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  • 2019
  • 2018
  • 2017
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  • Louise Donnelly
2019

A Type 1 Diabetes Genetic Risk Score Can Identify Patients With GAD65 Autoantibody-Positive Type 2 Diabetes Who Rapidly Progress to Insulin Therapy

Grubb, A. L., McDonald, T. J., Rutters, F., Donnelly, L., Hattersley, A. T., Oram, R. A., Palmer, C., van der Heijden, A. A., Carr, F., Elders, P. J. M., Weedon, M., Slieker, R. C., 't Hart, L. M., Pearson, E., Shields, B. M. & Jones, A. G., 1 Feb 2019, In : Diabetes Care. 42, 2, p. 208-214 7 p.

Research output: Contribution to journalArticle

Open Access
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8 Citations (Scopus)
344 Downloads (Pure)

Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration

Wilman, H. R., Parisinos, C. A., Atabaki-Pasdar, N., Kelly, M., Thomas, E. L., Neubauer, S., Mahajan, A., Hingorani, A. D., Patel, R. S., Hemingway, H., Franks, P. W., Bell, J. D., Banerjee, R. & Yaghootkar, H., Sep 2019, In : Journal of Hepatology. 71, 3, p. 594-602 9 p.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
67 Downloads (Pure)
2018

Characteristics of people with high visit-to-visit glycaemic variability in Type 2 diabetes

Noyes, J. D., Soto-Pedre, E., Donnelly, L. A. & Pearson, E., 14 Jan 2018, In : Diabetic Medicine. 35, 2, p. 262-267 6 p.

Research output: Contribution to journalArticle

Open Access
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9 Citations (Scopus)
140 Downloads (Pure)

Cohort Profile: Genetics of Diabetes Audit and Research in Tayside Scotland (GoDARTS)

Hébert, H. L., Shepherd, B., Milburn, K., Veluchamy, A., Meng, W., Carr, F., Donnelly, L. A., Tavendale, R., Leese, G., Colhoun, H. M., Dow, E., Morris, A. D., Doney, A. S., Lang, C. C., Pearson, E. R., Smith, B. H. & Palmer, C. N. A., 1 Apr 2018, In : International Journal of Epidemiology. 47, 2, p. 380-381j 12 p.

Research output: Contribution to journalArticle

Open Access
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11 Citations (Scopus)
205 Downloads (Pure)
2017

Acute kidney injury, plasma lactate concentrations and lactic acidosis in metformin users: A GoDarts study

Connelly, P. J., Lonergan, M., Soto-Pedre, E., Donnelly, L., Zhou, K. & Pearson, E. R., 5 Jul 2017, In : Diabetes, Obesity & Metabolism. 19, 11, p. 1579-1586 7 p.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
146 Downloads (Pure)
Open Access
File
8 Citations (Scopus)
130 Downloads (Pure)

Mapping Local Codes to Read Codes

Bonney, W., Galloway, J., Hall, C., Ghattas, M., Tramma, L., Nind, T., Donnelly, L., Jefferson, E. & Doney, A., 2017, Building Capacity for Health Informatics in the Future. Lau, F., Bartle-Clar, J., Bliss, G., Borycki, E., Courtney, K. & Kuo, A. (eds.). Amsterdam: IOS Press, p. 29-36 8 p. (Studies in Health Technology and Informatics; vol. 234).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Open Access
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2 Citations (Scopus)
96 Downloads (Pure)

Quantifying the extent to which index event biases influence large genetic association studies

Yaghootkar, H., Bancks, M. P., Jones, S. E., McDaid, A., Beaumont, R., Donnelly, L., Wood, A. R., Campbell, A., Tyrrell, J., Hocking, L. J., Tuke, M. A., Ruth, K. S., Pearson, E. R., Murray, A., Freathy, R. M., Munroe, P. B., Hayward, C., Palmer, C., Weedon, M. N., Pankow, J. S. & 2 others, Frayling, T. M. & Kutalik, Z., 1 Jun 2017, In : Human Molecular Genetics. 26, 5, p. 1018-1030 13 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
121 Downloads (Pure)

Rates of glycaemic deterioration in a real-world population with type 2 diabetes

Donnelly, L. A., Zhou, K., Doney, A. S. F., Jennison, C., Franks, P. W. & Pearson, E. R., 19 Dec 2017, In : Diabetologia. 61, p. 607-615 9 p.

Research output: Contribution to journalArticle

Open Access
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12 Citations (Scopus)
164 Downloads (Pure)

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

Webb, T. R., Erdmann, J., Stirrups, K. E., Stitziel, N. O., Masca, N. G. D., Jansen, H., Kanoni, S., Nelson, C. P., Ferrario, P. G., König, I. R., Eicher, J. D., Johnson, A. D., Hamby, S. E., Betsholtz, C., Ruusalepp, A., Franzén, O., Schadt, E. E., Björkegren, J. L. M., Weeke, P. E., Auer, P. L. & 31 others, Schick, U. M., Lu, Y., Zhang, H., Dube, M-P., Goel, A., Farrall, M., Peloso, G. M., Won, H-H., Do, R., van Iperen, E., Kruppa, J., Mahajan, A., Scott, R. A., Willenborg, C., Braund, P. S., van Capelleveen, J. C., Doney, A. S. F., Donnelly, L. A., Asselta, R., Merlini, P. A., Duga, S., Marziliano, N., Denny, J. C., Shaffer, C., El-Mokhtari, N. E., Franke, A., Heilmann, S., Hengstenberg, C., Morris, A. D., Palmer, C. N. A. & Wellcome Trust Case Control Consortium, MORGAM Investigators, Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators, 21 Feb 2017, In : Journal of the American College of Cardiology. 69, 7, p. 823-836 14 p.

Research output: Contribution to journalArticle

Open Access
File
91 Citations (Scopus)
129 Downloads (Pure)
2016

Adherence to oral glucose-lowering therapies and associations with 1-year HbA1c: A retrospective cohort analysis in a large primary care database

Farmer, A. J., Rodgers, L. R., Lonergan, M., Shields, B., Weedon, M. N., Donnelly, L., Holman, R. R., Pearson, E. R. & Hattersley, A. T., 1 Feb 2016, In : Diabetes Care. 39, 2, p. 258-263 6 p.

Research output: Contribution to journalArticle

Open Access
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37 Citations (Scopus)
131 Downloads (Pure)

Coding variation in ANGPTL4, LPL, and SVEP1 and the risk of coronary disease

Stitziel, N. O., Stirrups, K. E., Masca, N. G. D., Erdmann, J., Ferrario, P. G., König, I. R., Weeke, P. E., Webb, T. R., Auer, P. L., Schick, U. M., Lu, Y., Zhang, H., Dube, M. P., Goel, A., Farrall, M., Peloso, G. M., Won, H. H., Do, R., Van Iperen, E., Kanoni, S. & 109 others, Kruppa, J., Mahajan, A., Scott, R. A., Willenborg, C., Braund, P. S., Van Capelleveen, J. C., Doney, A. S. F., Donnelly, L. A., Asselta, R., Merlini, P. A., Duga, S., Marziliano, N., Denny, J. C., Shaffer, C. M., El-Mokhtari, N. E., Franke, A., Gottesman, O., Heilmann, S., Hengstenberg, C., Hoffmann, P., Holmen, O. L., Hveem, K., Jansson, J. H., Jöckel, K. H., Kessler, T., Kriebel, J., Laugwitz, K. L., Marouli, E., Martinelli, N., McCarthy, M. I., van Zuydam, N. R., Meisinger, C., Esko, T., Mihailov, E., Escher, S. A., Alver, M., Moebus, S., Morris, A. D., Müller-Nurasyid, M., Nikpay, M., Olivieri, O., Perreault, L. P. L., AlQarawi, A., Robertson, N. R., Akinsanya, K. O., Reilly, D. F., Vogt, T. F., Yin, W., Asselbergs, F. W., Kooperberg, C., Jackson, R. D., Stahl, E., Strauch, K., Varga, T. V., Waldenberger, M., Zeng, L., Kraja, A. T., Liu, C., Ehret, G. B., Newton-Cheh, C., Chasman, D. I., Chowdhury, R., Ferrario, M., Ford, I., Jukema, J. W., Kee, F., Kuulasmaa, K., Nordestgaard, B. G., Perola, M., Saleheen, D., Sattar, N., Surendran, P., Tregouet, D., Young, R., Howson, J. M. M., Butterworth, A. S., Danesh, J., Ardissino, D., Bottinger, E. P., Erbel, R., Franks, P. W., Girelli, D., Hall, A. S., Hovingh, G. K., Kastrati, A., Lieb, W., Meitinger, T., Kraus, W. E., Shah, S. H., McPherson, R., Orho-Melander, M., Melander, O., Metspalu, A., Palmer, C. N. A., Peters, A., Rader, D. J., Reilly, M. P., Loos, R. J. F., Reiner, A. P., Roden, D. M., Tardif, J. C., Thompson, J. R., Wareham, N. J., Watkins, H., Willer, C. J., Kathiresan, S., Deloukas, P., Samani, N. J. & Schunkert, H., 24 Mar 2016, In : New England Journal of Medicine. 374, 12, p. 1134-1144 11 p.

Research output: Contribution to journalArticle

Open Access
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219 Citations (Scopus)
282 Downloads (Pure)

CYP2C8 and SLCO1B1 variants and therapeutic response to thiazolidinediones in patients with type 2 diabetes.

Dawed, A. Y., Donnelly, L., Tavendale, R., Carr, F., Leese, G., Palmer, C. N. A., Pearson, E. & Zhou, K., Nov 2016, In : Diabetes Care. 39, 11, p. 1902-1908 7 p.

Research output: Contribution to journalArticle

Open Access
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23 Citations (Scopus)
186 Downloads (Pure)

Genetic evidence for a link between favorable adiposity and lower risk of type 2 diabetes, hypertension and heart disease

Yaghootkar, H., Lotta, L. A., Tyrrell, J., Smit, R. A. J., Jones, S. E., Donnelly, L., Beaumont, R., Campbell, A., Tuke, M. A., Hayward, C., Ruth, K. S., Padmanabhan, S., Jukema, J. W., Palmer, C. C., Hattersley, A., Freathy, R. M., Langenberg, C., Wareham, N. J., Wood, A. R., Murray, A. & 5 others, Weedon, M. N., Sattar, N., Pearson, E., Scott, R. A. & Frayling, T. M., Aug 2016, In : Diabetes. 65, 8, p. 2448-2460 13 p.

Research output: Contribution to journalArticle

Open Access
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40 Citations (Scopus)
166 Downloads (Pure)

Liothyronine use in a 17 year observational population-based study - the tears study

Leese, G. P., Soto-Pedre, E. & Donnelly, L. A., Dec 2016, In : Clinical Endocrinology. 85, 6, p. 918-925 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Mean HbA1c and mortality in diabetic individuals with heart failure: a population cohort study

Elder, D. H. J., Singh, J. S. S., Levin, D., Donnelly, L. A., Choy, A-M. J., George, J., Struthers, A. D., Doney, A. S. F. & Lang, C. C., Jan 2016, In : European Journal of Heart Failure. 18, 1, p. 94-102 9 p.

Research output: Contribution to journalArticle

Open Access
File
36 Citations (Scopus)
138 Downloads (Pure)

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

CHARGE-EchoGen Consortium, CHARGE-HF Consortium, Wellcome Trust Case Control Consortium, Ehret, G. B., Ferreira, T., Chasman, D. I., Jackson, A. U., Schmidt, E. M., Johnson, T., Thorleifsson, G., Luan, J., Donnelly, L. A., Kanoni, S., Petersen, A-K., Pihur, V., Strawbridge, R. J., Shungin, D., Hughes, M. F., Meirelles, O., Kaakinen, M. & 35 others, Bouatia-Naji, N., Kristiansson, K., Shah, S., Kleber, M. E., Guo, X., Lyytikäinen, L-P., Fava, C., Eriksson, N., Nolte, I. M., Magnusson, P. K., Salfati, E. L., Rallidis, L. S., Theusch, E., Smith, A. J. P., Folkersen, L., Witkowska, K., Pers, T. H., Joehanes, R., Kim, S. K., Lataniotis, L., Jansen, R., Johnson, A. D., Warren, H., Kim, Y. J., Zhao, W., Wu, Y., Tayo, B. O., Bochud, M., Absher, D., Connell, J. M., Doney, A. S. F., Morris, A. D., Palmer, C. N. A., Newton-Cheh, C. & Munroe, P. B., Oct 2016, In : Nature Genetics. 48, p. 1171-1184 16 p.

Research output: Contribution to journalArticle

165 Citations (Scopus)

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

METASTROKE Consortium, EchoGen Consortium, GIANT Consortium, EPIC-InterAct Consortium, LifeLines Cohort Study, Wellcome Trust Case Control Consortium, Understanding Society Scientific Group, EPIC-CVD Consortium, CHD Exome+ Consortium, T2D-Genes Consortium, GoT2D Genes Consortium, ExomeBP Consortium, The CHD Exome+ Consortium, Generation Scotland, CHARGE-Heart Failure Consortium, Surendran, P., Drenos, F., Young, R., Warren, H., Cook, J. P. & 47 others, Manning, A. K., Grarup, N., Sim, X., Barnes, D. R., Witkowska, K., Staley, J. R., Tragante, V., Tukiainen, T., Yaghootkar, H., Masca, N., Freitag, D. F., Ferreira, T., Giannakopoulou, O., Tinker, A., Harakalova, M., Mihailov, E., Liu, C., Kraja, A. T., Nielsen, S. F., Rasheed, A., Samuel, M., Zhao, W., Bonnycastle, L. L., Jackson, A. U., Narisu, N., Swift, A. J., Southam, L., Marten, J., Huyghe, J. R., Stančáková, A., Fava, C., Ohlsson, T., Matchan, A., Stirrups, K. E., Bork-Jensen, J., Gjesing, A. P., Kontto, J., Perola, M., Shaw-Hawkins, S., Donnelly, L. A., Burgess, S., Connell, J. M., Doney, A. S. F., Morris, A. D., Palmer, C. N. A., Howson, J. M. M. & Munroe, P. B., Oct 2016, In : Nature Genetics. 48, 10, p. 1151-1161 14 p.

Research output: Contribution to journalArticle

117 Citations (Scopus)