Find Research Outputs

Search results

• 2014

  Adrenal suppression with mometasone furoate/formoterol

  Lipworth, B. J., May 2014, In: Chest. 145, 5, p. 1175-1176 2 p.

  Research output: Contribution to journal › Letter › peer-review

• Adverse respiratory effect of acute beta-blocker exposure in asthma: a systematic review and meta-analysis of randomized controlled trials

  Morales, D. R., Jackson, C., Lipworth, B. J., Donnan, P. T. & Guthrie, B., Apr 2014, In: Chest. 145, 4, p. 779-786

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Meta-Analysis
  • Systematic Reviews
  • Randomized Controlled Trials
  • Celiprolol
  58 Citations (Scopus)

• Effects of intravenous and oral β-blockade in persistent asthmatics controlled on inhaled corticosteroids

  Short, P. M., Anderson, W. J., Williamson, P. A. & Lipworth, B. J., Feb 2014, In: Heart (British Cardiac Society). 100, 3, p. 219-223 5 p.

  Research output: Contribution to journal › Article › peer-review

  • esmolol
  • Propranolol
  • Adrenal Cortex Hormones
  • Asthma
  • Cardiovascular Diseases
  15 Citations (Scopus)

• Emerging role of long acting muscarinic antagonists for asthma

  Lipworth, B. J., Jan 2014, In: British Journal of Clinical Pharmacology. 77, 1, p. 55-62 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Muscarinic Antagonists
  • Asthma
  • Adrenal Cortex Hormones
  • Respiratory Hypersensitivity
  • Airway Management
  25 Citations (Scopus)

• Impact of long-acting bronchodilators and exposure to inhaled corticosteroids on mortality in COPD: a real-life retrospective cohort study

  Manoharan, A., Short, P. M., Anderson, W. J. & Lipworth, B. J., Oct 2014, In: Lung. 192, 5, p. 649-652 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Bronchodilator Agents
  • Chronic Obstructive Pulmonary Disease
  • Muscarinic Antagonists
  • Adrenal Cortex Hormones
  • Cohort Studies
  12 Citations (Scopus)

• Influence of β₂-adrenoceptor 16 genotype on propranolol-induced bronchoconstriction in patients with persistent asthma

  Anderson, W. J., Short, P. M., Manoharan, A., Lipworth, J. L. R. & Lipworth, B. J., 2014, In: Annals of Allergy, Asthma & Immunology. 112, 5, p. 475-476 2 p.

  Research output: Contribution to journal › Letter › peer-review
  4 Citations (Scopus)

• Lack of clinically relevant differences between combination therapy and monotherapy in COPD

  Lipworth, B. J., Apr 2014, In: European Respiratory Journal. 43, 4, p. 1204 1 p.

  Research output: Contribution to journal › Article › peer-review

• Proof of concept evaluation of trough airway hyper-responsiveness following regular racemic or levosalbutamol in genotype-stratified steroid-treated persistent asthmatic patients

  Anderson, W. J., Short, P. M., Williamson, P. A., Morrison, A. E., Palmer, C., Tavendale, R. & Lipworth, B. J., 1 Jan 2014, In: Clinical Science. 126, 1, p. 75-83 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Respiratory Hypersensitivity
  • Proof of Concept Study
  • Albuterol
  • Steroids
  • Genotype
  3 Citations (Scopus)

• Reply: pharmacological obfuscation of clinical relevance

  Lipworth, B., Short, P., Anderson, W. & Williamson, P., 1 Feb 2014, In: American Journal of Respiratory and Critical Care Medicine. 189, 3, p. 360-361 2 p.

  Research output: Contribution to journal › Letter › peer-review
  2 Citations (Scopus)

• Safety risks for patients with aspirin-exacerbated respiratory disease after acute exposure to selective nonsteroidal anti-inflammatory drugs and COX-2 inhibitors: meta-analysis of controlled clinical trials

  Morales, D. R., Lipworth, B. J., Guthrie, B., Jackson, C., Donnan, P. T. & Santiago, V. H., Jul 2014, In: Journal of Allergy and Clinical Immunology. 134, 1, p. 40-45.e10 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclooxygenase 2 Inhibitors
  • Controlled Clinical Trials
  • Acute Disease
  • Patient Safety
  • Aspirin
  43 Citations (Scopus)

• Small airway dysfunction is associated with poorer asthma control

  Manoharan, A., Anderson, W. J., Lipworth, J., Ibrahim, I. & Lipworth, B. J., Nov 2014, In: European Respiratory Journal. 44, 5, p. 1353-1355 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  30 Citations (Scopus)

  139 Downloads (Pure)

• Tadalafil in patients with chronic obstructive pulmonary disease: a randomised, double-blind, parallel-group, placebo-controlled trial

  Goudie, A. R., Lipworth, B. J., Hopkinson, P. J., Wei, L. & Struthers, A. D., Apr 2014, In: The Lancet Respiratory Medicine. 2, 4, p. 293-300 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Tadalafil
  • Chronic Obstructive Pulmonary Disease
  • Placebos
  • Dyspepsia
  • Quality of Life
  59 Citations (Scopus)

  174 Downloads (Pure)

• The inverse agonist propranolol confers no corticosteroid-sparing activity in mild-to-moderate persistent asthma

  Anderson, W. J., Short, P. M., Williamson, P. A., Manoharan, A. & Lipworth, B. J., Dec 2014, In: Clinical Science. 127, 11, p. 635-643 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Propranolol
  • Adrenal Cortex Hormones
  • Asthma
  • apaflurane
  • Beclomethasone
  13 Citations (Scopus)

• The potential role of direct and indirect bronchial challenge testing to identify overtreatment of community managed asthma

  Manoharan, A., Lipworth, B., Craig, E. & Jackson, C., Oct 2014, In: Clinical and Experimental Allergy. 44, 10, p. 1240-1245 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Medical Overuse
  • Asthma
  • Methacholine Chloride
  • Mannitol
  • Medical Informatics
  13 Citations (Scopus)

• Unlocking the quiet zone: the small airway asthma phenotype

  Lipworth, B., Manoharan, A. & Anderson, W., 2014, In: The Lancet Respiratory Medicine. 2, 6, p. 497-506 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Phenotype
  • Nebulizers and Vaporizers
  • Lung
  • Adrenal Cortex Hormones
  65 Citations (Scopus)
• 2017

  An algorithm recommendation for the pharmacological management of allergic rhinitis in the UK: a consensus statement from an expert panel

  Lipworth, B., Newton, J., Ram, B., Small, I. & Schwarze, J., 23 Jan 2017, In: NPJ Primary Care Respiratory Medicine. 27, p. 1-8 8 p., 3.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Allergic Rhinitis
  • Consensus
  • Pharmacology
  • Primary Health Care
  • Secondary Care
  7 Citations (Scopus)

  169 Downloads (Pure)

• A pragmatic approach to simplifying inhaler therapy for COPD

  Lipworth, B. & Jabbal, S., Sep 2017, In: The Lancet Respiratory Medicine. 5, 9, p. 679-681 3 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  File
  5 Citations (Scopus)

  122 Downloads (Pure)

• Blood eosinophils: The forgotten man of inhaled steroid dose titration

  Jabbal, S. & Lipworth, B. J., 28 Dec 2017, In: Clinical and Experimental Allergy. 48, p. 93-95 3 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File
  5 Citations (Scopus)

  188 Downloads (Pure)

• Bronchoprotective tolerance with indacaterol is not modified by concomitant tiotropium in persistent asthma

  Jabbal, S., Manoharan, A. & Lipworth, B. J., Oct 2017, In: Clinical and Experimental Allergy. 47, 10, p. 1239-1245 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • indacaterol
  • Tiotropium Bromide
  • Asthma
  • Mannitol
  • Muscarinic Antagonists
  5 Citations (Scopus)

  196 Downloads (Pure)

• Cardiopulmonary interactions with beta-blockers and inhaled therapy in COPD

  Jabbal, S., Anderson, W., Short, P., Morrison, A., Manoharan, A. & Lipworth, B. J., Dec 2017, In: QJM : an International Journal of Medicine. 110, 12, p. 785-792 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Carvedilol
  • Bisoprolol
  • Chronic Obstructive Pulmonary Disease
  • Forced Expiratory Volume
  • Tiotropium Bromide
  3 Citations (Scopus)

  175 Downloads (Pure)

• Debate on long-acting β agonists for asthma: they think it's all over

  Lipworth, B. & Jabbal, S., Mar 2017, In: The Lancet Respiratory Medicine. 5, 3, p. e14-e15 2 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File

  • Asthma
  • Adrenal Cortex Hormones
  • Nebulizers and Vaporizers
  • United States Food and Drug Administration
  • Guidelines
  1 Citation (Scopus)

  220 Downloads (Pure)

• Does size really matter: relationship of particle size to lung deposition and exhaled fraction

  Jabbal, S., Poli, G. & Lipworth, B., Jun 2017, In: Journal of Allergy and Clinical Immunology. 139, 6, p. 2013-2014.e1 3 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File

  • Particle Size
  • Asthma
  • Lung
  13 Citations (Scopus)

  174 Downloads (Pure)

• Drug-device interaction for systemic effects of fluticasone in patients with asthma

  Lipworth, B. J. & Jabbal, S., Aug 2017, In: Annals of Allergy, Asthma & Immunology. 119, 2, p. 194 1 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Citation (Scopus)

• Erratum to: Comparative lung bioavailability of fluticasone/salmeterol via a breath-actuated spacer and conventional plastic spacers

  Nair, A., McKinlay, L., Williamson, P., Short, P., Burns, P. & Lipworth, B. J., Jun 2017, In: European Journal of Clinical Pharmacology. 73, 6, p. 793-793 1 p.

  Research output: Contribution to journal › Article › peer-review

• FULFIL: an Unmet Need in Chronic Obstructive Pulmonary Disease

  Lipworth, B. J. & Jabbal, S., 15 Oct 2017, In: American Journal of Respiratory and Critical Care Medicine. 196, 8, p. 1082-1082 1 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File
  2 Citations (Scopus)

  112 Downloads (Pure)

• Homozygous status for the Arg16 variant is associated with increased prescribing of controller asthma medication and increased asthma-related prescribing cost

  Soares, P., Fidler, K., Tavendale, R., Turner, S., Lipworth, B., Bremner, S., Palmer, C. N. A. & Mukhopadhyay, S., Dec 2017, In: Clinical and Experimental Allergy. 47, 12, p. 1681-1682 2 p., O.010.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Impact of Spacers on Therapeutic Ratio with Inhaled Corticosteroids

  Lipworth, B. & Jabbal, S., 2017, In: The Journal of Allergy and Clinical Immunology: In Practice. 5, 4, p. 1163 1 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Citation (Scopus)

• Inhaled corticosteroid dose-response in asthma: Should we measure inflammation?

  Anderson, W. J., Short, P., Jabbal, S. & Lipworth, B., Feb 2017, In: Annals of Allergy, Asthma & Immunology. 118, 2, p. 179-185 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Architectural Accessibility
  • Adrenal Cortex Hormones
  • Asthma
  • Confidence Intervals
  • Inflammation
  7 Citations (Scopus)

  170 Downloads (Pure)

• Obesity and asthma – do we need expensive therapies?

  Anderson, W. & Lipworth, B., 25 Jan 2017, In: Thorax.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File
  29 Downloads (Pure)

• Reappraisal of the clinical effect of mepolizumab

  Lipworth, B. J. & Jabbal, S., Jun 2017, In: The Lancet Respiratory Medicine. 5, 6, p. e20

  Research output: Contribution to journal › Letter › peer-review

• Reappraising the clinical impact of mepolizumab

  Lipworth, B. J. & Jabbal, S., Jun 2017, In: Lancet. 5, 6, 1 p., e20.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File
  122 Downloads (Pure)

• Respiratory effect of beta-blockers in people with asthma and cardiovascular disease: population-based nested case control study

  Morales, D. R., Lipworth, B. J., Donnan, P. T., Jackson, C. & Guthrie, B., 27 Jan 2017, In: BMC Medicine. 15, 9 p., 18.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Case-Control Studies
  • Asthma
  • Cardiovascular Diseases
  • Population
  • Incidence
  33 Citations (Scopus)

  318 Downloads (Pure)

• The case for impulse oscillometry in the management of asthma in children and adults

  Galant, S. P., Komarow, H. D., Shin, H-W., Siddiqui, S. & Lipworth, B. J., Jun 2017, In: Annals of Allergy, Asthma & Immunology. 118, 6, p. 664-671 8 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Oscillometry
  • Asthma
  • Child
  • Spirometry
  • Lung
  41 Citations (Scopus)

  481 Downloads (Pure)

• Tolerability of Bisoprolol on Domiciliary Spirometry in COPD

  Jabbal, S. & Lipworth, B. J., 14 Oct 2017, In: Lung. 196, 1, p. 11-14 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Bisoprolol
  • Spirometry
  • Chronic Obstructive Pulmonary Disease
  • Adrenal Cortex Hormones
  • Muscarinic Antagonists
  195 Downloads (Pure)

• Un-diagnosing persistent adult asthma

  Lipworth, B. J. & Jabbal, S., 1 Nov 2017, In: European Respiratory Journal. 50, 5, 1701433.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File

  • Oscillometry
  • Asthma
  • Spirometry
  • Eosinophilia
  • Nitric Oxide
  6 Citations (Scopus)

  111 Downloads (Pure)
• 2018

  Adrenal suppression with inhaled corticosteroids: the seed and the soil

  Lipworth, B., Kuo, C. & Jabbal, S., 1 Jun 2018, In: The Lancet Respiratory Medicine. 6, 6, p. e19 1 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File
  1 Citation (Scopus)

  183 Downloads (Pure)

• Anti-interleukin 13 for asthma: stick or twist?

  Lipworth, B., Jabbal, S. & Kuo, C. R., Sep 2018, In: The Lancet Respiratory Medicine. 6, 9, p. e46-e47 2 p.

  Research output: Contribution to journal › Letter › peer-review
  3 Citations (Scopus)

• Asthma Step-Down Strategies: Perhaps the Patient Should Decide?

  Lipworth, B. & Israel, E., Mar 2018, In: The Journal of Allergy and Clinical Immunology: In Practice. 6, 2, p. 644-645 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  149 Downloads (Pure)

• Current appraisal of single inhaler triple therapy in COPD

  Lipworth, B., Kuo, R. W. & Jabbal, S., 28 Sep 2018, In: International Journal of Chronic Obstructive Pulmonary Disease. 13, 13, p. 3003-3009 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Muscarinic Antagonists
  • Nebulizers and Vaporizers
  • Chronic Obstructive Pulmonary Disease
  • Adrenal Cortex Hormones
  • fluticasone furoate
  16 Citations (Scopus)

  172 Downloads (Pure)

• Disconnection of pulmonary and systemic arterial stiffness in COPD

  Weir-McCall, J. R., Liu-Shiu-Cheong, P. S., Struthers, A. D., Lipworth, B. J. & Houston, J. G., 28 May 2018, In: International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 1755-1765 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Vascular Stiffness
  • Chronic Obstructive Pulmonary Disease
  • Pulse Wave Analysis
  • Lung
  • Healthy Volunteers
  1 Citation (Scopus)

  160 Downloads (Pure)

• Does the asthma visual analogue scale relate to the asthma control questionnaire?

  Jabbal, S. & Lipworth, B., 1 May 2018, In: Annals of Allergy, Asthma & Immunology. 120, 5, p. 533-535 3 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File

  • Visual Analog Scale
  • Asthma
  • Documentation
  • Guidelines
  117 Downloads (Pure)

• Effects of contrast administration on cardiac MRI volumetric, flow and pulse wave velocity quantification using manual and software-based analysis

  Fathi, A., Weir-McCall, J. R., Struthers, A. D., Lipworth, B. J. & Houston, J. G., 2018, In: British Journal of Radiology. 91, 1084, 14 p., 20170717.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pulse Wave Analysis
  • Gadolinium
  • Software
  • Contrast Media
  • gadoterate meglumine
  2 Citations (Scopus)

  191 Downloads (Pure)

• Improved lung function and patient-reported outcomes with co-suspension delivery technology glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a randomized Phase III study conducted in Asia, Europe, and the USA

  Lipworth, B. J., Collier, D. J., Gon, Y., Zhong, N., Nishi, K., Chen, R., Arora, S., Maes, A., Siddiqui, S., Reisner, C. & Martin, U. J., 26 Sep 2018, In: International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 2969-2984 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glycopyrrolate
  • Formoterol Fumarate
  • Metered Dose Inhalers
  • Patient Reported Outcome Measures
  • Chronic Obstructive Pulmonary Disease
  20 Citations (Scopus)

  143 Downloads (Pure)

• Inhaled triple therapy in chronic obstructive pulmonary disease

  Lipworth, B., Kuo, C. R. W. & Jabbal, S., 29 Sep 2018, In: The Lancet. 392, 10153, p. 1112-1113 2 p.

  Research output: Contribution to journal › Letter › peer-review

• Is small airways dysfunction related to asthma control and type 2 inflammation?

  Kuo, C. R., Jabbal, S. & Lipworth, B., Nov 2018, In: Annals of Allergy, Asthma & Immunology. 121, 5, p. 631-632 2 p.

  Research output: Contribution to journal › Letter › peer-review
  4 Citations (Scopus)

• Pulmonary and systemic arterial stiffness are disconnected in COPD

  Weir-McCall, J., Liu Shiu Cheong, P., Struthers, A., Lipworth, B. & Houston, J., 28 May 2018, In: International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 1755-1765 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Vascular Stiffness
  • Chronic Obstructive Pulmonary Disease
  • Lung
  • Healthy Volunteers
  • Biomarkers

• Pulmonary arterial stiffening in COPD and its implications for right ventricular remodelling.

  Weir-McCall, J. R., Liu Shiu Cheong, P. S. K., Struthers, A. D., Lipworth, B. J. & Houston, J. G., Aug 2018, In: European Radiology. 28, 8, p. 3464-3472 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ventricular Remodeling
  • Chronic Obstructive Pulmonary Disease
  • Pulse Wave Analysis
  • Lung
  • Stroke Volume
  3 Citations (Scopus)

  231 Downloads (Pure)

• Sensitivity of lung resistance and compliance to beta-blocker induced bronchoconstriction and long acting beta-agonist withdrawal in COPD

  Jabbal, S. & Lipworth, B. J., Feb 2018, In: Lung. 196, 1, p. 15-18 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Carvedilol
  • Lung Compliance
  • Bronchoconstriction
  • Oscillometry
  • Chronic Obstructive Pulmonary Disease
  3 Citations (Scopus)

  157 Downloads (Pure)

• Toll-like receptor 3 blockade in rhinovirus-induced experimental asthma exacerbations: A Randomized Controlled Study

  Silkoff, P. E., Flavin, S., Gordon, R., Loza, M. J., Sterk, P. J., Lutter, R., Diamant, Z., Turner, R. B., Lipworth, B. J., Proud, D., Singh, D., Eich, A., Backer, V., Gern, J. E., Herzmann, C., Halperin, S. A., Mensinga, T. T., Del Vecchio, A. M., Branigan, P., San Mateo, L. & 3 others, Baribaud, F., Barnathan, E. S. & Johnston, S. L., Apr 2018, In: Journal of Allergy and Clinical Immunology. 141, 4, p. 1220-1230 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Toll-Like Receptor 3
  • Rhinovirus
  • Asthma
  • Placebos
  • Healthy Volunteers
  18 Citations (Scopus)

  219 Downloads (Pure)

• What can we learn about COPD from impulse oscillometry?

  Lipworth, B. J. & Jabbal, S., 1 Jun 2018, In: Respiratory Medicine. 139, p. 106-109 4 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Oscillometry
  • Chronic Obstructive Pulmonary Disease
  • Bronchoconstriction
  • Airway Resistance
  • Bronchodilator Agents
  16 Citations (Scopus)

  221 Downloads (Pure)