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A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1
Liu, Y., Freeman, A. D. J., Déclais, A-C. & Lilley, D. M. J., 16 Nov 2018, In: Nucleic Acids Research. 46, 20, p. 11089-11098 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)110 Downloads (Pure) -
A Morphological identification cell cytotoxicity assay using cytoplasm-localized fluorescent probe (CLFP) to distinguish living and dead cells
Lai, F., Shen, Z., Wen, H., Chen, J., Zhang, X., Lin, P., Yin, D., Cui, H. & Chen, X., 8 Jan 2017, In: Biochemical and Biophysical Research Communications. 482, 2, p. 257-263 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)400 Downloads (Pure) -
AMP-activated protein kinase (AMPK)α2 plays a role in determining the cellular fate of glucose in insulin-resistant mouse skeletal muscle
Lee-Young, R. S., Bonner, J. S., Mayes, W. H., Iwueke, I., Barrick, B. A., Hasenour, C. M., Kang, L. & Wasserman, D. H., Mar 2013, In: Diabetologia. 56, 3, p. 608-617 10 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner
Vlachaki Walker, J. M., Robb, J. L., Cruz, A. M., Malhi, A., Weightman Potter, P. G., Ashford, M. L. J., McCrimmon, R. J., Ellacott, K. L. J. & Beall, C., 21 Apr 2017, In: Diabetes, Obesity & Metabolism. 19, 7, p. 997-1005 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)290 Downloads (Pure) -
AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation
Gowans, G. J., Hawley, S. A., Ross, F. A. & Hardie, D. G., 1 Oct 2013, In: Cell Metabolism. 18, 4, p. 556-566 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile272 Citations (Scopus)159 Downloads (Pure) -
AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?
Dandapani, M. & Hardie, D. G., Apr 2013, In: Biochemical Society Transactions. 41, 2, p. 687-693 7 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
AMPK: a target for drugs and natural products with effects on both diabetes and cancer
Hardie, D. G., Jul 2013, In: Diabetes. 62, 7, p. 2164-2172 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile263 Citations (Scopus)133 Downloads (Pure) -
AMPK: regulating energy balance at the cellular and whole body levels
Hardie, D. G. & Ashford, M. L. J., Mar 2014, In: Physiology. 29, 2, p. 99-107 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile161 Citations (Scopus)160 Downloads (Pure) -
AMPK dilates resistance arteries via activation of SERCA and BKCa channels in smooth muscle
Schneider, H., Schubert, K. M., Blodow, S., Kreutz, C-P., Erdogmus, S., Wiedenmann, M., Qiu, J., Fey, T., Ruth, P., Lubomirov, L. T., Pfitzer, G., Mederos y Schnitzler, M., Hardie, D. G., Gudermann, T. & Pohl, U., Jul 2015, In: Hypertension. 66, 1, p. 108-116 9 p.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus) -
AMPK modulates glucose-sensing in insulin-secreting cells by altered phosphotransfer to KATP channels
Beall, C., Watterson, K. R., McCrimmon, R. J. & Ashford, M. L. J., Jun 2013, In: Journal of Bioenergetics and Biomembranes. 45, 3, p. 229-241 13 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
AMPK-sensing energy while talking to other signaling pathways
Hardie, D. G., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 939-952 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile312 Citations (Scopus)152 Downloads (Pure) -
AMPKα1: a glucose sensor that controls CD8 T-cell memory
Rolf, J., Zarrouk, M., Finlay, D. K., Foretz, M., Viollet, B. & Cantrell, D. A., Apr 2013, In: European Journal of Immunology. 43, 4, p. 889-896 8 p.Research output: Contribution to journal › Article › peer-review
136 Citations (Scopus) -
Amputation-free survival in 17,353 people at high risk for foot ulceration in diabetes: a national observational study
Scottish Diabetes Research Network Epidemiology Group, Vadiveloo, T., Jeffcoate, W., Donnan, P. T., Colhoun, H. C., McGurnaghan, S., Wild, S., McCrimmon, R. & Leese, G. P., Dec 2018, In: Diabetologia. 61, 12, p. 2590-2597 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)188 Downloads (Pure) -
A Multicellular Model of Intestinal Crypt Buckling and Fission
Almet, A. A., Hughes, B. D., Landman, K. A., Näthke, I. S. & Osborne, J. M., Feb 2018, In: Bulletin of Mathematical Biology. 80, 2, p. 335-359 25 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)228 Downloads (Pure) -
A multi-centre, parallel group superiority trial of silk therapeutic clothing compared to standard care for the management of eczema in children (CLOTHES Trial): study protocol for a randomised controlled trial
Harrison, E. F., Haines, R. H., Cowdell, F., Sach, T. H., Dean, T., Pollock, I., Burrows, N. P., Buckley, H., Batchelor, J., Williams, H. C., Lawton, S., Brown, S. J., Bradshaw, L. E., Ahmed, A., Montgomery, A. A., Mitchell, E. J. & Thomas, K. S., 2 Sep 2015, In: Trials. 16, 12 p., 390.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)172 Downloads (Pure) -
A Multi-disciplinary Approach to the Archaeological Investigation of a Bedrock-Dominated Shallow-Marine Landscape: An example from the Bay of Firth, Orkney, UK
Bates, M. R., Nayling, N., Bates, R., Dawson, S., Huws, D. & Wickham-Jones, C., Mar 2013, In: International Journal of Nautical Archaeology. 42, 1, p. 24-43 20 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
A multidisciplinary intervention to reduce antibiotic duration in lower respiratory tract infections
Murray, C., Shaw, A., Lloyd, M., Smith, R. P., Fardon, T. C., Schembri, S. & Chalmers, J. D., Feb 2014, In: Journal of Antimicrobial Chemotherapy. 69, 2, p. 515-518 4 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
A multifaceted approach to identify non-specific enzyme inhibition: Application to Mycobacterium tuberculosis shikimate kinase
Alturki, M. S., Fuanta, N. R., Jarrard, M. A., Hobrath, J. V., Goodwin, D. C., Rants'o, T. A. & Calderón, A. I., 15 Feb 2018, In: Bioorganic and Medicinal Chemistry Letters. 28, 4, p. 802-808 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)159 Downloads (Pure) -
A multifaceted intervention to improve sepsis management in general hospital wards with evaluation using segmented regression of interrupted time series
Marwick, C. A., Guthrie, B., Pringle, J. E. C., Evans, J. M. M., Nathwani, D., Donnan, P. T. & Davey, P. G., Dec 2014, In: BMJ Quality & Safety. 23, 12, 8 p., e2.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
A multiscale mathematical model of tumour invasive growth
Peng, L., Trucu, D., Lin, P., Thompson, A. & Chaplain, M. A. J., Mar 2017, In: Bulletin of Mathematical Biology. 79, 3, p. 389-429 41 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)172 Downloads (Pure) -
A multiscale moving boundary model arising in cancer invasion
Trucu, D., Lin, P., Chaplain, M. A. J. & Wang, Y., 2013, In: Multiscale Modeling and Simulation: A SIAM Interdisciplinary Journal. 11, 1, p. 309-335 27 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
A multispecialty study of determining the possibility of pregnancy and the documentation of pregnancy status in surgical patients: a cause for concern?
Ibrahim, I., Ibrahim, B., Yong, G. L., Coats, M., Vujovic, Z. & Wilson, M. S. J., 1 Nov 2018, In: Scottish Medical Journal. 63, 4, p. 108-112 5 p.Research output: Contribution to journal › Article › peer-review
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A mutant O-GlcNAcase as a probe to reveal global dynamics of protein O-GlcNAcylation during Drosophila embryonic development
Mariappa, D., Selvan, N., Borodkin, V. S., Alonso, J., Ferenbach, A. T., Shepherd, C., Navratilova, I. H. & Van Aalten, D. M. F., Sep 2015, In: Biochemical Journal. 470, 2, p. 255-262 8 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
A mutant O-GlcNAcase enriches Drosophila developmental regulators
Selvan, N., Williamson, R., Mariappa, D., Campbell, D. G., Gourlay, R., Ferenbach, A. T., Aristotelous, T., Hopkins-Navratilova, I., Trost, M. & van Aalten, D. M. F., Aug 2017, In: Nature Chemical Biology. 13, 8, p. 882-887 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)199 Downloads (Pure) -
A mutual health service in Scotland: Do we understand fully the leadership implications?
Howieson, B. & Fenwick, C., Jul 2014, In: Leadership in Health Services. 27, 3, p. 193-203 11 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Anabolic resistance does not explain sarcopenia in patients with type 2 diabetes mellitus, compared with healthy controls, despite reduced mTOR pathway activity
Cuthbertson, D. J., Babraj, J., Leese, G. & Siervo, M., Dec 2017, In: Clinical Nutrition. 36, 6, p. 1716-1719 4 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
An active DNA-based nanoprobe for photoacoustic pH imaging
Baumann, K. N., Fux, A. C., Joseph, J., Bohndiek, S. E. & Hernández-Ainsa, S., 2018, In: Chemical Communications. 54, 72, p. 10176-10178 3 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)8 Downloads (Pure) -
An acute transfusion reaction
Webb, C., Norris, A. & Hands, K., 1 Feb 2018, In: Clinical Medicine - Journal of the Royal College of Physicians of London. 18, 1, p. 95-97 3 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
An adaptive IEEE 802.15.4 MAC layer transmission scheme for applications with heterogeneous traffic
Zhou, Y., He, J., Chen, K., Tang, Z. & Li, Y., Dec 2013, In: Information: An Interdisciplinary Journal in English, Japanese and Chinese . 16, 12 A, p. 8451-8456 6 p.Research output: Contribution to journal › Article › peer-review
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Anaesthesia for laryngo-tracheal surgery, including tubeless field techniques
Pearson, K. L. & McGuire, B. E., 1 Jul 2017, In: BJA Education. 17, 7, p. 242-248 7 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
An algorithm recommendation for the pharmacological management of allergic rhinitis in the UK: a consensus statement from an expert panel
Lipworth, B., Newton, J., Ram, B., Small, I. & Schwarze, J., 23 Jan 2017, In: NPJ Primary Care Respiratory Medicine. 27, p. 1-8 8 p., 3.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)169 Downloads (Pure) -
An alternate route to phosphorylating DegU of Bacillus subtilis using acetyl phosphate
Cairns, L. S., Martyn, J. E., Bromley, K. & Stanley-Wall, N. R., 31 Mar 2015, In: BMC Microbiology. 15, 12 p., 78.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
Analyses of groundwater flow and plant evapotranspiration in a vegetated soil slope
Leung, A. K. & Ng, C. W. W., Dec 2013, In: Canadian Geotechnical Journal. 50, 12, p. 1204-1218 15 p.Research output: Contribution to journal › Article › peer-review
44 Citations (Scopus) -
Analysis of a continuous finite element method for H(curl,div)-elliptic interface problem
Duan, H., Lin, P. & Tan, R. C. E., 2013, In: Numerische Mathematik. p. 1-37 37 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
Analysis of a model for banded vegetation patterns in semi-arid environments with nonlocal dispersal
Eigentler, L. & Sherratt, J. A., Sep 2018, In: Journal of Mathematical Biology. 77, 3, p. 739-763 25 p.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
Analysis of bender element test interpretation using the discrete element method
O’Donovan, J., O’Sullivan, C., Marketos, G. & Muir Wood, D., Apr 2015, In: Granular Matter. 17, 2, p. 197-216 20 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
Analysis of chain saw lubricating oils commonly used in Thailand's southern border provinces for forensic science purpose
Choodum, A., Tripuwanard, K. & Daeid, N. N., Aug 2014, In: Forensic Science International. 241, p. 60-68 9 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Analysis of coupled axial and lateral deformation of roots in soil
Meijer, G., Muir Wood, D., Knappett, J., Bengough, A. & Liang, T., 26 Oct 2018, In: International Journal for Numerical and Analytical Methods in Geomechanics. 33 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)197 Downloads (Pure) -
Analysis of Global RNA Synthesis at the Single Cell Level following Hypoxia
Biddlestone, J., Druker, J., Shmakova, A., Ferguson, G., Swedlow, J. R. & Rocha, S., 13 May 2014, In: JoVE: Journal of Visualized Experiments. 87, 7 p., e51420.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)171 Downloads (Pure) -
Analysis of hand pressures related to wheelchair rim sizes and upper-limb movement
Kabra, C., Jaiswal, R., Arnold, G., Abboud, R. & Wang, W., May 2015, In: International Journal of Industrial Ergonomics. 47, p. 45-52 8 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Analysis of Hopf/Hopf bifurcations in nonlocal hyperbolic models for self-organised aggregations
Buono, P-L. & Eftimie, R., Feb 2014, In: Mathematical Models and Methods in Applied Sciences. 24, 2, p. 327-357 31 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
Analysis of human protein replacement stable cell lines established using snoMEN-PR vector
Ono, M., Yamada, K., Endo, A., Avolio, F. & Lamond, A. I., 25 Apr 2013, In: PLoS ONE. 8, 4, 12 p., e62305.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)129 Downloads (Pure) -
Analysis of hyponatraemia associated post-operative mortality in 3897 hip fracture patients
Tinning, C. G., Cochrane, L. A. & Singer, B. R., 1 Jul 2015, In: Injury: the British Journal of Accident Surgery. 46, 7, p. 1328-1332 5 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
Analysis of joint force and torque for the human and non-human ape foot during bipedal walking with implications for the evolution of the foot
Wang, W., Abboud, R. J., Günther, M. M. & Crompton, R. H., Aug 2014, In: Journal of Anatomy. 25, 2, p. 152-166 15 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
Analysis of novel missense ATR mutations reveals new splicing defects underlying Seckel Syndrome
Llorens-Agost, M., Luessing, J., van Beneden, A., Eykelenboom, J., O'Reilly, D., Bicknell, L. S., Reynolds, J. J., van Koegelenberg, M., Hurles, M. E., Brady, A. F., Jackson, A. P., Stewart, G. S. & Lowndes, N. F., Dec 2018, In: Human Mutation. 39, 12, p. 1847-1853 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)121 Downloads (Pure) -
Analysis of phenotypic evolution in Dictyostelia highlights developmental plasticity as a likely consequence of colonial multicellularity
Romeralo, M., Skiba, A., Gonzalez-Voyer, A., Schilde, C., Lawal, H., Kedziora, S., Cavender, J. C., Gloeckner, G., Urushihara, H. & Schaap, P., 7 Aug 2013, In: Proceedings of the Royal Society B. 280, 1764, 9 p., 20130976.Research output: Contribution to journal › Article › peer-review
32 Citations (Scopus) -
Analysis of plant root-induced preferential flow and pore water pressure variation by a dual-permeability model
Shao, W., Ni, J., Leung, A. K., Su, Y. & Ng, C. W. W., 2017, In: Canadian Geotechnical Journal. 54, 11, p. 1537-1552 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Citations (Scopus)238 Downloads (Pure) -
Analysis of shared heritability in common disorders of the brain
Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., Malik, R., Patsopoulos, N. A., Ripke, S., Wei, Z., Yu, D., Lee, P. H., Turley, P., Grenier-Boley, B., Chouraki, V., Kamatani, Y., Berr, C. & 30 others, , 22 Jun 2018, In: Science. 360, 6395, p. 1-15 15 p., eaap8757.Research output: Contribution to journal › Article › peer-review
Open AccessFile475 Citations (Scopus)903 Downloads (Pure) -
Analysis of skeletal muscle has potential value in the assessment of cocaine-related deaths
Rees, K. A., Seulin, S., Yonamine, M., Leyton, V., Munoz, D. R., Gianvecchio, V. A. P., Pounder, D. J. & Osselton, M. D., 10 Mar 2013, In: Forensic Science International. 226, 1-3, p. 46-53 8 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
Analysis of susceptibility loci for nonsyndromic orofacial clefting in a European trio sample
Böhmer, A. C., Mangold, E., Tessmann, P., Mossey, P. A., Steegers-Theunissen, R. P., Lindemans, J., Bouwman-Both, M., Rubini, M., Franceschelli, P., Aiello, V., Peterlin, B., Molloy, A. M., Nöthen, M. M., Knapp, M. & Ludwig, K. U., Oct 2013, In: American Journal of Medical Genetics Part A. 161, 10, p. 2545-2549 5 p.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus)