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  • Diana Vara Ciruelos

AMP-Activated Protein Kinase: Friend or Foe in Cancer

Vara-ciruelos, D., Dandapani, M. & Hardie, D. G., 4 Mar 2020, In : Annual Review of Cancer Biology. 4, p. 1-16 16 p.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
29 Downloads (Pure)

AMPK Causes Cell Cycle Arrest in LKB1-deficient Cells via Activation of CAMKK2

Fogarty, S., Ross, F. A., Vara Ciruelos, D., Gray, A., Gowans, G. J. & Hardie, D. G., 1 Aug 2016, In : Molecular Cancer Research. 14, 8, p. 683-695 13 p.

Research output: Contribution to journalArticle

Open Access
File
32 Citations (Scopus)
303 Downloads (Pure)

Genotoxic Damage Activates the AMPK-α1 Isoform in the Nucleus via Ca2+/CaMKK2 Signaling to Enhance Tumor Cell Survival

Vara Ciruelos, D., Dandapani, M., Gray, A., Agbani, E. O., Evans, A. M. & Hardie, D. G., Feb 2018, In : Molecular Cancer Research. 16, 2, p. 345-357 13 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
143 Downloads (Pure)

Phenformin, but not metformin, delays development of T-cell acute lymphoblastic leukemia/lymphoma via cell-autonomous AMPK activation

Vara Ciruelos, D., Dandapani, M., Russell, F. M., Grzes, K., Atrih, A., Foretz, M., Viollet, B., Lamont, D. J., Cantrell, D. A. & Hardie, D. G., 16 Apr 2019, In : Cell Reports. 27, 3, p. 690-698.e4 15 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
131 Downloads (Pure)

Targeting AMP-activated kinase impacts hepatocellular cancer stem cells induced by long-term treatment with sorafenib

Bort, A., Sánchez, B. G., Mateos-Gómez, P. A., Vara-Ciruelos, D., Rodríguez-Henche, N. & Díaz-Laviada, I., May 2019, In : Molecular Oncology. 13, 5, p. 1311-1331 21 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
120 Downloads (Pure)

The cannabinoid WIN 55,212-2 prevents neuroendocrine differentiation of LNCaP prostate cancer cells

Morell, C., Bort, A., Vara, D., Ramos-Torres, A., Rodríguez-Henche, N. & Díaz-Laviada, I., Sep 2016, In : Prostate Cancer and Prostatic Diseases. 19, 3, p. 248-258 10 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
162 Downloads (Pure)

The strange case of AMPK and cancer: Dr Jekyll or Mr Hyde?

Vara-Ciruelos, D., Russell, F. M. & Hardie, D. G., 10 Jul 2019, In : Open Biology. 9, 7, p. 1-21 21 p., 190099.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
93 Downloads (Pure)

Up-regulated expression of LAMP2 and autophagy activity during neuroendocrine differentiation of prostate cancer LNCaP cells

Morell, C., Bort, A., Vara-Ciruelos, D., Ramos-Torres, Á., Altamirano-Dimas, M., Díaz-Laviada, I. & Rodríguez-Henche, N., 14 Sep 2016, In : PLoS ONE. 11, 9, p. 1-24 24 p., e0162977.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
172 Downloads (Pure)