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  Hypertension treatment for older people-navigating between Scylla and Charybdis

  Conroy, S. P., Westendorp, R. G. J. & Witham, M. D., Jul 2018, In: Age and Ageing. 47, 4, p. 505-508 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  18 Citations (Scopus)

  120 Downloads (Pure)

• Hypertensive Encephalopathy and Nephrotic Syndrome: a Possible Link?

  Pearson, E., D'Souza, R., Hamilton-Wood, C., Nicholls, A. J. & Beaman, M., 1 Jul 1999, In: Nephron Dialysis Transplantation. 14, 7, p. 1750-1752 3 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Hypertensive left ventricular hypertrophy: a mechanistic approach to optimizing regression assessed by cardiovascular magnetic resonance

  Burns, J., Ball, S. G., Worthy, G., Struthers, A. D., Mary, D. A. S. G. & Greenwood, J. P., Oct 2012, In: Journal of Hypertension. 30, 10, p. 2039-46 8 p.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)

• Hyperuricemia and adverse outcomes in cardiovascular disease: potential for therapeutic intervention

  Gavin, A. R. & Struthers, A. D., Sep 2003, In: American Journal of Cardiovascular Drugs. 3, 5, p. 309-314 6 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• Hyphenation can improve reading in acquired phonological dyslexia 1

  Harley, T. A. & O'Mara, D. A., 2006, In: Aphasiology. 20, 8, p. 744-761 18 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Hypoglycaemia: exercise for the brain?

  Ashford, M., Beall, C. & McCrimmon, R., Oct 2012, In: Journal of Neuroendocrinology. 24, 10, p. 1365-1366 2 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Hypoglycaemia, the most feared complication of insulin therapy

  McCrimmon, R. J. & Frier, B. M., 1994, In: Diabete et Metabolisme. 20, 6, p. 503-512 10 p.

  Research output: Contribution to journal › Article › peer-review
  98 Citations (Scopus)

• Hypoglycaemia events with iGlarLixi versus premix biphasic insulin aspart 30 (BIAsp 30) in people with type 2 diabetes advancing from basal insulin: An analysis of the SoliMix trial

  McCrimmon, R. J., Home, P., Cheng, A. Y. Y., Giorgino, F., Fonseca, V., Souhami, E., Alvarez, A., Picard, P. & Rosenstock, J., Dec 2022, In: Diabetes, Obesity and Metabolism. 24, 12, p. 2391-2399 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Hypoglycaemic symptoms reported by children with type 1 diabetes mellitus and by their parents

  Ross, L. A., McCrimmon, R. J., Frier, B. M., Kelnar, C. J. H. & Deary, I. J., Oct 1998, In: Diabetic Medicine. 15, 10, p. 836-843 8 p.

  Research output: Contribution to journal › Article › peer-review
  21 Citations (Scopus)

• Hypoglycemia and Clinical Outcomes in Hospitalized Patients With Diabetes: Does Association With Adverse Outcomes Remain When Number of Glucose Tests Performed Is Accounted For?

  Jones, G. C., Timmons, J. G., Cunningham, S. G., Cleland, S. J. & Sainsbury, C. A. R., Jul 2017, In: Journal of Diabetes Science and Technology. 11, 4, p. 720-723 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  6 Citations (Scopus)

• Hypoglycemia in Type 1 Diabetes

  McCrimmon, R. J. & Sherwin, R. S., Oct 2010, In: Diabetes. 59, 10, p. 2333-2339 7 p.

  Research output: Contribution to journal › Article › peer-review
  131 Citations (Scopus)

• Hypokalemic and ECG sequelae of combined beta-agonist/diuretic therapy: protection by conventional doses of spironolactone but not triamterene

  Lipworth, B. J., McDevitt, D. G. & Struthers, A. D., 1990, In: Chest. 98, 4, p. 811-815 5 p.

  Research output: Contribution to journal › Article › peer-review
  14 Citations (Scopus)

• Hypo-METRICS: Hypoglycaemia - MEasurement, ThResholds and ImpaCtS - A multi-country clinical study to define the optimal threshold and duration of sensor-detected hypoglycaemia that impact the experience of hypoglycaemia, quality of life and health economic outcomes: the study protocol

  Divilly, P., Zaremba, N., Mahmoudi, Z., Søholm, U., Pollard, D. J., Broadley, M., Abbink, E. J., de Galan, B., Pedersen-Bjergaard, U., Renard, E., Evans, M., Speight, J., Brennan, A., McCrimmon, R. J., Müllenborn, M., Heller, S., Seibold, A., Mader, J. K., Amiel, S. A., Pouwer, F., & 2 othersChoudhary, P. & Hypo-RESOLVE Consortium, Sep 2022, In: Diabetic Medicine. 39, 9, 11 p., e14892.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  2 Citations (Scopus)

  46 Downloads (Pure)

• Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(+/-) mice

  Bayascas, J. R., Leslie, N., Parsons, R., Fleming, S. & Alessi, D., Oct 2005, In: Current Biology. 15, 20, p. 1839-1846 8 p.

  Research output: Contribution to journal › Article › peer-review
  130 Citations (Scopus)

• Hypomorphic promoter mutation in PIGM causes inherited glycosylphosphatidylinositol deficiency

  Almeida, A. M., Murakami, Y., Layton, D. M., Hillmen, P., Sellick, G. S., Maeda, Y., Richards, S., Patterson, S., Kotsianidis, I., Mollica, L., Crawford, D. H., Baker, A., Ferguson, M., Roberts, I., Houlston, R., Kinoshita, T. & Karadimitris, A., Jul 2006, In: Nature Medicine. 12, 7, p. 846-851 6 p.

  Research output: Contribution to journal › Article › peer-review
  183 Citations (Scopus)

• Hypophosphorylation of Mdm2 augments p53 stability

  Blattner, C., Hay, T., Meek, D. W. & Lane, D. P., Sep 2002, In: Molecular and Cellular Biology. 22, 17, p. 6170-6182 13 p.

  Research output: Contribution to journal › Article › peer-review
  126 Citations (Scopus)

• Hypophysitis induced by immune checkpoint inhibitors in a Scottish melanoma population: Immune checkpoint inhibitor toxicity

  Wei, K. Z., Baxter, M. & Casasola, R., 18 Apr 2019, In: Melanoma Management. 6, 1, 12 p., MMT13.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  108 Downloads (Pure)

• Hyporesponsiveness to alpha-adrenoceptor agonists in cirrhotic patients is not evident when human hepatic and mesenteric arteries are studied in vitro

  Hadoke, P. W. F., Dillon, J. F., Walker, S. W., Williams, B. C., John, T. G. & Hayes, P. C., Apr 1996, In: British Journal of Pharmacology. 117, S1, p. 111p-111p 1 p.

  Research output: Contribution to journal › Article › peer-review

• Hypothalamic AMP-activated protein kinase activation with AICAR amplifies counterregulatory responses to hypoglycemia in a rodent model of type 1 diabetes

  Fan, X., Ding, Y., Brown, S., Zhou, L., Shaw, M., Vella, M. C., Cheng, H., Mcnay, E. C., Sherwin, R. S. & McCrimmon, R., 2009, In: American Journal of Physiology - Regulatory, Integrative and Comparative Physiology (AJP - Regulatory, Integrative and Comparative Physiology) . 296, 6, p. R1702-R1708 7 p.

  Research output: Contribution to journal › Article › peer-review
  37 Citations (Scopus)

• Hypothalamic ATP-sensitive K + channels play a key role in sensing hypoglycemia and triggering counterregulatory epinephrine and glucagon responses

  Evans, M. L., McCrimmon, R. J., Flanagan, D. E., Keshavarz, T., Fan, X., McNay, E. C., Jacob, R. J. & Sherwin, R. S., Oct 2004, In: Diabetes. 53, 10, p. 2542-2551 10 p.

  Research output: Contribution to journal › Article › peer-review
  134 Citations (Scopus)

• Hypothalamic Fkbp51 is induced by fasting, and elevated hypothalamic expression promotes obese phenotypes

  Yang, L., Isoda, F., Yen, K., Kleopoulos, S. P., Janssen, W., Fan, X., Mastaitis, J., Dunn-Meynell, A., Levin, B., McCrimmon, R., Sherwin, R., Musatov, S. & Mobbs, C. V., 2012, In: AJP - Endocrinology and Metabolism (Endocrinology and Metabolism. 302, 8, p. E987-E991 5 p.

  Research output: Contribution to journal › Article › peer-review
  22 Citations (Scopus)

• Hypothesis: persistent expression of fetal phenotypic characteristics by fibroblasts is associated with an increased susceptibility to neoplastic disease

  Schor, S. L., Schor, A. M., Howell, A. & Crowther, D., 1987, In: Experimental cell biology. 55, 1, p. 11-7 7 p.

  Research output: Contribution to journal › Article › peer-review
  36 Citations (Scopus)

• Hypothesis and preliminary data to suggest carbon monoxide as the mediator of the hyperdynamic circulation of cirrhosis?

  Dillon, J. F., Selby, C., Hadoke, P. W. F., Therapondos, G., Mohaddin, S., Walker, S. W. & Hayes, P. C., Dec 1998, In: Medical Biochemistry. 1, 1, p. 93-96 4 p.

  Research output: Contribution to journal › Article › peer-review

  1 Citation (Scopus)

• Hypothetical economic analysis of screening for left ventricular hypertrophy in high-risk normotensive populations

  Witham, M. D., Davies, J. I., Dawson, A., Davey, P. G. & Struthers, A. D., 2004, In: QJM : an International Journal of Medicine. 97, 2, p. 87-93 7 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• 'Hypothetical facts' and the balance of probabilities

  Symon, A., 1 Jan 2007, In: British Journal of Midwifery. 15, 3, p. 171-172 2 p.

  Research output: Contribution to journal › Article › peer-review

• Hypoxemia during diagnostic laparoscopy: A prospective study

  Haydon, G. H., Dillon, J., Simpson, K. J., Thomas, H. & Hayes, P. C., 1 Jan 1996, In: Gastrointestinal Endoscopy. 44, 2, p. 124-128 5 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Hypoxia activates IKK-NF-κB and the immune response in Drosophila melanogaster

  Bandarra, D., Biddlestone, J., Mudie, S., Muller, H. A. & Rocha, S., 2014, In: Bioscience Reports. 34, 4, p. 429-440 12 p., e00127.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  26 Citations (Scopus)

  181 Downloads (Pure)

• Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism

  Watts, E. R., Howden, A. J. M., Morrison, T., Sadiku, P., Hukelmann, J. L., von Kriegsheim, A., Ghesquière, B., Murphy, F., Mirchandani, A. S., Humphries, D. C., Grecian, R., Ryan, E. M., Coelho, P., Rodriguez-Blanco, G., Plant, T. M., Dickinson, R. S., Finch, A. J., Vermaelen, W., Cantrell, D. A., Whyte, M. K. B., & 1 othersWalmsley, S. R., 17 May 2021, In: Journal of Clinical Investigation. 131, 10, 17 p., e134073.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  7 Citations (Scopus)

  46 Downloads (Pure)

• Hypoxia Induced NF-κB

  D'Ignazio, L. & Rocha, S., 8 Mar 2016, In: Cells. 5, 1, 8 p., 10.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  86 Citations (Scopus)

  141 Downloads (Pure)

• Hypoxia induces rapid changes to histone methylation and reprograms chromatin

  Batie, M., Frost, J., Frost, M., Wilson, J. W., Schofield, P. & Rocha, S., 15 Mar 2019, In: Science. 363, 6432, p. 1222-1226 5 p.

  Research output: Contribution to journal › Article › peer-review
  162 Citations (Scopus)

• Hypoxia-inducible factor 1α is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif

  Land, S. C. & Tee, A. R., Jul 2007, In: Journal of Biological Chemistry. 282, 28, p. 20534-20543 10 p.

  Research output: Contribution to journal › Article › peer-review
  400 Citations (Scopus)

• Hypoxia inhibits human recombinant large conductance, Ca²⁺-activated K⁺ (maxi-K) channels by a mechanism which is membrane delimited and Ca²⁺ sensitive

  Lewis, A., Peers, C., Ashford, M. L. J. & Kemp, P. J., 1 May 2002, In: Journal of Physiology. 540, 3, p. 771-780 10 p.

  Research output: Contribution to journal › Article › peer-review
  70 Citations (Scopus)

• Hypoxia is not the primary mechanism contributing to exercise-induced proteinuria

  Joyce, K. E., Delamere, J., Bradwell, S., Myers, S. D., Ashdown, K., Rue, C., Lucas, S. J. E., Thomas, O. D., Fountain, A., Edsell, M., Myers, F., Malein, W., Imray, C., Clarke, A., Lewis, C. T., Newman, C., Johnson, B., Cadigan, P., Wright, A. & Bradwell, A., 26 Mar 2020, In: BMJ Open Sport and Exercise Medicine. 6, 1, p. 1-10 10 p., e000662.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  2 Citations (Scopus)

  39 Downloads (Pure)

• Hypoxia-mediated control of HIF/ARNT machinery in epidermal keratinocytes

  Weir, L., Robertson, D., Leigh, I. M., Vass, J. K. & Panteleyev, A. A., Jan 2011, In: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1813, 1, p. 60-72 13 p.

  Research output: Contribution to journal › Article › peer-review
  28 Citations (Scopus)

• Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation

  Mirchandani, A. S., Jenkins, S. J., Bain, C. C., Sanchez-Garcia, M. A., Lawson, H., Coelho, P., Murphy, F., Griffith, D. M., Zhang, A., Morrison, T., Ly, T., Arienti, S., Sadiku, P., Watts, E. R., Dickinson, R. S., Reyes, L., Cooper, G., Clark, S., Lewis, D., Kelly, V., & 22 othersSpanos, C., Musgrave, K. M., Delaney, L., Harper, I., Scott, J., Parkinson, N. J., Rostron, A. J., Baillie, J. K., Clohisey, S., Pridans, C., Campana, L., Lewis, P. S., Simpson, A. J., Dockrell, D. H., Schwarze, J., Hirani, N., Ratcliffe, P. J., Pugh, C. W., Kranc, K., Forbes, S. J., Whyte, M. K. B. & Walmsley, S. R., Jun 2022, In: Nature Immunology. 23, p. 927-939 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  5 Citations (Scopus)

  2 Downloads (Pure)

• Hypoxic activation of an amiloride-sensitive cation conductance in alveolar epithelial cells

  Jovanovic, S., Land, S. C., Olver, R. E. & Wilson, S. M., 2001, In: Biochemical and Biophysical Research Communications. 286, 3, p. 622-7 6 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Hypoxic pulmonary vasoconstriction: mechanisms of oxygen-sensing

  Evans, A. M., Hardie, D. G., Peers, C. & Mahmoud, A., Feb 2011, In: Current Opinion in Anaesthesiology. 24, 1, p. 13-20 8 p.

  Research output: Contribution to journal › Article › peer-review
  51 Citations (Scopus)

• Hysteresis and non-uniqueness in the speed of the onset of instability in curtain coating

  Marston, J. O., Decent, S. P. & Simmons, M. J. H., Dec 2006, In: Journal of Fluid Mechanics. 569, p. 349-363 15 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Hysteretic Implications for Graded Bed Load Transport in Symmetrical Hydrograph Flows

  Wang, L., Wang, D., Cuthbertson, A., Zhong, D. & Pender, G., 24 Dec 2021, In: Frontiers in Environmental Science. 9, 14 p., 800832.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  20 Downloads (Pure)

• Hysteroscopic and laparoscopic management of caesarean scar (niche) defects in symptomatic patients

  Brown, K. & Tkacz, Z., Jul 2018, In: Journal of Obstetrics & Gynaecology. 38, 5, p. 730 1 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• I. Luxembourg, Brussels and now the Hague: Congestion in the promotion of free movement in parental responsibility matters

  McEleavy, P., 2010, In: International and Comparative Law Quarterly. 59, 2, p. 505-519 15 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Ian Kennedy Artist Interview

  Vaughan, P., Apr 2013, In: Studies in Comics. 4, 1, p. 15-33 19 p.

  Research output: Contribution to journal › Article › peer-review

• Ian Paisley's facing into a possible by-election ... he can be heartened by his likely re-election

  Muinzer, T., 14 Sep 2018, thejournal.ie.

  Research output: Contribution to specialist publication › Article

• Iatrogenic profound hypoalphalipoproteinemia: an unrecognized cause of very-low hdl cholesterol

  Murphy, M. J., Duncan, A., Vallance, B. D., Packard, C. J. & O'Reilly, D. S. J., 1 Aug 1995, In: Postgraduate Medical Journal. 71, 838, p. 498-500 3 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Iatrogenic sexual dysfunction and the protective withholding of information: in whose best interest?

  Barker, P., Begley, C. M. & Higgins, A., Aug 2006, In: Journal of Psychiatric and Mental Health Nursing. 13, 4, p. 437-446 10 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes

  Momozawa, Y., Dmitrieva, J., Théâtre, E., Deffontaine, V., Rahmouni, S., Charloteaux, B., Crins, F., Docampo, E., Elansary, M., Gori, A. S., Lecut, C., Mariman, R., Mni, M., Oury, C., Altukhov, I., Alexeev, D., Aulchenko, Y., Amininejad, L., Bouma, G., Hoentjen, F., & 15 othersLöwenberg, M., Oldenburg, B., Pierik, M. J., Vander Meulen-De Jong, A. E., Van Der Woude, C. J., Visschedijk, M. C., Lathrop, M., Hugot, J. P., Weersma, R. K., De Vos, M., Franchimont, D., Vermeire, S., Kubo, M., Louis, E. & Georges, M., 21 Jun 2018, In: Nature Communications. 9, 1, p. 1-18 18 p., 2427.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  100 Citations (Scopus)

  84 Downloads (Pure)

• IBMPFD disease-causing mutant VCP/p97 proteins are targets of autophagic-lysosomal degradation

  Bayraktar, O., Oral, O., Kocaturk, N. M., Akkoc, Y., Eberhart, K., Kosar, A. & Gozuacik, D., 21 Oct 2016, In: PLoS ONE. 11, 10, 19 p., e0164864.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  24 Citations (Scopus)

  36 Downloads (Pure)

• IC261, a specific inhibitor of the protein kinases casein kinase 1-delta and -epsilon, triggers the mitotic checkpoint and induces p53-dependent postmitotic effects

  Behrend, L., Milne, D. M., Stöter, M., Deppert, W., Campbell, L. E., Meek, D. W. & Knippschild, U., 2000, In: Oncogene. 19, 47, p. 5303-5313 11 p.

  Research output: Contribution to journal › Article › peer-review
  104 Citations (Scopus)

• ICBS & ECBS Chemical Biology Meeting 2015 - Let them come to Berlin!

  Komatsu, T. & Virdee, S., 20 May 2016, In: ACS Chemical Biology. 11, 5, p. 1159-1166 8 p.

  Research output: Contribution to journal › Article

  Open Access

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  3 Citations (Scopus)

  136 Downloads (Pure)

• "ICDAS"--an international system for caries detection and assessment being developed to facilitate caries epidemiology, research and appropriate clinical management

  Pitts, N., 2004, In: Community Dental Health. 21, 3, p. 193-8 6 p.

  Research output: Contribution to journal › Article › peer-review
  314 Citations (Scopus)