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• A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors

  Harrison, J. R., Brand, S., Smith, V., Robinson, D. A., Thompson, S., Smith, A., Davies, K., Mok, N., Torrie, L. S., Collie, I., Hallyburton, I., Norval, S., Simeons, F. R. C., Stojanovski, L., Frearson, J. A., Brenk, R., Wyatt, P. G., Gilbert, I. H. & Read, K. D., 12 Sep 2018, In: Journal of Medicinal Chemistry. 61, 18, p. 8374–8389 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • glycylpeptide N-tetradecanoyltransferase
  • African Trypanosomiasis
  • Crystallography
  • Trypanosoma brucei brucei
  • Central Nervous System Diseases
  20 Citations (Scopus)

  211 Downloads (Pure)

• A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1

  Liu, Y., Freeman, A. D. J., Déclais, A-C. & Lilley, D. M. J., 16 Nov 2018, In: Nucleic Acids Research. 46, 20, p. 11089-11098 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ions
  • DNA
  • Substrate Specificity
  • Enzymes
  • Catalytic Domain
  3 Citations (Scopus)

  118 Downloads (Pure)

• A More Scientific Approach to Applied Economics: Reconstructing Statistical, Analytical Significance, and Correlation Analysis

  Altman, M., 28 Feb 2019, In: SSRN Working Paper Series. 23 p.

  Research output: Contribution to journal › Article

  • statistical significance
  • economics
  • causality
  • persistence
  • literature

• A Morphological identification cell cytotoxicity assay using cytoplasm-localized fluorescent probe (CLFP) to distinguish living and dead cells

  Lai, F., Shen, Z., Wen, H., Chen, J., Zhang, X., Lin, P., Yin, D., Cui, H. & Chen, X., 8 Jan 2017, In: Biochemical and Biophysical Research Communications. 482, 2, p. 257-263 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cytotoxicity
  • Assays
  • Fluorescent Dyes
  • Cytoplasm
  • Cells
  10 Citations (Scopus)

  414 Downloads (Pure)

• A mouse model for functional dissection of TAB1 O-GlcNAcylation

  Authier, F., Muha, V. & van Aalten, D. M. F., 27 Aug 2019, In: Wellcome Open Research. 4, 16 p., 128.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Dissection
  • Carrier Proteins
  • Phosphotransferases
  • Phenotype
  • Medical problems
  19 Downloads (Pure)

• A moving interface finite element formulation for layered structures

  Funari, M. F., Greco, F. & Lonetti, P., 1 Jul 2016, In: Composites Part B: Engineering. 96, p. 325-337 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Debonding
  • Crack propagation
  • Composite materials
  34 Citations (Scopus)

• A moving interface finite element formulation to predict dynamic edge debonding in FRP-strengthened concrete beams in service conditions

  Funari, M. F., Spadea, S., Fabbrocino, F. & Luciano, R., Jun 2020, In: Fibers. 8, 6, p. 1-9 9 p., 42.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Debonding
  • Polymers
  • Fibers
  • Concretes
  • Crack initiation
  5 Citations (Scopus)

  213 Downloads (Pure)

• AMP-activated protein kinase: a cellular energy sensor that comes in twelve flavours

  Ross, F. A., MacKintosh, C. & Hardie, D. G., 24 Mar 2016, In: FEBS Journal. 283, 16, p. 2987-3001 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Flavors
  • AMP-Activated Protein Kinases
  • Protein Isoforms
  • Gene encoding
  • Tumors
  139 Citations (Scopus)

  115 Downloads (Pure)

• AMP-Activated Protein Kinase: Friend or Foe in Cancer

  Vara-ciruelos, D., Dandapani, M. & Hardie, D. G., 4 Mar 2020, In: Annual Review of Cancer Biology. 4, p. 1-16 16 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Neoplasms
  • T-Cell Lymphoma
  • Carcinogenesis
  • Protein Kinase Inhibitors
  3 Citations (Scopus)

  43 Downloads (Pure)

• AMP-Activated Protein Kinase: Do We Need Activators or Inhibitors to Treat or Prevent Cancer?

  Russell, F. M. & Hardie, D. G., 27 Dec 2020, In: International Journal of Molecular Sciences. 22, 1, 30 p., 186.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • adenosine monophosphate
  • AMP-Activated Protein Kinases
  • inhibitors
  • cancer
  • Proteins
  57 Downloads (Pure)

• AMP-Activated Protein Kinase: An Ubiquitous Signaling Pathway With Key Roles in the Cardiovascular System

  Salt, I. P. & Hardie, D. G., 26 May 2017, In: Circulation Research. 120, 11, p. 1825-1841 17 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Cardiovascular System
  • Homeostasis
  • Blood Vessels
  • Anti-Inflammatory Agents
  78 Citations (Scopus)

  131 Downloads (Pure)

• AMP-activated protein kinase (AMPK)α2 plays a role in determining the cellular fate of glucose in insulin-resistant mouse skeletal muscle

  Lee-Young, R. S., Bonner, J. S., Mayes, W. H., Iwueke, I., Barrick, B. A., Hasenour, C. M., Kang, L. & Wasserman, D. H., Mar 2013, In: Diabetologia. 56, 3, p. 608-617 10 p.

  Research output: Contribution to journal › Article › peer-review

  • AMP-Activated Protein Kinases
  • Skeletal Muscle
  • Insulin
  • Nitric Oxide Synthase Type II
  • Lipids
  18 Citations (Scopus)

• AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner

  Vlachaki Walker, J. M., Robb, J. L., Cruz, A. M., Malhi, A., Weightman Potter, P. G., Ashford, M. L. J., McCrimmon, R. J., Ellacott, K. L. J. & Beall, C., 21 Apr 2017, In: Diabetes, Obesity & Metabolism. 19, 7, p. 997-1005 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • A 769662
  • AMP-Activated Protein Kinases
  • Astrocytes
  • Adenosine Triphosphate
  • Calcium
  14 Citations (Scopus)

  297 Downloads (Pure)

• AMP-activated protein kinase inhibits K_v1.5 channel currents of pulmonary arterial myocytes in response to hypoxia and inhibition of mitochondrial oxidative phosphorylation

  Moral-Sanz, J., Mahmoud, A. D., Ross, F. A., Eldstrom, J., Fedida, D., Hardie, D. G. & Evans, A. M., 1 Sep 2016, In: Journal of Physiology. 594, 17, p. 4901-4915 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Oxidative Phosphorylation
  • Muscle Cells
  • Hypoxia
  • Lung
  16 Citations (Scopus)

  163 Downloads (Pure)

• AMP-activated protein kinase - not just an energy sensor

  Hardie, D. G. & Lin, S-C., 22 Sep 2017, In: F1000 Research. 6, p. 1-11 11 p., 1724.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Sensors
  • Adenine Nucleotides
  • Adenosine Triphosphate
  • Eukaryota
  47 Citations (Scopus)

  194 Downloads (Pure)

• Amphiphilic oxygenated amorphous carbon-graphite buckypapers with gas sensitivity to polar and non-polar VOCs

  Homaeigohar, S., Sep 2019, In: Nanomaterials. 9, 9, p. 1-14 14 p., 1343.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Amorphous carbon
  • Volatile Organic Compounds
  • Graphite
  • Volatile organic compounds
  • Gases
  3 Citations (Scopus)

  22 Downloads (Pure)

• AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation

  Gowans, G. J., Hawley, S. A., Ross, F. A. & Hardie, D. G., 1 Oct 2013, In: Cell Metabolism. 18, 4, p. 556-566 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Adenosine Monophosphate
  • Phosphorylation
  • Adenosine Diphosphate
  • Adenosine Triphosphate
  276 Citations (Scopus)

  167 Downloads (Pure)

• AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?

  Dandapani, M. & Hardie, D. G., Apr 2013, In: Biochemical Society Transactions. 41, 2, p. 687-693 7 p.

  Research output: Contribution to journal › Article › peer-review
  34 Citations (Scopus)

• AMPK: Sensing Glucose as well as Cellular Energy Status

  Lin, S-C. & Hardie, D., 6 Feb 2018, In: Cell Metabolism. 27, 2, p. 299-313 15 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Adenosine Triphosphatases
  • fructose-1,6-diphosphate
  • Fructose-Bisphosphate Aldolase
  • Glucose
  • Nutrients
  235 Citations (Scopus)

  395 Downloads (Pure)

• AMPK: an energy-sensing pathway with multiple inputs and outputs

  Hardie, D. G., Schaffer, B. E. & Brunet, A., Mar 2016, In: Trends in Cell Biology. 26, 3, p. 190-201 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Adenosine Monophosphate
  • Adenosine Triphosphate
  • Phosphotransferases
  • Phosphorylation
  374 Citations (Scopus)

  359 Downloads (Pure)

• AMPK: mediating the metabolic effects of salicylate-based drugs?

  Steinberg, G. R., Dandapani, M. & Hardie, D. G., Oct 2013, In: Trends in Endocrinology and Metabolism. 24, 10, p. 481-487 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Salicylates
  • AMP-Activated Protein Kinases
  • salicylsalicylic acid
  • Pharmaceutical Preparations
  • Aspirin
  50 Citations (Scopus)

• AMPK: a target for drugs and natural products with effects on both diabetes and cancer

  Hardie, D. G., Jul 2013, In: Diabetes. 62, 7, p. 2164-2172 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Biological Products
  • Metformin
  • Pharmaceutical Preparations
  • Salicylates
  265 Citations (Scopus)

  144 Downloads (Pure)

• AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1-Parkin independent manner

  Seabright, A. P., Fine, N. H. F., Barlow, J. P., Lord, S. O., Musa, I., Gray, A., Bryant, J. A., Banzhaf, M., Lavery, G. G., Hardie, D. G., Hodson, D. J., Philp, A. & Lai, Y-C., 4 May 2020, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 5, p. 6284-6301 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Mitochondrial Degradation
  • Mitochondrial Dynamics
  • Adenosine Monophosphate
  • Protein Kinases
  • Chemical activation
  5 Citations (Scopus)

  82 Downloads (Pure)

• AMPK and the Need to Breathe and Feed: What's the Matter with Oxygen?

  Evans, A. M. & Hardie, D. G., 15 May 2020, In: International Journal of Molecular Sciences. 21, 10, p. 1-28 28 p., 3518.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • adenosine monophosphate
  • AMP-Activated Protein Kinases
  • Oxygen supply
  • Proteins
  • Oxygen
  29 Downloads (Pure)

• AMPK and TOR: the Yin and Yang of cellular nutrient sensing and growth control

  González, A., Hall, M. N., Lin, S-C. & Hardie, G., 3 Mar 2020, In: Cell Metabolism. 31, 3, p. 472-492 21 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Yin-Yang
  • AMP-Activated Protein Kinases
  • Sirolimus
  • Nutrients
  • Growth
  29 Citations (Scopus)

• AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B

  Johanns, M., Lai, Y. C., Hsu, M. F., Jacobs, R., Vertommen, D., Van Sande, J., Dumont, J. E., Woods, A., Carling, D., Hue, L., Viollet, B., Foretz, M. & Rider, M. H., 8 Mar 2016, In: Nature Communications. 7, 10856.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • cyclic AMP
  • Phosphorylation
  • adenosine monophosphate
  • Type 4 Cyclic Nucleotide Phosphodiesterase
  • phosphorylation
  58 Citations (Scopus)

• AMPK as a direct sensor of long-chain fatty acyl–CoA esters

  Hardie, D. G., 27 Jul 2020, In: Nature Metabolism. 2, 9, p. 799-800 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Esters
  • Starvation
  • Ligands
  • Glucose
  5 Citations (Scopus)

  13 Downloads (Pure)

• AMPK Causes Cell Cycle Arrest in LKB1-deficient Cells via Activation of CAMKK2

  Fogarty, S., Ross, F. A., Vara Ciruelos, D., Gray, A., Gowans, G. J. & Hardie, D. G., 1 Aug 2016, In: Molecular Cancer Research. 14, 8, p. 683-695 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Cell Cycle Checkpoints
  • Null Lymphocytes
  • Calcimycin
  • Phosphorylation
  35 Citations (Scopus)

  321 Downloads (Pure)

• AMPK modulates glucose-sensing in insulin-secreting cells by altered phosphotransfer to KATP channels

  Beall, C., Watterson, K. R., McCrimmon, R. J. & Ashford, M. L. J., Jun 2013, In: Journal of Bioenergetics and Biomembranes. 45, 3, p. 229-241 13 p.

  Research output: Contribution to journal › Article › peer-review

  • KATP Channels
  • AMP-Activated Protein Kinases
  • Insulin-Secreting Cells
  • Glucose
  • Adenylate Kinase
  14 Citations (Scopus)

• AMPKα1: a glucose sensor that controls CD8 T-cell memory

  Rolf, J., Zarrouk, M., Finlay, D. K., Foretz, M., Viollet, B. & Cantrell, D. A., Apr 2013, In: European Journal of Immunology. 43, 4, p. 889-896 8 p.

  Research output: Contribution to journal › Article › peer-review
  138 Citations (Scopus)

• Amputation-free survival in 17,353 people at high risk for foot ulceration in diabetes: a national observational study

  Scottish Diabetes Research Network Epidemiology Group, Vadiveloo, T., Jeffcoate, W., Donnan, P. T., Colhoun, H. C., McGurnaghan, S., Wild, S., McCrimmon, R. & Leese, G. P., Dec 2018, In: Diabetologia. 61, 12, p. 2590-2597 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Amputation
  • Ulcer
  • Foot
  • Observational Studies
  • Scotland
  15 Citations (Scopus)

  196 Downloads (Pure)

• A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

  LifeLines Cohort Study, Sung, Y. J., de Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D. & 40 others, Marten, J., Musani, S. K., Kilpeläinen, T. O., Richard, M. A., Aslibekyan, S., Bartz, T. M., Dorajoo, R., Li, C., Liu, Y., Rankinen, T., Smith, A. V., Tajuddin, S. M., Tayo, B. O., Zhao, W., Zhou, Y., Matoba, N., Sofer, T., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Giulianini, F., Goel, A., Harris, S. E., Hartwig, F. P., Connell, J. M., Smith, B. H., Rotter, J. I., Franks, P. W., Rice, K., Elliott, P., Caulfield, M. J., Gauderman, W. J., Munroe, P. B., Rao, D. C. & Morrison, A. C., 1 Aug 2019, In: Human Molecular Genetics. 28, 15, p. 2615-2633 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Arterial Pressure
  • Smoking
  • Genome
  • Blood Pressure
  • Genes
  5 Citations (Scopus)

  70 Downloads (Pure)

• A Multicellular Model of Intestinal Crypt Buckling and Fission

  Almet, A. A., Hughes, B. D., Landman, K. A., Näthke, I. S. & Osborne, J. M., Feb 2018, In: Bulletin of Mathematical Biology. 80, 2, p. 335-359 25 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • intestinal crypts
  • buckling
  • Buckling
  • Organoids
  • Tissue
  3 Citations (Scopus)

  231 Downloads (Pure)

• A Multicenter, Randomized, Placebo-Controlled Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients With Rheumatoid Arthritis: A multicenter, randomized, placebo controlled trial

  Kitas, G. D., Nightingale, P., Armitage, J., Sattar, N., Belch, J. J. F. & Symmons, D. P. M., Sep 2019, In: Arthritis and Rheumatology. 71, 9, p. 1437-1449 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Atorvastatin
  • Primary Prevention
  • Rheumatoid Arthritis
  • Placebos
  • Randomized Controlled Trials
  31 Citations (Scopus)

  44 Downloads (Pure)

• A multi-centre, prospective epidemiological surveillance study considering ophthalmic complications of functional endoscopic sinus surgery

  Burgess, S., Foulds, J., White, P., Foot, B. & Macewen, C., Mar 2020, In: Journal of Laryngology and Otology. 134, 3, p. 228-232 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Epidemiologic Studies
  • Eye
  • Nasolacrimal Duct
  • Muscles
  • Consultants
  1 Citation (Scopus)

  47 Downloads (Pure)

• A multicentre parallel-group randomised trial assessing multiparametric MRI characterisation and image-guided biopsy of prostate in men suspected of having prostate cancer: MULTIPROS study protocol

  Szewczyk-Bieda, M., Wei, C., Coll, K., Gandy, S., Donnan, P., Ragupathy, S. K. A., Singh, P., Wilson, J. & Nabi, G., 21 Nov 2019, In: Trials. 20, p. 1-8 8 p., 638.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Image-Guided Biopsy
  • Prostate
  • Prostatic Neoplasms
  • Biopsy
  • Magnetic Resonance Imaging
  2 Citations (Scopus)

  78 Downloads (Pure)

• A multicentre review of bakery and dental series allergens tested for cheilitis in the UK

  Fatah, S., Horne, H. L., Wilkinson, S. M., Gawkrodger, D. J., English, J. S. C., Green, C. M., Ormerod, A. D., Chowdhury, M. M. U., Cooper, S. M., Stone, N. M., King, C. M. & Johnston, G. A., Jul 2013, In: British Journal of Dermatology. 169, Suppl. 1, p. 132 1 p., CD09.

  Research output: Contribution to journal › Meeting abstract › peer-review

• A Multi-disciplinary Approach to the Archaeological Investigation of a Bedrock-Dominated Shallow-Marine Landscape: An example from the Bay of Firth, Orkney, UK

  Bates, M. R., Nayling, N., Bates, R., Dawson, S., Huws, D. & Wickham-Jones, C., Mar 2013, In: International Journal of Nautical Archaeology. 42, 1, p. 24-43 20 p.

  Research output: Contribution to journal › Article › peer-review

  • Orkney
  • Archaeological Investigation
  • archaeology
  • bedrock
  • Coastal Geomorphology
  22 Citations (Scopus)

• A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13

  Leslie, E. J., Carlson, J. C., Shaffer, J. R., Feingold, E., Wehby, G., Laurie, C. A., Jain, D., Laurie, C. C., Doheny, K. F., McHenry, T., Resick, J., Sanchez, C., Jacobs, J., Emanuele, B., Vieira, A. R., Neiswanger, K., Lidral, A. C., Valencia-Ramirez, L. C., Lopez-Palacio, A. M., Valencia, D. R. & 35 others, Arcos-Burgos, M., Czeizel, A. E., Field, L. L., Padilla, C. D., Cutiongco-de la Paz, E. M. C., Deleyiannis, F., Christensen, K., Munger, R. G., Lie, R. T., Wilcox, A., Romitti, P. A., Castilla, E. E., Mereb, J. C., Poletta, F. A., Orioli, I. M., Carvalho, F. M., Hecht, J. T., Blanton, S. H., Buxó, C. J., Butali, A., Mossey, P. A., Adeyemo, W. L., James, O., Braimah, R. O., Aregbesola, B. S., Eshete, M. A., Abate, F., Koruyucu, M., Seymen, F., Ma, L., de Salamanca, J. E., Weinberg, S. M., Moreno, L., Murray, J. C. & Marazita, M. L., 1 Jul 2016, In: Human Molecular Genetics. 25, 13, p. 2862-2872 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cleft Lip
  • Cleft Palate
  • Genome-Wide Association Study
  • Genes
  • Actin Cytoskeleton
  86 Citations (Scopus)

• A multifaceted approach to identify non-specific enzyme inhibition: Application to Mycobacterium tuberculosis shikimate kinase

  Alturki, M. S., Fuanta, N. R., Jarrard, M. A., Hobrath, J. V., Goodwin, D. C., Rants'o, T. A. & Calderón, A. I., 15 Feb 2018, In: Bioorganic and Medicinal Chemistry Letters. 28, 4, p. 802-808 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • shikimate kinase
  • Enzyme inhibition
  • Assays
  • Mycobacterium tuberculosis
  • Screening
  6 Citations (Scopus)

  165 Downloads (Pure)

• A multimodal approach to cardiovascular risk stratification in patients with type 2 diabetes incorporating retinal, genomic and clinical features

  Fetit, A., Doney, A., Hogg, S., Wang, R., MacGillivray, T., Wardlaw, J. M., Doubal, F. N., McKay, G. J., McKenna, S. & Trucco, E., 5 Mar 2019, In: Scientific Reports. 9, 10 p., 3591.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Single Nucleotide Polymorphism
  • Type 2 Diabetes Mellitus
  • Biomarkers
  • Blood Pressure
  • Risk Assessment
  5 Citations (Scopus)

  139 Downloads (Pure)

• A multiorganism pipeline for antiseizure drug discovery: Identification of chlorothymol as a novel γ-aminobutyric acidergic anticonvulsant

  Jones, A., Barker-Haliski, M., Ilie, A. S., Herd, M. B., Baxendale, S., Holdsworth, C. J., Ashton, J. P., Placzek, M., Jayasekera, B. A. P., Cowie, C. J. A., Lambert, J. J., Trevelyan, A. J., White, H. S., Marson, A. G., Cunliffe, V. T., Sills, G. J. & Morgan, A., Oct 2020, In: Epilepsia. 61, 10, p. 2106-2118 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Drug Discovery
  • Anticonvulsants
  • Seizures
  • Epilepsy
  • Zebrafish
  25 Downloads (Pure)

• A multiscale mathematical model of tumour invasive growth

  Peng, L., Trucu, D., Lin, P., Thompson, A. & Chaplain, M. A. J., Mar 2017, In: Bulletin of Mathematical Biology. 79, 3, p. 389-429 41 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Multiscale Model
  • Tumor
  • tumor
  • Tumors
  • Cancer
  17 Citations (Scopus)

  179 Downloads (Pure)

• A multiscale moving boundary model arising in cancer invasion

  Trucu, D., Lin, P., Chaplain, M. A. J. & Wang, Y., 2013, In: Multiscale Modeling and Simulation: A SIAM Interdisciplinary Journal. 11, 1, p. 309-335 27 p.

  Research output: Contribution to journal › Article › peer-review

  • Invasion
  • Moving Boundary
  • Cancer
  • Cells
  • cancer
  22 Citations (Scopus)

• A multispecialty study of determining the possibility of pregnancy and the documentation of pregnancy status in surgical patients: a cause for concern?

  Ibrahim, I., Ibrahim, B., Yong, G. L., Coats, M., Vujovic, Z. & Wilson, M. S. J., 1 Nov 2018, In: Scottish Medical Journal. 63, 4, p. 108-112 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Documentation
  • Pregnancy
  • Surgical Specialties
  • Neurosurgery
  • Gynecology

• A multispectral endoscope based on spectrally resolved detector arrays

  Luthman, S., Waterhouse, D., Bollepalli, L., Joseph, J. & Bohndiek, S., 28 Jul 2017, Clinical and Preclinical Optical Diagnostics. Brown, J. Q. & van Leeuwen, T. G. (eds.). Society of Photo-optical Instrumentation Engineers, 3 p. 104110A. (Proceedings of SPIE; vol. 10411).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • endoscopes
  • Endoscopy
  • Endoscopes
  • Fluorescence imaging
  • Detectors

• A Multi-task Deep Network for Person Re-identification

  Chen, W., Chen, X., Zhang, J. & Huang, K., 17 Feb 2017, Proceedings of The Thirty-First AAAI Conference on Artificial Intelligence (AAAI-17). Singh, S. & Markovitch, S. (eds.). Palo Alto, CA: AAAI Press, p. 3988-3994 7 p.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  Open Access

  File

  • Experiments
  108 Citations (Scopus)

  116 Downloads (Pure)

• A mutant O-GlcNAcase enriches Drosophila developmental regulators

  Selvan, N., Williamson, R., Mariappa, D., Campbell, D. G., Gourlay, R., Ferenbach, A. T., Aristotelous, T., Hopkins-Navratilova, I., Trost, M. & van Aalten, D. M. F., Aug 2017, In: Nature Chemical Biology. 13, 8, p. 882-887 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • hexosaminidase C
  • O-GlcNAc transferase
  • Drosophila
  • Embryonic Development
  • Proteins
  22 Citations (Scopus)

  199 Downloads (Pure)

• Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease

  Pickett, E. K., Herrmann, A. G., McQueen, J., Abt, K., Dando, O., Tulloch, J., Jain, P., Dunnett, S., Sohrabi, S., Fjeldstad, M. P., Calkin, W., Murison, L., Jackson, R. J., Tzioras, M., Stevenson, A., d'Orange, M., Hooley, M., Davies, C., Colom-Cadena, M., Anton-Fernandez, A. & 10 others, King, D., Oren, I., Rose, J., McKenzie, C. A., Allison, E., Smith, C., Hardt, O., Henstridge, C. M., Hardingham, G. E. & Spires-Jones, T. L., 10 Dec 2019, In: Cell Reports. 29, 11, p. 3592-3604.e5

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Amyloid
  • Alzheimer Disease
  • Amyloid beta-Peptides
  • Phenotype
  • tau Proteins
  24 Citations (Scopus)

  74 Downloads (Pure)

• Amyloid β fibril disruption by oleuropein aglycone: long-time molecular dynamics simulation to gain insight into the mechanism of action of this polyphenol from extra virgin olive oil

  Brogi, S., Sirous, H., Calderone, V. & Chemi, G., 23 Sep 2020, In: Food & Function. 11, 9, p. 8122-8132 11 p.

  Research output: Contribution to journal › Article › peer-review

  • oleuropein aglycone
  • oleuropein
  • extra-virgin olive oil
  • molecular dynamics
  • Olive Oil