Find Research Outputs

Search results

• Article

  Alcohol exposure induces chick craniofacial bone defects by negatively affecting cranial neural crest development

  Zhang, P., Wang, G., Lin, Z., Wu, Y., Zhang, J., Liu, M., Lee, K. K. H., Chuai, M. & Yang, X., 5 Nov 2017, In: Toxicology Letters. 281, p. 53-64 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Neural Crest
  • Bone
  • Ethanol
  • Alcohols
  • Defects
  11 Citations (Scopus)

  338 Downloads (Pure)

• Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer

  MacLeod, A. K., Acosta-Jimenez, L., Coates, P. J., McMahon, M., Carey, F. A., Honda, T., Henderson, C. J. & Wolf, C. R., 6 Dec 2016, In: British Journal of Cancer. 115, 12, p. 1530-1539 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Aldo-Keto Reductases
  • Non-Small Cell Lung Carcinoma
  • Biomarkers
  • Squamous Cell Carcinoma
  • Cell Line
  18 Citations (Scopus)

  232 Downloads (Pure)

• A Leptin Fragment Mirrors the Cognitive Enhancing and Neuroprotective Actions of Leptin

  Malekizadeh, Y., Holiday, A., Redfearn, D., Ainge, J. A., Doherty, G. & Harvey, J., 6 Sep 2016, In: Cerebral Cortex. 27, 10, p. 4769-4782 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Leptin
  • leptin (116-130)
  • Alzheimer Disease
  • leptin 22-56
  • Amyloid
  17 Citations (Scopus)

  159 Downloads (Pure)

• A leucine aminopeptidase is involved in kinetoplast DNA segregation in Trypanosoma brucei

  Peña-Diaz, P., Vancová, M., Resl, C., Field, M. C. & Lukeš, J., 7 Apr 2017, In: PLoS Pathogens. 13, 4, p. 1-23 23 p., e1006310.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Kinetoplast DNA
  • Leucyl Aminopeptidase
  • Trypanosoma brucei brucei
  • Cytokinesis
  • Ectopic Gene Expression
  12 Citations (Scopus)

  223 Downloads (Pure)

• Alfvénic wave heating of the upper chromosphere in flares

  Reep, J. W. & Russell, A. J. B., 9 Feb 2016, In: Astrophysical Journal Letters. 818, 1, p. 1-5 5 p., L20.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • chromosphere
  • flares
  • heating
  • corona
  • coronas
  38 Citations (Scopus)

  147 Downloads (Pure)

• Algae as nutritional and functional food sources: revisiting our understanding

  Wells, M. L., Potin, P., Craigie, J. S., Raven, J. A., Merchant, S. S., Helliwell, K. E., Smith, A. G., Camire, M. E. & Brawley, S. H., Apr 2017, In: Journal of Applied Phycology. 29, 2, p. 949-982 34 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • functional food
  • functional foods
  • alga
  • algae
  • nutritive value
  359 Citations (Scopus)

  296 Downloads (Pure)

• Allelic diversity of S-RNase alleles in diploid potato species

  Dzidzienyo, D. K., Bryan, G. J., Wilde, G. & Robbins, T. P., Oct 2016, In: Theoretical and Applied Genetics. 129, 10, p. 1985-2001 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • ribonuclease S
  • Solanum tuberosum
  • allelic variation
  • Ribonucleases
  • ribonucleases
  4 Citations (Scopus)

  184 Downloads (Pure)

• Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation

  Orriss, I. R., Arnett, T. R., George, J. & Witham, M. D., 15 Mar 2016, In: Experimental Cell Research. 342, 2, p. 166-174 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Oxypurinol
  • Allopurinol
  • Xanthine Oxidase
  • Osteoblasts
  • Osteogenesis
  10 Citations (Scopus)

  163 Downloads (Pure)

• Allosteric targeting of the Fanconi anemia ubiquitin-conjugating enzyme Ube2T by fragment screening

  Morreale, F., Bortoluzzi, A., Chaugule, V., Arkinson, C., Walden, H. & Ciulli, A., 11 May 2017, In: Journal of Medicinal Chemistry. 60, 9, p. 4093-4098 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ubiquitin-Conjugating Enzymes
  • Fanconi Anemia
  • DNA Repair
  • Binding Sites
  • In Vitro Techniques
  9 Citations (Scopus)

  204 Downloads (Pure)

• Alloyed quaternary/binary core/shell quantum dot-graphene oxide nanocomposite: Preparation, characterization and application as a fluorescence “switch ON” probe for environmental pollutants

  Adegoke, O., Montaseri, H., Nsibande, S. A. & Forbes, P. B. C., 5 Oct 2017, In: Journal of Alloys and Compounds. 720, p. 70-78 9 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• All patients with diabetes should have annual UACR tests. Why is that so hard?

  Willison, A., Tully, V. & Davey, P., 20 Sep 2016, In: BMJ Quality Improvement Reports. 5, 1, 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Albumins
  • Creatinine
  • Urine
  • Patient Participation
  • Kidney Diseases
  161 Downloads (Pure)

• AlmostSignificant: simplifying quality control of high-throughput sequencing data

  Ward, J., Cole, C., Febrer, M. & Barton, G. J., 15 Dec 2016, In: Bioinformatics. 32, 24, p. 3850-3851 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • High Throughput
  • Sequencing
  • Quality Control
  • DNA Sequence Analysis
  • Quality control
  2 Citations (Scopus)

  109 Downloads (Pure)

• A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

  Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 242 others, Teslovich, T. M., Blackwell, T. W., Bork-Jensen, J., Burtt, N. P., Chen, Y., Green, T., Hartl, C., Kang, H. M., Kumar, A., Ladenvall, C., Ma, C., Moutsianas, L., Pearson, R. D., Perry, J. R. B., Rayner, N. W., Robertson, N. R., Scott, L. J., van de Bunt, M., Eriksson, J. G., Jula, A., Koskinen, S., Lehtimäki, T., Palotie, A., Raitakari, O. T., Jacobs, S. B., Wessel, J., Chu, A. Y., Scott, R. A., Goodarzi, M. O., Blancher, C., Buck, G., Buck, D., Chines, P. S., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Trakalo, J., Banks, E., Carey, J., Carneiro, M. O., DePristo, M., Farjoun, Y., Fennell, T., Goldstein, J. I., Grant, G., Hrabé de Angelis, M., Maguire, J., Neale, B. M., Poplin, R., Purcell, S., Schwarzmayr, T., Shakir, K., Smith, J. D., Strom, T. M., Wieland, T., Lindstrom, J., Brandslund, I., Christensen, C., Surdulescu, G. L., Lakka, T. A., Doney, A. S. F., Nilsson, P., Wareham, N. J., Langenberg, C., Varga, T. V., Franks, P. W., Rolandsson, O., Rosengren, A. H., Farook, V. S., Thameem, F., Puppala, S., Kumar, S., Lehman, D. M., Jenkinson, C. P., Curran, J. E., Fowler, S. P., Arya, R., DeFronzo, R. A., Abboud, H. E., Syvänen, A-C., Hicks, P. J., Palmer, N. D., Ng, M. C. Y., Bowden, D. W., Freedman, B. I., Esko, T., Mägi, R., Milani, L., Mihailov, E., Metspalu, A., Narisu, N., Kinnunen, L., Bonnycastle, L. L., Swift, A., Pasko, D., Wood, A. R., Fadista, J., Pollin, T. I., Barzilai, N., Atzmon, G., Glaser, B., Thorand, B., Strauch, K., Peters, A., Roden, M., Müller-Nurasyid, M., Liang, L., Kriebel, J., Illig, T., Grallert, H., Gieger, C., Meisinger, C., Lannfelt, L., Musani, S. K., Griswold, M., Taylor, H. A., Wilson, G., Correa, A., Oksa, H., Scott, W. R., Afzal, U., Tan, S-T., Loh, M., Chambers, J. C., Sehmi, J., Kooner, J. S., Lehne, B., Cho, Y. S., Lee, J-Y., Han, B-G., Käräjämäki, A., Qi, Q., Qi, L., Huang, J., Hu, F. B., Melander, O., Orho-Melander, M., Below, J. E., Aguilar, D., Wong, T. Y., Liu, J., Khor, C-C., Chia, K. S., Lim, W. Y., Cheng, C-Y., Chan, E., Tai, E. S., Aung, T., Linneberg, A., Isomaa, B., Meitinger, T., Tuomi, T., Hakaste, L., Kravic, J., Jørgensen, M. E., Lauritzen, T., Deloukas, P., Stirrups, K. E., Owen, K. R., Farmer, A. J., Frayling, T. M., O'Rahilly, S. P., Walker, M., Levy, J. C., Hodgkiss, D., Hattersley, A. T., Kuulasmaa, T., Stančáková, A., Barroso, I., Bharadwaj, D., Chan, J., Chandak, G. R., Daly, M. J., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Fingerlin, T., Froguel, P., Hu, C., Jia, W., Ma, R. C. W., McVean, G., Park, T., Prabhakaran, D., Sandhu, M., Scott, J., Sladek, R., Tandon, N., Teo, Y. Y., Zeggini, E., Watanabe, R. M., Koistinen, H. A., Kesaniemi, Y. A., Uusitupa, M., Spector, T. D., Salomaa, V., Rauramaa, R., Palmer, C. N. A., Prokopenko, I., Morris, A. D., Bergman, R. N., Collins, F. S., Lind, L., Ingelsson, E., Tuomilehto, J., Karpe, F., Groop, L., Jørgensen, T., Hansen, T., Pedersen, O., Kuusisto, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Seielstad, M., Wilson, J. G., Dupuis, J., Ripatti, S., Hanis, C. L., Florez, J. C., Mohlke, K. L., Meigs, J. B., Laakso, M., Morris, A. P., Boehnke, M., Altshuler, D., McCarthy, M. I., Gloyn, A. L. & Lindgren, C. M., Jul 2017, In: Diabetes. 66, 7, p. 2019-2032 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Fasting
  • Type 2 Diabetes Mellitus
  • Insulin
  • Exome
  • Population
  23 Citations (Scopus)

  39 Downloads (Pure)

• Altered metabolic parameters in association with antipsychotic medication use in diabetes: A population based case-control study

  Wake, D. J., Broughton, P., Perera, S. M., MacIntyre, D. J. & Leese, G. P., Apr 2016, In: Psychoneuroendocrinology. 66, p. 214-220 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Antipsychotic Agents
  • Case-Control Studies
  • Schizophrenia
  • Population
  • Prescriptions
  5 Citations (Scopus)

  173 Downloads (Pure)

• Alternate thermoregulation and functional binding of Escherichia coli type 1 fimbriae in environmental and animal isolates

  Marshall, J., Rossez, Y., Mainda, G., Gally, D. L., Daniell, T. J. & Holden, N. J., Nov 2016, In: FEMS Microbiology Letters. 363, 22, p. 1-8 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Mannans
  • Body Temperature Regulation
  • Plant Roots
  • Temperature
  • Escherichia coli
  4 Citations (Scopus)

• Alternative caries management options for primary molars: 2.5-yr outcomes of a randomised clinical trial

  Santamaria, R. M., Innes, N., Machiulskiene, V., Schmoeckel, J., Alkilzy, M. & Splieth, C. H., 20 Dec 2017, In: Caries Research. 51, 6, p. 605-614

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Randomized Controlled Trials
  • Pulpitis
  • Nonparametric Statistics
  • Compomers
  • Therapeutics
  39 Citations (Scopus)

  292 Downloads (Pure)

• Alternative splicing of barley clock genes in response to low temperature: evidence for alternative splicing conservation

  Calixto, C. P. G., Simpson, C. G., Waugh, R. & Brown, J. W. S., 13 Dec 2016, In: PLoS ONE. 11, 12, p. 1-24 24 p., e0168028.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Hordeum
  • alternative splicing
  • Alternative Splicing
  • Conservation
  • Genes
  10 Citations (Scopus)

  162 Downloads (Pure)

• Alternatives to imprisonment in Scotland: policy, strategy and practice

  Freeman, R. & Lloyd, G., 19 Dec 2016, In: Criminology, Victimology and Security Review. 10, 3, p. 60-72

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • imprisonment
  • child custody
  • offense
  • adulthood
  • correctional institution
  543 Downloads (Pure)

• A matched comparison study of hepatitis C treatment outcomes in the prison and community setting, and an analysis of the impact of prison release or transfer during therapy

  Aspinall, E. J., Mitchell, W., Schofield, J., Cairns, A., Lamond, S., Bramley, P., Peters, S. E., Valerio, H., Tomnay, J., Goldberg, D. J., Mills, P. R., Barclay, S. T., Fraser, A., Dillon, J. F., Martin, N. K., Hickman, M. & Hutchinson, S. J., Dec 2016, In: Journal of Viral Hepatitis. 23, 12, p. 1009-1016 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Prisons
  • Hepatitis C
  • Prisoners
  • Therapeutics
  • Antiviral Agents
  28 Citations (Scopus)

  190 Downloads (Pure)

• A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis

  Naeem, A. S., Tommasi, C., Cole, C., Brown, S. J., Zhu, Y., Way, B., Willis Owen, S. A. G., Moffatt, M., Cookson, W. O., Harper, J. I., Di, W. L., Brown, S. J., Reinheckel, T. & O'Shaughnessy, R. F. L., Apr 2017, In: Journal of Allergy and Clinical Immunology. 139, 4, p. 1228-1241 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cathepsin H
  • Mechanistic Target of Rapamycin Complex 2
  • filaggrin
  • Mechanistic Target of Rapamycin Complex 1
  • Thymoma
  10 Citations (Scopus)

  214 Downloads (Pure)

• A meta-ethnography of the facilitators and barriers to successful implementation of patient complaints processes in health-care settings

  Scott, D. & Grant, S. M., Apr 2018, In: Health Expectations. 21, 2, p. 508-517 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cultural Anthropology
  • Delivery of Health Care
  • Social Responsibility
  • New Zealand
  • Sweden
  5 Citations (Scopus)

  201 Downloads (Pure)

• A method for automatic segmentation and splitting of hyperspectral images of raspberry plants collected in field conditions

  Williams, D., Britten, A., McCallum, S., Jones, H., Aitkenhead, M., Karley, A., Loades, K., Prashar, A. & Graham, J., 1 Nov 2017, In: Plant Methods. 13, p. 1-12 12 p., 74.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Rubus
  • hyperspectral imagery
  • raspberries
  • methodology
  • reflectance
  9 Citations (Scopus)

  170 Downloads (Pure)

• A methodological approach to assess the hazard of underground cavities subjected to environmental weathering

  Castellanza, R., Lollino, P. & Ciantia, M., Dec 2018, In: Tunnelling and Underground Space Technology. 82, p. 278-292 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Weathering
  • Hazards
  • cavity
  • Rocks
  • weathering
  6 Citations (Scopus)

  41 Downloads (Pure)

• A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies

  Bodea, C. A., Neale, B. M., Ripke, S., International IBD Genetics Consortium, Daly, M. J., Devlin, B. & Roeder, K., 5 May 2016, In: American Journal of Human Genetics. 98, 5, p. 857-868 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Genetic Structures
  • Gene Frequency
  • Case-Control Studies
  • Multifactorial Inheritance
  • Bayes Theorem
  6 Citations (Scopus)

• Amine Containing Analogs of Sulindac for Cancer Prevention

  Mathew, B., Hobrath, J. V., Connelly, M. C., Guy, R. K. & Reynolds, R. C., 31 Jan 2018, In: Open Medicinal Chemistry Journal. 12, p. 1-12 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Sulindac
  • sulindac sulfide amide
  • Amines
  • Libraries
  • 3-(5-nitrofuryl)-7-(5-nitrofurfurylidene)-3,3a,4,5,6,7-hexahydro-2H-indazole
  152 Downloads (Pure)

• Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

  Loftus, R. M., Assmann, N., Kedia-Mehta, N., O'Brien, K. L., Garcia, A., Gillespie, C., Hukelmann, J. L., Oefner, P. J., Lamond, A. I., Gardiner, C. M., Dettmer, K., Cantrell, D. A., Sinclair, L. V. & Finlay, D. K., 14 Jun 2018, In: Nature Communications. 9, 1, p. 1-15 15 p., 2341.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Oxidative Phosphorylation
  • amino acids
  • mice
  • Lymphocytes
  • Natural Killer Cells
  60 Citations (Scopus)

  171 Downloads (Pure)

• A Mixed Analytical/Numerical Method for Velocity and Heat Transfer of Laminar Power-Law Fluids

  Li, B., Zheng, L., Lin, P., Wang, Z. & Liao, M., 3 Aug 2016, In: Numerical Mathematics: Theory, Methods and Applications. 9, 3, p. 315-336 22 p.

  Research output: Contribution to journal › Article › peer-review

  • Power-law Fluid
  • Analytical Methods
  • Heat Transfer
  • Boundary layers
  • Boundary Layer
  6 Citations (Scopus)

• A mixed-methods feasibility study protocol to assess the communication behaviours within the dental health professional-parent-child triad in a general dental practice setting

  Yuan, S., Humphris, G. M., Ross, A., MacPherson, L., Zhou, Y. & Freeman, R., 13 Aug 2018, In: Pilot and Feasibility Studies. 4, p. 1-9 9 p., 136.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Dental General Practices
  • Feasibility Studies
  • Communication
  • Tooth
  • Health
  3 Citations (Scopus)

  174 Downloads (Pure)

• A Model for (Quasi-)Periodic Multiwavelength Photometric Variability in Young Stellar Objects

  Kesseli, A. Y., Petkova, M. A., Wood, K., Whitney, B. A., Hillenbrand, L. A., Gregory, S. G., Stauffer, J. R., Morales-Calderon, M., Rebull, L. & Alencar, S. H. P., Sep 2016, In: Astrophysical Journal. 828, 1, p. 1-15 15 p., 42.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • hot spot
  • young
  • light curve
  • accretion
  • stars
  8 Citations (Scopus)

  82 Downloads (Pure)

• A model of consultation in prostate cancer care: evidence from a systematic review

  Paterson, C. & Nabi, G., 2017, In: Cancer Nursing. 40, 4, p. 276-288 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Prostatic Neoplasms
  • Systematic Reviews
  • Referral and Consultation
  • Self-Management
  • Nurse Specialists
  13 Citations (Scopus)

  380 Downloads (Pure)

• A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors

  Harrison, J. R., Brand, S., Smith, V., Robinson, D. A., Thompson, S., Smith, A., Davies, K., Mok, N., Torrie, L. S., Collie, I., Hallyburton, I., Norval, S., Simeons, F. R. C., Stojanovski, L., Frearson, J. A., Brenk, R., Wyatt, P. G., Gilbert, I. H. & Read, K. D., 12 Sep 2018, In: Journal of Medicinal Chemistry. 61, 18, p. 8374–8389 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • glycylpeptide N-tetradecanoyltransferase
  • African Trypanosomiasis
  • Crystallography
  • Trypanosoma brucei brucei
  • Central Nervous System Diseases
  18 Citations (Scopus)

  198 Downloads (Pure)

• A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1

  Liu, Y., Freeman, A. D. J., Déclais, A-C. & Lilley, D. M. J., 16 Nov 2018, In: Nucleic Acids Research. 46, 20, p. 11089-11098 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ions
  • DNA
  • Substrate Specificity
  • Enzymes
  • Catalytic Domain
  3 Citations (Scopus)

  110 Downloads (Pure)

• A Morphological identification cell cytotoxicity assay using cytoplasm-localized fluorescent probe (CLFP) to distinguish living and dead cells

  Lai, F., Shen, Z., Wen, H., Chen, J., Zhang, X., Lin, P., Yin, D., Cui, H. & Chen, X., 8 Jan 2017, In: Biochemical and Biophysical Research Communications. 482, 2, p. 257-263 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cytotoxicity
  • Assays
  • Fluorescent Dyes
  • Cytoplasm
  • Cells
  10 Citations (Scopus)

  400 Downloads (Pure)

• A moving interface finite element formulation for layered structures

  Funari, M. F., Greco, F. & Lonetti, P., 1 Jul 2016, In: Composites Part B: Engineering. 96, p. 325-337 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Debonding
  • Crack propagation
  • Composite materials
  33 Citations (Scopus)

• AMP-activated protein kinase: a cellular energy sensor that comes in twelve flavours

  Ross, F. A., MacKintosh, C. & Hardie, D. G., 24 Mar 2016, In: FEBS Journal. 283, 16, p. 2987-3001 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Flavors
  • AMP-Activated Protein Kinases
  • Protein Isoforms
  • Gene encoding
  • Tumors
  136 Citations (Scopus)

  112 Downloads (Pure)

• AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner

  Vlachaki Walker, J. M., Robb, J. L., Cruz, A. M., Malhi, A., Weightman Potter, P. G., Ashford, M. L. J., McCrimmon, R. J., Ellacott, K. L. J. & Beall, C., 21 Apr 2017, In: Diabetes, Obesity & Metabolism. 19, 7, p. 997-1005 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • A 769662
  • AMP-Activated Protein Kinases
  • Astrocytes
  • Adenosine Triphosphate
  • Calcium
  14 Citations (Scopus)

  290 Downloads (Pure)

• AMP-activated protein kinase inhibits K_v1.5 channel currents of pulmonary arterial myocytes in response to hypoxia and inhibition of mitochondrial oxidative phosphorylation

  Moral-Sanz, J., Mahmoud, A. D., Ross, F. A., Eldstrom, J., Fedida, D., Hardie, D. G. & Evans, A. M., 1 Sep 2016, In: Journal of Physiology. 594, 17, p. 4901-4915 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Oxidative Phosphorylation
  • Muscle Cells
  • Hypoxia
  • Lung
  16 Citations (Scopus)

  157 Downloads (Pure)

• AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B

  Johanns, M., Lai, Y. C., Hsu, M. F., Jacobs, R., Vertommen, D., Van Sande, J., Dumont, J. E., Woods, A., Carling, D., Hue, L., Viollet, B., Foretz, M. & Rider, M. H., 8 Mar 2016, In: Nature Communications. 7, 10856.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • cyclic AMP
  • Phosphorylation
  • adenosine monophosphate
  • Type 4 Cyclic Nucleotide Phosphodiesterase
  • phosphorylation
  54 Citations (Scopus)

• AMPK Causes Cell Cycle Arrest in LKB1-deficient Cells via Activation of CAMKK2

  Fogarty, S., Ross, F. A., Vara Ciruelos, D., Gray, A., Gowans, G. J. & Hardie, D. G., 1 Aug 2016, In: Molecular Cancer Research. 14, 8, p. 683-695 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Cell Cycle Checkpoints
  • Null Lymphocytes
  • Calcimycin
  • Phosphorylation
  34 Citations (Scopus)

  311 Downloads (Pure)

• Amputation-free survival in 17,353 people at high risk for foot ulceration in diabetes: a national observational study

  Scottish Diabetes Research Network Epidemiology Group, Vadiveloo, T., Jeffcoate, W., Donnan, P. T., Colhoun, H. C., McGurnaghan, S., Wild, S., McCrimmon, R. & Leese, G. P., Dec 2018, In: Diabetologia. 61, 12, p. 2590-2597 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Amputation
  • Ulcer
  • Foot
  • Observational Studies
  • Scotland
  15 Citations (Scopus)

  188 Downloads (Pure)

• A Multicellular Model of Intestinal Crypt Buckling and Fission

  Almet, A. A., Hughes, B. D., Landman, K. A., Näthke, I. S. & Osborne, J. M., Feb 2018, In: Bulletin of Mathematical Biology. 80, 2, p. 335-359 25 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • intestinal crypts
  • buckling
  • Buckling
  • Organoids
  • Tissue
  3 Citations (Scopus)

  228 Downloads (Pure)

• A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13

  Leslie, E. J., Carlson, J. C., Shaffer, J. R., Feingold, E., Wehby, G., Laurie, C. A., Jain, D., Laurie, C. C., Doheny, K. F., McHenry, T., Resick, J., Sanchez, C., Jacobs, J., Emanuele, B., Vieira, A. R., Neiswanger, K., Lidral, A. C., Valencia-Ramirez, L. C., Lopez-Palacio, A. M., Valencia, D. R. & 35 others, Arcos-Burgos, M., Czeizel, A. E., Field, L. L., Padilla, C. D., Cutiongco-de la Paz, E. M. C., Deleyiannis, F., Christensen, K., Munger, R. G., Lie, R. T., Wilcox, A., Romitti, P. A., Castilla, E. E., Mereb, J. C., Poletta, F. A., Orioli, I. M., Carvalho, F. M., Hecht, J. T., Blanton, S. H., Buxó, C. J., Butali, A., Mossey, P. A., Adeyemo, W. L., James, O., Braimah, R. O., Aregbesola, B. S., Eshete, M. A., Abate, F., Koruyucu, M., Seymen, F., Ma, L., de Salamanca, J. E., Weinberg, S. M., Moreno, L., Murray, J. C. & Marazita, M. L., 1 Jul 2016, In: Human Molecular Genetics. 25, 13, p. 2862-2872 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cleft Lip
  • Cleft Palate
  • Genome-Wide Association Study
  • Genes
  • Actin Cytoskeleton
  86 Citations (Scopus)

• A multifaceted approach to identify non-specific enzyme inhibition: Application to Mycobacterium tuberculosis shikimate kinase

  Alturki, M. S., Fuanta, N. R., Jarrard, M. A., Hobrath, J. V., Goodwin, D. C., Rants'o, T. A. & Calderón, A. I., 15 Feb 2018, In: Bioorganic and Medicinal Chemistry Letters. 28, 4, p. 802-808 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • shikimate kinase
  • Enzyme inhibition
  • Assays
  • Mycobacterium tuberculosis
  • Screening
  6 Citations (Scopus)

  159 Downloads (Pure)

• A multiscale mathematical model of tumour invasive growth

  Peng, L., Trucu, D., Lin, P., Thompson, A. & Chaplain, M. A. J., Mar 2017, In: Bulletin of Mathematical Biology. 79, 3, p. 389-429 41 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Multiscale Model
  • Tumor
  • tumor
  • Tumors
  • Cancer
  17 Citations (Scopus)

  172 Downloads (Pure)

• A multispecialty study of determining the possibility of pregnancy and the documentation of pregnancy status in surgical patients: a cause for concern?

  Ibrahim, I., Ibrahim, B., Yong, G. L., Coats, M., Vujovic, Z. & Wilson, M. S. J., 1 Nov 2018, In: Scottish Medical Journal. 63, 4, p. 108-112 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Documentation
  • Pregnancy
  • Surgical Specialties
  • Neurosurgery
  • Gynecology

• A mutant O-GlcNAcase enriches Drosophila developmental regulators

  Selvan, N., Williamson, R., Mariappa, D., Campbell, D. G., Gourlay, R., Ferenbach, A. T., Aristotelous, T., Hopkins-Navratilova, I., Trost, M. & van Aalten, D. M. F., Aug 2017, In: Nature Chemical Biology. 13, 8, p. 882-887 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • hexosaminidase C
  • O-GlcNAc transferase
  • Drosophila
  • Embryonic Development
  • Proteins
  22 Citations (Scopus)

  199 Downloads (Pure)

• Anabolic resistance does not explain sarcopenia in patients with type 2 diabetes mellitus, compared with healthy controls, despite reduced mTOR pathway activity

  Cuthbertson, D. J., Babraj, J., Leese, G. & Siervo, M., Dec 2017, In: Clinical Nutrition. 36, 6, p. 1716-1719 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Sarcopenia
  • Type 2 Diabetes Mellitus
  • Essential Amino Acids
  • Muscles
  • TOR Serine-Threonine Kinases
  6 Citations (Scopus)

• An active DNA-based nanoprobe for photoacoustic pH imaging

  Baumann, K. N., Fux, A. C., Joseph, J., Bohndiek, S. E. & Hernández-Ainsa, S., 2018, In: Chemical Communications. 54, 72, p. 10176-10178 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Nanoprobes
  • Photoacoustic effect
  • Imaging techniques
  • DNA
  • Phantoms
  3 Citations (Scopus)

  8 Downloads (Pure)

• An acute transfusion reaction

  Webb, C., Norris, A. & Hands, K., 1 Feb 2018, In: Clinical Medicine - Journal of the Royal College of Physicians of London. 18, 1, p. 95-97 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • anti-IgA
  • Transfusion Reaction
  • Anti-Idiotypic Antibodies
  • Blood Component Transfusion
  • IgA Deficiency
  1 Citation (Scopus)

• Anaesthesia for laryngo-tracheal surgery, including tubeless field techniques

  Pearson, K. L. & McGuire, B. E., 1 Jul 2017, In: BJA Education. 17, 7, p. 242-248 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Anesthesia
  • Airway Management
  • Safety
  • Laser Therapy
  • Larynx
  6 Citations (Scopus)