertow, K., Gigante, B., Glorioso, N., Gong, J., Grallert, H., Grammer, T. B., Grarup, N., Haitjema, S., Hallmans, G., Hamsten, A., Hansen, T., Harris, T. B., Hartman, C. A., Hassinen, M., Hastie, N. D., Heath, A. C., Hernandez, D., Hindorff, L. A., Hocking, L. J., Hollensted, M., Holmen, O. L., Homuth, G., Jan Hottenga, J., Huang, J., Hung, J., Hutri-Kähönen, N., Ingelsson, E., James, A. L., Jansson, J-O., Jarvelin, M-R., Jhun, M. A., Jørgensen, M. E., Juonala, M., Kähönen, M., Karlsson, M., Koistinen, H. A., Kolcic, I., Kolovou, G., Kooperberg, C., Krämer, B. K., Kuusisto, J., Kvaløy, K., Lakka, T. A., Langenberg, C., Launer, L. J., Leander, K., Lee, N. R., Lind, L., Lindgren, C. M., Linneberg, A., Lobbens, S., Loh, M., Lorentzon, M., Luben, R. N., Lubke, G., Ludolph-donislawski, A., Lupoli, S., Madden, P. A. F., Männikkö, R., Marques-Vidal, P., Martin, N. G., McKenzie, C. A., McKnight, B., Mellström, D., Menni, C., Montgomery, G. W., Musk, A. ., Narisu, N., Nauck, M., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Peyser, P. A., Pisinger, C., Porteous, D. J., Raitakari, O. T., Rankinen, T., Rao, D. C., Rasmussen-Torvik, L. J., Rawal, R., Rice, T. K., Ridker, P. M., Rose, L. M., Bien, S. A., Rudan, I., Sanna, S., Sarzynski, M. A., Sattar, N., Savonen, K., Schlessinger, D., Scholtens, S., Schurmann, C., Scott, R. A., Sennblad, B., Siemelink, M. A., Silbernagel, G., Slagboom, P. E., Snieder, H., Staessen, J. A., Stott, D. J., Swertz, M. A., Swift, A. J., Taylor, K. D., Tayo, B. O., Thorand, B., Thuillier, D., Tuomilehto, J., Uitterlinden, A. G., Vandenput, L., Vohl, M-C., Völzke, H., Vonk, J. M., Waeber, G., Waldenberger, M., Westendorp, R. G. J., Wild, S. H., Willemsen, G., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zhao, W., Zillikens, M. C., Baldassarre, D., Balkau, B., Bandinelli, S., Böger, C. A., Boomsma, D. I., Bouchard, C., Bruinenberg, M., Chasman, D. I., Chen, Y., Chines, P. S., Cooper, R. S., Cucca, F., Cusi, D., de Faire, U., Ferrucci, L., Franks, P. W., Froguel, P., Gordon-Larsen, P., Grabe, H-J., Gudnason, V., Haiman, C. A., Hayward, C., Hveem, K., Johnson, A. D., Wouter Jukema, J., Kardia, S. L. R., Kivimaki, M., Kooner, J. S., Kuh, D., Laakso, M., Lehtimäki, T., Marchand, L. L., März, W., McCarthy, M. I., Metspalu, A., Morris, A. P., Ohlsson, C., Palmer, L. J., Pasterkamp, G., Pedersen, O., Peters, A., Peters, U., Polasek, O., Psaty, B. M., Qi, L., Rauramaa, R., Smith, B. H., Sørensen, T. I. A., Strauch, K., Tiemeier, H., Tremoli, E., van der Harst, P., Vestergaard, H., Vollenweider, P., Wareham, N. J., Weir, D. R., Whitfield, J. B., Wilson, J. F., Tyrrell, J., Frayling, T. M., Barroso, I., Boehnke, M., Deloukas, P., Fox, C. S., Hirschhorn, J. N., Hunter, D. J., Spector, T. D., Strachan, D. P., van Duijn, C. M., Heid, I. M., Mohlke, K. L., Marchini, J. L., Loos, R. J. F., Kilpeläinen, T. O., Liu, C-T., Borecki, I. B., North, K. E. & Cupples, L. A., 26 Apr 2017, In : Nature Communications. 8, 19 p., 14977.

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  • Genome-wide physical activity interactions in adiposity: A meta-analysis of 200,452 adults

    Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., Den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D. & 31 others, Hayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, J. M., Kleber, M. E., Hollensted, M., Lohman, K., Rivera, N. V., Whitfield, J. B., Zhao, J. H., Stringham, H. M., Lyytikäinen, L-P., Huppertz, C., Willemsen, G., Smith, B. H. & CHARGE Consortium, EPIC-InterAct Consortium, PAGE Consortium , 27 Apr 2017, In : PLoS Genetics. 13, 4, 26 p., e1006528.

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  • Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated with Major Depressive Disorder

    Yanni, Z., Navarro, P., Shirali, M., Howard, D. M., Adams, M. J., Hall, L. S., Clarke, T-K., Thomson, P. A., Smith, B. H., Murray, A., Padmanabhan, S., Hayward, C., Boutin, T., MacIntyre, D. J., Lewis, C. M., Wray, N. R., Mehta, D., Penninx, B. W. J. H., Milaneschi, Y., Baune, B. T. & 20 others, Air, T., Hottenga, J-J., Mbarek, H., Castelao, E., Pistis, G., Schulze, T. G., Streit, F., Forstner, A. J., Byrne, E. M., Martin, N. G., Breen, G., Müller-Myhsok, B., Lucae, S., Kloiber, S., Domenici, E., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Deary, I. J., Porteous, D. J., Haley, C. S. & McIntosh, A. M., 1 Sep 2017, In : Biological Psychiatry. 82, 5, p. 312-321 10 p.

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  • Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK Biobank

    Howard, D. M., Adams, M. J., Clarke, T-K., Wigmore, E. M., Zeng, Y., Hagenaars, S. P., Lyall, D. M., Thomson, P. A., Evans, K. L., Porteous, D. J., Nagy, R., Hayward, C., Haley, C. S., Smith, B. H., Murray, A. D., Batty, G. D., Deary, I. J. & McIntosh, A. M., 10 Aug 2017, In : Wellcome Open Research. 2, p. 1-13 13 p., 61.

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  • Heritability of chronic pain in 2195 extended families

    Hocking, L. J., Morris, A. D., Dominiczak, A. F., Porteous, D. J., Smith, B. H. & Generation Scotland, Aug 2012, In : European Journal of Pain. 16, 7, p. 1053-1063 11 p.

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    45 Citations (Scopus)
  • "I feel so stupid because I can't give a proper answer..." How older adults describe chronic pain: a qualitative study

    Clarke, A., Anthony, G., Gray, D., Jones, D., McNamee, P., Schofield, P., Smith, B. H. & Martin, D., 2012, In : BMC Geriatrics. 12, 1, 78.

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    16 Citations (Scopus)
  • Implementation of Patient-Reported Outcomes (PROMs) from specialist pain clinics in England and Wales: experience from a nationwide study

    Price, C. M., C. de C. Williams, A., Smith, B. H. & Bottle, A., 1 Aug 2019, In : European Journal of Pain. 23, 7, p. 1368-1377 10 p.

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  • Insulin resistance: Genetic associations with depression and cognition in population based cohorts

    Frangou, S., Shirali, M., Adams, M. J., Howard, D. M., Gibson, J., Hall, L. S., Smith, B. H., Padmanabhan, S., Murray, A. D., Porteous, D. J., Haley, C. S., Deary, I. J., Clarke, T-K. & McIntosh, A. M., Jun 2019, In : Experimental Neurology. 316, p. 20-26 7 p.

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  • "I try and smile, I try and be cheery, I try not to be pushy. I try to say 'I'm here for help' but I leave feeling… worried": a qualitative study of perceptions of interactions with health professionals by community-based older adults with chronic pain

    Clarke, A., Martin, D., Jones, D., Schofield, P., Anthony, G., McNamee, P., Gray, D. & Smith, B. H., Sep 2014, In : PLoS ONE. 9, 9, 7 p., e105450.

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  • Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

    UK10K Consortium, 21 Jan 2019, In : Nature Communications. 10, 1, 357.

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  • Managing chronic pain in the non-specialist setting: a new SIGN guideline

    Smith, B. H., Hardman, J. D., Stein, A., Colvin, L. & SIGN Chronic Pain Guideline Development Group, 1 Jul 2014, In : British Journal of General Practice. 64, 624, p. e462-e464 3 p.

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    5 Citations (Scopus)
  • Molecular genetic contributions to socioeconomic status and intelligence

    Marioni, R. E., Davies, G., Hayward, C., Liewald, D., Kerr, S. M., Campbell, A., Luciano, M., Smith, B. H., Padmanabhan, S., Hocking, L. J., Hastie, N. D., Wright, A. F., Porteous, D. J., Visscher, P. M. & Deary, I. J., 2014, In : Intelligence. 44, May-June, p. 26-32 7 p.

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  • Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

    InterAct Consortium, LifeLines Cohort Study, de Vries, P. S., Brown, M. R., Bentley, A. R., Sung, Y. J., Winkler, T. W., Ntalla, I., Schwander, K., Kraja, A. T., Guo, X., Franceschini, N., Cheng, C-Y., Sim, X., Vojinovic, D., Huffman, J. E., Musani, S. K., Li, C., Feitosa, M. F., Richard, M. A. & 34 others, Noordam, R., Aschard, H., Bartz, T. M., Bielak, L. F., Deng, X., Dorajoo, R., Lohman, K. K., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Evangelou, E., Graff, M., Alver, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Goel, A., Hagemeijer, Y., Harris, S. E., Hartwig, F. P., He, M., Horimoto, A. R. V. R., Hsu, F-C., Jackson, A. U., Kasturiratne, A., Komulainen, P., Connell, J. M., Smith, B. H., Rao, D. C. & Morrison, A. C., 1 Jun 2019, In : American Journal of Epidemiology. 188, 6, p. 1033-1054 22 p.

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  • NeuPSIG: investing in solutions to the growing global challenge of neuropathic pain

    Smith, B. & Raja, S. N., 1 Oct 2017, In : British Journal of Anaesthesia. 119, 4, p. 705-708 4 p.

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  • Neuropathic pain in the general population: a systematic review of epidemiological studies

    van Hecke, O., Austin, S. K., Khan, R. A., Smith, B. H. & Torrance, N., Apr 2014, In : Pain. 155, 4, p. 654-662 9 p.

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    486 Citations (Scopus)