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Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P-3-dependent mechanisms leading to resistance to PDK1 inhibitors
Najafov, A., Shpiro, N. & Alessi, D. R., Dec 2012, In: Biochemical Journal. 448, 2, p. 285-295 11 p.Research output: Contribution to journal › Article › peer-review
47 Citations (Scopus) -
AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11
Piscitello, D., Varshney, D., Lilla, S., Vizioli, M. G., Reid, C., Gorbunova, V., Seluanov, A., Gillespie, D. A. & Adams, P. D., 25 Jan 2018, In: Oncogene. 37, 4, p. 427-438 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)211 Downloads (Pure) -
ALADIN is Required for the Production of Fertile Mouse Oocytes
Carvalhal, S., Stevense, M., Koehler, K., Naumann, R., Huebner, A., Jessberger, R. & Griffis, E. R., 17 Sep 2017, In: Molecular Biology of the Cell. 28, 19, p. 2470-2478 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)168 Downloads (Pure) -
A Land of Opportunity? The Assimilation of Scottish Migrants in England, 1603-c.1762
Brown, K. M. & Kennedy, A., 1 Oct 2018, In: Journal of British Studies. 57, 4, p. 709-735 27 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)180 Downloads (Pure) -
A Large Polysaccharide Produced by Helicobacter hepaticus Induces an Anti-inflammatory Gene Signature in Macrophages
Danne, C., Ryzhakov, G., Martínez-López, M., Ilott, N. E., Franchini, F., Cuskin, F., Lowe, E. C., Bullers, S. J., Arthur, J. S. C. & Powrie, F., 13 Dec 2017, In: Cell Host & Microbe. 22, 6, p. 733-745.e5 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile33 Citations (Scopus)254 Downloads (Pure) -
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
Sung, Y. J., Winkler, T. W., De Las Fuentes, L., Bentley, A. R., Brown, M. R., Kraja, A. T., Schwander, K., Ntalla, I., Guo, X., Franceschini, N., Lu, Y., Cheng, C., Sim, X., Vojinovic, D., Marten, J., Musani, S. K., Li, C., Feitosa, M. F., Kilpeläinen, T. O., Richard, M. A. & 277 others, , 1 Mar 2018, In: American Journal of Human Genetics. 102, 3, p. 375-400 26 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Citations (Scopus)136 Downloads (Pure) -
Albrecht Nagel on vision with two eyes
Wade, N. J., 19 Aug 2020, In: Strabismus. 28, 3, p. 115-118 4 p.Research output: Contribution to journal › Article › peer-review
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Alchemical Free Energy Calculations and Isothermal Titration Calorimetry Measurements of Aminoadamantanes Bound to the Closed State of Influenza A/M2TM
Ioannidis, H., Drakopoulos, A., Tzitzoglaki, C., Homeyer, N., Kolarov, F., Gkeka, P., Freudenberger, K., Liolios, C., Gauglitz, G., Cournia, Z., Gohlke, H. & Kolocouris, A., 23 May 2016, In: Journal of Chemical Information and Modeling. 56, 5, p. 862-876 15 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
Alcohol and disadvantaged men: a feasibility trial of an intervention delivered by mobile phone
Crombie, I. K., Irvine, L., Falconer, D. W., Williams, B., Ricketts, I. W., Jones, C., Humphris, G. M., Norrie, J., Slane, P. & Rice, P., 5 Jul 2017, In: Drug and Alcohol Review. 36, 4, p. 468-476 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)178 Downloads (Pure) -
Alcohol and learning disability: personal problem or cultural exclusion?
Simpson, M., 2012, In: Journal of Intellectual Disabilities. 16, 3, p. 183-192 10 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
Alcohol and mouth cancer
Ogden, G., 9 Nov 2018, In: British Dental Journal. 225, 9, p. 880-883 4 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)413 Downloads (Pure) -
Alcohol and the dental team: Relevance, risk, role and responsibility
Shepherd, S. & Ogden, G., Jun 2017, In: Dental Update. 44, 6, p. 495-501 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)180 Downloads (Pure) -
Alcohol exposure induces chick craniofacial bone defects by negatively affecting cranial neural crest development
Zhang, P., Wang, G., Lin, Z., Wu, Y., Zhang, J., Liu, M., Lee, K. K. H., Chuai, M. & Yang, X., 5 Nov 2017, In: Toxicology Letters. 281, p. 53-64 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)371 Downloads (Pure) -
ALDH2 mediates 5-nitrofuran activity in multiple species
Zhou, L., Ishizaki, H., Spitzer, M., Taylor, K. L., Temperley, N. D., Johnson, S. L., Brear, P., Gautier, P., Zeng, Z., Mitchell, A., Narayan, V., McNeil, E. M., Melton, D. W., Smith, T. K., Tyers, M., Westwood, N. J. & Patton, E. E., 27 Jul 2012, In: Chemistry & Biology. 19, 7, p. 883-892 10 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer
MacLeod, A. K., Acosta-Jimenez, L., Coates, P. J., McMahon, M., Carey, F. A., Honda, T., Henderson, C. J. & Wolf, C. R., 6 Dec 2016, In: British Journal of Cancer. 115, 12, p. 1530-1539 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)245 Downloads (Pure) -
A Leptin Fragment Mirrors the Cognitive Enhancing and Neuroprotective Actions of Leptin
Malekizadeh, Y., Holiday, A., Redfearn, D., Ainge, J. A., Doherty, G. & Harvey, J., 6 Sep 2016, In: Cerebral Cortex. 27, 10, p. 4769-4782 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)175 Downloads (Pure) -
A leucine aminopeptidase is involved in kinetoplast DNA segregation in Trypanosoma brucei
Peña-Diaz, P., Vancová, M., Resl, C., Field, M. C. & Lukeš, J., 7 Apr 2017, In: PLoS Pathogens. 13, 4, p. 1-23 23 p., e1006310.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)239 Downloads (Pure) -
Alfvénic wave heating of the upper chromosphere in flares
Reep, J. W. & Russell, A. J. B., 9 Feb 2016, In: Astrophysical Journal Letters. 818, 1, p. 1-5 5 p., L20.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Citations (Scopus)164 Downloads (Pure) -
Algae as nutritional and functional food sources: revisiting our understanding
Wells, M. L., Potin, P., Craigie, J. S., Raven, J. A., Merchant, S. S., Helliwell, K. E., Smith, A. G., Camire, M. E. & Brawley, S. H., Apr 2017, In: Journal of Applied Phycology. 29, 2, p. 949-982 34 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile396 Citations (Scopus)323 Downloads (Pure) -
Algal biogeography: Metagenomics shows distribution of a picoplanktonic pelagophyte
Raven, J. A., 2012, In: Current Biology. 22, 17Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
Algorithms and Medial Efficacy
Lushetich, N., 13 Jan 2020, In: The Philosophical Salon.Research output: Contribution to journal › Article
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Alignment-free design of highly discriminatory diagnostic primer sets for Escherichia coli O104: H4 outbreak strains
Pritchard, L., Holden, N. J., Bielaszewska, M., Karch, H. & Toth, I. K., 5 Apr 2012, In: PLoS ONE. 7, 4, 8 p., e34498.Research output: Contribution to journal › Article › peer-review
24 Citations (Scopus) -
A likely close-in low-mass stellar companion to the transitional disk star HD 142527
Biller, B., Lacour, S., Juhasz, A., Benisty, M., Chauvin, G., Olofsson, J., Pott, J-U., Mueller, A., Sicilia-Aguilar, A., Bonnefoy, M., Tuthill, P., Thebault, P., Henning, T. & Crida, A., 26 Jun 2012, In: Astrophysical Journal Letters. 753, 2, 5 p., L38.Research output: Contribution to journal › Article › peer-review
110 Citations (Scopus) -
A limited memory steepest descent method
Fletcher, R., Oct 2012, In: Mathematical Programming. 135, 1-2, p. 413-436 24 p.Research output: Contribution to journal › Article › peer-review
40 Citations (Scopus) -
Allelic diversity of S-RNase alleles in diploid potato species
Dzidzienyo, D. K., Bryan, G. J., Wilde, G. & Robbins, T. P., Oct 2016, In: Theoretical and Applied Genetics. 129, 10, p. 1985-2001 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)195 Downloads (Pure) -
Allergic Rhinitis and its Impact on Asthma (ARIA): Achievements in 10 years and future needs
Bousquet, J., Schünemann, H. J., Samolinski, B., Demoly, P., Baena-Cagnani, C. E., Bachert, C., Bonini, S., Boulet, L. P., Bousquet, P. J., Brozek, J. L., Canonica, G. W., Casale, T. B., Cruz, A. A., Fokkens, W. J., Fonseca, J. A., Van Wijk, R. G., Grouse, L., Haahtela, T., Khaltaev, N., Kuna, P. & 213 others, , 2012, In: Journal of Allergy and Clinical Immunology. 130, 5, p. 1049-1062 14 p.Research output: Contribution to journal › Article › peer-review
377 Citations (Scopus) -
Allopurinol: novel indications in cardiovascular disease
Struthers, A. & Shearer, F., 2012, In: Heart. 98, 21, p. 1543-1545 3 p.Research output: Contribution to journal › Article › peer-review
25 Citations (Scopus) -
Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation
Orriss, I. R., Arnett, T. R., George, J. & Witham, M. D., 15 Mar 2016, In: Experimental Cell Research. 342, 2, p. 166-174 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)183 Downloads (Pure) -
Allopurinol in Patients with Pulmonary Hypertension Associated with Chronic Lung Disease
Liu Shiu Cheong, P. S. K., Lipworth, B. J., Weir-McCall, J. R., Houston, J. G. & Struthers, A. D., 25 Aug 2020, In: International Journal of Chronic Obstructive Pulmonary Disease. 2020, 15, p. 2015-2024 10 p.Research output: Contribution to journal › Article › peer-review
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Allosteric competitive inhibitors of the glucose-1-phosphate Thymidylyltransferase (RmlA) from seudomonas aeruginosa
Alphey, M. S., Pirrie, L., Torrie, L. S., Boulkeroua, W. A., Gardiner, M., Sarkar, A., Maringer, M., Oehlmann, W., Brenk, R., Scherman, M. S., McNeil, M., Rejzek, M., Field, R. A., Singh, M., Gray, D., Westwood, N. J. & Naismith, J. H., 2012, In: ACS Chemical Biology.Research output: Contribution to journal › Article › peer-review
21 Citations (Scopus) -
Allosteric mechanism for site-specific ubiquitination of FANCD2
Chaugule, V. K., Arkinson, C., Rennie, M. L., Kämäräinen, O., Toth, R. & Walden, H., Mar 2020, In: Nature Chemical Biology. 16, p. 291-301 11 p.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
Allosteric targeting of the Fanconi anemia ubiquitin-conjugating enzyme Ube2T by fragment screening
Morreale, F., Bortoluzzi, A., Chaugule, V., Arkinson, C., Walden, H. & Ciulli, A., 11 May 2017, In: Journal of Medicinal Chemistry. 60, 9, p. 4093-4098 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)213 Downloads (Pure) -
Alloyed quaternary/binary core/shell quantum dot-graphene oxide nanocomposite: Preparation, characterization and application as a fluorescence “switch ON” probe for environmental pollutants
Adegoke, O., Montaseri, H., Nsibande, S. A. & Forbes, P. B. C., 5 Oct 2017, In: Journal of Alloys and Compounds. 720, p. 70-78 9 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
All patients with diabetes should have annual UACR tests. Why is that so hard?
Willison, A., Tully, V. & Davey, P., 20 Sep 2016, In: BMJ Quality Improvement Reports. 5, 1, 6 p.Research output: Contribution to journal › Article › peer-review
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All roads lead to susceptibility: the many modes-of-action of fungal and oomycete intracellular effectors
He, Q., McLellan, H., Boevink, P. C. & Birch, P. R. J., 13 Jul 2020, In: Plant Communications. 1, 4, 12 p., 100050.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)18 Downloads (Pure) -
ALMA and VLA Observations of EX Lupi in its Quiescent State
White, J. A., Kóspál, Á., Hughes, A. G., Ábrahám, P., Akimkin, V., Banzatti, A., Chen, L., Miera, F. C-S. D., Dutrey, A., Flock, M., Guilloteau, S., Hales, A. S., Henning, T., Kadam, K., Semenov, D., Sicilia-Aguilar, A., Teague, R. & Vorobyov, E. I., 20 Nov 2020, In: Astrophysical Journal. 904, 1, 15 p., 37.Research output: Contribution to journal › Article › peer-review
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AlmostSignificant: simplifying quality control of high-throughput sequencing data
Ward, J., Cole, C., Febrer, M. & Barton, G. J., 15 Dec 2016, In: Bioinformatics. 32, 24, p. 3850-3851 2 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)117 Downloads (Pure) -
A longitudinal qualitative exploration of healthcare and informal support needs among survivors of critical illness: the RELINQUISH protocol
Ramsay, P., Huby, G., Rattray, J., Salisbury, L. G., Walsh, T. S. & Kean, S., 16 Jul 2012, In: BMJ Open. 2, 4, p. 1-7 7 p., e001507.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)52 Downloads (Pure) -
A longitudinal study of multi-word constructions in L2 academic writing: The effects of frequency and dispersion
Candarli, D., 6 Dec 2020, In: Reading and Writing. 0, p. 1-33 33 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk
Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 242 others, , Jul 2017, In: Diabetes. 66, 7, p. 2019-2032 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)47 Downloads (Pure) -
Altered metabolic parameters in association with antipsychotic medication use in diabetes: A population based case-control study
Wake, D. J., Broughton, P., Perera, S. M., MacIntyre, D. J. & Leese, G. P., Apr 2016, In: Psychoneuroendocrinology. 66, p. 214-220 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)181 Downloads (Pure) -
Altered signaling associated with chronic arsenic exposure in human skin keratinocytes
Mir, S. A., Renuse, S., Sathe, G., Khan, A. A., Patil, A. H., Nanjappa, V., Bhat, F. A., Prasad, T. S. K., Giri, A. K., Chatterjee, A. & Gowda, H., 18 Dec 2017, In: Proteomics - Clinical Applications. 11, 11-12, 5 p., 1700004.Research output: Contribution to journal › Article › peer-review
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Alternate thermoregulation and functional binding of Escherichia coli type 1 fimbriae in environmental and animal isolates
Marshall, J., Rossez, Y., Mainda, G., Gally, D. L., Daniell, T. J. & Holden, N. J., Nov 2016, In: FEMS Microbiology Letters. 363, 22, p. 1-8 8 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Alternative caries management options for primary molars: 2.5-yr outcomes of a randomised clinical trial
Santamaria, R. M., Innes, N., Machiulskiene, V., Schmoeckel, J., Alkilzy, M. & Splieth, C. H., 20 Dec 2017, In: Caries Research. 51, 6, p. 605-614Research output: Contribution to journal › Article › peer-review
Open AccessFile45 Citations (Scopus)345 Downloads (Pure) -
Alternative splicing and nonsense-mediated decay modulate expression of important regulatory genes in Arabidopsis
Kalyna, M., Simpson, C. G., Syed, N. H., Lewandowska, D., Marquez, Y., Kusenda, B., Marshall, J., Fuller, J., Cardle, L., McNicol, J., Dinh, H. Q., Barta, A. & Brown, J. W. S., Mar 2012, In: Nucleic Acids Research. 40, 6, p. 2454-2469 16 p.Research output: Contribution to journal › Article › peer-review
255 Citations (Scopus) -
Alternative splicing in plants-coming of age
Hasan-Syed, N., Kalyna, M., Marquez, Y., Barta, A. & Brown, J. W. S., 2012, In: Trends in Plant Science. 17, 10, p. 616-623 8 p.Research output: Contribution to journal › Article › peer-review
257 Citations (Scopus) -
Alternative splicing mediates responses of the Arabidopsis circadian clock to temperature changes
James, A. B., Syed, N. H., Bordage, S., Marshall, J., Nimmo, G. A., Jenkins, G. I., Herzyk, P., Brown, J. W. S. & Nimmo, H. G., 2012, In: Plant Cell. 24, 3, p. 961-981 21 p.Research output: Contribution to journal › Article › peer-review
207 Citations (Scopus) -
Alternative splicing of barley clock genes in response to low temperature: evidence for alternative splicing conservation
Calixto, C. P. G., Simpson, C. G., Waugh, R. & Brown, J. W. S., 13 Dec 2016, In: PLoS ONE. 11, 12, p. 1-24 24 p., e0168028.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)174 Downloads (Pure) -
Alternatives to imprisonment in Scotland: policy, strategy and practice
Freeman, R. & Lloyd, G., 19 Dec 2016, In: Criminology, Victimology and Security Review. 10, 3, p. 60-72Research output: Contribution to journal › Article › peer-review
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Alzheimer's disease risk factor complement receptor 1 is associated with depression
Hamilton, G., Evans, K. L., MacIntyre, D. J., Deary, I. J., Dominiczak, A., Smith, B. H., Morris, A. D., Porteous, D. J. & Thomson, P. A., 2012, In: Neuroscience Letters. 510, 1, p. 6-9 4 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus)