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A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis
Naeem, A. S., Tommasi, C., Cole, C., Brown, S. J., Zhu, Y., Way, B., Willis Owen, S. A. G., Moffatt, M., Cookson, W. O., Harper, J. I., Di, W. L., Brown, S. J., Reinheckel, T. & O'Shaughnessy, R. F. L., Apr 2017, In: Journal of Allergy and Clinical Immunology. 139, 4, p. 1228-1241 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)217 Downloads (Pure) -
A method for automatic segmentation and splitting of hyperspectral images of raspberry plants collected in field conditions
Williams, D., Britten, A., McCallum, S., Jones, H., Aitkenhead, M., Karley, A., Loades, K., Prashar, A. & Graham, J., 1 Nov 2017, In: Plant Methods. 13, p. 1-12 12 p., 74.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)175 Downloads (Pure) -
A Method to Evaluate Trainee Progression During Simulation Training at the Urology Simulation Boot Camp (USBC) Course
Kailavasan, M., Hanchanale, V., Rajpal, S., Morley, R., Mcllhenny, C., Somani, B., Nabi, G., Gowda, R., Jain, S., Biyani, C. S. & Myatt, A., Jan 2019, In: Journal of Surgical Education. 76, 1, p. 215-222 8 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies
Bodea, C. A., Neale, B. M., Ripke, S., International IBD Genetics Consortium, Daly, M. J., Devlin, B. & Roeder, K., 5 May 2016, In: American Journal of Human Genetics. 98, 5, p. 857-868 12 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
A minimally invasive tool to study immune response and skin barrier in children with atopic dermatitis
Hulshof, L., Hack, D. P., Hasnoe, Q. C. J., Dontje, B., Jakasa, I., Riethmüller, C., McLean, W. H. I., van Aalderen, W. M. C., Van't Land, B., Kezic, S., Sprikkelman, A. B. & Middelkamp-Hup, M. A., Mar 2019, In: British Journal of Dermatology. 180, 3, p. 621-630 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)148 Downloads (Pure) -
A minimum data set approach to post-mortem computed tomography reporting for anthropological biological profiling
Brough, A. L., Morgan, B., Robinson, C., Black, S., Cunningham, C., Adams, C. & Rutty, G. N., Dec 2014, In: Forensic Science, Medicine and Pathology. 10, 4, p. 504-512 9 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
Amino acid neurotoxins in feathers of the Lesser Flamingo, Phoeniconaias minor
Metcalf, J. S., Banack, S. A., Kotut, K., Krienitz, L. & Codd, G. A., Jan 2013, In: Chemosphere. 90, 2, p. 835-839 5 p.Research output: Contribution to journal › Article › peer-review
24 Citations (Scopus) -
Amino acid secretion influences the size and composition of copper carbonate nanoparticles synthesized by ureolytic fungi
Liu, F., Csetenyi, L. & Gadd, G., Sep 2019, In: Applied Microbiology and Biotechnology. 103, 17, p. 7217-7230 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)110 Downloads (Pure) -
Amino acid substitutions in the human homomeric β3 GABAA receptor that enable activation by GABA
Gottschald Chiodi, C., Baptista-Hon, D., Hunter, W. & Hales, T., 15 Feb 2019, In: Journal of Biological Chemistry. 294, 7, p. 2375-2385 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)119 Downloads (Pure) -
Aminoglycosides restore full-length type VII collagen by overcoming premature termination codons: therapeutic implications for dystrophic epidermolysis bullosa
Cogan, J., Weinstein, J., Wang, X., Hou, Y., Martin, S., South, A. P., Woodley, D. T. & Chen, M., 23 Jul 2014, In: Molecular Therapy. 22, 10, p. 1741-1752 12 p.Research output: Contribution to journal › Article › peer-review
37 Citations (Scopus) -
A missense mutation in the catalytic domain of O-GlcNAc transferase links perturbations in protein O-GlcNAcylation to X-linked intellectual disability
Pravata, V. M., Gundogdu, M., Bartual, S. G., Ferenbach, A. T., Stavridis, M., Õunap, K., Pajusalu, S., Žordania, R., Wojcik, M. H. & van Aalten, D. M. F., 7 Nov 2019, In: FEBS Letters. 594, 4, p. 717-727 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)14 Downloads (Pure) -
A Mixed Analytical/Numerical Method for Velocity and Heat Transfer of Laminar Power-Law Fluids
Li, B., Zheng, L., Lin, P., Wang, Z. & Liao, M., 3 Aug 2016, In: Numerical Mathematics: Theory, Methods and Applications. 9, 3, p. 315-336 22 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
A mobile phone intervention to reduce binge drinking among disadvantaged men: study protocol for a randomised controlled cost-effectiveness trial
Crombie, I. K., Irvine, L., Williams, B., Sniehotta, F. F., Petrie, D., Evans, J. M. M., Emslie, C., Jones, C., Ricketts, I. W., Humphris, G., Norrie, J., Rice, P. & Slane, P. W., 19 Dec 2014, In: Trials. 15, 8 p., 494.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)169 Downloads (Pure) -
A model based criterion for gene expression calls using RNA-seq data
Wagner, G. P., Kin, K. & Lynch, V. J., Sep 2013, In: Theory in Biosciences. 132, 3, p. 159-164 6 p.Research output: Contribution to journal › Article › peer-review
77 Citations (Scopus) -
A Model for (Quasi-)Periodic Multiwavelength Photometric Variability in Young Stellar Objects
Kesseli, A. Y., Petkova, M. A., Wood, K., Whitney, B. A., Hillenbrand, L. A., Gregory, S. G., Stauffer, J. R., Morales-Calderon, M., Rebull, L. & Alencar, S. H. P., Sep 2016, In: Astrophysical Journal. 828, 1, p. 1-15 15 p., 42.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)84 Downloads (Pure) -
A model for dynamic reconfiguration in service-oriented architectures
Fiadeiro, J. L. & Lopes, A., 1 May 2013, In: Software and Systems Modeling. 12, 2, p. 349-367 19 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
A model of consultation in prostate cancer care: evidence from a systematic review
Paterson, C. & Nabi, G., 2017, In: Cancer Nursing. 40, 4, p. 276-288 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)400 Downloads (Pure) -
A model of the transformative journey into reflexivity: an exploration into students' experiences of critical reflection
Shaw, R., 15 Feb 2013, In: Reflective Practice. 14, 3, p. 319-335 17 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
A modified Delphi process to establish future research priorities in malignant oesophagogastric surgery
Wilson, M. S. J., Blencowe, N. S., Boyle, C., Knight, S. R., Petty, R., Vohra, R. S. & Underwood, T. J., 16 Dec 2019, In: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 6 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
A molecular explanation for the recessive nature of parkin-linked Parkinson's disease
Spratt, D. E., Julio Martinez-Torres, R., Noh, Y. J., Mercier, P., Manczyk, N., Barber, K. R., Aguirre, J. D., Burchell, L., Purkiss, A., Walden, H. & Shaw, G. S., 1 Jan 2013, In: Nature Communications. 4, 12 p., 1983.Research output: Contribution to journal › Article › peer-review
88 Citations (Scopus) -
A More Scientific Approach to Applied Economics: Reconstructing Statistical, Analytical Significance, and Correlation Analysis
Altman, M., 28 Feb 2019, In: SSRN Working Paper Series. 23 p.Research output: Contribution to journal › Article
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A Morphological identification cell cytotoxicity assay using cytoplasm-localized fluorescent probe (CLFP) to distinguish living and dead cells
Lai, F., Shen, Z., Wen, H., Chen, J., Zhang, X., Lin, P., Yin, D., Cui, H. & Chen, X., 8 Jan 2017, In: Biochemical and Biophysical Research Communications. 482, 2, p. 257-263 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)409 Downloads (Pure) -
A mouse model for functional dissection of TAB1 O-GlcNAcylation
Authier, F., Muha, V. & van Aalten, D. M. F., 27 Aug 2019, In: Wellcome Open Research. 4, 16 p., 128.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
A moving interface finite element formulation for layered structures
Funari, M. F., Greco, F. & Lonetti, P., 1 Jul 2016, In: Composites Part B: Engineering. 96, p. 325-337 13 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
AMP-activated protein kinase: a cellular energy sensor that comes in twelve flavours
Ross, F. A., MacKintosh, C. & Hardie, D. G., 24 Mar 2016, In: FEBS Journal. 283, 16, p. 2987-3001 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile138 Citations (Scopus)114 Downloads (Pure) -
AMP-activated protein kinase (AMPK)α2 plays a role in determining the cellular fate of glucose in insulin-resistant mouse skeletal muscle
Lee-Young, R. S., Bonner, J. S., Mayes, W. H., Iwueke, I., Barrick, B. A., Hasenour, C. M., Kang, L. & Wasserman, D. H., Mar 2013, In: Diabetologia. 56, 3, p. 608-617 10 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner
Vlachaki Walker, J. M., Robb, J. L., Cruz, A. M., Malhi, A., Weightman Potter, P. G., Ashford, M. L. J., McCrimmon, R. J., Ellacott, K. L. J. & Beall, C., 21 Apr 2017, In: Diabetes, Obesity & Metabolism. 19, 7, p. 997-1005 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)294 Downloads (Pure) -
AMP-activated protein kinase inhibits Kv1.5 channel currents of pulmonary arterial myocytes in response to hypoxia and inhibition of mitochondrial oxidative phosphorylation
Moral-Sanz, J., Mahmoud, A. D., Ross, F. A., Eldstrom, J., Fedida, D., Hardie, D. G. & Evans, A. M., 1 Sep 2016, In: Journal of Physiology. 594, 17, p. 4901-4915 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)162 Downloads (Pure) -
Amphiphilic oxygenated amorphous carbon-graphite buckypapers with gas sensitivity to polar and non-polar VOCs
Homaeigohar, S., Sep 2019, In: Nanomaterials. 9, 9, p. 1-14 14 p., 1343.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)17 Downloads (Pure) -
AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation
Gowans, G. J., Hawley, S. A., Ross, F. A. & Hardie, D. G., 1 Oct 2013, In: Cell Metabolism. 18, 4, p. 556-566 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile275 Citations (Scopus)163 Downloads (Pure) -
AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?
Dandapani, M. & Hardie, D. G., Apr 2013, In: Biochemical Society Transactions. 41, 2, p. 687-693 7 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
AMPK: regulating energy balance at the cellular and whole body levels
Hardie, D. G. & Ashford, M. L. J., Mar 2014, In: Physiology. 29, 2, p. 99-107 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile162 Citations (Scopus)165 Downloads (Pure) -
AMPK: a target for drugs and natural products with effects on both diabetes and cancer
Hardie, D. G., Jul 2013, In: Diabetes. 62, 7, p. 2164-2172 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile264 Citations (Scopus)137 Downloads (Pure) -
AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B
Johanns, M., Lai, Y. C., Hsu, M. F., Jacobs, R., Vertommen, D., Van Sande, J., Dumont, J. E., Woods, A., Carling, D., Hue, L., Viollet, B., Foretz, M. & Rider, M. H., 8 Mar 2016, In: Nature Communications. 7, 10856.Research output: Contribution to journal › Article › peer-review
Open Access56 Citations (Scopus) -
AMPK Causes Cell Cycle Arrest in LKB1-deficient Cells via Activation of CAMKK2
Fogarty, S., Ross, F. A., Vara Ciruelos, D., Gray, A., Gowans, G. J. & Hardie, D. G., 1 Aug 2016, In: Molecular Cancer Research. 14, 8, p. 683-695 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Citations (Scopus)317 Downloads (Pure) -
AMPK modulates glucose-sensing in insulin-secreting cells by altered phosphotransfer to KATP channels
Beall, C., Watterson, K. R., McCrimmon, R. J. & Ashford, M. L. J., Jun 2013, In: Journal of Bioenergetics and Biomembranes. 45, 3, p. 229-241 13 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
AMPK-sensing energy while talking to other signaling pathways
Hardie, D. G., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 939-952 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile317 Citations (Scopus)159 Downloads (Pure) -
AMPKα1: a glucose sensor that controls CD8 T-cell memory
Rolf, J., Zarrouk, M., Finlay, D. K., Foretz, M., Viollet, B. & Cantrell, D. A., Apr 2013, In: European Journal of Immunology. 43, 4, p. 889-896 8 p.Research output: Contribution to journal › Article › peer-review
138 Citations (Scopus) -
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
LifeLines Cohort Study, Sung, Y. J., de Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D. & 40 others, , 1 Aug 2019, In: Human Molecular Genetics. 28, 15, p. 2615-2633 19 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)68 Downloads (Pure) -
A Multicenter, Randomized, Placebo-Controlled Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients With Rheumatoid Arthritis: A multicenter, randomized, placebo controlled trial
Kitas, G. D., Nightingale, P., Armitage, J., Sattar, N., Belch, J. J. F. & Symmons, D. P. M., Sep 2019, In: Arthritis and Rheumatology. 71, 9, p. 1437-1449 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile31 Citations (Scopus)43 Downloads (Pure) -
A multicentre parallel-group randomised trial assessing multiparametric MRI characterisation and image-guided biopsy of prostate in men suspected of having prostate cancer: MULTIPROS study protocol
Szewczyk-Bieda, M., Wei, C., Coll, K., Gandy, S., Donnan, P., Ragupathy, S. K. A., Singh, P., Wilson, J. & Nabi, G., 21 Nov 2019, In: Trials. 20, p. 1-8 8 p., 638.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)75 Downloads (Pure) -
A Multi-disciplinary Approach to the Archaeological Investigation of a Bedrock-Dominated Shallow-Marine Landscape: An example from the Bay of Firth, Orkney, UK
Bates, M. R., Nayling, N., Bates, R., Dawson, S., Huws, D. & Wickham-Jones, C., Mar 2013, In: International Journal of Nautical Archaeology. 42, 1, p. 24-43 20 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
A multidisciplinary intervention to reduce antibiotic duration in lower respiratory tract infections
Murray, C., Shaw, A., Lloyd, M., Smith, R. P., Fardon, T. C., Schembri, S. & Chalmers, J. D., Feb 2014, In: Journal of Antimicrobial Chemotherapy. 69, 2, p. 515-518 4 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13
Leslie, E. J., Carlson, J. C., Shaffer, J. R., Feingold, E., Wehby, G., Laurie, C. A., Jain, D., Laurie, C. C., Doheny, K. F., McHenry, T., Resick, J., Sanchez, C., Jacobs, J., Emanuele, B., Vieira, A. R., Neiswanger, K., Lidral, A. C., Valencia-Ramirez, L. C., Lopez-Palacio, A. M., Valencia, D. R. & 35 others, , 1 Jul 2016, In: Human Molecular Genetics. 25, 13, p. 2862-2872 11 p.Research output: Contribution to journal › Article › peer-review
86 Citations (Scopus) -
A multifaceted intervention to improve sepsis management in general hospital wards with evaluation using segmented regression of interrupted time series
Marwick, C. A., Guthrie, B., Pringle, J. E. C., Evans, J. M. M., Nathwani, D., Donnan, P. T. & Davey, P. G., Dec 2014, In: BMJ Quality & Safety. 23, 12, 8 p., e2.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
A multimodal approach to cardiovascular risk stratification in patients with type 2 diabetes incorporating retinal, genomic and clinical features
Fetit, A., Doney, A., Hogg, S., Wang, R., MacGillivray, T., Wardlaw, J. M., Doubal, F. N., McKay, G. J., McKenna, S. & Trucco, E., 5 Mar 2019, In: Scientific Reports. 9, 10 p., 3591.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)138 Downloads (Pure) -
A multiscale mathematical model of tumour invasive growth
Peng, L., Trucu, D., Lin, P., Thompson, A. & Chaplain, M. A. J., Mar 2017, In: Bulletin of Mathematical Biology. 79, 3, p. 389-429 41 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)177 Downloads (Pure) -
A multiscale moving boundary model arising in cancer invasion
Trucu, D., Lin, P., Chaplain, M. A. J. & Wang, Y., 2013, In: Multiscale Modeling and Simulation: A SIAM Interdisciplinary Journal. 11, 1, p. 309-335 27 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
A mutant O-GlcNAcase enriches Drosophila developmental regulators
Selvan, N., Williamson, R., Mariappa, D., Campbell, D. G., Gourlay, R., Ferenbach, A. T., Aristotelous, T., Hopkins-Navratilova, I., Trost, M. & van Aalten, D. M. F., Aug 2017, In: Nature Chemical Biology. 13, 8, p. 882-887 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)199 Downloads (Pure) -
A mutual health service in Scotland: Do we understand fully the leadership implications?
Howieson, B. & Fenwick, C., Jul 2014, In: Leadership in Health Services. 27, 3, p. 193-203 11 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus)