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• Article

  Adverse respiratory effect of acute beta-blocker exposure in asthma: a systematic review and meta-analysis of randomized controlled trials

  Morales, D. R., Jackson, C., Lipworth, B. J., Donnan, P. T. & Guthrie, B., Apr 2014, In: Chest. 145, 4, p. 779-786

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Meta-Analysis
  • Systematic Reviews
  • Randomized Controlled Trials
  • Celiprolol
  59 Citations (Scopus)

• Asthma Step-Down Strategies: Perhaps the Patient Should Decide?

  Lipworth, B. & Israel, E., Mar 2018, In: The Journal of Allergy and Clinical Immunology: In Practice. 6, 2, p. 644-645 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  153 Downloads (Pure)

• Current appraisal of single inhaler triple therapy in COPD

  Lipworth, B., Kuo, R. W. & Jabbal, S., 28 Sep 2018, In: International Journal of Chronic Obstructive Pulmonary Disease. 13, 13, p. 3003-3009 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Muscarinic Antagonists
  • Nebulizers and Vaporizers
  • Chronic Obstructive Pulmonary Disease
  • Adrenal Cortex Hormones
  • fluticasone furoate
  17 Citations (Scopus)

  174 Downloads (Pure)

• Disconnection of pulmonary and systemic arterial stiffness in COPD

  Weir-McCall, J. R., Liu-Shiu-Cheong, P. S., Struthers, A. D., Lipworth, B. J. & Houston, J. G., 28 May 2018, In: International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 1755-1765 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Vascular Stiffness
  • Chronic Obstructive Pulmonary Disease
  • Pulse Wave Analysis
  • Lung
  • Healthy Volunteers
  1 Citation (Scopus)

  166 Downloads (Pure)

• Effects of contrast administration on cardiac MRI volumetric, flow and pulse wave velocity quantification using manual and software-based analysis

  Fathi, A., Weir-McCall, J. R., Struthers, A. D., Lipworth, B. J. & Houston, J. G., 2018, In: British Journal of Radiology. 91, 1084, 14 p., 20170717.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pulse Wave Analysis
  • Gadolinium
  • Software
  • Contrast Media
  • gadoterate meglumine
  3 Citations (Scopus)

  196 Downloads (Pure)

• Effects of intravenous and oral β-blockade in persistent asthmatics controlled on inhaled corticosteroids

  Short, P. M., Anderson, W. J., Williamson, P. A. & Lipworth, B. J., Feb 2014, In: Heart (British Cardiac Society). 100, 3, p. 219-223 5 p.

  Research output: Contribution to journal › Article › peer-review

  • esmolol
  • Propranolol
  • Adrenal Cortex Hormones
  • Asthma
  • Cardiovascular Diseases
  15 Citations (Scopus)

• Impact of long-acting bronchodilators and exposure to inhaled corticosteroids on mortality in COPD: a real-life retrospective cohort study

  Manoharan, A., Short, P. M., Anderson, W. J. & Lipworth, B. J., Oct 2014, In: Lung. 192, 5, p. 649-652 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Bronchodilator Agents
  • Chronic Obstructive Pulmonary Disease
  • Muscarinic Antagonists
  • Adrenal Cortex Hormones
  • Cohort Studies
  12 Citations (Scopus)

• Improved lung function and patient-reported outcomes with co-suspension delivery technology glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a randomized Phase III study conducted in Asia, Europe, and the USA

  Lipworth, B. J., Collier, D. J., Gon, Y., Zhong, N., Nishi, K., Chen, R., Arora, S., Maes, A., Siddiqui, S., Reisner, C. & Martin, U. J., 26 Sep 2018, In: International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 2969-2984 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glycopyrrolate
  • Formoterol Fumarate
  • Metered Dose Inhalers
  • Patient Reported Outcome Measures
  • Chronic Obstructive Pulmonary Disease
  21 Citations (Scopus)

  149 Downloads (Pure)

• Influence of β2-adrenergic receptor polymorphism on methacholine hyperresponsiveness in asthmatic patients

  Manoharan, A., Anderson, W. J. & Lipworth, B. J., Mar 2013, In: Annals of Allergy, Asthma & Immunology. 110, 3, p. 161-164 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Methacholine Chloride
  • Adrenergic Receptors
  • Haplotypes
  • Genotype
  • Asthma
  5 Citations (Scopus)

• Inhaled and Systemic Corticosteroid Response in Severe Asthma Assessed by Alveolar Nitric Oxide: a randomised crossover pilot study of add-on therapy

  Williamson, P. A., Short, P. M., Vaidyanathan, S. & Lipworth, B. J., Jan 2013, In: British Journal of Clinical Pharmacology. 75, 1, p. 93-102 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Cross-Over Studies
  • Nitric Oxide
  • Adrenal Cortex Hormones
  • Asthma
  • Budesonide
  12 Citations (Scopus)

• Lack of clinically relevant differences between combination therapy and monotherapy in COPD

  Lipworth, B. J., Apr 2014, In: European Respiratory Journal. 43, 4, p. 1204 1 p.

  Research output: Contribution to journal › Article › peer-review

• Left Ventricular Hypertrophy in COPD Without Hypoxemia: The Elephant in the Room?

  Anderson, W. J., Lipworth, B. J., Rekhraj, S., Struthers, A. D. & George, J., Jan 2013, In: Chest. 143, 1, p. 91-97 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Left Ventricular Hypertrophy
  • Chronic Obstructive Pulmonary Disease
  • Hypoxia
  • Brain Natriuretic Peptide
  • Blood Pressure
  23 Citations (Scopus)

• Proof of concept evaluation of trough airway hyper-responsiveness following regular racemic or levosalbutamol in genotype-stratified steroid-treated persistent asthmatic patients

  Anderson, W. J., Short, P. M., Williamson, P. A., Morrison, A. E., Palmer, C., Tavendale, R. & Lipworth, B. J., 1 Jan 2014, In: Clinical Science. 126, 1, p. 75-83 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Respiratory Hypersensitivity
  • Proof of Concept Study
  • Albuterol
  • Steroids
  • Genotype
  3 Citations (Scopus)

• Pulmonary and systemic arterial stiffness are disconnected in COPD

  Weir-McCall, J., Liu Shiu Cheong, P., Struthers, A., Lipworth, B. & Houston, J., 28 May 2018, In: International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 1755-1765 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Vascular Stiffness
  • Chronic Obstructive Pulmonary Disease
  • Lung
  • Healthy Volunteers
  • Biomarkers

• Pulmonary arterial stiffening in COPD and its implications for right ventricular remodelling.

  Weir-McCall, J. R., Liu Shiu Cheong, P. S. K., Struthers, A. D., Lipworth, B. J. & Houston, J. G., Aug 2018, In: European Radiology. 28, 8, p. 3464-3472 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ventricular Remodeling
  • Chronic Obstructive Pulmonary Disease
  • Pulse Wave Analysis
  • Lung
  • Stroke Volume
  3 Citations (Scopus)

  238 Downloads (Pure)

• Randomised Placebo-controlled Trial to Evaluate Chronic Dosing Effects of Propranolol in Asthma

  Short, P. M., Williamson, P. A., Anderson, W. J. & Lipworth, B. J., 15 Jun 2013, In: American Journal of Respiratory and Critical Care Medicine. 187, 12, p. 1308-1314 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Propranolol
  • Methacholine Chloride
  • Asthma
  • Placebos
  • Randomized Controlled Trials
  40 Citations (Scopus)

• Relationship of large and small airway response with inhaled corticosteroid to asthma control

  Manoharan, A., Anderson, W. J. & Lipworth, B. J., Aug 2013, In: Annals of Allergy, Asthma & Immunology. 111, 2, p. 140-142 3 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Safety risks for patients with aspirin-exacerbated respiratory disease after acute exposure to selective nonsteroidal anti-inflammatory drugs and COX-2 inhibitors: meta-analysis of controlled clinical trials

  Morales, D. R., Lipworth, B. J., Guthrie, B., Jackson, C., Donnan, P. T. & Santiago, V. H., Jul 2014, In: Journal of Allergy and Clinical Immunology. 134, 1, p. 40-45.e10 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclooxygenase 2 Inhibitors
  • Controlled Clinical Trials
  • Acute Disease
  • Patient Safety
  • Aspirin
  44 Citations (Scopus)

• Sensitivity of lung resistance and compliance to beta-blocker induced bronchoconstriction and long acting beta-agonist withdrawal in COPD

  Jabbal, S. & Lipworth, B. J., Feb 2018, In: Lung. 196, 1, p. 15-18 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Carvedilol
  • Lung Compliance
  • Bronchoconstriction
  • Oscillometry
  • Chronic Obstructive Pulmonary Disease
  3 Citations (Scopus)

  162 Downloads (Pure)

• Small airway dysfunction is associated with poorer asthma control

  Manoharan, A., Anderson, W. J., Lipworth, J., Ibrahim, I. & Lipworth, B. J., Nov 2014, In: European Respiratory Journal. 44, 5, p. 1353-1355 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  30 Citations (Scopus)

  144 Downloads (Pure)

• Tadalafil in patients with chronic obstructive pulmonary disease: a randomised, double-blind, parallel-group, placebo-controlled trial

  Goudie, A. R., Lipworth, B. J., Hopkinson, P. J., Wei, L. & Struthers, A. D., Apr 2014, In: The Lancet Respiratory Medicine. 2, 4, p. 293-300 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Tadalafil
  • Chronic Obstructive Pulmonary Disease
  • Placebos
  • Dyspepsia
  • Quality of Life
  60 Citations (Scopus)

  177 Downloads (Pure)

• Tailored second-line therapy in asthmatic children with the Arg16 genotype

  Lipworth, B. J., Basu, K., Donald, H. P., Tavendale, R., MacGregor, D. F., Ogston, S. A., Palmer, C. N. A. & Mukhopadhyay, S., Apr 2013, In: Clinical Science. 124, 8, p. 521-528 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Salmeterol Xinafoate
  • montelukast
  • Genotype
  • Child
  • Precision Medicine
  54 Citations (Scopus)

• Targeting the small airways asthma phenotype: if we can reach it, should we treat it?

  Lipworth, B., Apr 2013, In: Annals of Allergy, Asthma & Immunology. 110, 4, p. 233-239 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Nebulizers and Vaporizers
  • Asthma
  • Technology
  • Phenotype
  • Therapeutics
  29 Citations (Scopus)

• The inverse agonist propranolol confers no corticosteroid-sparing activity in mild-to-moderate persistent asthma

  Anderson, W. J., Short, P. M., Williamson, P. A., Manoharan, A. & Lipworth, B. J., Dec 2014, In: Clinical Science. 127, 11, p. 635-643 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Propranolol
  • Adrenal Cortex Hormones
  • Asthma
  • apaflurane
  • Beclomethasone
  13 Citations (Scopus)

• The potential role of direct and indirect bronchial challenge testing to identify overtreatment of community managed asthma

  Manoharan, A., Lipworth, B., Craig, E. & Jackson, C., Oct 2014, In: Clinical and Experimental Allergy. 44, 10, p. 1240-1245 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Medical Overuse
  • Asthma
  • Methacholine Chloride
  • Mannitol
  • Medical Informatics
  13 Citations (Scopus)

• Toll-like receptor 3 blockade in rhinovirus-induced experimental asthma exacerbations: A Randomized Controlled Study

  Silkoff, P. E., Flavin, S., Gordon, R., Loza, M. J., Sterk, P. J., Lutter, R., Diamant, Z., Turner, R. B., Lipworth, B. J., Proud, D., Singh, D., Eich, A., Backer, V., Gern, J. E., Herzmann, C., Halperin, S. A., Mensinga, T. T., Del Vecchio, A. M., Branigan, P., San Mateo, L. & 3 others, Baribaud, F., Barnathan, E. S. & Johnston, S. L., Apr 2018, In: Journal of Allergy and Clinical Immunology. 141, 4, p. 1220-1230 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Toll-Like Receptor 3
  • Rhinovirus
  • Asthma
  • Placebos
  • Healthy Volunteers
  18 Citations (Scopus)

  224 Downloads (Pure)

• Unlocking the quiet zone: the small airway asthma phenotype

  Lipworth, B., Manoharan, A. & Anderson, W., 2014, In: The Lancet Respiratory Medicine. 2, 6, p. 497-506 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Phenotype
  • Nebulizers and Vaporizers
  • Lung
  • Adrenal Cortex Hormones
  67 Citations (Scopus)

• β-Adrenoceptor genotype and bronchoprotective subsensitivity with long-acting β-agonists in asthma

  Lipworth, B., 15 Dec 2013, In: American Journal of Respiratory and Critical Care Medicine. 188, 12, p. 1386-1387 2 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)
• Letter

  Adrenal suppression with fluticasone furoate

  Lipworth, B. J., Mar 2013, In: Annals of Allergy, Asthma & Immunology. 110, 3, p. 213

  Research output: Contribution to journal › Letter › peer-review

• Adrenal suppression with inhaled corticosteroids: the seed and the soil

  Lipworth, B., Kuo, C. & Jabbal, S., 1 Jun 2018, In: The Lancet Respiratory Medicine. 6, 6, p. e19 1 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File
  1 Citation (Scopus)

  190 Downloads (Pure)

• Adrenal suppression with mometasone furoate/formoterol

  Lipworth, B. J., May 2014, In: Chest. 145, 5, p. 1175-1176 2 p.

  Research output: Contribution to journal › Letter › peer-review

• Adverse effects of long-acting Beta-agonists on airway hyperresponsiveness

  Lipworth, B., Manoharan, A. & Short, P., Sep 2013, In: American Journal of Respiratory Cell and Molecular Biology. 49, 3, p. 501-502 2 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Citation (Scopus)

• Anti-interleukin 13 for asthma: stick or twist?

  Lipworth, B., Jabbal, S. & Kuo, C. R., Sep 2018, In: The Lancet Respiratory Medicine. 6, 9, p. e46-e47 2 p.

  Research output: Contribution to journal › Letter › peer-review
  3 Citations (Scopus)

• Author response

  Lipworth, B., Sep 2013, In: Annals of Allergy, Asthma & Immunology. 111, 3, p. 234 1 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Citation (Scopus)

• Does the asthma visual analogue scale relate to the asthma control questionnaire?

  Jabbal, S. & Lipworth, B., 1 May 2018, In: Annals of Allergy, Asthma & Immunology. 120, 5, p. 533-535 3 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File

  • Visual Analog Scale
  • Asthma
  • Documentation
  • Guidelines
  123 Downloads (Pure)

• Explaining differential effects of tiotropium on mortality in COPD

  Lipworth, B. J. & Short, P., 2013, In: Thorax. 68, 6, p. 589-590 2 p.

  Research output: Contribution to journal › Letter › peer-review
  3 Citations (Scopus)

• Influence of β₂-adrenoceptor 16 genotype on propranolol-induced bronchoconstriction in patients with persistent asthma

  Anderson, W. J., Short, P. M., Manoharan, A., Lipworth, J. L. R. & Lipworth, B. J., 2014, In: Annals of Allergy, Asthma & Immunology. 112, 5, p. 475-476 2 p.

  Research output: Contribution to journal › Letter › peer-review
  4 Citations (Scopus)

• Inhaled triple therapy in chronic obstructive pulmonary disease

  Lipworth, B., Kuo, C. R. W. & Jabbal, S., 29 Sep 2018, In: The Lancet. 392, 10153, p. 1112-1113 2 p.

  Research output: Contribution to journal › Letter › peer-review

• Is small airways dysfunction related to asthma control and type 2 inflammation?

  Kuo, C. R., Jabbal, S. & Lipworth, B., Nov 2018, In: Annals of Allergy, Asthma & Immunology. 121, 5, p. 631-632 2 p.

  Research output: Contribution to journal › Letter › peer-review
  4 Citations (Scopus)

• Reply: pharmacological obfuscation of clinical relevance

  Lipworth, B., Short, P., Anderson, W. & Williamson, P., 1 Feb 2014, In: American Journal of Respiratory and Critical Care Medicine. 189, 3, p. 360-361 2 p.

  Research output: Contribution to journal › Letter › peer-review
  2 Citations (Scopus)

• Systemic safety of fluticasone furoate/vilanterol combination

  Lipworth, B., Dec 2013, In: Thorax. 68, 12, p. 1165

  Research output: Contribution to journal › Letter › peer-review
  2 Citations (Scopus)

• Uncorrected nitric oxide levels in mild asthmatics produce flawed interpretation

  Lipworth, B., Nov 2013, In: Journal of Allergy and Clinical Immunology. 132, 5, p. 1255 1 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Citation (Scopus)
• Review article

  Emerging role of long acting muscarinic antagonists for asthma

  Lipworth, B. J., Jan 2014, In: British Journal of Clinical Pharmacology. 77, 1, p. 55-62 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Muscarinic Antagonists
  • Asthma
  • Adrenal Cortex Hormones
  • Respiratory Hypersensitivity
  • Airway Management
  25 Citations (Scopus)

• What can we learn about COPD from impulse oscillometry?

  Lipworth, B. J. & Jabbal, S., 1 Jun 2018, In: Respiratory Medicine. 139, p. 106-109 4 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Oscillometry
  • Chronic Obstructive Pulmonary Disease
  • Bronchoconstriction
  • Airway Resistance
  • Bronchodilator Agents
  17 Citations (Scopus)

  225 Downloads (Pure)