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Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population
Clarke, T-K., Adams, M. J., Howard, D. M., Xia, C., Davies, G., Hayward, C., Campbell, A., Padmanabhan, S., Smith, B., Murray, A., Porteous, D., Deary, I. J. & McIntosh, A. M., 25 Nov 2019, In: Molecular Psychiatry. 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)70 Downloads (Pure) -
Genetic correlations between pain phenotypes and depression and neuroticism
Meng, W., Adams, M. J., Reel, P., Rajendrakumar, A., Huang, Y., Deary, I. J., Palmer, C. N. A., McIntosh, A. M. & Smith, B. H., Mar 2020, In: European Journal of Human Genetics. 28, p. 358-366 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)101 Downloads (Pure) -
Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations
Understanding Society Scientific Group, Sakornsakolpat, P., Prokopenko, D., Lamontagne, M., Reeve, N. F., Guyatt, A. L., Jackson, V. E., Shrine, N., Qiao, D., Bartz, T. M., Kim, D. K., Lee, M. K., Latourelle, J. C., Li, X., Morrow, J. D., Obeidat, M., Wyss, A. B., Bakke, P., Barr, R. G., Beaty, T. H. & 35 others, , 1 Mar 2019, In: Nature Genetics. 51, 3, p. 494-505 12 p.Research output: Contribution to journal › Article › peer-review
51 Citations (Scopus) -
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
23andMe Research Team, Karlsson Linnér, R., Biroli, P., Kong, E., Meddens, S. F. W., Wedow, R., Fontana, M. A., Lebreton, M., Tino, S. P., Abdellaoui, A., Hammerschlag, A. R., Nivard, M. G., Okbay, A., Rietveld, C. A., Timshel, P. N., Trzaskowski, M., Vlaming, R. D., Zünd, C. L., Bao, Y., Buzdugan, L. & 22 others, , 2019, In: Nature Genetics. 51, 2, p. 245-257 13 p.Research output: Contribution to journal › Article › peer-review
82 Citations (Scopus) -
Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility
GenoMEL Consortium, Q-MEGA and QTWIN Investigators, ATHENS Melanoma Study Group, 23andMe, The SDH Study Group, IBD Investigators, Essen-Heidelberg Investigators, AMFS Investigators, MelaNostrum Consortium, Landi, M. T., Bishop, D. T., MacGregor, S., Machiela, M. J., Stratigos, A. J., Ghiorzo, P., Brossard, M., Calista, D., Choi, J., Fargnoli, M. C., Zhang, T. & 45 others, , May 2020, In: Nature Genetics. 52, 5, p. 494-504 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)544 Downloads (Pure) -
Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region
Peters, M. J., Broer, L., Willemen, H. L. D. M., Eiriksdottir, G., Hocking, L. J., Holliday, K. L., Horan, M. A., Meulenbelt, I., Neogi, T., Popham, M., Schmidt, C. O., Soni, A., Valdes, A. M., Amin, N., Dennison, E. M., Eijkelkamp, N., Harris, T. B., Hart, D. J., Hofman, A., Huygen, F. J. P. M. & 32 others, , Mar 2013, In: Annals of the Rheumatic Diseases. 72, 3, p. 427-436 10 p.Research output: Contribution to journal › Article › peer-review
68 Citations (Scopus) -
Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP
Wigmore, E. M., Hafferty, J. D., Hall, L. S., Howard, D. M., Clarke, T-K., Fabbri, C., Lewis, C. M., Uher, R., Navrady, L., Adams, M. J., Zeng, Y., Campbell, A., Gibson, J., Thomson, P. A., Hayward, C., Smith, B., Hocking, L. J., Padmanabhan, S., Deary, I. J., Porteous, D. J. & 4 others, , Apr 2020, In: Pharmacogenomics Journal. 20, p. 329-341 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)165 Downloads (Pure) -
Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank
Meng, W., Adams, M. J., Palmer, C. N. A., 23andMe Research Team, Shi, J., Auton, A., Ryan, K. A., Jordan, J. M., Mitchell, B. D., Jackson, R. D., Yau, M. S., McIntosh, A. M. & Smith, B. H., 28 Aug 2019, In: Communications Biology. 2, p. 1-8 8 p., 321.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)125 Downloads (Pure) -
Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium
Morris, R. W., Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Åsvold, B. O., Elvestad Gabrielsen, M., Campbell, A., Marioni, R., Kumari, M., Korhonen, T., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. V. S., Treur, J. L., Willemsen, G. & 42 others, , 11 Aug 2015, In: BMJ Open. 5, 8, 12 p., e008808.Research output: Contribution to journal › Article › peer-review
Open AccessFile28 Citations (Scopus)122 Downloads (Pure) -
Implementation of Patient-Reported Outcomes (PROMs) from specialist pain clinics in England and Wales: experience from a nationwide study
Price, C. M., C. de C. Williams, A., Smith, B. H. & Bottle, A., 1 Aug 2019, In: European Journal of Pain. 23, 7, p. 1368-1377 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)30 Downloads (Pure) -
Insulin resistance: Genetic associations with depression and cognition in population based cohorts
Frangou, S., Shirali, M., Adams, M. J., Howard, D. M., Gibson, J., Hall, L. S., Smith, B. H., Padmanabhan, S., Murray, A. D., Porteous, D. J., Haley, C. S., Deary, I. J., Clarke, T-K. & McIntosh, A. M., Jun 2019, In: Experimental Neurology. 316, p. 20-26 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)126 Downloads (Pure) -
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility
Wessel, J., Chu, A. Y., Willems, S. M., Wang, S., Yaghootkar, H., Brody, J. A., Dauriz, M., Hivert, M-F., Raghavan, S., Lipovich, L., Hidalgo, B., Fox, K., Huffman, J. E., An, P., Lu, Y., Rasmussen-Torvik, L. J., Grarup, N., Ehm, M. G., Li, L., Baldridge, A. S. & 31 others, , 29 Jan 2015, In: Nature Communications. 6, 16 p., 5897.Research output: Contribution to journal › Article › peer-review
114 Citations (Scopus) -
Low-frequency variation in TP53 has large effects on head circumference and intracranial volume
UK10K Consortium, 21 Jan 2019, In: Nature Communications. 10, 1, 357.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)113 Downloads (Pure) -
Major depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass index
Clarke, T. K., Hall, L. S., Fernandez-Pujals, A. M., MacIntyre, D. J., Thomson, P., Hayward, C., Smith, B. H., Padmanabhan, S., Hocking, L. J., Deary, I. J., Porteous, D. J. & McIntosh, A. M., 30 Jun 2015, In: Translational Psychiatry. 5, 6, p. 1-6 6 p., e592.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)176 Downloads (Pure) -
Mosaic structural variation in children with developmental disorders
King, D. A., Jones, W. D., Crow, Y. J., Dominiczak, A. F., Foster, N. A., Gaunt, T. R., Harris, J., Hellens, S. W., Homfray, T., Innes, J., Jones, E. A., Joss, S., Kulkarni, A., Mansour, S., Morris, A. D., Parker, M. J., Porteous, D. J., Shihab, H. A., Smith, B. H., Tatton-Brown, K. & 9 others, , 15 May 2015, In: Human Molecular Genetics. 24, 10, p. 2733-2745 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile32 Citations (Scopus)21 Downloads (Pure) -
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions
InterAct Consortium, LifeLines Cohort Study, de Vries, P. S., Brown, M. R., Bentley, A. R., Sung, Y. J., Winkler, T. W., Ntalla, I., Schwander, K., Kraja, A. T., Guo, X., Franceschini, N., Cheng, C-Y., Sim, X., Vojinovic, D., Huffman, J. E., Musani, S. K., Li, C., Feitosa, M. F., Richard, M. A. & 34 others, , 1 Jun 2019, In: American Journal of Epidemiology. 188, 6, p. 1033-1054 22 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)198 Downloads (Pure) -
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction
Ntalla, I., Weng, L., Cartwright, J. H., Hall, A. W., Sveinbjornsson, G., Tucker, N. R., Choi, S. H., Chaffin, M. D., Roselli, C., Barnes, M. R., Mifsud, B., Warren, H. R., Hayward, C., Marten, J., Cranley, J. J., Concas, M. P., Gasparini, P., Boutin, T., Kolcic, I., Polasek, O. & 167 others, , 21 May 2020, In: Nature Communications. 11, 1, 12 p., 2542.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)51 Downloads (Pure) -
Neuropathic pain: a pathway for care developed by the British Pain Society
Smith, B. H., Lee, J., Price, C. & Baranowski, A. P., Jul 2013, In: British Journal of Anaesthesia. 111, 1, p. 73-79 7 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
Neuropathic pain in the community: more under-treated than refractory?
Torrance, N., Ferguson, J. A., Afolabi, E., Bennett, M. I., Serpell, M. G., Dunn, K. M. & Smith, B. H., May 2013, In: Pain. 154, 5, p. 690–699 10 p.Research output: Contribution to journal › Article › peer-review
96 Citations (Scopus) -
Neuropathic pain in the community: prevalence, impact and risk factors
Smith, B. H., Hebert, H. L. & Veluchamy, A., 1 Sep 2020, In: Pain. 161, Supplement 1, p. S127-S137 11 p.Research output: Contribution to journal › Article › peer-review
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Neuropathic pain phenotyping by international consensus (NeuroPPIC) for genetic studies: a NeuPSIG systematic review, Delphi survey, and expert panel recommendations
van Hecke, O., Kamerman, P. R., Attal, N., Baron, R., Bjornsdottir, G., Bennett, D. L. H., Bennett, M. I., Bouhassira, D., Diatchenko, L., Freeman, R., Freynhagen, R., Haanpää, M., Jensen, T. S., Raja, S. N., Rice, A. S. C., Seltzer, Z., Thorgeirsson, T. E., Yarnitsky, D. & Smith, B. H., Nov 2015, In: Pain. 156, 11, p. 2337-2353 17 p.Research output: Contribution to journal › Article › peer-review
35 Citations (Scopus) -
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries
Understanding Society Scientific Group, Shrine, N., Guyatt, A. L., Erzurumluoglu, A. M., Jackson, V. E., Hobbs, B. D., Melbourne, C. A., Batini, C., Fawcett, K. A., Song, K., Sakornsakolpat, P., Li, X., Boxall, R., Reeve, N. F., Obeidat, M., Zhao, J. H., Wielscher, M., Weiss, S., Kentistou, K. A., Cook, J. P. & 33 others, , Mar 2019, In: Nature Genetics. 51, 3, p. 481-493 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile54 Citations (Scopus)430 Downloads (Pure) -
PALS: peer support for community dwelling older people with chronic low back pain: a feasibility and acceptability study
Cooper, K., Schofield, P., Smith, B. H. & Klein, S., Mar 2020, In: Physiotherapy (United Kingdom). 106, p. 154-162 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)140 Downloads (Pure) -
Pedigree and genotyping quality analyses of over 10,000 DNA samples from the Generation Scotland: Scottish Family Health Study
Kerr, S. M., Campbell, A., Murphy, L., Hayward, C., Jackson, C., Wain, L. V., Tobin, M. D., Dominiczak, A., Morris, A., Smith, B. H. & Porteous, D. J., 22 Mar 2013, In: BMC Medical Genetics. 14, 38.Research output: Contribution to journal › Article › peer-review
32 Citations (Scopus) -
Pharmacist-led management of chronic pain in primary care: results from a randomised controlled exploratory trial
Bruhn, H., Bond, C. M., Elliott, A. M., Hannaford, P. C., Lee, A. J., McNamee, P., Smith, B. H., Watson, M. C., Holland, R. & Wright, D., 2013, In: BMJ Open. 3, 4, e002361.Research output: Contribution to journal › Article › peer-review
52 Citations (Scopus) -
Pharmacist-led management of chronic pain in primary care: costs and benefits in a pilot randomised controlled trial
Neilson, A. R., Bruhn, H., Bond, C. M., Elliott, A. M., Smith, B. H., Hannaford, P. C., Holland, R., Lee, A. J., Watson, M., Wright, D. & McNamee, P., 1 Apr 2015, In: BMJ Open. 5, 4, 11 p., e006874.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis
Finnerup, N. B., Attal, N., Haroutounian, S., McNicol, E., Baron, R., Dworkin, R. H., Gilron, I., Haanpää, M., Hansson, P., Jensen, T. S., Kamerman, P. R., Lund, K., Moore, A., Raja, S. N., Rice, A. S. C., Rowbotham, M., Sena, E., Siddall, P., Smith, B. H. & Wallace, M., Feb 2015, In: Lancet Neurology. 14, 2, p. 162-173 12 p.Research output: Contribution to journal › Article › peer-review
1407 Citations (Scopus) -
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution
T2D-Genes Consortium, The MAGIC Investigators, CHD Exome+ Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, ReproGen Consortium, Justice, A. E., Karaderi, T., Highland, H. M., Young, K. L., Graff, M., Lu, Y., Turcot, V., Auer, P. L., Fine, R. S., Guo, X., Schurmann, C., Lempradl, A. & 40 others, , Mar 2019, In: Nature Genetics. 51, 3, p. 452-469 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)279 Downloads (Pure) -
Sex-and Age-Specific Genetic Analysis of Chronic Back Pain
Freidin, M. B., Tsepilov, Y. A., Stanaway, I. B., Meng, W., Hayward, C., Smith, B. H., Khoury, S., Parisien, M., Bortsov, A., Diatchenko, L., Børte, S., Winsvold, B. S., Brumpton, B. M., Zwart, J-A., Aulchenko, Y. S., Suri, P. & Williams, F. M. K., 5 Oct 2020, In: Pain.Research output: Contribution to journal › Article › peer-review
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Sex-differences in the metabolic health of offspring of parents with diabetes: a record-linkage study
Aldhous, M. C., Reynolds, R. M., Campbell, A., Linksted, P., Lindsay, R. S., Smith, B. H., Seckl, J. R., Porteous, D. J., Norman, J. E. & Generation Scotland, 26 Aug 2015, In: PLoS ONE. 10, 8, 18 p., e0134883.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose
Wu, P., Rybin, D., Bielak, L. F., Feitosa, M. F., Franceschini, N., Li, Y., Lu, Y., Marten, J., Musani, S. K., Noordam, R., Raghavan, S., Rose, L. M., Schwander, K., Smith, A. V., Tajuddin, S. M., Vojinovic, D., Amin, N., Arnett, D. K., Bottinger, E. P., Demirkan, A. & 38 others, , 7 May 2020, In: PLoS ONE. 15, 5, p. 1-17 17 p., e0230815.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)32 Downloads (Pure) -
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels
Tin, A., Marten, J., Halperin Kuhns, V. L., Li, Y., Wuttke, M., Kirsten, H., Sieber, K. B., Qiu, C., Gorski, M., Yu, Z., Giri, A., Sveinbjornsson, G., Li, M., Chu, A. Y., Hoppmann, A., O'Connor, L. J., Prins, B., Nutile, T., Noce, D., Akiyama, M. & 31 others, , Oct 2019, In: Nature Genetics. 51, 10, p. 1459–1474 22 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile32 Citations (Scopus)48 Downloads (Pure) -
The National Pain Audit for specialist pain services in England and Wales 2010–2014
Price, C., de C Williams, A. C., Smith, B. H. & Bottle, A., 1 Aug 2019, In: British Journal of Pain. 13, 3, p. 185-193 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)189 Downloads (Pure) -
Trends in gabapentinoid prescribing, co-prescribing of opioids and benzodiazepines, and associated deaths in Scotland
Torrance, N., Veluchamy, A., Zhou, Y., Fletcher, E., Moir, E., Hebert, H., Donnan, P., Watson, J., Colvin, L. & Smith, B. H., Aug 2020, In: British Journal of Anaesthesia. 125, 2, p. 159-167 9 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Variants associated with HHIP expression have sex-differential effects on lung function
Smith, B. H., 1 Jun 2020, In: Wellcome Open Research. 5, p. 1-14 14 p., 111.Research output: Contribution to journal › Article › peer-review
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World Health Organization essential medicines lists: where are the drugs to treat neuropathic pain?
Kamerman, P. R., Wadley, A. L., Davis, K. D., Hietaharju, A., Jain, P., Kopf, A., Meyer, A-C., Raja, S. N., Rice, A. S. C., Smith, B. H., Treede, R-D. & Wiffen, P. J., May 2015, In: Pain. 156, 5, p. 793-797 5 p.Research output: Contribution to journal › Article › peer-review
25 Citations (Scopus)