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  • James Chalmers
2017

European Respiratory Society guidelines for the management of adult bronchiectasis

Polverino, E., Goeminne, P. C., McDonnell, M. J., Aliberti, S., Marshall, S. E., Loebinger, M. R., Murris-Espin, M., Cantón, R., Torres, A., Dimakou, K., De Soyza, A., Hill, A. T., Haworth, C. S., Vendrell, M., Ringshausen, F. C., Subotic, D., Wilson, R., Vilaró, J., Stallberg, B., Welte, T. & 9 others, Rohde, G., Blasi, F., Elborn, J. S., Almagro, M., Timothy, A., Ruddy, T., Tonia, T., Rigau, D. & Chalmers, J. D., Sep 2017, In : European Respiratory Journal. 50, 3, p. 1-23 23 p., 1700629.

Research output: Contribution to journalArticle

Open Access
File
244 Citations (Scopus)
226 Downloads (Pure)

Evaluation of severity score-guided approaches to macrolide use in community-acquired pneumonia

Singanayagam, A., Aliberti, S., Cillóniz, C., Torres, A., Blasi, F. & Chalmers, J. D., Sep 2017, In : European Respiratory Journal. 50, 3, 1602306.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
183 Downloads (Pure)

High endocan levels are associated with the need for mechanical ventilation among patients with severe sepsis

Mangat, M., Amalakuhan, B., Habib, S. A., Reyes, L. F., Hinojosa, C. A., Rodriguez, A. H., Soni, N. J., Anzueto, A., Levine, S. M., Peters, J. I., Aliberti, S., Sibila, O., Rello, J., Witzenrath, M., Waterer, G. W., Martin-Loeches, I., Blanquer, J., Sanz, F., Marcos, P. J., Solé-Violán, J. & 6 others, Chalmers, J. D., Feldman, C., Wunderink, R. G., Cruz, C. S. D., Orihuela, C. J. & Restrepo, M. I., 1 Jul 2017, In : European Respiratory Journal. 50, 1, p. 1-4 4 p., 1700013.

Research output: Contribution to journalLetter

3 Citations (Scopus)

Macrolide resistance in Pseudomonas aeruginosa: implications for practice

Chalmers, J. D., May 2017, In : European Respiratory Journal. 49, 5, p. 1-3 3 p., 1700689.

Research output: Contribution to journalEditorial

3 Citations (Scopus)

Management of chronic airway diseases: What can we learn from real-life data?

Chalmers, J. D., 17 Mar 2017, In : COPD. 14, Suppl. 1, p. S1-S2 2 p.

Research output: Contribution to journalArticle

Open Access
File
195 Downloads (Pure)

Microbial Dysbiosis in Bronchiectasis and Cystic Fibrosis

Dicker, A. J. & Chalmers, J. D., Sep 2017, In : Archivos de Bronconeumologia. 53, 9, p. 471-472 2 p.

Research output: Contribution to journalEditorial

Open Access
File
1 Citation (Scopus)
208 Downloads (Pure)

Neutrophil elastase activity is associated with exacerbations and lung function decline in Bronchiectasis

Chalmers, J. D., Moffitt, K. L., Suarez-Cuartin, G., Sibila, O., Finch, S., Furrie, E., Dicker, A., Wrobel, K., Elborn, J. S., Walker, B., Martin, S. L., Marshall, S. E., Huang, J. T-J. & Fardon, T. C., 15 May 2017, In : American Journal of Respiratory and Critical Care Medicine. 195, 10, p. 1384-1393 10 p.

Research output: Contribution to journalArticle

Open Access
File
81 Citations (Scopus)
146 Downloads (Pure)

New therapies for the prevention and treatment of exacerbations of bronchiectasis

Abo-Leyah, H. & Chalmers, J. D., May 2017, In : Current Opinion in Pulmonary Medicine. 23, 3, p. 218-224 7 p.

Research output: Contribution to journalReview article

Open Access
File
6 Citations (Scopus)
181 Downloads (Pure)

Non-cystic fibrosis bronchiectasis

Finch, S., Dicker, A. & Chalmers, J., 1 Sep 2017, Acute Exacerbations of Pulmonary Diseases. Burgel, P-R., Contoli, M. & López-Campos, J. L. (eds.). European Respiratory Society, p. 38-57 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Oral versus inhaled antibiotics for non-cystic fibrosis bronchiectasis

Spencer, S., Felix, L. M., Milan, S. J., Normansell, R., Goeminne, P. C. & Chalmers, J. D., 27 Mar 2017, In : Cochrane Database of Systematic Reviews. 3, 11 p., CD012579.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Oral versus intravenous clarithromycin in moderate to severe community-acquired pneumonia: an observational study

Rae, N., Singanayagam, A., Schembri, S. & Chalmers, J. D., 5 Feb 2017, In : Pneumonia . 9, p. 1-5 5 p., 2.

Research output: Contribution to journalArticle

Open Access
File
160 Downloads (Pure)

Patient participation in ERS guidelines and research projects: the EMBARC experience

EMBARC/ELF patient advisory group, Chalmers, J. D., Timothy, A., Polverino, E., Almagro, M., Ruddy, T., Powell, P. & Boyd, J., 1 Sep 2017, In : Breathe. 13, 3, p. 194-207 14 p.

Research output: Contribution to journalReview article

Open Access
File
7 Citations (Scopus)
198 Downloads (Pure)
4 Citations (Scopus)

Pulmonary exacerbation in adults with bronchiectasis: a consensus definition for clinical research

Hill, A. T., Haworth, C. S., Aliberti, S., Barker, A., Blasi, F., Boersma, W., Chalmers, J. D., De Soyza, A., Dimakou, K., Elborn, J. S., Feldman, C., Flume, P., Goeminne, P. C., Loebinger, M. R., Menendez, R., Morgan, L., Murris-Espin, M., Polverino, E., Quittner, A., Ringshausen, F. C. & 9 others, Tino, G., Torres, A., Vendrell, M., Welte, T., Wilson, R., Wong, C., O'Donnell, A., Aksamit, T. & for the EMBARC/BRR definitions working group, 1 Jun 2017, In : European Respiratory Journal. 49, 6, 8 p., 1700051.

Research output: Contribution to journalArticle

Open Access
82 Citations (Scopus)

Raising awareness of bronchiectasis in primary care: overview of diagnosis and management strategies in adults

Chalmers, J. D. & Sethi, S., 13 Mar 2017, In : NPJ Primary Care Respiratory Medicine. 27, p. 1-9 9 p., 18.

Research output: Contribution to journalReview article

Open Access
File
16 Citations (Scopus)
160 Downloads (Pure)

Role of cephalosporins in the era of Clostridium difficile infection

Wilcox, M. H., Chalmers, J. D., Nord, C. E., Freeman, J. & Bouza, E., Jan 2017, In : Journal of Antimicrobial Chemotherapy. 72, 1, p. 1-18 18 p.

Research output: Contribution to journalArticle

Open Access
File
24 Citations (Scopus)
131 Downloads (Pure)

Severe Pneumococcal Pneumonia Causes Acute Cardiac Toxicity and Subsequent Cardiac Remodeling

Reyes, L. F., Restrepo, M. I., Hinojosa, C. A., Soni, N. J., Anzueto, A., Babu, B. L., Gonzalez-Juarbe, N., Rodriguez, A. H., Jimenez, A., Chalmers, J. D., Aliberti, S., Sibila, O., Winter, V. T., Coalson, J. J., Giavedoni, L. D., Dela Cruz, C. S., Waterer, G. W., Witzenrath, M., Suttorp, N., Dube, P. H. & 1 others, Orihuela, C. J., 1 Sep 2017, In : American Journal of Respiratory and Critical Care Medicine. 196, 5, p. 609-620 12 p.

Research output: Contribution to journalArticle

Open Access
File
39 Citations (Scopus)
303 Downloads (Pure)

Standardised classification of the aetiology of bronchiectasis using an objective algorithm

Araújo, D., Shteinberg, M., Aliberti, S., Goeminne, P. C., Hill, A. T., Fardon, T., Obradovic, D., Dimakou, K., Polverino, E., De Soyza, A., McDonnell, M. J. & Chalmers, J. D., 1 Dec 2017, In : European Respiratory Journal. 50, 6, 1701289.

Research output: Contribution to journalLetter

Open Access
File
17 Citations (Scopus)
99 Downloads (Pure)

The European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC): experiences from a successful ERS Clinical Research Collaboration

EMBARC/ELF patient advisory group, Chalmers, J. D., Crichton, M. L., Goeminne, P. C., Loebinger, M. R., Haworth, C., Almagro, M., Vendrell, M., De Soyza, A., Dhar, R., Morgan, L., Blasi, F., Aliberti, S., Boyd, J. & Polverino, E., 1 Sep 2017, In : Breathe. 13, 3, p. 180-192 13 p.

Research output: Contribution to journalReview article

Open Access
File
13 Citations (Scopus)
178 Downloads (Pure)

The heterogeneity of systemic inflammation in bronchiectasis

Saleh, A. D., Chalmers, J. D., De Soyza, A., Fardon, T. C., Koustas, S. O., Scott, J., Simpson, A. J., Brown, J. S. & Hurst, J. R., Jun 2017, In : Respiratory Medicine. 127, p. 33-39 7 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
192 Downloads (Pure)

The microbiome in respiratory medicine: current challenges and future perspectives

Faner, R., Sibila, O., Agustí, A., Bernasconi, E., Chalmers, J. D., Huffnagle, G. B., Manichanh, C., Molyneaux, P. L., Paredes, R., Pérez Brocal, V., Ponomarenko, J., Sethi, S., Dorca, J. & Monsó, E., 1 Apr 2017, In : European Respiratory Journal. 49, 4, 1602086.

Research output: Contribution to journalReview article

63 Citations (Scopus)

The past decade in bench research into pulmonary infectious diseases: What do clinicians need to know?

Finch, S., Keir, H. R., Dicker, A. J. & Chalmers, J. D., Aug 2017, In : Respirology . 22, 6, p. 1062-1072 11 p.

Research output: Contribution to journalReview article

5 Citations (Scopus)

Using Cluster Analysis of Cytokines to Identify Patterns of Inflammation in Hospitalized Patients with Community-acquired Pneumonia: A Pilot Study

Wiemken, T. L., Kelley, R., Fernandez-Botran, R., Mattingly, W. A., Arnold, F. W., Furmanek, S. P., Restrepo, M. I., Chalmers, J. D., Peyrani, P., Cavallazzi, R., Bordon, J., Aliberti, S. & Ramirez, J. A., 30 Jan 2017, In : University of Louisville Journal of Respiratory Infections. 1, 1, p. 3-11 9 p., 1.

Research output: Contribution to journalArticle

Open Access
File
186 Downloads (Pure)

Year in review 2016: Respiratory infections, acute respiratory distress syndrome, pleural diseases, lung cancer and interventional pulmonology

Restrepo, M. I., Chalmers, J. D., Song, Y., Mallow, C., Hewlett, J., Maldonado, F. & Yarmus, L., Apr 2017, In : Respirology . 22, 3, p. 602-611 10 p.

Research output: Contribution to journalReview article

Open Access
File
5 Citations (Scopus)
138 Downloads (Pure)
2016

Airway Mucin 2 is decreased in patients with severe chronic obstructive pulmonary disease with bacterial colonization

Sibila, O., Garcia-Bellmunt, L., Giner, J., Rodrigo-Troyano, A., Suarez-Cuartin, G., Torrego, A., Castillo, D., Solanes, I., Mateus, E. F., Vidal, S., Sanchez-Reus, F., Sala, E., Cosio, B. G., Restrepo, M. I., Anzueto, A., Chalmers, J. D. & Plaza, V., 1 May 2016, In : Annals of the American Thoracic Society. 13, 5, p. 636-642 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

A systematic review of the burden of vaccine preventable pneumococcal disease in UK adults

Chalmers, J. D., Dicker, A., Woodhead, M. & Madhava, H., 11 May 2016, In : BMC Pulmonary Medicine. 16, 1, p. 1-11 11 p., 77.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
203 Downloads (Pure)

Cardiovascular disease as a complication of community-acquired pneumonia

Rae, N., Finch, S. & Chalmers, J. D., May 2016, In : Current Opinion in Pulmonary Medicine. 22, 3, p. 212-218 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Characterization of bronchiectasis in the elderly

Bellelli, G., Chalmers, J. D., Sotgiu, G., Dore, S., McDonnell, M. J., Goeminne, P. C., Dimakou, K., Skrbic, D., Lombi, A., Pane, F., Obradovic, D., Fardon, T. C., Rutherford, R. M., Pesci, A. & Aliberti, S., Oct 2016, In : Respiratory Medicine. 119, p. 13-19 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
282 Downloads (Pure)

Characterizing non-tuberculous mycobacteria infection in bronchiectasis

Faverio, P., Stainer, A., Bonaiti, G., Zucchetti, S. C., Simonetta, E., Lapadula, G., Marruchella, A., Gori, A., Blasi, F., Codecasa, L., Pesci, A., Chalmers, J. D., Loebinger, M. R. & Aliberti, S., 16 Nov 2016, In : International Journal of Molecular Sciences. 17, 11, 12 p., 1913.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
136 Downloads (Pure)

Clinical phenotypes in adult patients with bronchiectasis

Aliberti, S., Lonni, S., Dore, S., McDonnell, M. J., Goeminne, P. C., Dimakou, K., Fardon, T., Rutherford, R., Pesci, A., Restrepo, M. I., Sotgiu, G. & Chalmers, J., 1 Apr 2016, In : European Respiratory Journal. 47, 4, p. 1113-1122 10 p.

Research output: Contribution to journalArticle

Open Access
File
122 Citations (Scopus)
141 Downloads (Pure)

Clinical phenotypes in bronchiectasis: Right on track to develop precision medicine in respiratory diseases

Sotgiu, G., Dore, S., Chalmers, J. D. & Aliberti, S., 1 May 2016, In : International Journal of Tuberculosis and Lung Disease. 20, 5, p. 709 1 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Community-Acquired Pneumonia: A Global Perspective

Feldman, C. & Chalmers, J. D., Dec 2016, In : Seminars in Respiratory and Critical Care Medicine. 37, 6, p. 797-798 2 p.

Research output: Contribution to journalEditorial

Open Access
File
1 Citation (Scopus)
157 Downloads (Pure)

Community-acquired pneumonia related to intracellular pathogens

Cillóniz, C., Torres, A., Niederman, M., van der Eerden, M., Chalmers, J., Welte, T. & Blasi, F., Sep 2016, In : Intensive Care Medicine. 42, 9, p. 1374-1386 13 p.

Research output: Contribution to journalArticle

Open Access
File
29 Citations (Scopus)
393 Downloads (Pure)

Comorbidities and the risk of mortality in patients with bronchiectasis: an international mulitcentre cohort study

McDonnell, M. J., Aliberti, S., Goeminne, P. C., Restrepo, M. I., Finch, S., Pesci, A., Dupont, L., Fardon, T., Wilson, R., Loebinger, M., Skrbic, D., Obradovic, D., De Soyza, A., Ward, C., Laffey, J. G., Rutherford, R. & Chalmers, J., Dec 2016, In : The Lancet Respiratory Medicine. 4, 12, p. 969-979 11 p.

Research output: Contribution to journalArticle

Open Access
File
84 Citations (Scopus)
155 Downloads (Pure)

Corticosteroids for community-acquired pneumonia: a critical view of the evidence

Chalmers, J. D., 1 Oct 2016, In : European Respiratory Journal. 48, 4, p. 984-986 3 p.

Research output: Contribution to journalEditorial

10 Citations (Scopus)

Diagnostic challenges of bronchiectasis

Suarez-Cuartin, G., Chalmers, J. D. & Sibila, O., 1 Jul 2016, In : Respiratory Medicine. 116, p. 70-77 8 p.

Research output: Contribution to journalReview article

Open Access
File
15 Citations (Scopus)
172 Downloads (Pure)

Empirical coverage of methicillin-resistant Staphylococcus aureus in community-acquired pneumonia: those who do not remember the past are doomed to repeat it

Chalmers, J. D., Reyes, L. F., Aliberti, S. & Restrepo, M. I., 15 Oct 2016, In : Clinical Infectious Diseases. 63, 8, p. 1145-1146 1 p.

Research output: Contribution to journalLetter

8 Citations (Scopus)
16 Downloads (Pure)

Endothelial adhesion molecules and multiple organ failure in patients with severe sepsis

Amalakuhan, B., Habib, S. A., Mangat, M., Reyes, L. F., Rodriguez, A. H., Hinojosa, C. A., Soni, N. J., Gilley, R. P., Bustamante, C. A., Anzueto, A., Levine, S. M., Peters, J. I., Aliberti, S., Sibila, O., Chalmers, J. D., Torres, A., Waterer, G. W., Martin-Loeches, I., Bordon, J., Blanquer, J. & 15 others, Sanz, F., Marcos, P. J., Rello, J., Ramirez, J., Solé-Violán, J., Luna, C. M., Feldman, C., Witzenrath, M., Wunderink, R. G., Stolz, D., Wiemken, T. L., Shindo, Y., Dela Cruz, C. S., Orihuela, C. J. & Restrepo, M. I., Dec 2016, In : Cytokine. 88, p. 267-273 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
125 Downloads (Pure)

Evaluation of serum inflammatory biomarkers as predictors of treatment outcome in pulmonary tuberculosis

Singanayagam, A., Manalan, K., Connell, D. W., Chalmers, J. D., Sridhar, S., Ritchie, A. I., Lalvani, A., Wickremasinghe, M. & Kon, O. M., 1 Dec 2016, In : International Journal of Tuberculosis and Lung Disease. 20, 12, p. 1653-1660 8 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
146 Downloads (Pure)

Global impact of bronchiectasis and cystic fibrosis

Redondo, M., Keyt, H., Dhar, R. & Chalmers, J. D., 1 Sep 2016, In : Breathe. 12, 3, p. 222-235 14 p.

Research output: Contribution to journalReview article

Open Access
File
18 Citations (Scopus)
174 Downloads (Pure)

Macrolide antibiotics for non-cystic fibrosis bronchiectasis

Kelly, C., Evans, D. J., Chalmers, J. D., Crossingham, I., Spencer, S., Relph, N., Felix, L. M. & Milan, S. J., 21 Oct 2016, In : Cochrane Database of Systematic Reviews. 10, p. 1-11 13 p., CD012406.

Research output: Contribution to journalReview article

Open Access
File
6 Citations (Scopus)
147 Downloads (Pure)

Microbial dysbiosis after lung transplantation

Chalmers, J. D., 15 Nov 2016, In : American Journal of Respiratory and Critical Care Medicine. 194, 10, p. 1184-1186 3 p.

Research output: Contribution to journalEditorial

3 Citations (Scopus)

Multidimensional severity assessment in bronchiectasis: An analysis of 7 European cohorts.

McDonnell, M. J., Alberti, S., Goeminne, P. C., Dimakou, K., Davidson, J., Ward, C., LAffey, JG., Finch, S., Pesci, A., Dupont, LJ., Fardon, T. C., Skrbic, D., Obradovic, D., Cowman, S., Loebinger, M. R., Rutherford, RM., De Soyza, A. & Chalmers, J. D., Dec 2016, In : Thorax. 71, 12, p. 1110-1118 9 p.

Research output: Contribution to journalArticle

Open Access
File
70 Citations (Scopus)
150 Downloads (Pure)

Pseudomonas aeruginosa resistance patterns and clinical outcomes in hospitalized exacerbations of COPD

Rodrigo-Troyano, A., Suarez-Cuartin, G., Peiró, M., Barril, S., Castillo, D., Sanchez-Reus, F., Plaza, V., Restrepo, M. I., Chalmers, J. D. & Sibila, O., Oct 2016, In : Respirology . 21, 7, p. 1235-1242 8 p.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
164 Downloads (Pure)

Quality standards for the management of bronchiectasis in Italy: a national audit

SIP Bronchiectasis Audit Working Group, Aliberti, S., Hill, A. T., Mantero, M., Battaglia, S., Centanni, S., Lo Cicero, S., Lacedonia, D., Saetta, M., Chalmers, J. D. & Blasi, F., 30 Jun 2016, In : European Respiratory Journal. 48, 1, p. 244-248 5 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Reply: Measuring airway Mucin 2 in patients with severe Chronic Obstructive Pulmonary Disease with bacterial colonization

Sibila, O., Mateus, E. F., Restrepo, M. I., Chalmers, J. D. & Vidal, S., 1 Nov 2016, In : Annals of the American Thoracic Society. 13, 11, p. 2104-2105 2 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Research priorities in bronchiectasis: a consensus statement from the EMBARC Clinical Research Collaboration

Aliberti, S., Masefield, S., Polverino, E., De Soyza, A., Loebinger, M. R., Menendez, R., Ringshausen, F. C., Vendrell, M., Powell, P., Chalmers, J. D. &  on behalf of the EMBARC Study Group, 1 Sep 2016, In : European Respiratory Journal. 48, 3, p. 632-647 16 p.

Research output: Contribution to journalArticle

Open Access
File
86 Citations (Scopus)
220 Downloads (Pure)

Review of the British Thoracic Society Winter Meeting 2015, 2-4 December, London, UK

José, R. J., Chalmers, J. D., Greening, N. J. & Janes, S. M., Jun 2016, In : Thorax. 71, 6, p. 555-559 5 p.

Research output: Contribution to journalArticle

Open Access
File
213 Downloads (Pure)

Risk factors for Clostridium difficile infection in hospitalized patients with community-acquired pneumonia

Chalmers, J. D., Akram, A. R., Singanayagam, A., Wilcox, M. H. & Hill, A. T., Jul 2016, In : Journal of Infection. 73, 1, p. 45-53 9 p.

Research output: Contribution to journalArticle

Open Access
File
29 Citations (Scopus)
235 Downloads (Pure)

The EMBARC European Bronchiectasis Registry: protocol for an international observational study

Chalmers, J. D., Aliberti, S., Polverino, E., Vendrell, M., Crichton, M., Loebinger, M., Dimakou, K., Clifton, I., van der Eerden, M., Rohde, G., Murris-Espin, M., Masefield, S., Gerada, E., Shteinberg, M., Ringshausen, F., Haworth, C., Boersma, W., Rademacher, J., Hill, A. T., Aksamit, T. & 17 others, O'Donnell, A., Morgan, L., Milenkovic, B., Tramma, L., Neves, J., Menendez, R., Paggiaro, P., Botnaru, V., Skrgat, S., Wilson, R., Goeminne, P., De Soyza, A., Welte, T., Torres, A., Elborn, J. S., Blasi, F. & on behalf of EMBARC, Jan 2016, In : ERJ Open Research. 2, 1, p. 1-9 9 p., 00081-2015.

Research output: Contribution to journalArticle

Open Access
File
82 Citations (Scopus)
165 Downloads (Pure)