Find Research Outputs

Search results

• World Health Organization essential medicines lists: where are the drugs to treat neuropathic pain?

  Kamerman, P. R., Wadley, A. L., Davis, K. D., Hietaharju, A., Jain, P., Kopf, A., Meyer, A-C., Raja, S. N., Rice, A. S. C., Smith, B. H., Treede, R-D. & Wiffen, P. J., May 2015, In: Pain. 156, 5, p. 793-797 5 p.

  Research output: Contribution to journal › Article › peer-review
  23 Citations (Scopus)

• Variants associated with HHIP expression have sex-differential effects on lung function

  Smith, B. H., 1 Jun 2020, In: Wellcome Open Research. 5, p. 1-14 14 p., 111.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Hedgehog Proteins
  • Lung
  • Forced Expiratory Volume
  • Proteins
  • Polymorphism
  19 Downloads (Pure)

• Trends in gabapentinoid prescribing, co-prescribing of opioids and benzodiazepines, and associated deaths in Scotland

  Torrance, N., Veluchamy, A., Zhou, Y., Fletcher, E., Moir, E., Hebert, H., Donnan, P., Watson, J., Colvin, L. & Smith, B. H., Aug 2020, In: British Journal of Anaesthesia. 125, 2, p. 159-167 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Scotland
  • Benzodiazepines
  • Opioid Analgesics
  • Prescriptions
  • Pregabalin
  1 Citation (Scopus)

• Translating clinical trials into improved real-world management of pain: Convergence of translational, population-based and primary care research

  Gilron, I., Blyth, F. M. & Smith, B., Jan 2020, In: Pain. 161, 1, p. 36-42 7 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File
  18 Downloads (Pure)

• Towards a definition of refractory neuropathic pain for epidemiological research: an international Delphi survey of experts

  Smith, B. H., Torrance, N., Ferguson, J. A., Bennett, M. I., Serpell, M. G. & Dunn, K. M., 28 May 2012, In: BMC Neurology. 12, 29.

  Research output: Contribution to journal › Article › peer-review

  • Intractable Pain
  • Neuralgia
  • Consensus
  • Pain
  • Self-Examination
  26 Citations (Scopus)

• The National Pain Audit for specialist pain services in England and Wales 2010–2014

  Price, C., de C Williams, A. C., Smith, B. H. & Bottle, A., 1 Aug 2019, In: British Journal of Pain. 13, 3, p. 185-193 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Wales
  • England
  • Pain Clinics
  • Pain
  • Quality Improvement
  3 Citations (Scopus)

  185 Downloads (Pure)

• The impact of chronic musculoskeletal pain on physical activity in older adults: implications for self-management

  Martin, D. J., Anthony, G. B., Clarke, A., Jones, D., McNamee, P., Schofield, P. A. & Smith, B. H., 2012, In: Journal of Aging and Physical Activity. 20, Supplement, p. S294-S295 2 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• The IASP classification of chronic pain for ICD-11: Chronic neuropathic pain

  Scholz, J., Finnerup, N. B., Attal, N., Aziz, Q., Baron, R., Bennett, M. I., Benoliel, R., Cohen, M., Cruccu, G., Davis, K. D., Evers, S., First, M. B., Giamberardino, M. A., Hansson, P. T., Kaasa, S., Korwisi, B., Kosek, E., Lavandʼhomme, P., Nicholas, M., Nurmikko, T. J. & 13 others, Perrot, S., Raja, S. N., Rice, A. S. C., Rowbotham, M. C., Schug, S., Smipson, D. M., Smith, B., Svensson, P., Vlaeyen, J. W. S., Wang, S-J., Barke, A., Rief, W. & Treede, R-D., 1 Jan 2019, In: Pain. 160, 1, p. 53-59 7 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Neuralgia
  • International Classification of Diseases
  • Chronic Pain
  • Pain
  • Postherpetic Neuralgia
  78 Citations (Scopus)

  26 Downloads (Pure)

• The IASP classification of chronic pain for ICD-11: Applicability in Primary Care

  Smith, B., Fors, E. A., Korwisi, B., Barke, A., Cameron, P., Colvin, L., Richardson, C., Rief, W. & Treede, R-D., 1 Jan 2019, In: Pain. 160, 1, p. 83-87 5 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • International Classification of Diseases
  • Chronic Pain
  • Primary Health Care
  • Forensic Anthropology
  • Delivery of Health Care
  18 Citations (Scopus)

  24 Downloads (Pure)

• The genetics of neuropathic pain from model organisms to clinical application

  Calvo, M., Davies, A. J., Hebert, H., Weir, G., Chesler, E. J., Finnerup, N. B., Smith, B. H., Neely, G., Costigan, M. & Bennett, D. L., 20 Nov 2019, In: Neuron. 104, 4, p. 637-653 17 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Neuralgia
  • Genetic Techniques
  • Pain Clinics
  • Nervous System Trauma
  • Clustered Regularly Interspaced Short Palindromic Repeats
  9 Citations (Scopus)

  124 Downloads (Pure)

• Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

  Tin, A., Marten, J., Halperin Kuhns, V. L., Li, Y., Wuttke, M., Kirsten, H., Sieber, K. B., Qiu, C., Gorski, M., Yu, Z., Giri, A., Sveinbjornsson, G., Li, M., Chu, A. Y., Hoppmann, A., O'Connor, L. J., Prins, B., Nutile, T., Noce, D., Akiyama, M. & 31 others, Cocca, M., Ghasemi, S., van der Most, P. J., Horn, K., Xu, Y., Fuchsberger, C., Sedaghat, S., Afaq, S., Amin, N., Ärnlöv, J., Bakker, S. J. L., Bansal, N., Baptista, D., Bergmann, S., Biggs, M. L., Biino, G., Boerwinkle, E., Bottinger, E. P., Boutin, T. S., Brumat, M., Burkhardt, R., Campana, E., Campbell, A., Campbell, H., Carroll, R. J., Catamo, E., Chambers, J. C., Ciullo, M., Concas, M. P., Smith, B. H. & Köttgen, A., Oct 2019, In: Nature Genetics. 51, 10, p. 1459–1474 22 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Uric Acid
  • Gout
  • Serum
  • Genes
  • urate transporter
  30 Citations (Scopus)

  41 Downloads (Pure)

• Substance misuse of gabapentin

  Smith, B. H., Higgins, C., Baldacchino, A., Kidd, B. & Bannister, J., Aug 2012, In: British Journal of General Practice. 62, 601, p. 406-7 2 p.

  Research output: Contribution to journal › Article › peer-review
  40 Citations (Scopus)

• Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose

  Wu, P., Rybin, D., Bielak, L. F., Feitosa, M. F., Franceschini, N., Li, Y., Lu, Y., Marten, J., Musani, S. K., Noordam, R., Raghavan, S., Rose, L. M., Schwander, K., Smith, A. V., Tajuddin, S. M., Vojinovic, D., Amin, N., Arnett, D. K., Bottinger, E. P., Demirkan, A. & 38 others, Florez, J. C., Ghanbari, M., Harris, T. B., Launer, L. J., Liu, J., Liu, J., Mook-Kanamori, D. O., Murray, A. D., Nalls, M. A., Peyser, P. A., Uitterlinden, A. G., Voortman, T., Bouchard, C., Chasman, D., Correa, A., de Mutsert, R., Evans, M. K., Gudnason, V., Hayward, C., Kao, L., Kardia, S. L. R., Kooperberg, C., Loos, R. J. F., Province, M. M., Rankinen, T., Redline, S., Ridker, P. M., Rotter, J. I., Siscovick, D., Smith, B. H., van Duijn, C., Zonderman, A. B., Rao, D. C., Wilson, J. G., Dupuis, J., Meigs, J. B., Liu, C-T. & Vassy, J. L., 7 May 2020, In: PLoS ONE. 15, 5, p. 1-17 17 p., e0230815.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • noninsulin-dependent diabetes mellitus
  • Medical problems
  • fasting
  • Fasting
  • Type 2 Diabetes Mellitus
  2 Citations (Scopus)

  24 Downloads (Pure)

• Sex-differences in the metabolic health of offspring of parents with diabetes: a record-linkage study

  Aldhous, M. C., Reynolds, R. M., Campbell, A., Linksted, P., Lindsay, R. S., Smith, B. H., Seckl, J. R., Porteous, D. J., Norman, J. E. & Generation Scotland, 26 Aug 2015, In: PLoS ONE. 10, 8, 18 p., e0134883.

  Research output: Contribution to journal › Article › peer-review

  • records (publications)
  • Medical problems
  • diabetes
  • gender differences
  • Sex Characteristics
  10 Citations (Scopus)

• Sex-and Age-Specific Genetic Analysis of Chronic Back Pain

  Freidin, M. B., Tsepilov, Y. A., Stanaway, I. B., Meng, W., Hayward, C., Smith, B. H., Khoury, S., Parisien, M., Bortsov, A., Diatchenko, L., Børte, S., Winsvold, B. S., Brumpton, B. M., Zwart, J-A., Aulchenko, Y. S., Suri, P. & Williams, F. M. K., 5 Oct 2020, In: Pain.

  Research output: Contribution to journal › Article › peer-review

  • Back Pain
  • Chronic Pain
  • Single Nucleotide Polymorphism
  • Chromosomes, Human, Pair 10
  • Intervertebral Disc Degeneration

• Reply to Henningsen et al.

  Rief, W., Korwisi, B., Nicholas, M., Vlaeyen, J. W. S., Smith, B. H., First, M. B., Kosek, E., Barke, A. & Treede, R-D., Jul 2019, In: Pain. 160, 7, p. 1683-1685 3 p.

  Research output: Contribution to journal › Letter › peer-review

• Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

  T2D-Genes Consortium, The MAGIC Investigators, CHD Exome+ Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, ReproGen Consortium, Justice, A. E., Karaderi, T., Highland, H. M., Young, K. L., Graff, M., Lu, Y., Turcot, V., Auer, P. L., Fine, R. S., Guo, X., Schurmann, C., Lempradl, A. & 40 others, Marouli, E., Mahajan, A., Winkler, T. W., Locke, A. E., Medina-Gomez, C., Esko, T., Vedantam, S., Giri, A., Lo, K. S., Alfred, T., Mudgal, P., Ng, M. C. Y., Heard-Costa, N. L., Feitosa, M. F., Manning, A. K., Willems, S. M., Sivapalaratnam, S., Abecasis, G., Alam, D. S., Allison, M., Amouyel, P., Arzumanyan, Z., Balkau, B., Bastarache, L., Bergmann, S., Bielak, L. F., Blüher, M., Boehnke, M., Boeing, H., Boerwinkle, E., Böger, C. A., Bork-Jensen, J., Evangelou, E., Li, J., Morris, A. P., Smith, B. H., Smith, J. A., Wood, A. R., North, K. E. & Lindgren, C. M., Mar 2019, In: Nature Genetics. 51, 3, p. 452-469 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Body Fat Distribution
  • Homeostasis
  • Lipids
  • Fats
  • White Adipose Tissue
  21 Citations (Scopus)

  266 Downloads (Pure)

• Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis

  Finnerup, N. B., Attal, N., Haroutounian, S., McNicol, E., Baron, R., Dworkin, R. H., Gilron, I., Haanpää, M., Hansson, P., Jensen, T. S., Kamerman, P. R., Lund, K., Moore, A., Raja, S. N., Rice, A. S. C., Rowbotham, M., Sena, E., Siddall, P., Smith, B. H. & Wallace, M., Feb 2015, In: Lancet Neurology. 14, 2, p. 162-173 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuralgia
  • Meta-Analysis
  • Systematic Reviews
  • Drug Therapy
  • Tramadol
  1377 Citations (Scopus)

• Pharmacist-led management of chronic pain in primary care: costs and benefits in a pilot randomised controlled trial

  Neilson, A. R., Bruhn, H., Bond, C. M., Elliott, A. M., Smith, B. H., Hannaford, P. C., Holland, R., Lee, A. J., Watson, M., Wright, D. & McNamee, P., 1 Apr 2015, In: BMJ Open. 5, 4, 11 p., e006874.

  Research output: Contribution to journal › Article › peer-review

  • Pharmacists
  • Chronic Pain
  • Cost-Benefit Analysis
  • Primary Health Care
  • Quality-Adjusted Life Years
  13 Citations (Scopus)

• Perioperative management of patients with suspected or confirmed COVID-19: review and recommendations for perioperative management from a retrospective cohort study

  Zheng, H., Hébert, H. L., Chatziperi, A., Meng, W., Smith, B. H., Yan, J., Zhou, Z., Zhang, X., Luo, A., Wang, L., Zhu, W., Hu, J. & Colvin, L. A., Dec 2020, In: British Journal of Anaesthesia. 125, 6, p. 895-911 17 p.

  Research output: Contribution to journal › Review article › peer-review

  • Coronavirus
  • Cohort Studies
  • Retrospective Studies
  • Personal Protective Equipment
  • Health Personnel

• PALS: peer support for community dwelling older people with chronic low back pain: a feasibility and acceptability study

  Cooper, K., Schofield, P., Smith, B. H. & Klein, S., Mar 2020, In: Physiotherapy (United Kingdom). 106, p. 154-162 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Feasibility Studies
  • Independent Living
  • Low Back Pain
  • Volunteers
  • Outcome Assessment (Health Care)
  2 Citations (Scopus)

  136 Downloads (Pure)

• Out of Hours: My personal diagnostic delay

  Smith, B. H., 1 Apr 2015, In: British Journal of General Practice. 65, 633, p. 200 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • Physicians

• Opioid prescribing is rising in many countries

  Smith, B. H., Fletcher, E. H. & Colvin, L. A., 17 Oct 2019, In: BMJ. 367, p. 1-2 2 p., l5823.

  Research output: Contribution to journal › Editorial › peer-review

  • Chronic Pain
  • Opioid Analgesics
  4 Citations (Scopus)

• New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

  Understanding Society Scientific Group, Shrine, N., Guyatt, A. L., Erzurumluoglu, A. M., Jackson, V. E., Hobbs, B. D., Melbourne, C. A., Batini, C., Fawcett, K. A., Song, K., Sakornsakolpat, P., Li, X., Boxall, R., Reeve, N. F., Obeidat, M., Zhao, J. H., Wielscher, M., Weiss, S., Kentistou, K. A., Cook, J. P. & 33 others, Sun, B. B., Zhou, J., Hui, J., Karrasch, S., Imboden, M., Harris, S. E., Marten, J., Enroth, S., Kerr, S. M., Surakka, I., Vitart, V., Lehtimäki, T., Allen, R. J., Bakke, P. S., Beaty, T. H., Bleecker, E. R., Bossé, Y., Brandsma, C-A., Chen, Z., Crapo, J. D., Danesh, J., DeMeo, D. L., Dudbridge, F., Ewert, R., Gieger, C., Gulsvik, A., Hansell, A. L., Hao, K., Hoffman, J. D., Hokanson, J. E., Smith, B. H., Tobin, M. D. & Wain, L. V., Mar 2019, In: Nature Genetics. 51, 3, p. 481-493 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Chronic Obstructive Pulmonary Disease
  • Lung
  • Smokers
  • Genome-Wide Association Study
  • Mortality
  52 Citations (Scopus)

  397 Downloads (Pure)

• Neuropathic pain phenotyping by international consensus (NeuroPPIC) for genetic studies: a NeuPSIG systematic review, Delphi survey, and expert panel recommendations

  van Hecke, O., Kamerman, P. R., Attal, N., Baron, R., Bjornsdottir, G., Bennett, D. L. H., Bennett, M. I., Bouhassira, D., Diatchenko, L., Freeman, R., Freynhagen, R., Haanpää, M., Jensen, T. S., Raja, S. N., Rice, A. S. C., Seltzer, Z., Thorgeirsson, T. E., Yarnitsky, D. & Smith, B. H., Nov 2015, In: Pain. 156, 11, p. 2337-2353 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuralgia
  • Consensus
  • Systematic Reviews
  • Phenotype
  • Pain
  35 Citations (Scopus)

• Neuropathic pain in the community: prevalence, impact and risk factors

  Smith, B. H., Hebert, H. L. & Veluchamy, A., 1 Sep 2020, In: Pain. 161, Supplement 1, p. S127-S137 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuralgia
  • Primary Health Care
  • Direction compound
  • Psychology
  • Quality of Life

• Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

  Ntalla, I., Weng, L., Cartwright, J. H., Hall, A. W., Sveinbjornsson, G., Tucker, N. R., Choi, S. H., Chaffin, M. D., Roselli, C., Barnes, M. R., Mifsud, B., Warren, H. R., Hayward, C., Marten, J., Cranley, J. J., Concas, M. P., Gasparini, P., Boutin, T., Kolcic, I., Polasek, O. & 167 others, Rudan, I., Araujo, N. M., Lima-costa, M. F., Ribeiro, A. L. P., Souza, R. P., Tarazona-santos, E., Giedraitis, V., Ingelsson, E., Mahajan, A., Morris, A. P., Del Greco M, F., Foco, L., Gögele, M., Hicks, A. A., Cook, J. P., Lind, L., Lindgren, C. M., Sundström, J., Nelson, C. P., Riaz, M. B., Samani, N. J., Sinagra, G., Ulivi, S., Kähönen, M., Mishra, P. P., Mononen, N., Nikus, K., Caulfield, M. J., Dominiczak, A., Padmanabhan, S., Montasser, M. E., O’connell, J. R., Ryan, K., Shuldiner, A. R., Aeschbacher, S., Conen, D., Risch, L., Thériault, S., Hutri-kähönen, N., Lehtimäki, T., Lyytikäinen, L., Raitakari, O. T., Barnes, C. L. K., Campbell, H., Joshi, P. K., Wilson, J. F., Isaacs, A., Kors, J. A., Van Duijn, C. M., Huang, P. L., Gudnason, V., Harris, T. B., Launer, L. J., Smith, A. V., Bottinger, E. P., Loos, R. J. F., Nadkarni, G. N., Preuss, M. H., Correa, A., Mei, H., Wilson, J., Meitinger, T., Müller-nurasyid, M., Peters, A., Waldenberger, M., Mangino, M., Spector, T. D., Rienstra, M., Van De Vegte, Y. J., Van Der Harst, P., Verweij, N., Kääb, S., Schramm, K., Sinner, M. F., Strauch, K., Cutler, M. J., Fatkin, D., London, B., Olesen, M., Roden, D. M., Benjamin Shoemaker, M., Gustav Smith, J., Biggs, M. L., Bis, J. C., Brody, J. A., Psaty, B. M., Rice, K., Sotoodehnia, N., De Grandi, A., Fuchsberger, C., Pattaro, C., Pramstaller, P. P., Ford, I., Wouter Jukema, J., Macfarlane, P. W., Trompet, S., Dörr, M., Felix, S. B., Völker, U., Weiss, S., Havulinna, A. S., Jula, A., Sääksjärvi, K., Salomaa, V., Guo, X., Heckbert, S. R., Lin, H. J., Rotter, J. I., Taylor, K. D., Yao, J., De Mutsert, R., Maan, A. C., Mook-kanamori, D. O., Noordam, R., Cucca, F., Ding, J., Lakatta, E. G., Qian, Y., Tarasov, K. V., Levy, D., Lin, H., Newton-cheh, C. H., Lunetta, K. L., Murray, A. D., Porteous, D. J., Smith, B. H., Stricker, B. H., Uitterlinden, A., Van Den Berg, M. E., Haessler, J., Jackson, R. D., Kooperberg, C., Peters, U., Reiner, A. P., Whitsel, E. A., Alonso, A., Arking, D. E., Boerwinkle, E., Ehret, G. B., Soliman, E. Z., Avery, C. L., Gogarten, S. M., Kerr, K. F., Laurie, C. C., Seyerle, A. A., Stilp, A., Assa, S., Abdullah Said, M., Yldau Van Der Ende, M., Lambiase, P. D., Orini, M., Ramirez, J., Van Duijvenboden, S., Arnar, D. O., Gudbjartsson, D. F., Holm, H., Sulem, P., Thorleifsson, G., Thorolfsdottir, R. B., Thorsteinsdottir, U., Benjamin, E. J., Tinker, A., Stefansson, K., Ellinor, P. T., Jamshidi, Y., Lubitz, S. A. & Munroe, P. B., 21 May 2020, In: Nature Communications. 11, 1, 12 p., 2542.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • loci
  • Genome-Wide Association Study
  • Genes
  • intervals
  • genes
  2 Citations (Scopus)

  30 Downloads (Pure)

• Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

  InterAct Consortium, LifeLines Cohort Study, de Vries, P. S., Brown, M. R., Bentley, A. R., Sung, Y. J., Winkler, T. W., Ntalla, I., Schwander, K., Kraja, A. T., Guo, X., Franceschini, N., Cheng, C-Y., Sim, X., Vojinovic, D., Huffman, J. E., Musani, S. K., Li, C., Feitosa, M. F., Richard, M. A. & 34 others, Noordam, R., Aschard, H., Bartz, T. M., Bielak, L. F., Deng, X., Dorajoo, R., Lohman, K. K., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Evangelou, E., Graff, M., Alver, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Goel, A., Hagemeijer, Y., Harris, S. E., Hartwig, F. P., He, M., Horimoto, A. R. V. R., Hsu, F-C., Jackson, A. U., Kasturiratne, A., Komulainen, P., Connell, J. M., Smith, B. H., Rao, D. C. & Morrison, A. C., 1 Jun 2019, In: American Journal of Epidemiology. 188, 6, p. 1033-1054 22 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Genome-Wide Association Study
  • Alcohols
  • Lipids
  • APOBEC-1 Deaminase
  • Vascular Endothelial Growth Factor B
  16 Citations (Scopus)

  135 Downloads (Pure)

• Mosaic structural variation in children with developmental disorders

  King, D. A., Jones, W. D., Crow, Y. J., Dominiczak, A. F., Foster, N. A., Gaunt, T. R., Harris, J., Hellens, S. W., Homfray, T., Innes, J., Jones, E. A., Joss, S., Kulkarni, A., Mansour, S., Morris, A. D., Parker, M. J., Porteous, D. J., Shihab, H. A., Smith, B. H., Tatton-Brown, K. & 9 others, Tolmie, J. L., Trzaskowski, M., Vasudevan, P. C., Wakeling, E., Wright, M., Plomin, R., Timpson, N. J., Hurles, M. E. & Deciphering Developmental Disorders (DDD) Study, 15 May 2015, In: Human Molecular Genetics. 24, 10, p. 2733-2745 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Mosaicism
  • Child
  • Chimerism
  • Loss of Heterozygosity
  • Genetic Testing
  32 Citations (Scopus)

  14 Downloads (Pure)

• Major depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass index

  Clarke, T. K., Hall, L. S., Fernandez-Pujals, A. M., MacIntyre, D. J., Thomson, P., Hayward, C., Smith, B. H., Padmanabhan, S., Hocking, L. J., Deary, I. J., Porteous, D. J. & McIntosh, A. M., 30 Jun 2015, In: Translational Psychiatry. 5, 6, p. 1-6 6 p., e592.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Major Depressive Disorder
  • Body Mass Index
  • Obesity
  • Psychology
  • Neuroticism
  16 Citations (Scopus)

  173 Downloads (Pure)

• Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

  UK10K Consortium, 21 Jan 2019, In: Nature Communications. 10, 1, 357.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • circumferences
  • Head
  • Genetic Variation
  • Genetic Models
  • Human Development
  9 Citations (Scopus)

  113 Downloads (Pure)

• Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

  Wessel, J., Chu, A. Y., Willems, S. M., Wang, S., Yaghootkar, H., Brody, J. A., Dauriz, M., Hivert, M-F., Raghavan, S., Lipovich, L., Hidalgo, B., Fox, K., Huffman, J. E., An, P., Lu, Y., Rasmussen-Torvik, L. J., Grarup, N., Ehm, M. G., Li, L., Baldridge, A. S. & 31 others, Stančáková, A., Abrol, R., Besse, C., Boland, A., Bork-Jensen, J., Fornage, M., Freitag, D. F., Garcia, M. E., Guo, X., Hara, K., Isaacs, A., Jakobsdottir, J., Lange, L. A., Layton, J. C., Li, M., Hua Zhao, J., Meidtner, K., Morrison, A. C., Nalls, M. A., Peters, M. J., Sabater-Lleal, M., Schurmann, C., Silveira, A., Smith, A. V., Southam, L., Stoiber, M. H., Strawbridge, R. J., Taylor, K. D., Varga, T. V., Smith, B. H. & EPIC-InterAct Consortium, 29 Jan 2015, In: Nature Communications. 6, 16 p., 5897.

  Research output: Contribution to journal › Article › peer-review

  • fasting
  • Exome
  • glucose
  • Medical problems
  • insulin
  111 Citations (Scopus)

• Large-scale discovery of novel genetic causes of developmental disorders

  Deciphering Developmental Disorders (DDD) Study, 12 Mar 2015, In: Nature. 519, 7542, p. 223-228 6 p.

  Research output: Contribution to journal › Letter › peer-review

  • Inborn Genetic Diseases
  • Child
  • Exome
  • Genes
  • Missense Mutation
  504 Citations (Scopus)

• Insulin resistance: Genetic associations with depression and cognition in population based cohorts

  Frangou, S., Shirali, M., Adams, M. J., Howard, D. M., Gibson, J., Hall, L. S., Smith, B. H., Padmanabhan, S., Murray, A. D., Porteous, D. J., Haley, C. S., Deary, I. J., Clarke, T-K. & McIntosh, A. M., Jun 2019, In: Experimental Neurology. 316, p. 20-26 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Insulin Resistance
  • Cognition
  • Depression
  • Population
  • Intelligence
  1 Citation (Scopus)

  123 Downloads (Pure)

• Implementation of Patient-Reported Outcomes (PROMs) from specialist pain clinics in England and Wales: experience from a nationwide study

  Price, C. M., C. de C. Williams, A., Smith, B. H. & Bottle, A., 1 Aug 2019, In: European Journal of Pain. 23, 7, p. 1368-1377 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pain Clinics
  • Wales
  • Patient Reported Outcome Measures
  • England
  • Quality of Life
  1 Citation (Scopus)

  25 Downloads (Pure)

• Impact of sex and age on respiratory support and length of hospital stay among 1792 patients with COVID-19 in Wuhan, China

  Zheng, H., Tan, J., Zhang, X., Luo, A., Wang, L., Zhu, W., Hebert, H. L., Meng, W., Smith, B. H., Colvin, L. A. & Hu, J., 1 Oct 2020, In: British Journal of Anaesthesia. 125, 4, p. E378-E380 3 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Citation (Scopus)

• "I feel so stupid because I can't give a proper answer..." How older adults describe chronic pain: a qualitative study

  Clarke, A., Anthony, G., Gray, D., Jones, D., McNamee, P., Schofield, P., Smith, B. H. & Martin, D., 2012, In: BMC Geriatrics. 12, 1, 78.

  Research output: Contribution to journal › Article › peer-review

  • Chronic Pain
  • Pain
  • Metaphor
  • Interviews
  • Scotland
  16 Citations (Scopus)

• Heritability of chronic pain in 2195 extended families

  Hocking, L. J., Morris, A. D., Dominiczak, A. F., Porteous, D. J., Smith, B. H. & Generation Scotland, Aug 2012, In: European Journal of Pain. 16, 7, p. 1053-1063 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Chronic Pain
  • Scotland
  • Family Health
  • Occupations
  • Social Adjustment
  45 Citations (Scopus)

• Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

  Morris, R. W., Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Åsvold, B. O., Elvestad Gabrielsen, M., Campbell, A., Marioni, R., Kumari, M., Korhonen, T., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. V. S., Treur, J. L., Willemsen, G. & 42 others, Dale, C., Wannamethee, S. G., Lahti, J., Palotie, A., Räikkönen, K., McConnachie, A., Padmanabhan, S., Wong, A., Dalgård, C., Paternoster, L., Ben-Shlomo, Y., Tyrrell, J., Horwood, J., Fergusson, D. M., Kennedy, M. A., Nohr, E. A., Christiansen, L., Kyvik, K. O., Kuh, D., Watt, G., Eriksson, J. G., Whincup, P. H., Vink, J. M., Boomsma, D. I., Davey Smith, G., Lawlor, D., Linneberg, A., Ford, I., Jukema, J. W., Power, C., Hyppönen, E., Jarvelin, M-R., Preisig, M., Borodulin, K., Kaprio, J., Kivimaki, M., Smith, B. H., Hayward, C., Romundstad, P. R., Sørensen, T. I. A., Munafò, M. R. & Sattar, N., 11 Aug 2015, In: BMJ Open. 5, 8, 12 p., e008808.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Mendelian Randomization Analysis
  • Waist Circumference
  • Tobacco
  • Smokers
  • Meta-Analysis
  27 Citations (Scopus)

  118 Downloads (Pure)

• Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank

  Meng, W., Adams, M. J., Palmer, C. N. A., 23andMe Research Team, Shi, J., Auton, A., Ryan, K. A., Jordan, J. M., Mitchell, B. D., Jackson, R. D., Yau, M. S., McIntosh, A. M. & Smith, B. H., 28 Aug 2019, In: Communications Biology. 2, p. 1-8 8 p., 321.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • knees
  • genome-wide association study
  • osteoarthritis
  • Genome-Wide Association Study
  • pain
  7 Citations (Scopus)

  121 Downloads (Pure)

• Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP

  Wigmore, E. M., Hafferty, J. D., Hall, L. S., Howard, D. M., Clarke, T-K., Fabbri, C., Lewis, C. M., Uher, R., Navrady, L., Adams, M. J., Zeng, Y., Campbell, A., Gibson, J., Thomson, P. A., Hayward, C., Smith, B., Hocking, L. J., Padmanabhan, S., Deary, I. J., Porteous, D. J. & 4 others, Mors, O., Mattheisen, M., Nicodemus, K. K. & McIntosh, A. M., Apr 2020, In: Pharmacogenomics Journal. 20, p. 329-341 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Genome-Wide Association Study
  • Antidepressive Agents
  • Health Services
  • Prescriptions
  • Meta-Analysis
  14 Citations (Scopus)

  160 Downloads (Pure)

• Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility

  GenoMEL Consortium, Q-MEGA and QTWIN Investigators, ATHENS Melanoma Study Group, 23andMe, The SDH Study Group, IBD Investigators, Essen-Heidelberg Investigators, AMFS Investigators, MelaNostrum Consortium, Landi, M. T., Bishop, D. T., MacGregor, S., Machiela, M. J., Stratigos, A. J., Ghiorzo, P., Brossard, M., Calista, D., Choi, J., Fargnoli, M. C., Zhang, T. & 45 others, Rodolfo, M., Trower, A. J., Menin, C., Martinez, J., Hadjisavvas, A., Song, L., Stefanaki, I., Scolyer, R., Yang, R., Goldstein, A. M., Potrony, M., Kypreou, K. P., Pastorino, L., Queirolo, P., Pellegrini, C., Cattaneo, L., Zawistowski, M., Gimenez-Xavier, P., Rodriguez, A., Elefanti, L., Manoukian, S., Rivoltini, L., Smith, B. H., Loizidou, M. A., Del Regno, L., Massi, D., Mandala, M., Khosrotehrani, K., Akslen, L. A., Amos, C. I., Andresen, P. A., Avril, M-F., Azizi, E., Soyer, H. P., Bataille, V., Dalmasso, B., Bowdler, L. M., Burdon, K. P., Chen, W. V., Codd, V., Craig, J. E., Harris, J., Shi, J., Iles, M. M. & Law, M. H., May 2020, In: Nature Genetics. 52, 5, p. 494-504 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Genome-Wide Association Study
  • Melanoma
  • Meta-Analysis
  • Phenotype
  • Skin
  4 Citations (Scopus)

  442 Downloads (Pure)

• Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

  23andMe Research Team, Karlsson Linnér, R., Biroli, P., Kong, E., Meddens, S. F. W., Wedow, R., Fontana, M. A., Lebreton, M., Tino, S. P., Abdellaoui, A., Hammerschlag, A. R., Nivard, M. G., Okbay, A., Rietveld, C. A., Timshel, P. N., Trzaskowski, M., Vlaming, R. D., Zünd, C. L., Bao, Y., Buzdugan, L. & 22 others, Caplin, A. H., Chen, C. Y., Eibich, P., Fontanillas, P., Gonzalez, J. R., Joshi, P. K., Karhunen, V., Kleinman, A., Levin, R. Z., Lill, C. M., Meddens, G. A., Muntané, G., Sanchez-Roige, S., Rooij, F. J. V., Taskesen, E., Wu, Y., Zhang, F., Auton, A., Boardman, J. D., Clark, D. W., Conlin, A. & Beauchamp, J. P., 2019, In: Nature Genetics. 51, 2, p. 245-257 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Genetic Loci
  • Genome-Wide Association Study
  • Single Nucleotide Polymorphism
  • Driving Under the Influence
  • Computational Biology
  74 Citations (Scopus)

• Genetic variation in hyperpolarization-activated cyclic nucleotide-gated channels and its relationship with neuroticism, cognition and risk of depression

  McIntosh, A. M., Simen, A. A., Evans, K. L., Hall, J., MacIntyre, D. J., Blackwood, D., Morris, A. D., Smith, B. H., Dominiczak, A., Porteous, D., Deary, I. J. & Thomson, P. A., 2012, In: Frontiers in Genetics. 3, 00116.

  Research output: Contribution to journal › Article › peer-review

  • Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
  • Neuroticism
  • Genetic Variation
  • Cognition
  • Depression
  6 Citations (Scopus)

• Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

  Understanding Society Scientific Group, Sakornsakolpat, P., Prokopenko, D., Lamontagne, M., Reeve, N. F., Guyatt, A. L., Jackson, V. E., Shrine, N., Qiao, D., Bartz, T. M., Kim, D. K., Lee, M. K., Latourelle, J. C., Li, X., Morrow, J. D., Obeidat, M., Wyss, A. B., Bakke, P., Barr, R. G., Beaty, T. H. & 35 others, Belinsky, S. A., Brusselle, G. G., Crapo, J. D., de Jong, K., DeMeo, D. L., Fingerlin, T. E., Gharib, S. A., Gulsvik, A., Hall, I. P., Hokanson, J. E., Kim, W. J., Lomas, D. A., London, S. J., Meyers, D. A., O’Connor, G. T., Rennard, S. I., Schwartz, D. A., Sliwinski, P., Sparrow, D., Strachan, D. P., Tal-Singer, R., Tesfaigzi, Y., Vestbo, J., Vonk, J. M., Yim, J. J., Zhou, X., Bossé, Y., Manichaikul, A., Lahousse, L., Silverman, E. K., Boezen, H. M., Wain, L. V., Tobin, M. D., Hobbs, B. D. & Cho, M. H., 1 Mar 2019, In: Nature Genetics. 51, 3, p. 494-505 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Chronic Obstructive Pulmonary Disease
  • Phenotype
  • Genetic Loci
  • Lung
  • Genetic Heterogeneity
  48 Citations (Scopus)

• Genetic correlations between pain phenotypes and depression and neuroticism

  Meng, W., Adams, M. J., Reel, P., Rajendrakumar, A., Huang, Y., Deary, I. J., Palmer, C. N. A., McIntosh, A. M. & Smith, B. H., Mar 2020, In: European Journal of Human Genetics. 28, p. 358-366 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Neuroticism
  • Depression
  • Phenotype
  • Pain
  • Linkage Disequilibrium
  3 Citations (Scopus)

  96 Downloads (Pure)

• Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

  Clarke, T-K., Adams, M. J., Howard, D. M., Xia, C., Davies, G., Hayward, C., Campbell, A., Padmanabhan, S., Smith, B., Murray, A., Porteous, D., Deary, I. J. & McIntosh, A. M., 25 Nov 2019, In: Molecular Psychiatry. 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Alcohols
  • Smoking
  • Population
  • Single Nucleotide Polymorphism
  • Mating Factor
  1 Citation (Scopus)

  65 Downloads (Pure)

• Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

  van Leeuwen, E. M., Huffman, J. E., Bis, J. C., Isaacs, A., Mulder, M., Sabo, A., Smith, A. V., Demissie, S., Manichaikul, A., Brody, J. A., Feitosa, M. F., Duan, Q., Schraut, K. E., Navarro, P., van Vliet-Ostaptchouk, J. V., Zhu, G., Mbarek, H., Trompet, S., Verweij, N., Lyytikäinen, L-P. & 31 others, Deelen, J., Nolte, I. M., van der Laan, S. W., Davies, G., Vermeij-Verdoold, A. J., van Oosterhout, A. A., Vergeer-Drop, J. M., Arking, D. E., Trochet, H., Medina-Gomez, C., Rivadeneira, F., Uitterlinden, A. G., Dehghan, A., Franco, O. H., Sijbrands, E. J. G., Hofman, A., White, C. C., Mychaleckyj, J. C., Peloso, G. M., Swertz, M. A., Willemsen, G., de Geus, E. J. C., Milaneschi, Y., Penninx, B. W., Ford, I., Buckley, B. M., de Craen, A. J., Starr, J. M., Deary, I. J., Smith, B. H. & Generation Scotland, 2015, In: NPJ Aging and Mechanisms of Disease. 1, p. 1-9 9 p., 15011.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cholesterol Ester Transfer Proteins
  • Meta-Analysis
  • Genome
  • Particle Size
  • Longevity
  3 Citations (Scopus)

  135 Downloads (Pure)

• Factors associated with unscheduled care use by cancer decedents: a systematic review with narrative synthesis

  Mills, S. E. E., Geneen, L. J., Buchanan, D., Guthrie, B. & Smith, B. H., 13 Oct 2020, In: BMJ Supportive and Palliative Care. 21 p., 002410.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Systematic Reviews
  • Neoplasms
  • Palliative Care
  • Databases
  • Policy Making
  1 Citation (Scopus)

  129 Downloads (Pure)

• Factors affecting use of unscheduled care for people with advanced cancer: a retrospective cohort study in Scotland

  Mills, S., Buchanan, D., Guthrie, B., Donnan, P. & Smith, B., Dec 2019, In: British Journal of General Practice. 69, 689, p. e860-e868 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Scotland
  • Cohort Studies
  • Retrospective Studies
  • Neoplasms
  • Public Health
  1 Citation (Scopus)

  72 Downloads (Pure)