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Article
A molecular explanation for the recessive nature of parkin-linked Parkinson's disease
Spratt, D. E., Julio Martinez-Torres, R., Noh, Y. J., Mercier, P., Manczyk, N., Barber, K. R., Aguirre, J. D., Burchell, L., Purkiss, A., Walden, H. & Shaw, G. S., 1 Jan 2013, In: Nature Communications. 4, 12 p., 1983.Research output: Contribution to journal › Article › peer-review
87 Citations (Scopus) -
A More Scientific Approach to Applied Economics: Reconstructing Statistical, Analytical Significance, and Correlation Analysis
Altman, M., 28 Feb 2019, In: SSRN Working Paper Series. 23 p.Research output: Contribution to journal › Article
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A Morphological identification cell cytotoxicity assay using cytoplasm-localized fluorescent probe (CLFP) to distinguish living and dead cells
Lai, F., Shen, Z., Wen, H., Chen, J., Zhang, X., Lin, P., Yin, D., Cui, H. & Chen, X., 8 Jan 2017, In: Biochemical and Biophysical Research Communications. 482, 2, p. 257-263 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)400 Downloads (Pure) -
A mouse model for functional dissection of TAB1 O-GlcNAcylation
Authier, F., Muha, V. & van Aalten, D. M. F., 27 Aug 2019, In: Wellcome Open Research. 4, 16 p., 128.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
A moving interface finite element formulation for layered structures
Funari, M. F., Greco, F. & Lonetti, P., 1 Jul 2016, In: Composites Part B: Engineering. 96, p. 325-337 13 p.Research output: Contribution to journal › Article › peer-review
33 Citations (Scopus) -
A moving interface finite element formulation to predict dynamic edge debonding in FRP-strengthened concrete beams in service conditions
Funari, M. F., Spadea, S., Fabbrocino, F. & Luciano, R., Jun 2020, In: Fibers. 8, 6, p. 1-9 9 p., 42.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
AMP-activated protein kinase: a cellular energy sensor that comes in twelve flavours
Ross, F. A., MacKintosh, C. & Hardie, D. G., 24 Mar 2016, In: FEBS Journal. 283, 16, p. 2987-3001 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile135 Citations (Scopus)112 Downloads (Pure) -
AMP-activated protein kinase (AMPK)α2 plays a role in determining the cellular fate of glucose in insulin-resistant mouse skeletal muscle
Lee-Young, R. S., Bonner, J. S., Mayes, W. H., Iwueke, I., Barrick, B. A., Hasenour, C. M., Kang, L. & Wasserman, D. H., Mar 2013, In: Diabetologia. 56, 3, p. 608-617 10 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner
Vlachaki Walker, J. M., Robb, J. L., Cruz, A. M., Malhi, A., Weightman Potter, P. G., Ashford, M. L. J., McCrimmon, R. J., Ellacott, K. L. J. & Beall, C., 21 Apr 2017, In: Diabetes, Obesity & Metabolism. 19, 7, p. 997-1005 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)290 Downloads (Pure) -
AMP-activated protein kinase inhibits Kv1.5 channel currents of pulmonary arterial myocytes in response to hypoxia and inhibition of mitochondrial oxidative phosphorylation
Moral-Sanz, J., Mahmoud, A. D., Ross, F. A., Eldstrom, J., Fedida, D., Hardie, D. G. & Evans, A. M., 1 Sep 2016, In: Journal of Physiology. 594, 17, p. 4901-4915 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)157 Downloads (Pure) -
Amphiphilic oxygenated amorphous carbon-graphite buckypapers with gas sensitivity to polar and non-polar VOCs
Homaeigohar, S., Sep 2019, In: Nanomaterials. 9, 9, p. 1-14 14 p., 1343.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)16 Downloads (Pure) -
AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation
Gowans, G. J., Hawley, S. A., Ross, F. A. & Hardie, D. G., 1 Oct 2013, In: Cell Metabolism. 18, 4, p. 556-566 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile272 Citations (Scopus)159 Downloads (Pure) -
AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?
Dandapani, M. & Hardie, D. G., Apr 2013, In: Biochemical Society Transactions. 41, 2, p. 687-693 7 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
AMPK: a target for drugs and natural products with effects on both diabetes and cancer
Hardie, D. G., Jul 2013, In: Diabetes. 62, 7, p. 2164-2172 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile263 Citations (Scopus)133 Downloads (Pure) -
AMPK: regulating energy balance at the cellular and whole body levels
Hardie, D. G. & Ashford, M. L. J., Mar 2014, In: Physiology. 29, 2, p. 99-107 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile161 Citations (Scopus)160 Downloads (Pure) -
AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1-Parkin independent manner
Seabright, A. P., Fine, N. H. F., Barlow, J. P., Lord, S. O., Musa, I., Gray, A., Bryant, J. A., Banzhaf, M., Lavery, G. G., Hardie, D. G., Hodson, D. J., Philp, A. & Lai, Y-C., 4 May 2020, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 5, p. 6284-6301 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)77 Downloads (Pure) -
AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B
Johanns, M., Lai, Y. C., Hsu, M. F., Jacobs, R., Vertommen, D., Van Sande, J., Dumont, J. E., Woods, A., Carling, D., Hue, L., Viollet, B., Foretz, M. & Rider, M. H., 8 Mar 2016, In: Nature Communications. 7, 10856.Research output: Contribution to journal › Article › peer-review
Open Access54 Citations (Scopus) -
AMPK Causes Cell Cycle Arrest in LKB1-deficient Cells via Activation of CAMKK2
Fogarty, S., Ross, F. A., Vara Ciruelos, D., Gray, A., Gowans, G. J. & Hardie, D. G., 1 Aug 2016, In: Molecular Cancer Research. 14, 8, p. 683-695 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Citations (Scopus)310 Downloads (Pure) -
AMPK dilates resistance arteries via activation of SERCA and BKCa channels in smooth muscle
Schneider, H., Schubert, K. M., Blodow, S., Kreutz, C-P., Erdogmus, S., Wiedenmann, M., Qiu, J., Fey, T., Ruth, P., Lubomirov, L. T., Pfitzer, G., Mederos y Schnitzler, M., Hardie, D. G., Gudermann, T. & Pohl, U., Jul 2015, In: Hypertension. 66, 1, p. 108-116 9 p.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus) -
AMPK modulates glucose-sensing in insulin-secreting cells by altered phosphotransfer to KATP channels
Beall, C., Watterson, K. R., McCrimmon, R. J. & Ashford, M. L. J., Jun 2013, In: Journal of Bioenergetics and Biomembranes. 45, 3, p. 229-241 13 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
AMPK-sensing energy while talking to other signaling pathways
Hardie, D. G., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 939-952 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile311 Citations (Scopus)151 Downloads (Pure) -
AMPKα1: a glucose sensor that controls CD8 T-cell memory
Rolf, J., Zarrouk, M., Finlay, D. K., Foretz, M., Viollet, B. & Cantrell, D. A., Apr 2013, In: European Journal of Immunology. 43, 4, p. 889-896 8 p.Research output: Contribution to journal › Article › peer-review
133 Citations (Scopus) -
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
LifeLines Cohort Study, Sung, Y. J., de Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D. & 40 others, , 1 Aug 2019, In: Human Molecular Genetics. 28, 15, p. 2615-2633 19 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)59 Downloads (Pure) -
A Multicenter, Randomized, Placebo-Controlled Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients With Rheumatoid Arthritis: A multicenter, randomized, placebo controlled trial
Kitas, G. D., Nightingale, P., Armitage, J., Sattar, N., Belch, J. J. F. & Symmons, D. P. M., Sep 2019, In: Arthritis and Rheumatology. 71, 9, p. 1437-1449 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (Scopus)40 Downloads (Pure) -
A multi-centre, parallel group superiority trial of silk therapeutic clothing compared to standard care for the management of eczema in children (CLOTHES Trial): study protocol for a randomised controlled trial
Harrison, E. F., Haines, R. H., Cowdell, F., Sach, T. H., Dean, T., Pollock, I., Burrows, N. P., Buckley, H., Batchelor, J., Williams, H. C., Lawton, S., Brown, S. J., Bradshaw, L. E., Ahmed, A., Montgomery, A. A., Mitchell, E. J. & Thomas, K. S., 2 Sep 2015, In: Trials. 16, 12 p., 390.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)171 Downloads (Pure) -
A multi-centre, prospective epidemiological surveillance study considering ophthalmic complications of functional endoscopic sinus surgery
Burgess, S., Foulds, J., White, P., Foot, B. & Macewen, C., Mar 2020, In: Journal of Laryngology and Otology. 134, 3, p. 228-232 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)40 Downloads (Pure) -
A multicentre parallel-group randomised trial assessing multiparametric MRI characterisation and image-guided biopsy of prostate in men suspected of having prostate cancer: MULTIPROS study protocol
Szewczyk-Bieda, M., Wei, C., Coll, K., Gandy, S., Donnan, P., Ragupathy, S. K. A., Singh, P., Wilson, J. & Nabi, G., 21 Nov 2019, In: Trials. 20, p. 1-8 8 p., 638.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)71 Downloads (Pure) -
A Multi-disciplinary Approach to the Archaeological Investigation of a Bedrock-Dominated Shallow-Marine Landscape: An example from the Bay of Firth, Orkney, UK
Bates, M. R., Nayling, N., Bates, R., Dawson, S., Huws, D. & Wickham-Jones, C., Mar 2013, In: International Journal of Nautical Archaeology. 42, 1, p. 24-43 20 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
A multidisciplinary intervention to reduce antibiotic duration in lower respiratory tract infections
Murray, C., Shaw, A., Lloyd, M., Smith, R. P., Fardon, T. C., Schembri, S. & Chalmers, J. D., Feb 2014, In: Journal of Antimicrobial Chemotherapy. 69, 2, p. 515-518 4 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13
Leslie, E. J., Carlson, J. C., Shaffer, J. R., Feingold, E., Wehby, G., Laurie, C. A., Jain, D., Laurie, C. C., Doheny, K. F., McHenry, T., Resick, J., Sanchez, C., Jacobs, J., Emanuele, B., Vieira, A. R., Neiswanger, K., Lidral, A. C., Valencia-Ramirez, L. C., Lopez-Palacio, A. M., Valencia, D. R. & 35 others, , 1 Jul 2016, In: Human Molecular Genetics. 25, 13, p. 2862-2872 11 p.Research output: Contribution to journal › Article › peer-review
86 Citations (Scopus) -
A multifaceted intervention to improve sepsis management in general hospital wards with evaluation using segmented regression of interrupted time series
Marwick, C. A., Guthrie, B., Pringle, J. E. C., Evans, J. M. M., Nathwani, D., Donnan, P. T. & Davey, P. G., Dec 2014, In: BMJ Quality & Safety. 23, 12, 8 p., e2.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
A multimodal approach to cardiovascular risk stratification in patients with type 2 diabetes incorporating retinal, genomic and clinical features
Fetit, A., Doney, A., Hogg, S., Wang, R., MacGillivray, T., Wardlaw, J. M., Doubal, F. N., McKay, G. J., McKenna, S. & Trucco, E., 5 Mar 2019, In: Scientific Reports. 9, 10 p., 3591.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)133 Downloads (Pure) -
A multiorganism pipeline for antiseizure drug discovery: Identification of chlorothymol as a novel γ-aminobutyric acidergic anticonvulsant
Jones, A., Barker-Haliski, M., Ilie, A. S., Herd, M. B., Baxendale, S., Holdsworth, C. J., Ashton, J. P., Placzek, M., Jayasekera, B. A. P., Cowie, C. J. A., Lambert, J. J., Trevelyan, A. J., White, H. S., Marson, A. G., Cunliffe, V. T., Sills, G. J. & Morgan, A., 14 Aug 2020, In: Epilepsia. 13 p.Research output: Contribution to journal › Article › peer-review
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A multiscale mathematical model of tumour invasive growth
Peng, L., Trucu, D., Lin, P., Thompson, A. & Chaplain, M. A. J., Mar 2017, In: Bulletin of Mathematical Biology. 79, 3, p. 389-429 41 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)172 Downloads (Pure) -
A multiscale moving boundary model arising in cancer invasion
Trucu, D., Lin, P., Chaplain, M. A. J. & Wang, Y., 2013, In: Multiscale Modeling and Simulation: A SIAM Interdisciplinary Journal. 11, 1, p. 309-335 27 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
A mutant O-GlcNAcase as a probe to reveal global dynamics of protein O-GlcNAcylation during Drosophila embryonic development
Mariappa, D., Selvan, N., Borodkin, V. S., Alonso, J., Ferenbach, A. T., Shepherd, C., Navratilova, I. H. & Van Aalten, D. M. F., Sep 2015, In: Biochemical Journal. 470, 2, p. 255-262 8 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
A mutant O-GlcNAcase enriches Drosophila developmental regulators
Selvan, N., Williamson, R., Mariappa, D., Campbell, D. G., Gourlay, R., Ferenbach, A. T., Aristotelous, T., Hopkins-Navratilova, I., Trost, M. & van Aalten, D. M. F., Aug 2017, In: Nature Chemical Biology. 13, 8, p. 882-887 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)199 Downloads (Pure) -
A mutual health service in Scotland: Do we understand fully the leadership implications?
Howieson, B. & Fenwick, C., Jul 2014, In: Leadership in Health Services. 27, 3, p. 193-203 11 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease
Pickett, E. K., Herrmann, A. G., McQueen, J., Abt, K., Dando, O., Tulloch, J., Jain, P., Dunnett, S., Sohrabi, S., Fjeldstad, M. P., Calkin, W., Murison, L., Jackson, R. J., Tzioras, M., Stevenson, A., d'Orange, M., Hooley, M., Davies, C., Colom-Cadena, M., Anton-Fernandez, A. & 10 others, , 10 Dec 2019, In: Cell Reports. 29, 11, p. 3592-3604.e5Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)70 Downloads (Pure) -
Amyloid β fibril disruption by oleuropein aglycone: long-time molecular dynamics simulation to gain insight into the mechanism of action of this polyphenol from extra virgin olive oil
Brogi, S., Sirous, H., Calderone, V. & Chemi, G., 23 Sep 2020, In: Food & Function. 11, 9, p. 8122-8132 11 p.Research output: Contribution to journal › Article › peer-review
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Anabolic resistance does not explain sarcopenia in patients with type 2 diabetes mellitus, compared with healthy controls, despite reduced mTOR pathway activity
Cuthbertson, D. J., Babraj, J., Leese, G. & Siervo, M., Dec 2017, In: Clinical Nutrition. 36, 6, p. 1716-1719 4 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
An activatable cancer-targeted hydrogen peroxide probe for photoacoustic and fluorescence imaging
Weber, J., Bollepalli, L., Belenguer, A. M., Antonio, M. D., De Mitri, N., Joseph, J., Balasubramanian, S., Hunter, C. A. & Bohndiek, S. E., 15 Oct 2019, In: Cancer Research. 79, 20, p. 5407-5417 11 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
An adaptive IEEE 802.15.4 MAC layer transmission scheme for applications with heterogeneous traffic
Zhou, Y., He, J., Chen, K., Tang, Z. & Li, Y., Dec 2013, In: Information: An Interdisciplinary Journal in English, Japanese and Chinese . 16, 12 A, p. 8451-8456 6 p.Research output: Contribution to journal › Article › peer-review
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Anaesthesia for laryngo-tracheal surgery, including tubeless field techniques
Pearson, K. L. & McGuire, B. E., 1 Jul 2017, In: BJA Education. 17, 7, p. 242-248 7 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
An Affinity-directed PROtein Missile (AdPROM) system for targeted proteolysis
Fulcher, L., Macartney, T., Bozatzi, P., Hornberger, A., Rojas-Fernandez, A. & Sapkota, G., 26 Oct 2016, In: Open Biology. 6, 10, p. 1-9 9 p., 160255.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Citations (Scopus)170 Downloads (Pure) -
An African Legal Philosophy of Disability Justice: Between Discovery and Recognition
Onazi, O., 30 Jun 2016, In: ISRF Bulletin. Discovery & Recognition, X, p. 33-38 6 p.Research output: Contribution to journal › Article
Open AccessFile760 Downloads (Pure) -
An algorithm recommendation for the pharmacological management of allergic rhinitis in the UK: a consensus statement from an expert panel
Lipworth, B., Newton, J., Ram, B., Small, I. & Schwarze, J., 23 Jan 2017, In: NPJ Primary Care Respiratory Medicine. 27, p. 1-8 8 p., 3.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)169 Downloads (Pure) -
Análisis de la formación y el ámbito de práctica de los médicos de atención primaria en Inglaterra, Alemania y España
Glonti, K., Struckmann, V., Alconada, A., Pettigrew, L. M., Hernandez-Santiago, V., Minue, S., Risso-Gill, I., McKee, M. & Legido-Quigley, H., Mar 2019, In: Gaceta Sanitaria. 33, 2, p. 148-155 8 p.Research output: Contribution to journal › Article › peer-review
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An alternate route to phosphorylating DegU of Bacillus subtilis using acetyl phosphate
Cairns, L. S., Martyn, J. E., Bromley, K. & Stanley-Wall, N. R., 31 Mar 2015, In: BMC Microbiology. 15, 12 p., 78.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
An Alternative Genealogy for Global Capitalism: The Rhine Becomes an Inland Sea 1792-1815
Livesey, J., 1 Nov 2019, In: Critical Historical Studies. 6, 2, p. 223-245 23 p.Research output: Contribution to journal › Article › peer-review
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