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Article

Adverse respiratory effect of acute beta-blocker exposure in asthma: a systematic review and meta-analysis of randomized controlled trials

Morales, D. R., Jackson, C., Lipworth, B. J., Donnan, P. T. & Guthrie, B., Apr 2014, In: Chest. 145, 4, p. 779-786

Research output: Contribution to journal › Article › peer-review

Allergic Rhinitis and its Impact on Asthma (ARIA): Achievements in 10 years and future needs

Bousquet, J., Schünemann, H. J., Samolinski, B., Demoly, P., Baena-Cagnani, C. E., Bachert, C., Bonini, S., Boulet, L. P., Bousquet, P. J., Brozek, J. L., Canonica, G. W., Casale, T. B., Cruz, A. A., Fokkens, W. J., Fonseca, J. A., Van Wijk, R. G., Grouse, L., Haahtela, T., Khaltaev, N., Kuna, P. & 213 others, Lockey, R. F., Lodrup Carlsen, K. C., Mullol, J., Naclerio, R., O'hehir, R. E., Ohta, K., Palkonen, S., Papadopoulos, N. G., Passalacqua, G., Pawankar, R., Price, D., Ryan, D., Simons, F. E. R., Togias, A., Williams, D., Yorgancioglu, A., Yusuf, O. M., Aberer, W., Adachi, M., Agache, I., Aït-Khaled, N., Akdis, C. A., Andrianarisoa, A., Annesi-Maesano, I., Ansotegui, I. J., Baiardini, I., Bateman, E. D., Bedbrook, A., Beghé, B., Beji, M., Bel, E. H., Ben Kheder, A., Bennoor, K. S., Bergmann, K. C., Berrissoul, F., Bieber, T., Bindslev Jensen, C., Blaiss, M. S., Boner, A. L., Bouchard, J., Braido, F., Brightling, C. E., Bush, A., Caballero, F., Calderon, M. A., Calvo, M. A., Camargos, P. A. M., Caraballo, L. R., Carlsen, K. H., Carr, W., Cepeda, A. M., Cesario, A., Chavannes, N. H., Chen, Y. Z., Chiriac, A. M., Chivato Pérez, T., Chkhartishvili, E., Ciprandi, G., Costa, D. J., Cox, L., Custovic, A., Dahl, R., Darsow, U., De Blay, F., Deleanu, D., Denburg, J. A., Devillier, P., Didi, T., Dokic, D., Dolen, W. K., Douagui, H., Dubakiene, R., Durham, S. R., Dykewicz, M. S., El-Gamal, Y., El-Meziane, A., Emuzyte, R., Fiocchi, A., Fletcher, M., Fukuda, T., Gamkrelidze, A., Gereda, J. E., González Diaz, S., Gotua, M., Guzmán, M. A., Hellings, P. W., Hellquist-Dahl, B., Horak, F., Hourihane, JOB., Howarth, P., Humbert, M., Ivancevich, J. C., Jackson, C., Just, J., Kalayci, O., Kaliner, M. A., Kalyoncu, A. F., Keil, T., Keith, P. K., Khayat, G., Kim, Y. Y., Koffi N'Goran, B., Koppelman, G. H., Kowalski, M. L., Kull, I., Kvedariene, V., Larenas-Linnemann, D., Le, L. T., Lemière, C., Li, J., Lieberman, P., Lipworth, B., Mahboub, B., Makela, M. J., Martin, F., Marshall, G. D., Martinez, F. D., Masjedi, M. R., Maurer, M., Mavale-Manuel, S., Mazon, A., Melen, E., Meltzer, E. O., Mendez, N. H., Merk, H., Mihaltan, F., Mohammad, Y., Morais-Almeida, M., Muraro, A., Nafti, S., Namazova-Baranova, L., Nekam, K., Neou, A., Niggemann, B., Nizankowska-Mogilnicka, E., Nyembue, T. D., Okamoto, Y., Okubo, K., Orru, M. P., Ouedraogo, S., Ozdemir, C., Panzner, P., Pali-Schöll, I., Park, H. S., Pigearias, B., Pohl, W., Popov, T. A., Postma, D. S., Potter, P., Rabe, K. F., Ratomaharo, J., Reitamo, S., Ring, J., Roberts, R., Rogala, B., Romano, A., Roman Rodriguez, M., Rosado-Pinto, J., Rosenwasser, L., Rottem, M., Sanchez-Borges, M., Scadding, G. K., Schmid-Grendelmeier, P., Sheikh, A., Sisul, J. C., Solé, D., Sooronbaev, T., Spicak, V., Spranger, O., Stein, R. T., Stoloff, S. W., Sunyer, J., Kogevinas, M., Szczeklik, A., Todo-Bom, A., Toskala, E., Tremblay, Y., Valenta, R., Valero, A. L., Valeyre, D., Valiulis, A., Valovirta, E., Van Cauwenberge, P., Vandenplas, O., Van Weel, C., Vichyanond, P., Viegi, G., Wang, D. Y., Wickman, M., Wöhrl, S., Wright, J., Yawn, B. P., Yiallouros, P. K., Zar, H. J., Zernotti, M. E., Zhong, N., Zidarn, M., Zuberbier, T., Oddie, S., Baigenzhin, A. K., Boakye, D. A., Briggs, A. H., Burney, P. G., Busse, W. W., Chuchalin, A. G., Haddad, H., Johnston, S. L., Levy, M. L., Mohammadi, A., Rezagui, D., Terreehorst, I., Warner, J. O. & Ang, C. S., 2012, In: Journal of Allergy and Clinical Immunology. 130, 5, p. 1049-1062 14 p.

Research output: Contribution to journal › Article › peer-review

374 Citations (Scopus)

Allopurinol in Patients with Pulmonary Hypertension Associated with Chronic Lung Disease

Liu Shiu Cheong, P. S. K., Lipworth, B. J., Weir-McCall, J. R., Houston, J. G. & Struthers, A. D., 25 Aug 2020, In: International Journal of Chronic Obstructive Pulmonary Disease. 2020, 15, p. 2015-2024 10 p.

Research output: Contribution to journal › Article › peer-review

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An algorithm recommendation for the pharmacological management of allergic rhinitis in the UK: a consensus statement from an expert panel

Lipworth, B., Newton, J., Ram, B., Small, I. & Schwarze, J., 23 Jan 2017, In: NPJ Primary Care Respiratory Medicine. 27, p. 1-8 8 p., 3.

Research output: Contribution to journal › Article › peer-review

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7 Citations (Scopus)

176 Downloads (Pure)

Anti-inflammatory reliever therapy for asthma

Lipworth, B., Chan, R. & RuiWen Kuo, C., Jan 2020, In: Annals of Allergy, Asthma & Immunology. 124, 1, p. 13-15 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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1 Citation (Scopus)

32 Downloads (Pure)

A randomized primary care trial of steroid titration against mannitol in persistent asthma: STAMINA trial

Lipworth, B. J., Short, P. M., Williamson, P. A., Clearie, K. L., Fardon, T. C. & Jackson, C. M., 2012, In: Chest. 141, 3, p. 607-15 9 p.

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Are we overlooking persistent small airways dysfunction in community-managed asthma?

Anderson, W. J., Zajda, E. & Lipworth, B. J., 2012, In: Annals of Allergy, Asthma & Immunology. 109, 3, p. 185-189 5 p.

Research output: Contribution to journal › Article › peer-review

48 Citations (Scopus)

Benefits of glycopyrrolate/formoterol fumarate metered dose inhaler (GFF MDI) in improving lung function and reducing exacerbations in patients with moderate-to-very severe COPD: a pooled analysis of the PINNACLE studies

Martinez, F. J., Lipworth, B. J., Rabe, K. F., Collier, D. J., Ferguson, G. T., Sethi, S., Feldman, G. J., O'Brien, G., Jenkins, M. & Reisner, C., 25 May 2020, In: Respiratory Research. 21, 1, p. 1-14 14 p., 128.

Research output: Contribution to journal › Article › peer-review

Open Access

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1 Citation (Scopus)

26 Downloads (Pure)

Bronchoprotective tolerance with indacaterol is not modified by concomitant tiotropium in persistent asthma

Jabbal, S., Manoharan, A. & Lipworth, B. J., Oct 2017, In: Clinical and Experimental Allergy. 47, 10, p. 1239-1245 7 p.

Research output: Contribution to journal › Article › peer-review

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5 Citations (Scopus)

199 Downloads (Pure)

Cardiopulmonary interactions with beta-blockers and inhaled therapy in COPD

Jabbal, S., Anderson, W., Short, P., Morrison, A., Manoharan, A. & Lipworth, B. J., Dec 2017, In: QJM : an International Journal of Medicine. 110, 12, p. 785-792 8 p.

Research output: Contribution to journal › Article › peer-review

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4 Citations (Scopus)

183 Downloads (Pure)

Comparative evaluation of nasal blood flow and airflow in the decongestant response to oxymetazoline

Vaidyanathan, S., Williamson, P. & Lipworth, B., Feb 2012, In: Annals of Allergy, Asthma & Immunology. 108, 2, p. 77-80 4 p.

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Comparison of the effect of beclometasone/formoterol in asthma patients after methacholine-induced bronchoconstriction: a non-inferiority study using metered dose versus dry powder inhaler

Singh, D., van den Berg, F., Leaker, B., Corradi, M., Jabbal, S., Collarini, S., Mongelli, V., Santoro, L., Piccinno, A., Biondaro, S. & Lipworth, B., Apr 2019, In: British Journal of Clinical Pharmacology. 85, 4, p. 729-736 21 p.

Research output: Contribution to journal › Article › peer-review

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2 Citations (Scopus)

69 Downloads (Pure)

Correction to: Beneft:Risk Profle of Budesonide in Obstructive Airways Disease

Tashkin, D. P., Lipworth, B. & Brattsand, R., Nov 2019, In: Drugs. 79, 17, p. 1911 1 p.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Does body mass index influence responsiveness to inhaled corticosteroids in persistent asthma?

Anderson, W. J. & Lipworth, B. J., Apr 2012, In: Annals of Allergy, Asthma & Immunology. 108, 4, p. 237-242 6 p.

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Don’t Forget about Facilitatory Effects of Corticosteroids on b ₂-Adrenoceptors in Acute Asthma

Lipworth, B., Chan, R. & Kuo, C. R., 15 Dec 2020, In: American Journal of Respiratory and Critical Care Medicine. 202, 12, p. 1743 1 p.

Research output: Contribution to journal › Article › peer-review

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Effects of Extra-Fine Inhaled and Oral Corticosteroids on Alveolar Nitric Oxide in COPD

Short, P. M., Williamson, P. A. & Lipworth, B. J., Aug 2012, In: Lung. 190, 4, p. 395-401 7 p.

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Effects of hydrocortisone on acute β-adrenoceptor blocker and histamine induced bronchoconstriction

Short, P. M., Williamson, P. A. & Lipworth, B. J., May 2012, In: British Journal of Clinical Pharmacology. 73, 5, p. 717-726 10 p.

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Effects of intranasal salmeterol and fluticasone given alone and in combination in persistent allergic rhinitis

Lipworth, B. J., Short, P., Burns, P. & Nair, A., Jan 2012, In: Annals of Allergy, Asthma & Immunology. 108, 1, p. 54-59 6 p.

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Effects of intravenous and oral β-blockade in persistent asthmatics controlled on inhaled corticosteroids

Short, P. M., Anderson, W. J., Williamson, P. A. & Lipworth, B. J., Feb 2014, In: Heart (British Cardiac Society). 100, 3, p. 219-223 5 p.

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19

Herold, T., Jurinovic, V., Arnreich, C., Lipworth, B. J., Hellmuth, J. C., von Bergwelt-Baildon, M., Klein, M. & Weinberger, T., Jul 2020, In: Journal of Allergy and Clinical Immunology. 146, 1, p. 128-136.e4 13 p.

Research output: Contribution to journal › Article › peer-review

132 Citations (Scopus)

Erratum to: Comparative lung bioavailability of fluticasone/salmeterol via a breath-actuated spacer and conventional plastic spacers

Nair, A., McKinlay, L., Williamson, P., Short, P., Burns, P. & Lipworth, B. J., Jun 2017, In: European Journal of Clinical Pharmacology. 73, 6, p. 793-793 1 p.

Research output: Contribution to journal › Article › peer-review

Fluticasone/Salmeterol Combination Confers Benefits in People With Asthma Who Smoke

Clearie, K. L., McKinlay, L., Williamson, P. A. & Lipworth, B. J., Feb 2012, In: Chest. 141, 2, p. 330-338 9 p.

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Glycopyrrolate/formoterol fumarate metered dose inhaler for maintenance-naïve patients with chronic obstructive pulmonary disease: a post-hoc analysis of the randomized PINNACLE trials

Zheng, J., Xu, J-F., Jenkins, M., Assam, P. N., Wang, L. & Lipworth, B. J., 12 Mar 2020, In: Respiratory Research. 21, 10 p., 69.

Research output: Contribution to journal › Article › peer-review

Open Access

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1 Citation (Scopus)

42 Downloads (Pure)

Glycopyrrolate/formoterol fumarate metered dose inhaler improves lung function versus monotherapies in GOLD category a patients with COPD: Pooled data from the phase III PINNACLE studies

Martinez, F. J., Rabe, K. F., Lipworth, B. J., Arora, S., Jenkins, M., Martin, U. J. & Reisner, C., 2020, In: International Journal of COPD. 15, p. 99-106 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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1 Citation (Scopus)

52 Downloads (Pure)

Impact of long-acting bronchodilators and exposure to inhaled corticosteroids on mortality in COPD: a real-life retrospective cohort study

Manoharan, A., Short, P. M., Anderson, W. J. & Lipworth, B. J., Oct 2014, In: Lung. 192, 5, p. 649-652 4 p.

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Impulse oscillometry bronchodilator response and asthma control

Kuo, C. R., Chan, R. & Lipworth, B., 31 Jul 2020, In: The Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journal › Article › peer-review

Inhaled corticosteroid dose-response in asthma: Should we measure inflammation?

Anderson, W. J., Short, P., Jabbal, S. & Lipworth, B., Feb 2017, In: Annals of Allergy, Asthma & Immunology. 118, 2, p. 179-185 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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7 Citations (Scopus)

178 Downloads (Pure)

Inhaled corticosteroid dose response using domiciliary exhaled nitric oxide in persistent asthma: the FENOtype trial

Anderson, W. J., Short, P., Williamson, P. A. & Lipworth, B. J., Dec 2012, In: Chest. 142, 6, p. 1553-61 9 p.

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Is a positive nasal lysine-aspirin challenge test associated with a more severe phenotype of chronic rhinosinusitis and asthma?

Vaidyanathan, S., Williamson, P. A. & Lipworth, B. J., 2012, In: American Journal of Rhinology & Allergy. 26, 3, p. E89-E93 5 p.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

I say IOS you say AOS: comparative bias in respiratory impedance measurements

Kuo, C., Jabbal, S. & Lipworth, B., Aug 2019, In: Lung. 197, 4, p. 473-481 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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4 Citations (Scopus)

124 Downloads (Pure)

Lack of clinically relevant differences between combination therapy and monotherapy in COPD

Lipworth, B. J., Apr 2014, In: European Respiratory Journal. 43, 4, p. 1204 1 p.

Research output: Contribution to journal › Article › peer-review

Making simple things complicated using anti-inflammatory reliever therapy

Lipworth, B., Kuo, C. R. & Chan, R., 30 Apr 2020, In: European Respiratory Journal. 55, 4, 2000267.

Research output: Contribution to journal › Article › peer-review

Pragmatic clinical perspective on biologics for severe refractory type 2 asthma

Chan, R., Kuo, C. R. & Lipworth, B., 13 Jul 2020, In: The Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Pragmatic evaluation of inhaled corticosteroid particle size formulations on asthma control

Kuo, C., Jabbal, S., Anderson, W. & Lipworth, B., 9 Oct 2019, In: Clinical and Experimental Allergy. 49, 10, p. 1321-1327 7 p.

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Open Access

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2 Citations (Scopus)

20 Downloads (Pure)

Proof of concept evaluation of trough airway hyper-responsiveness following regular racemic or levosalbutamol in genotype-stratified steroid-treated persistent asthmatic patients

Anderson, W. J., Short, P. M., Williamson, P. A., Morrison, A. E., Palmer, C., Tavendale, R. & Lipworth, B. J., 1 Jan 2014, In: Clinical Science. 126, 1, p. 75-83 9 p.

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Prospective Follow-Up of Novel Markers of Bone Turnover in Persistent Asthmatics Exposed to Low and High Doses of Inhaled Ciclesonide over 12 Months

Anderson, W. J., McFarlane, L. C. & Lipworth, B. J., Jun 2012, In: Journal of Clinical Endocrinology & Metabolism. 97, 6, p. 1929-1936 8 p.

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Randomized controlled trial of triple versus dual inhaler therapy on small airways in smoking asthmatics

Jabbal, S., Kuo, C. R. & Lipworth, B., Oct 2020, In: Clinical and Experimental Allergy. 50, 10, p. 1140-1147 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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1 Citation (Scopus)

70 Downloads (Pure)

Relationship of mannitol challenge to methacholine challenge and inflammatory markers in persistent asthmatics receiving inhaled corticosteroids

Anderson, W. J. & Lipworth, B. J., 2012, In: Lung. p. 1-9 9 p.

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Relationships between impulse oscillometry, spirometry and dyspnoea in COPD

Anderson, W. J. & Lipworth, B. J., 2012, In: Journal of the Royal College of Physicians of Edinburgh. 42, 2, p. 111-115 5 p.

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Respiratory effect of beta-blockers in people with asthma and cardiovascular disease: population-based nested case control study

Morales, D. R., Lipworth, B. J., Donnan, P. T., Jackson, C. & Guthrie, B., 27 Jan 2017, In: BMC Medicine. 15, 9 p., 18.

Research output: Contribution to journal › Article › peer-review

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34 Citations (Scopus)

333 Downloads (Pure)

Safety risks for patients with aspirin-exacerbated respiratory disease after acute exposure to selective nonsteroidal anti-inflammatory drugs and COX-2 inhibitors: meta-analysis of controlled clinical trials

Morales, D. R., Lipworth, B. J., Guthrie, B., Jackson, C., Donnan, P. T. & Santiago, V. H., Jul 2014, In: Journal of Allergy and Clinical Immunology. 134, 1, p. 40-45.e10 16 p.

Research output: Contribution to journal › Article › peer-review

44 Citations (Scopus)

Sensitivity of impulse oscillometry and spirometry in beta-blocker induced bronchoconstriction and beta-agonist bronchodilatation in asthma

Short, P., Williamson, P. A. & Lipworth, B. J., Dec 2012, In: Annals of Allergy, Asthma & Immunology. 109, 6, p. 412-5 4 p.

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Severe chronic allergic (and related) diseases: a uniform approach - A MeDALL - GA(2)LEN - ARIA position paper

Bousquet, J., Anto, J. M., Demoly, P., Schuenemann, H. J., Togias, A., Akdis, M., Auffray, C., Bachert, C., Bieber, T., Bousquet, P. J., Carlsen, K. H., Casale, T. B., Cruz, A. A., Keil, T., Carlsen, K. C. L., Maurer, M., Ohta, K., Papadopoulos, N. G., Rodriguez, M. R., Samolinski, B. & 31 others, Agache, I., Andrianarisoa, A., Ang, C. S., Annesi-Maesano, I., Ballester, F., Baena-Cagnani, C. E., Basagana, X., Bateman, E. D., Bel, E. H., Bedbrook, A., Beghe, B., Beji, M., Ben Kheder, A., Benet, M., Bennoor, K. S., Bergmann, K. C., Berrissoul, F., Jensen, C. B., Bleecker, E. R., Bonini, S., Boner, A. L., Boulet, L. P., Brightling, C. E., Brozek, J. L., Bush, A., Busse, W. W., Camargos, P. A. M., Canonica, G. W., Carr, W., Lipworth, B. & WHO Collaborating Ctr Asthma, 2012, In: International Archives of Allergy and Immunology. 158, 3, p. 216-231 16 p.

Research output: Contribution to journal › Article › peer-review

69 Citations (Scopus)