Find Research Outputs

Search results

• World Health Organization essential medicines lists: where are the drugs to treat neuropathic pain?

  Kamerman, P. R., Wadley, A. L., Davis, K. D., Hietaharju, A., Jain, P., Kopf, A., Meyer, A-C., Raja, S. N., Rice, A. S. C., Smith, B. H., Treede, R-D. & Wiffen, P. J., May 2015, In: Pain. 156, 5, p. 793-797 5 p.

  Research output: Contribution to journal › Article › peer-review
  23 Citations (Scopus)

• Variants associated with HHIP expression have sex-differential effects on lung function

  Smith, B. H., 1 Jun 2020, In: Wellcome Open Research. 5, p. 1-14 14 p., 111.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Hedgehog Proteins
  • Lung
  • Forced Expiratory Volume
  • Proteins
  • Polymorphism
  19 Downloads (Pure)

• Trends in gabapentinoid prescribing, co-prescribing of opioids and benzodiazepines, and associated deaths in Scotland

  Torrance, N., Veluchamy, A., Zhou, Y., Fletcher, E., Moir, E., Hebert, H., Donnan, P., Watson, J., Colvin, L. & Smith, B. H., Aug 2020, In: British Journal of Anaesthesia. 125, 2, p. 159-167 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Scotland
  • Benzodiazepines
  • Opioid Analgesics
  • Prescriptions
  • Pregabalin
  1 Citation (Scopus)

• Translating clinical trials into improved real-world management of pain: Convergence of translational, population-based and primary care research

  Gilron, I., Blyth, F. M. & Smith, B., Jan 2020, In: Pain. 161, 1, p. 36-42 7 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File
  19 Downloads (Pure)

• Training peers to support older people with chronic low back pain following physiotherapy discharge: a feasibility study

  Cooper, K., Mary Jehu, L., Klein, S., Smith, B. H. & Schofield, P., Jun 2018, In: Physiotherapy. 104, 2, p. 239-247 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Feasibility Studies
  • Low Back Pain
  • Volunteers
  • Self-Management
  • Education
  3 Citations (Scopus)

  276 Downloads (Pure)

• The effect of Stanford-type self-management programmes on pain and function in older people with persistent pain

  Martin, D., Schofield, P., Jones, D., McNamee, P., Clarke, A., Anthony, G. & Smith, B., 1 Jan 2013, Pain: International Research in Pain Management. Nova Science Publishers, p. 165-172 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • pain
  • management
  • lack
  • evidence

• The effect of stanford-type self-management programmes on pain and function in older people with persistent pain: A systematic review of randomised controlled trials

  Martin, D., Schofield, P., Jones, D., McNamee, P., Clarke, A., Anthony, G. & Smith, B., 8 Oct 2013, In: Journal of Pain Management. 6, 2, p. 117-122 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Self-Management
  • Systematic Reviews
  • Randomized Controlled Trials
  • Pain
  • Language
  2 Citations (Scopus)

• Systematic review and meta-analysis of genetic risk factors for neuropathic pain

  Veluchamy, A., Hébert, H. L., Meng, W., Palmer, C. N. A. & Smith, B. H., May 2018, In: Pain. 159, 5, p. 825-848 24 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Neuralgia
  • Meta-Analysis
  • Systematic Reviews
  • HLA-A Antigens
  • HLA-DQB1 antigen
  16 Citations (Scopus)

  300 Downloads (Pure)

• Substance misuse in patients who have comorbid chronic pain in a clinical population receiving methadone maintenance therapy for the treatment of opioid dependence

  Higgins, C., Smith, B. & Matthews, K., 1 Dec 2018, In: Drug and Alcohol Dependence. 193, p. 131-136 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Opioid-Related Disorders
  • Cannabinoids
  • Methadone
  • Benzodiazepines
  • Chronic Pain
  4 Citations (Scopus)

  98 Downloads (Pure)

• Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose

  Wu, P., Rybin, D., Bielak, L. F., Feitosa, M. F., Franceschini, N., Li, Y., Lu, Y., Marten, J., Musani, S. K., Noordam, R., Raghavan, S., Rose, L. M., Schwander, K., Smith, A. V., Tajuddin, S. M., Vojinovic, D., Amin, N., Arnett, D. K., Bottinger, E. P., Demirkan, A. & 38 others, Florez, J. C., Ghanbari, M., Harris, T. B., Launer, L. J., Liu, J., Liu, J., Mook-Kanamori, D. O., Murray, A. D., Nalls, M. A., Peyser, P. A., Uitterlinden, A. G., Voortman, T., Bouchard, C., Chasman, D., Correa, A., de Mutsert, R., Evans, M. K., Gudnason, V., Hayward, C., Kao, L., Kardia, S. L. R., Kooperberg, C., Loos, R. J. F., Province, M. M., Rankinen, T., Redline, S., Ridker, P. M., Rotter, J. I., Siscovick, D., Smith, B. H., van Duijn, C., Zonderman, A. B., Rao, D. C., Wilson, J. G., Dupuis, J., Meigs, J. B., Liu, C-T. & Vassy, J. L., 7 May 2020, In: PLoS ONE. 15, 5, p. 1-17 17 p., e0230815.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • noninsulin-dependent diabetes mellitus
  • Medical problems
  • fasting
  • Fasting
  • Type 2 Diabetes Mellitus
  2 Citations (Scopus)

  24 Downloads (Pure)

• Sex-differences in the metabolic health of offspring of parents with diabetes: a record-linkage study

  Aldhous, M. C., Reynolds, R. M., Campbell, A., Linksted, P., Lindsay, R. S., Smith, B. H., Seckl, J. R., Porteous, D. J., Norman, J. E. & Generation Scotland, 26 Aug 2015, In: PLoS ONE. 10, 8, 18 p., e0134883.

  Research output: Contribution to journal › Article › peer-review

  • records (publications)
  • Medical problems
  • diabetes
  • gender differences
  • Sex Characteristics
  10 Citations (Scopus)

• Sex-and Age-Specific Genetic Analysis of Chronic Back Pain

  Freidin, M. B., Tsepilov, Y. A., Stanaway, I. B., Meng, W., Hayward, C., Smith, B. H., Khoury, S., Parisien, M., Bortsov, A., Diatchenko, L., Børte, S., Winsvold, B. S., Brumpton, B. M., Zwart, J-A., Aulchenko, Y. S., Suri, P. & Williams, F. M. K., 5 Oct 2020, In: Pain.

  Research output: Contribution to journal › Article › peer-review

  • Back Pain
  • Chronic Pain
  • Single Nucleotide Polymorphism
  • Chromosomes, Human, Pair 10
  • Intervertebral Disc Degeneration

• Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

  Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P. & 31 others, Flannick, J., Grarup, N., Trubetskoy, V. V., Kravic, J., Kim, Y. J., Rybin, D. V., Yaghootkar, H., Müller-Nurasyid, M., Meidtner, K., Li-Gao, R., Varga, T. V., Marten, J., Li, J., Smith, A. V., An, P., Ligthart, S., Gustafsson, S., Malerba, G., Demirkan, A., Tajes, J. F., Steinthorsdottir, V., Wuttke, M., Lecoeur, C., Preuss, M., Bielak, L. F., Graff, M., Highland, H. M., Morris, A. D., Smith, B. H., Palmer, C. N. A. & ExomeBP Consortium, 9 Apr 2018, In: Nature Genetics. 50, 4, p. 559-571 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Type 2 Diabetes Mellitus
  • Multifactorial Inheritance
  • Causality
  • Genome
  • Odds Ratio
  113 Citations (Scopus)

  365 Downloads (Pure)

• Predictors of QTc and QTc prolongation in the Generation Scotland Family Study

  Brown, C. E., Hastie, C. E., Alghamdi, J., Schulz, C., Hocking, L. J., Luciano, M., Porteous, D., Morris, A., Smith, B. H., Dominiczak, A. F., Tobias, E. S., Delles, C. & Padmanabhan, S., 2013, In: Journal of Human Hypertension. 27, 10, p. 639-639 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis

  Finnerup, N. B., Attal, N., Haroutounian, S., McNicol, E., Baron, R., Dworkin, R. H., Gilron, I., Haanpää, M., Hansson, P., Jensen, T. S., Kamerman, P. R., Lund, K., Moore, A., Raja, S. N., Rice, A. S. C., Rowbotham, M., Sena, E., Siddall, P., Smith, B. H. & Wallace, M., Feb 2015, In: Lancet Neurology. 14, 2, p. 162-173 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuralgia
  • Meta-Analysis
  • Systematic Reviews
  • Drug Therapy
  • Tramadol
  1377 Citations (Scopus)

• Pharmacist-led management of chronic pain in primary care: costs and benefits in a pilot randomised controlled trial

  Neilson, A. R., Bruhn, H., Bond, C. M., Elliott, A. M., Smith, B. H., Hannaford, P. C., Holland, R., Lee, A. J., Watson, M., Wright, D. & McNamee, P., 1 Apr 2015, In: BMJ Open. 5, 4, 11 p., e006874.

  Research output: Contribution to journal › Article › peer-review

  • Pharmacists
  • Chronic Pain
  • Cost-Benefit Analysis
  • Primary Health Care
  • Quality-Adjusted Life Years
  13 Citations (Scopus)

• Pharmacist-led management of chronic pain in primary care: results from a randomised controlled exploratory trial

  Bruhn, H., Bond, C. M., Elliott, A. M., Hannaford, P. C., Lee, A. J., McNamee, P., Smith, B. H., Watson, M. C., Holland, R. & Wright, D., 2013, In: BMJ Open. 3, 4, e002361.

  Research output: Contribution to journal › Article › peer-review

  • Pharmacists
  • Chronic Pain
  • Primary Health Care
  • Randomized Controlled Trials
  • Anxiety
  52 Citations (Scopus)

• Perioperative management of patients with suspected or confirmed COVID-19: review and recommendations for perioperative management from a retrospective cohort study

  Zheng, H., Hébert, H. L., Chatziperi, A., Meng, W., Smith, B. H., Yan, J., Zhou, Z., Zhang, X., Luo, A., Wang, L., Zhu, W., Hu, J. & Colvin, L. A., Dec 2020, In: British Journal of Anaesthesia. 125, 6, p. 895-911 17 p.

  Research output: Contribution to journal › Review article › peer-review

  • Coronavirus
  • Cohort Studies
  • Retrospective Studies
  • Personal Protective Equipment
  • Health Personnel

• Pedigree and genotyping quality analyses of over 10,000 DNA samples from the Generation Scotland: Scottish Family Health Study

  Kerr, S. M., Campbell, A., Murphy, L., Hayward, C., Jackson, C., Wain, L. V., Tobin, M. D., Dominiczak, A., Morris, A., Smith, B. H. & Porteous, D. J., 22 Mar 2013, In: BMC Medical Genetics. 14, 38.

  Research output: Contribution to journal › Article › peer-review

  • Family Health
  • Scotland
  • Pedigree
  • Single Nucleotide Polymorphism
  • DNA
  31 Citations (Scopus)

• PALS: peer support for community dwelling older people with chronic low back pain: a feasibility and acceptability study

  Cooper, K., Schofield, P., Smith, B. H. & Klein, S., Mar 2020, In: Physiotherapy (United Kingdom). 106, p. 154-162 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Feasibility Studies
  • Independent Living
  • Low Back Pain
  • Volunteers
  • Outcome Assessment (Health Care)
  2 Citations (Scopus)

  136 Downloads (Pure)

• Out of Hours: My personal diagnostic delay

  Smith, B. H., 1 Apr 2015, In: British Journal of General Practice. 65, 633, p. 200 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • Physicians

• Neuropathic pain phenotyping by international consensus (NeuroPPIC) for genetic studies: a NeuPSIG systematic review, Delphi survey, and expert panel recommendations

  van Hecke, O., Kamerman, P. R., Attal, N., Baron, R., Bjornsdottir, G., Bennett, D. L. H., Bennett, M. I., Bouhassira, D., Diatchenko, L., Freeman, R., Freynhagen, R., Haanpää, M., Jensen, T. S., Raja, S. N., Rice, A. S. C., Seltzer, Z., Thorgeirsson, T. E., Yarnitsky, D. & Smith, B. H., Nov 2015, In: Pain. 156, 11, p. 2337-2353 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuralgia
  • Consensus
  • Systematic Reviews
  • Phenotype
  • Pain
  35 Citations (Scopus)

• Neuropathic pain in the community: prevalence, impact and risk factors

  Smith, B. H., Hebert, H. L. & Veluchamy, A., 1 Sep 2020, In: Pain. 161, Supplement 1, p. S127-S137 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuralgia
  • Primary Health Care
  • Direction compound
  • Psychology
  • Quality of Life

• Neuropathic pain in the community: more under-treated than refractory?

  Torrance, N., Ferguson, J. A., Afolabi, E., Bennett, M. I., Serpell, M. G., Dunn, K. M. & Smith, B. H., May 2013, In: Pain. 154, 5, p. 690–699 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuralgia
  • Chronic Pain
  • Pain
  • Self Efficacy
  • Signs and Symptoms
  95 Citations (Scopus)

• Neuropathic pain clinical trials: factors associated with decreases in estimated drug efficacy

  Finnerup, N. B., Haroutounian, S., Baron, R., Dworkin, R. H., Gilron, I., Haanpaa, M. L., Jensen, T. S., Kamerman, P. R., McNicol, E., Moore, A., Raja, S. N., Andersen, N. T., Sena, E., Smith, B., Rice, A. S. C. & Attal, N., 1 Nov 2018, In: Pain. 159, 11, p. 2339-2346 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Neuralgia
  • Clinical Trials
  • Numbers Needed To Treat
  • Pain
  • Pharmaceutical Preparations
  19 Citations (Scopus)

  94 Downloads (Pure)

• Neuropathic pain: a pathway for care developed by the British Pain Society

  Smith, B. H., Lee, J., Price, C. & Baranowski, A. P., Jul 2013, In: British Journal of Anaesthesia. 111, 1, p. 73-79 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuralgia
  • Pain
  • Secondary Care
  • Tertiary Healthcare
  • Consensus
  25 Citations (Scopus)

• Multi-ethnic genome-wide association study for atrial fibrillation

  Roselli, C., Chaffin, M. D., Weng, L-C., Aeschbacher, S., Ahlberg, G., Albert, C. M., Almgren, P., Alonso, A., Anderson, C. D., Aragam, K. G., Arking, D. E., Barnard, J., Bartz, T. M., Benjamin, E. J., Bihlmeyer, N. A., Bis, J. C., Bloom, H. L., Boerwinkle, E., Bottinger, E. B., Brody, J. A. & 197 others, Calkins, H., Campbell, A., Cappola, T. P., Carlquist, J., Chasman, D. I., Chen, L. Y., Chen, Y-D. I., Choi, E-K., Choi, S. H., Christophersen, I. E., Chung, M. K., Cole, J. W., Conen, D., Cook, J., Crijns, H. J., Cutler, M. J., Damrauer, S. M., Daniels, B. R., Darbar, D., Delgado, G., Denny, J. C., Dichgans, M., Dörr, M., Dudink, E. A., Dudley, S. C., Esa, N., Esko, T., Eskola, M., Fatkin, D., Felix, S. B., Ford, I., Franco, O. H., Geelhoed, B., Grewal, R. P., Gudnason, V., Guo, X., Gupta, N., Gustafsson, S., Gutmann, R., Hamsten, A., Harris, T. B., Hayward, C., Heckbert, S. R., Hernesniemi, J., Hocking, L. J., Hofman, A., Horimoto, A. R. V. R., Huang, J., Huang, P. L., Huffman, J., Ingelsson, E., Ipek, E. G., Ito, K., Jimenez-Conde, J., Jukema, J. W., Kääb, S., Kähönen, M., Kamatani, Y., Kane, J. P., Kastrati, A., Kathiresan, S., Katschnig-Winter, P., Kavousi, M., Kessler, T., Kietselaer, B. L., Kirchhof, P., Kleber, M. E., Knight, S., Krieger, J. E., Kubo, M., Launer, L. J., Laurikka, J., Lehtimäki, T., Leineweber, K., Lemaitre, R. N., Li, M., Lim, H. E., Lin, H. J., Lin, H., Lind, L., Lindgren, C. M., Lokki, M-L., London, B., Loos, R. J. F., Low, S-K., Lu, Y., Lyytikäinen, L-P., Macfarlane, P. W., Magnusson, P. K., Mahajan, A., Malik, R., Mansur, A. J., Marcus, G. M., Margolin, L., Margulies, K. B., März, W., McManus, D. D., Melander, O., Mohanty, S., Montgomery, J. A., Morley, M. P., Morris, A. P., Müller-Nurasyid, M., Natale, A., Nazarian, S., Neumann, B., Newton-Cheh, C., Niemeijer, M. N., Nikus, K., Nilsson, P., Noordam, R., Oellers, H., Olesen, M. S., Orho-Melander, M., Padmanabhan, S., Pak, H-N., Paré, G., Pedersen, N. L., Pera, J., Pereira, A., Porteous, D., Psaty, B. M., Pulit, S. L., Pullinger, C. R., Rader, D. J., Refsgaard, L., Ribasés, M., Ridker, P. M., Rienstra, M., Risch, L., Roden, D. M., Rosand, J., Rosenberg, M. A., Rost, N., Rotter, J. I., Saba, S., Sandhu, R. K., Schnabel, R. B., Schramm, K., Schunkert, H., Schurman, C., Scott, S. A., Seppälä, I., Shaffer, C., Shah, S., Shalaby, A. A., Shim, J., Shoemaker, M. B., Siland, J. E., Sinisalo, J., Sinner, M. F., Slowik, A., Smith, A. V., Smith, B. H., Smith, J. G., Smith, J. D., Smith, N. L., Soliman, E. Z., Sotoodehnia, N., Stricker, B. H., Sun, A., Sun, H., Svendsen, J. H., Tanaka, T., Tanriverdi, K., Taylor, K. D., Teder-Laving, M., Teumer, A., Thériault, S., Trompet, S., Tucker, N. R., Tveit, A., Uitterlinden, A. G., van der Harst, P., Van Gelder, I. C., Van Wagoner, D. R., Verweij, N., Vlachopoulou, E., Völker, U., Wang, B., Weeke, P. E., Weijs, B., Weiss, R., Weiss, S., Wells, Q. S., Wiggins, K. L., Wong, J. A., Woo, D., Worrall, B. B., Yang, P-S., Yao, J., Yoneda, Z. T., Zeller, T., Zeng, L., Lubitz, S. A., Lunetta, K. L. & Ellinor, P. T., 11 Jun 2018, In: Nature Genetics. 50, 9, p. 1225-1233 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Genome-Wide Association Study
  • Atrial Fibrillation
  • Meta-Analysis
  • Quantitative Trait Loci
  • Genes
  136 Citations (Scopus)

  331 Downloads (Pure)

• Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

  Ntalla, I., Weng, L., Cartwright, J. H., Hall, A. W., Sveinbjornsson, G., Tucker, N. R., Choi, S. H., Chaffin, M. D., Roselli, C., Barnes, M. R., Mifsud, B., Warren, H. R., Hayward, C., Marten, J., Cranley, J. J., Concas, M. P., Gasparini, P., Boutin, T., Kolcic, I., Polasek, O. & 167 others, Rudan, I., Araujo, N. M., Lima-costa, M. F., Ribeiro, A. L. P., Souza, R. P., Tarazona-santos, E., Giedraitis, V., Ingelsson, E., Mahajan, A., Morris, A. P., Del Greco M, F., Foco, L., Gögele, M., Hicks, A. A., Cook, J. P., Lind, L., Lindgren, C. M., Sundström, J., Nelson, C. P., Riaz, M. B., Samani, N. J., Sinagra, G., Ulivi, S., Kähönen, M., Mishra, P. P., Mononen, N., Nikus, K., Caulfield, M. J., Dominiczak, A., Padmanabhan, S., Montasser, M. E., O’connell, J. R., Ryan, K., Shuldiner, A. R., Aeschbacher, S., Conen, D., Risch, L., Thériault, S., Hutri-kähönen, N., Lehtimäki, T., Lyytikäinen, L., Raitakari, O. T., Barnes, C. L. K., Campbell, H., Joshi, P. K., Wilson, J. F., Isaacs, A., Kors, J. A., Van Duijn, C. M., Huang, P. L., Gudnason, V., Harris, T. B., Launer, L. J., Smith, A. V., Bottinger, E. P., Loos, R. J. F., Nadkarni, G. N., Preuss, M. H., Correa, A., Mei, H., Wilson, J., Meitinger, T., Müller-nurasyid, M., Peters, A., Waldenberger, M., Mangino, M., Spector, T. D., Rienstra, M., Van De Vegte, Y. J., Van Der Harst, P., Verweij, N., Kääb, S., Schramm, K., Sinner, M. F., Strauch, K., Cutler, M. J., Fatkin, D., London, B., Olesen, M., Roden, D. M., Benjamin Shoemaker, M., Gustav Smith, J., Biggs, M. L., Bis, J. C., Brody, J. A., Psaty, B. M., Rice, K., Sotoodehnia, N., De Grandi, A., Fuchsberger, C., Pattaro, C., Pramstaller, P. P., Ford, I., Wouter Jukema, J., Macfarlane, P. W., Trompet, S., Dörr, M., Felix, S. B., Völker, U., Weiss, S., Havulinna, A. S., Jula, A., Sääksjärvi, K., Salomaa, V., Guo, X., Heckbert, S. R., Lin, H. J., Rotter, J. I., Taylor, K. D., Yao, J., De Mutsert, R., Maan, A. C., Mook-kanamori, D. O., Noordam, R., Cucca, F., Ding, J., Lakatta, E. G., Qian, Y., Tarasov, K. V., Levy, D., Lin, H., Newton-cheh, C. H., Lunetta, K. L., Murray, A. D., Porteous, D. J., Smith, B. H., Stricker, B. H., Uitterlinden, A., Van Den Berg, M. E., Haessler, J., Jackson, R. D., Kooperberg, C., Peters, U., Reiner, A. P., Whitsel, E. A., Alonso, A., Arking, D. E., Boerwinkle, E., Ehret, G. B., Soliman, E. Z., Avery, C. L., Gogarten, S. M., Kerr, K. F., Laurie, C. C., Seyerle, A. A., Stilp, A., Assa, S., Abdullah Said, M., Yldau Van Der Ende, M., Lambiase, P. D., Orini, M., Ramirez, J., Van Duijvenboden, S., Arnar, D. O., Gudbjartsson, D. F., Holm, H., Sulem, P., Thorleifsson, G., Thorolfsdottir, R. B., Thorsteinsdottir, U., Benjamin, E. J., Tinker, A., Stefansson, K., Ellinor, P. T., Jamshidi, Y., Lubitz, S. A. & Munroe, P. B., 21 May 2020, In: Nature Communications. 11, 1, 12 p., 2542.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • loci
  • Genome-Wide Association Study
  • Genes
  • intervals
  • genes
  2 Citations (Scopus)

  32 Downloads (Pure)

• Mosaic structural variation in children with developmental disorders

  King, D. A., Jones, W. D., Crow, Y. J., Dominiczak, A. F., Foster, N. A., Gaunt, T. R., Harris, J., Hellens, S. W., Homfray, T., Innes, J., Jones, E. A., Joss, S., Kulkarni, A., Mansour, S., Morris, A. D., Parker, M. J., Porteous, D. J., Shihab, H. A., Smith, B. H., Tatton-Brown, K. & 9 others, Tolmie, J. L., Trzaskowski, M., Vasudevan, P. C., Wakeling, E., Wright, M., Plomin, R., Timpson, N. J., Hurles, M. E. & Deciphering Developmental Disorders (DDD) Study, 15 May 2015, In: Human Molecular Genetics. 24, 10, p. 2733-2745 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Mosaicism
  • Child
  • Chimerism
  • Loss of Heterozygosity
  • Genetic Testing
  32 Citations (Scopus)

  14 Downloads (Pure)

• Meta-analysis of exome array data identifies six novel genetic loci for lung function

  Understanding Society Scientific Group, Jackson, V. E., Latourelle, J. C., Wain, L. V., Smith, A. V., Grove, M. L., Bartz, T. M., Obeidat, M., Province, M. A., Gao, W., Qaiser, B., Porteous, D. J., Cassano, P. A., Ahluwalia, T. S., Grarup, N., Li, J., Altmaier, E., Marten, J., Harris, S. E., Manichaikul, A. & 33 others, Pottinger, T. D., Li-Gao, R., Lind-Thomsen, A., Mahajan, A., Lahousse, L., Imboden, M., Teumer, A., Prins, B., Lyytikäinen, L-P., Eiriksdottir, G., Franceschini, N., Sitlani, C. M., Brody, J. A., Bossé, Y., Timens, W., Kraja, A., Loukola, A., Tang, W., Liu, Y., Bork-Jensen, J., Justesen, J. M., Linneberg, A., Lange, L. A., Rawal, R., Karrasch, S., Huffman, J. E., Smith, B. H., Davies, G., Burkart, K. M., Mychaleckyj, J. C., Morris, A. P., Tobin, M. D. & London, S. J., 7 Aug 2018, In: Wellcome Open Research. 3, 28 p., 4.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Exome
  • Genetic Loci
  • Pulmonary diseases
  • Single Nucleotide Polymorphism
  • Meta-Analysis
  7 Citations (Scopus)

  161 Downloads (Pure)

• Major depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass index

  Clarke, T. K., Hall, L. S., Fernandez-Pujals, A. M., MacIntyre, D. J., Thomson, P., Hayward, C., Smith, B. H., Padmanabhan, S., Hocking, L. J., Deary, I. J., Porteous, D. J. & McIntosh, A. M., 30 Jun 2015, In: Translational Psychiatry. 5, 6, p. 1-6 6 p., e592.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Major Depressive Disorder
  • Body Mass Index
  • Obesity
  • Psychology
  • Neuroticism
  16 Citations (Scopus)

  173 Downloads (Pure)

• Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

  Wessel, J., Chu, A. Y., Willems, S. M., Wang, S., Yaghootkar, H., Brody, J. A., Dauriz, M., Hivert, M-F., Raghavan, S., Lipovich, L., Hidalgo, B., Fox, K., Huffman, J. E., An, P., Lu, Y., Rasmussen-Torvik, L. J., Grarup, N., Ehm, M. G., Li, L., Baldridge, A. S. & 31 others, Stančáková, A., Abrol, R., Besse, C., Boland, A., Bork-Jensen, J., Fornage, M., Freitag, D. F., Garcia, M. E., Guo, X., Hara, K., Isaacs, A., Jakobsdottir, J., Lange, L. A., Layton, J. C., Li, M., Hua Zhao, J., Meidtner, K., Morrison, A. C., Nalls, M. A., Peters, M. J., Sabater-Lleal, M., Schurmann, C., Silveira, A., Smith, A. V., Southam, L., Stoiber, M. H., Strawbridge, R. J., Taylor, K. D., Varga, T. V., Smith, B. H. & EPIC-InterAct Consortium, 29 Jan 2015, In: Nature Communications. 6, 16 p., 5897.

  Research output: Contribution to journal › Article › peer-review

  • fasting
  • Exome
  • glucose
  • Medical problems
  • insulin
  111 Citations (Scopus)

• Lessons from Mackenzie that still resonate

  Van Hecke, O., Smith, B. H. & Sullivan, F. M., Mar 2013, In: British Journal of General Practice. 63, 608, p. 158-159 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • General Practitioners
  • Primary Health Care
  • Epidemiology
  • Medicine
  • Research Personnel

• Large-scale discovery of novel genetic causes of developmental disorders

  Deciphering Developmental Disorders (DDD) Study, 12 Mar 2015, In: Nature. 519, 7542, p. 223-228 6 p.

  Research output: Contribution to journal › Letter › peer-review

  • Inborn Genetic Diseases
  • Child
  • Exome
  • Genes
  • Missense Mutation
  504 Citations (Scopus)

• Incidence of iatrogenic opioid dependence or abuse in patients with pain who were exposed to opioid analgesic therapy: a systematic review and meta-analysis

  Higgins, C., Smith, B. & Matthews, K., Jun 2018, In: British Journal of Anaesthesia. 120, 6, p. 1335-1344 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Opioid-Related Disorders
  • Opioid Analgesics
  • Meta-Analysis
  • Systematic Reviews
  • Pain
  33 Citations (Scopus)

  175 Downloads (Pure)

• Impact of sex and age on respiratory support and length of hospital stay among 1792 patients with COVID-19 in Wuhan, China

  Zheng, H., Tan, J., Zhang, X., Luo, A., Wang, L., Zhu, W., Hebert, H. L., Meng, W., Smith, B. H., Colvin, L. A. & Hu, J., 1 Oct 2020, In: British Journal of Anaesthesia. 125, 4, p. E378-E380 3 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Citation (Scopus)

• Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

  Morris, R. W., Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Åsvold, B. O., Elvestad Gabrielsen, M., Campbell, A., Marioni, R., Kumari, M., Korhonen, T., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. V. S., Treur, J. L., Willemsen, G. & 42 others, Dale, C., Wannamethee, S. G., Lahti, J., Palotie, A., Räikkönen, K., McConnachie, A., Padmanabhan, S., Wong, A., Dalgård, C., Paternoster, L., Ben-Shlomo, Y., Tyrrell, J., Horwood, J., Fergusson, D. M., Kennedy, M. A., Nohr, E. A., Christiansen, L., Kyvik, K. O., Kuh, D., Watt, G., Eriksson, J. G., Whincup, P. H., Vink, J. M., Boomsma, D. I., Davey Smith, G., Lawlor, D., Linneberg, A., Ford, I., Jukema, J. W., Power, C., Hyppönen, E., Jarvelin, M-R., Preisig, M., Borodulin, K., Kaprio, J., Kivimaki, M., Smith, B. H., Hayward, C., Romundstad, P. R., Sørensen, T. I. A., Munafò, M. R. & Sattar, N., 11 Aug 2015, In: BMJ Open. 5, 8, 12 p., e008808.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Mendelian Randomization Analysis
  • Waist Circumference
  • Tobacco
  • Smokers
  • Meta-Analysis
  27 Citations (Scopus)

  118 Downloads (Pure)

• Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain

  Suri, P., Palmer, M. R., Tsepilov, Y. A., Freidin, M. B., Boer, C. G., Yau, M. S., Evans, D. S., Gelemanovic, A., Bartz, T. M., Nethander, M., Arbeeva, L., Karssen, L., Neogi, T., Campbell, A., Mellstrom, D., Ohlsson, C., Marshall, L. M., Orwoll, E., Uitterlinden, A., Rotter, J. I. & 17 others, Lauc, G., Psaty, B. M., Karlsson, M. K., Lane, N. E., Jarvik, G. P., Polasek, O., Hochberg, M., Jordan, J. M., Van Meurs, J. B. J., Jackson, R., Nielson, C. M., Mitchell, B. D., Smith, B. H., Hayward, C., Smith, N. L., Aulchenko, Y. S. & Williams, F. M. K., 27 Sep 2018, In: PLoS Genetics. 14, 9, p. 1-23 23 p., e1007601.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • back (body region)
  • meta-analysis
  • ancestry
  • pain
  • Back Pain
  20 Citations (Scopus)

  142 Downloads (Pure)

• Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

  Arnau-Soler, A., Adams, M. J., Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Hayward, C. & Thomson, P. A., 20 Dec 2018, In: PLoS ONE. 13, 12, e0209160.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • mental depression
  • Neuroticism
  • Proxy
  • Major Depressive Disorder
  • Genes
  1 Citation (Scopus)

  161 Downloads (Pure)

• Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP

  Wigmore, E. M., Hafferty, J. D., Hall, L. S., Howard, D. M., Clarke, T-K., Fabbri, C., Lewis, C. M., Uher, R., Navrady, L., Adams, M. J., Zeng, Y., Campbell, A., Gibson, J., Thomson, P. A., Hayward, C., Smith, B., Hocking, L. J., Padmanabhan, S., Deary, I. J., Porteous, D. J. & 4 others, Mors, O., Mattheisen, M., Nicodemus, K. K. & McIntosh, A. M., Apr 2020, In: Pharmacogenomics Journal. 20, p. 329-341 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Genome-Wide Association Study
  • Antidepressive Agents
  • Health Services
  • Prescriptions
  • Meta-Analysis
  14 Citations (Scopus)

  160 Downloads (Pure)

• Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region

  Peters, M. J., Broer, L., Willemen, H. L. D. M., Eiriksdottir, G., Hocking, L. J., Holliday, K. L., Horan, M. A., Meulenbelt, I., Neogi, T., Popham, M., Schmidt, C. O., Soni, A., Valdes, A. M., Amin, N., Dennison, E. M., Eijkelkamp, N., Harris, T. B., Hart, D. J., Hofman, A., Huygen, F. J. P. M. & 32 others, Jameson, K. A., Jones, G. T., Launer, L. J., Kerkhof, H. J. M., De Kruijf, M., McBeth, J., Kloppenburg, M., Ollier, W. E., Oostra, B., Payton, A., Rivadeneira, F., Smith, B. H., Smith, A. V., Stolk, L., Teumer, A., Thomson, W., Uitterlinden, A. G., Wang, K., Van Wingerden, S. H., Arden, N. K., Cooper, C., Felson, D., Gudnason, V., Macfarlane, G. J., Pendleton, N., Slagboom, P. E., Spector, T. D., Völzke, H., Kavelaars, A., Van Duijn, C. M., Williams, F. M. K. & Van Meurs, J. B. J., Mar 2013, In: Annals of the Rheumatic Diseases. 72, 3, p. 427-436 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Chronic Pain
  • Genes
  • Meta-Analysis
  • Chaperonins
  68 Citations (Scopus)

• Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility

  GenoMEL Consortium, Q-MEGA and QTWIN Investigators, ATHENS Melanoma Study Group, 23andMe, The SDH Study Group, IBD Investigators, Essen-Heidelberg Investigators, AMFS Investigators, MelaNostrum Consortium, Landi, M. T., Bishop, D. T., MacGregor, S., Machiela, M. J., Stratigos, A. J., Ghiorzo, P., Brossard, M., Calista, D., Choi, J., Fargnoli, M. C., Zhang, T. & 45 others, Rodolfo, M., Trower, A. J., Menin, C., Martinez, J., Hadjisavvas, A., Song, L., Stefanaki, I., Scolyer, R., Yang, R., Goldstein, A. M., Potrony, M., Kypreou, K. P., Pastorino, L., Queirolo, P., Pellegrini, C., Cattaneo, L., Zawistowski, M., Gimenez-Xavier, P., Rodriguez, A., Elefanti, L., Manoukian, S., Rivoltini, L., Smith, B. H., Loizidou, M. A., Del Regno, L., Massi, D., Mandala, M., Khosrotehrani, K., Akslen, L. A., Amos, C. I., Andresen, P. A., Avril, M-F., Azizi, E., Soyer, H. P., Bataille, V., Dalmasso, B., Bowdler, L. M., Burdon, K. P., Chen, W. V., Codd, V., Craig, J. E., Harris, J., Shi, J., Iles, M. M. & Law, M. H., May 2020, In: Nature Genetics. 52, 5, p. 494-504 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Genome-Wide Association Study
  • Melanoma
  • Meta-Analysis
  • Phenotype
  • Skin
  4 Citations (Scopus)

  452 Downloads (Pure)

• Genetic correlations between pain phenotypes and depression and neuroticism

  Meng, W., Adams, M. J., Reel, P., Rajendrakumar, A., Huang, Y., Deary, I. J., Palmer, C. N. A., McIntosh, A. M. & Smith, B. H., Mar 2020, In: European Journal of Human Genetics. 28, p. 358-366 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Neuroticism
  • Depression
  • Phenotype
  • Pain
  • Linkage Disequilibrium
  3 Citations (Scopus)

  96 Downloads (Pure)

• Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism

  Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Clarke, T-K., Zeng, Y., Navrady, L., Xia, C., Haley, C. S., Campbell, A., Navarro, P., Amador, C., Adams, M. J., Howard, D. M., Soler, A., Hayward, C., Thomson, P. A., Smith, B., Padmanabhan, S., Hocking, L. J., Hall, L. S., Porteous, D. J., Deary, I. J. & 1 others, McIntosh, A. M., 14 Feb 2018, In: Wellcome Open Research. 3, p. 1-10 10 p., 11.

  Research output: Contribution to journal › Article › peer-review

  File

  • Neuroticism
  • Major Depressive Disorder
  • Depression
  • Genes
  • Population Biological Variation
  10 Citations (Scopus)

  171 Downloads (Pure)

• Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

  23andMe Research Team, Lee, J. J., Wedow, R., Okbay, A., Kong, E., Maghzian, O., Zacher, M., Nguyen-Viet, T. A., Bowers, P., Sidorenko, J., Karlsson Linnér, R., Fontana, M. A., Kundu, T., Lee, C., Li, H., Li, R., Royer, R., Timshel, P. N., Walters, R. K., Willoughby, E. A. & 58 others, Yengo, L., Alver, M., Bao, Y., Clark, D. W., Day, F. R., Furlotte, N. A., Joshi, P. K., Kemper, K. E., Kleinman, A., Langenberg, C., Mägi, R., Trampush, J. W., Verma, S. S., Wu, Y., Lam, M., Zhao, J. H., Zheng, Z., Boardman, J. D., Campbell, H., Freese, J., Harris, K. M., Hayward, C., Herd, P., Kumari, M., Lencz, T., Luan, J., Malhotra, A. K., Metspalu, A., Milani, L., Ong, K. K., Smith, B. H., Perry, J. R. B., Porteous, D. J., Ritchie, M. D., Smart, M. C., Tung, J. Y., Wareham, N. J., Wilson, J. F., Beauchamp, J. P., Conley, D., Esko, T., Lehrer, S. F., Magnusson, P. K. E., Oskarsson, S., Pers, T. H., Robinson, M. R., Thom, K., Watson, C., Chabris, C. F., Meyer, M. N., Laibson, D., Yang, J., Johannesson, M., Koellinger, P. D., Turley, P., Visscher, P. M., Benjamin, D. J. & Cesarini, D., 23 Jul 2018, In: Nature Genetics. 50, 8, p. 1112-1121 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Genetic Association Studies
  • Genome-Wide Association Study
  • Single Nucleotide Polymorphism
  • Genome
  • Neurons
  366 Citations (Scopus)

  544 Downloads (Pure)

• Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

  van Leeuwen, E. M., Huffman, J. E., Bis, J. C., Isaacs, A., Mulder, M., Sabo, A., Smith, A. V., Demissie, S., Manichaikul, A., Brody, J. A., Feitosa, M. F., Duan, Q., Schraut, K. E., Navarro, P., van Vliet-Ostaptchouk, J. V., Zhu, G., Mbarek, H., Trompet, S., Verweij, N., Lyytikäinen, L-P. & 31 others, Deelen, J., Nolte, I. M., van der Laan, S. W., Davies, G., Vermeij-Verdoold, A. J., van Oosterhout, A. A., Vergeer-Drop, J. M., Arking, D. E., Trochet, H., Medina-Gomez, C., Rivadeneira, F., Uitterlinden, A. G., Dehghan, A., Franco, O. H., Sijbrands, E. J. G., Hofman, A., White, C. C., Mychaleckyj, J. C., Peloso, G. M., Swertz, M. A., Willemsen, G., de Geus, E. J. C., Milaneschi, Y., Penninx, B. W., Ford, I., Buckley, B. M., de Craen, A. J., Starr, J. M., Deary, I. J., Smith, B. H. & Generation Scotland, 2015, In: NPJ Aging and Mechanisms of Disease. 1, p. 1-9 9 p., 15011.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cholesterol Ester Transfer Proteins
  • Meta-Analysis
  • Genome
  • Particle Size
  • Longevity
  3 Citations (Scopus)

  135 Downloads (Pure)

• Factors associated with unscheduled care use by cancer decedents: a systematic review with narrative synthesis

  Mills, S. E. E., Geneen, L. J., Buchanan, D., Guthrie, B. & Smith, B. H., 13 Oct 2020, In: BMJ Supportive and Palliative Care. 21 p., 002410.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Systematic Reviews
  • Neoplasms
  • Palliative Care
  • Databases
  • Policy Making
  1 Citation (Scopus)

  129 Downloads (Pure)

• Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

  Prins, B. P., Mead, T. J., Brody, J. A., Sveinbjornsson, G., Ntalla, I., Bihlmeyer, N. A., van den Berg, M., Bork-Jensen, J., Cappellani, S., Van Duijvenboden, S., Klena, N. T., Gabriel, G. C., Liu, X., Gulec, C., Grarup, N., Haessler, J., Hall, L. M., Iorio, A., Isaacs, A., Li-Gao, R. & 93 others, Lin, H., Liu, C-T., Lyytikäinen, L-P., Marten, J., Mei, H., Müller-Nurasyid, M., Orini, M., Padmanabhan, S., Radmanesh, F., Ramirez, J., Robino, A., Schwartz, M., van Setten, J., Smith, A. V., Verweij, N., Warren, H. R., Weiss, S., Alonso, A., Arnar, D. O., Bots, M. L., de Boer, R. A., Dominiczak, A. F., Eijgelsheim, M., Ellinor, P. T., Guo, X., Felix, S. B., Harris, T. B., Hayward, C., Heckbert, S. R., Huang, P. L., Jukema, J. W., Kähönen, M., Kors, J. A., Lambiase, P. D., Launer, L. J., Li, M., Linneberg, A., Nelson, C. P., Pedersen, O., Perez, M., Peters, A., Polasek, O., Psaty, B. M., Raitakari, O. T., Rice, K., Rotter, J. I., Sinner, M. F., Soliman, E. Z., Spector, T. D., Strauch, K., Thorsteinsdottir, U., Tinker, A., Trompet, S., Uitterlinden, A. G., Vaartjes, I., van der Meer, P., Völker, U., Völzke, H., Waldenberger, M., Wilson, J. G., Xie, Z., Asselbergs, F. W., Dörr, M., van Duijn, C. M., Gasparini, P., Gudbjartsson, D. F., Gudnason, V., Hansen, T., Kääb, S., Kanters, J. K., Kooperberg, C., Lehtimäki, T., Lin, H. J., Lubitz, S. A., Mook-Kanamori, D. O., Conti, F. J., Newton-Cheh, C., Rosand, J., Rudan, I., Samani, N. J., Sinagra, G., Smith, B., Holm, H., Stricker, B. H. C., Ulivi, S., Sotoodehnia, N., Apte, S. S., van der Harst, P., Stefansson, K., Munroe, P. B., Arking, D. E., Lo, C. W. & Jamshidi, Y., 17 Jul 2018, In: Genome Biology. 19, p. 1-17 17 p., 87.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Exome
  • Connexin 43
  • meta-analysis
  • Gap Junctions
  • Sudden Cardiac Death
  15 Citations (Scopus)

  156 Downloads (Pure)

• Examination of the clinical factors associated with attendance at emergency departments for chronic pain management and the cost of treatment relative to that of other significant medical conditions

  Higgins, C., Smith, B. H. & Colvin, L., 30 Sep 2020, In: Pain.

  Research output: Contribution to journal › Article › peer-review

  • Pain Management
  • Chronic Pain
  • Health Care Costs
  • Hospital Emergency Service
  • Musculoskeletal Pain

• Erratum to: Copy number variation in the human Y chromosome in the UK population

  Wei, W., Fitzgerald, T. W., Ayub, Q., Massaia, A., Smith, B. H., Dominiczak, A. F., Morris, A. D., Porteous, D. J., Hurles, M. E., Tyler-Smith, C. & Xue, Y., Jul 2015, In: Human Genetics. 134, 7, p. 801 1 p.

  Research output: Contribution to journal › Article › peer-review