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  • 2020
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Author

  • Julian Blow
2020

3.0 tera-basepairs as a fundamental limit for robust DNA replication

Al Mamun, M., Albergante, L., Blow, J. & Newman, T., 22 Apr 2020, In : Physical Biology.

Research output: Contribution to journalArticle

Open Access
File
25 Downloads (Pure)
2019

Defects in the origin licensing checkpoint stresses cells exiting G0

Blow, J. J., 1 Jul 2019, In : Journal of Cell Biology. 218, 7, p. 2080-2081 2 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
76 Downloads (Pure)
2018

Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing

Shoaib, M., Walter, D., Gillespie, P. J., Izard, F., Fahrenkrog, B., Lleres, D., Lerdrup, M., Johansen, J. V., Hansen, K., Julien, E., Blow, J. J. & Sørensen, C. S., 12 Sep 2018, In : Nature Communications. 9, 1, p. 1-11 11 p., 3704.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
115 Downloads (Pure)

Lgr5+ intestinal stem cells reside in an unlicensed G1 phase

Carroll, T., Newton, I., Chen, Y., Blow, J. & Nathke, I., 7 May 2018, In : Journal of Cell Biology. 217, 5, p. 1667-1685 19 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
159 Downloads (Pure)

The Anthelmintic Drug Niclosamide and Its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1

Barini, E., Miccoli, A., Tinarelli, F., Mulholland, K., Kadri, H., Khanim, F., Stojanovski, L., Read, K. D., Burness, K., Blow, J. J., Mehellou, Y. & Muqit, M. M. K., 2 Mar 2018, In : ChemBioChem. 19, 5, p. 425-429 5 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
148 Downloads (Pure)
2017

Reversal of DDK-mediated MCM phosphorylation by Rif1-PP1 regulates replication initiation and replisome stability independently of ATR/Chk1

Alver, R. C., Chadha, G. S., Gillespie, P. J. & Blow, J. J., 7 Mar 2017, In : Cell Reports. 18, 10, p. 2508-2520 13 p.

Research output: Contribution to journalArticle

Open Access
File
36 Citations (Scopus)
160 Downloads (Pure)

The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines

Gardner, N. J., Gillespie, P. J., Carrington, J. T., Shanks, E. J., McElroy, S. P., Haagensen, E. J., Frearson, J. A., Woodland, A. & Blow, J. J., 17 Aug 2017, In : Cell Chemical Biology. 24, 8, p. 981-992.e4 16 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
141 Downloads (Pure)
2016

Cell cycle synchronization in xenopus egg extracts

Gillespie, P. J., Neusiedler, J., Creavin, K., Chadha, G. S. & Blow, J., 2016, Cell cycle oscillators: methods and protocols. Coutts, A. S. & Weston, L. (eds.). New York: Humana Press, p. 101-147 47 p. (Methods in Molecular Biology; vol. 1342).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

5 Citations (Scopus)

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

Galanos, P., Vougas, K., Walter, D., Polyzos, A., Maya-Mendoza, A., Haagensen, E. J., Kokkalis, A., Roumelioti, F-M., Gagos, S., Tzetis, M., Canovas, B., Igea, A., Ahuja, A. K., Zellweger, R., Havaki, S., Kanavakis, E., Kletsas, D., Roninson, I. B., Garbis, S. D., Lopes, M. & 7 others, Nebreda, A., Thanos, D., Blow, J. J., Townsend, P., Sørensen, C. S., Bartek, J. & Gorgoulis, V. G., Jul 2016, In : Nature Cell Biology. 18, 7, p. 777-789 13 p.

Research output: Contribution to journalArticle

Open Access
File
104 Citations (Scopus)
576 Downloads (Pure)

Direct non transcriptional role of NF-Y in DNA replication

Benatti, P., Belluti, S., Miotto, B., Neusiedler, J., Dolfini, D., Drac, M., Basile, V., Schwob, E., Mantovani, R., Blow, J. J. & Imbriano, C., 1 Apr 2016, In : Biochimica et Biophysica Acta. Molecular Cell Research. 1863, 4, p. 673-685 13 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
134 Downloads (Pure)

Inevitability and containment of replication errors for eukaryotic genome lengths spanning Megabase to Gigabase

Al Mamun, M., Albergante, L., Moreno, A., Carrington, J. T., Blow, J. & Newman, T. J., 27 Sep 2016, In : Proceedings of the National Academy of Sciences. 113, 39, p. E5765-E5774 10 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
440 Downloads (Pure)

The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability

Ho, T. L. F., Guilbaud, G., Blow, J. J., Sale, J. E. & Watson, C. J., 26 Apr 2016, In : Cell Reports. 15, 4, p. 724-734 11 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
142 Downloads (Pure)
Open Access
File
11 Citations (Scopus)
281 Downloads (Pure)

Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability

Lachaud, C., Moreno, A., Marchesi, F., Toth, R., Blow, J. J. & Rouse, J., 19 Feb 2016, In : Science. 351, 6275, p. 846-849 4 p.

Research output: Contribution to journalArticle

Open Access
58 Citations (Scopus)

Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells

Moreno, A., Carrington, J. T., Albergante, L., Al Mamun, M., Haagensen, E. J., Komseli, E-S., Gorgoulis, V. G., Newman, T. J. & Blow, J., 27 Sep 2016, In : Proceedings of the National Academy of Sciences. 113, 39, p. E5757-E5764 8 p.

Research output: Contribution to journalArticle

Open Access
File
46 Citations (Scopus)
358 Downloads (Pure)
Open Access
File
3 Citations (Scopus)
172 Downloads (Pure)

Xenopus Mcm10 is a CDK-substrate required for replication fork stability

Chadha, G. S., Gambus, A., Gillespie, P. J. & Blow, J., 2016, In : Cell Cycle. 15, 16, p. 2183-2195 13 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
223 Downloads (Pure)
2015

Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C.elegans Embryos

Sonneville, R., Craig, G., Labib, K., Gartner, A. & Blow, J. J., 21 Jul 2015, In : Cell Reports. 12, 3, p. 405-417 13 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
193 Downloads (Pure)
1 Citation (Scopus)
2014

Buffered Qualitative Stability explains the robustness and evolvability of transcriptional networks

Albergante, L., Blow, J. J. & Newman, T. J., 2 Sep 2014, In : eLife. 3, p. 1-28 28 p., e02863.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
168 Downloads (Pure)
Open Access
27 Citations (Scopus)

The contribution of dormant origins to genome stability: from cell biology to human genetics

Alver, R. C., Chadha, G. S. & Blow, J. J., Jul 2014, In : DNA Repair. 19, p. 182-189 8 p.

Research output: Contribution to journalArticle

Open Access
File
50 Citations (Scopus)
214 Downloads (Pure)

Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1

Poh, W. T., Chadha, G. S., Gillespie, P. J., Kaldis, P. & Blow, J. J., 8 Jan 2014, In : Open Biology. 4, January, 130138.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
134 Downloads (Pure)