Find Research Outputs

Search results

• 2019

  Addendum to: Relative and Absolute Risk of Tendon Rupture with Fluoroquinolone and Concomitant Fluoroquinolone/Corticosteroid Therapy: Population-Based Nested Case-Control Study

  Morales, D. R., Flynn, R. & Kurz, X., Jun 2019, In: Clinical Drug Investigation. 39, 6, p. 591-594 4 p.

  Research output: Contribution to journal › Letter › peer-review
  3 Citations (Scopus)

• A European multicentre drug utilisation study of the impact of regulatory measures on prescribing of codeine for pain in children

  Hedenmalm, K., Blake, K., Donegan, K., Macia, M. A., Gil, M., Williams, J., Montero, D., Candore, G., Morales, D., Kurz, X. & Arlett, P., Aug 2019, In: Pharmacoepidemiology and Drug Safety. 28, 8, p. 1086-1096 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Drug Utilization
  • Codeine
  • Germany
  • Adenoidectomy
  • Spain
  6 Citations (Scopus)

  109 Downloads (Pure)

• Association Between Peripheral Neuropathy and Exposure to Oral Fluoroquinolone or Amoxicillin-Clavulanate Therapy

  Morales, D., Pacurariu, A., Slattery, J., Pinheiro, L., McGettigan, P. & Kurz, X., 1 Jul 2019, In: JAMA Neurology. 76, 7, p. 827-833 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Clavulanic Acid
  • Fluoroquinolones
  • Amoxicillin
  • Peripheral Nervous System Diseases
  • Anti-Bacterial Agents
  15 Citations (Scopus)

• Correction to: Relative and Absolute Risk of Tendon Rupture with Fluoroquinolone and Concomitant Fluoroquinolone/Corticosteroid Therapy: Population-Based Nested Case-Control Study

  Morales, D. R., Slattery, J., Pacurariu, A., Pinheiro, L., McGettigan, P. & Kurz, X., Feb 2019, In: Clinical Drug Investigation. 39, 2, p. 215 1 p.

  Research output: Contribution to journal › Article

  Open Access

  File

  • Fluoroquinolones
  • Tendons
  • Rupture
  • Case-Control Studies
  • Adrenal Cortex Hormones
  1 Citation (Scopus)

  132 Downloads (Pure)

• Effect of withdrawal of fusafungine from the market on prescribing of antibiotics and other alternative treatments in Germany: a pharmacovigilance impact study

  Hedenmalm, K., Kurz, X. & Morales, D., Jul 2019, In: European Journal of Clinical Pharmacology. 75, 7, p. 979-984 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • fusafungin
  • Product Recalls and Withdrawals
  • Pharmacovigilance
  • Germany
  • Anti-Bacterial Agents
  4 Citations (Scopus)

  138 Downloads (Pure)

• Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial

  Dennis, M., Mead, G., Forbes, J., Graham, C., Hackett, M., Hankey, G. J., House, A., Lewis, S., Lundström, E., Sandercock, P., Innes, K., Williams, C., Drever, J., Mcgrath, A., Deary, A., Fraser, R., Anderson, R., Walker, P., Perry, D., Mcgill, C. & 31 others, Buchanan, D., Chun, Y., Dinsmore, L., Maschauer, E., Barugh, A., Mikhail, S., Blair, G., Hoeritzauer, I., Scott, M., Fraser, G., Burgess, D., Morales, D., Sullivan, F., Ross, F., Burgess, L., Young, R., Bokhari, M., Bruce, D., Potter, A., Evans, R., Smith, A., Johnston, S., Ross, S., Stirling, M., Simpson, J., Wright, A., Raza, S. A., Bell, A., Kumar, P., Thompson, A. & Khan, M. F., 19 Jan 2019, In: The Lancet. 393, 10168, p. 265-274 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Fluoxetine
  • Stroke
  • Randomized Controlled Trials
  • Placebos
  • Bone Fractures
  85 Citations (Scopus)

  150 Downloads (Pure)

• Facial palsy: when and why to refer for specialist care

  Butler, D. P., Morales, D. R., Johnson, K. & Nduka, C., Nov 2019, In: British Journal of General Practice. 69, 688, p. 579-580 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Facial Paralysis
  • Secondary Care
  • Primary Health Care
  • Facial Muscles
  • Facial Expression
  2 Citations (Scopus)

  13 Downloads (Pure)

• How to validate a diagnosis recorded in electronic health records

  Nissen, F., Quint, J. K., Morales, D. R. & Douglas, I. J., 1 Mar 2019, In: Breathe. 15, 1, p. 64-68 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Electronic Health Records
  • Databases
  3 Citations (Scopus)

  131 Downloads (Pure)

• Opioid use, postoperative complications, and implant survival after unicompartmental versus total knee replacement: a population-based network study

  Burn, E., Weaver, J., Morales, D., Prats-Uribe, A., Delmestri, A., Strauss, V. Y., He, Y., Robinson, D. E., Pinedo-Villanueva, R., Kolovos, S., Duarte-Salles, T., Sproviero, W., Yu, D., Van Speybroeck, M., Williams, R., John, L. H., Hughes, N., Sena, A. G., Costello, R., Birlie, B. & 6 others, Culliford, D., O'Leary, C., Morgan, H., Burkard, T., Prieto-Alhambra, D. & Ryan, P., Dec 2019, In: The Lancet Rheumatology. 1, 4, p. e229-e236 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Knee Replacement Arthroplasties
  • Opioid Analgesics
  • Postoperative Complications
  • Survival
  • Population
  5 Citations (Scopus)

  65 Downloads (Pure)

• Prescribing patterns of tramadol in adults in IMS® primary care databases in France and Germany between 1 January 2006 and 30 June 2016

  Hedenmalm, K., Slattery, J., Skibicka-stepien, I., Kurz, X. & Morales, D., May 2019, In: European Journal of Clinical Pharmacology. 75, 5, p. 707-716 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Tramadol
  • France
  • Germany
  • Primary Health Care
  • Databases
  3 Citations (Scopus)

  137 Downloads (Pure)

• Relative and Absolute Risk of Tendon Rupture with Fluoroquinolone and Concomitant Fluoroquinolone/Corticosteroid Therapy: Population-Based Nested Case-Control Study

  Morales, D. R., Slattery, J., Pacurariu, A., Pinheiro, L., McGettigan, P. & Kurz, X., Feb 2019, In: Clinical Drug Investigation. 39, 2, p. 205-213 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Fluoroquinolones
  • Tendons
  • Rupture
  • Case-Control Studies
  • Adrenal Cortex Hormones
  16 Citations (Scopus)

  67 Downloads (Pure)
• 2018

  Antidepressant use during pregnancy and risk of autism spectrum disorder and attention deficit hyperactivity disorder: systematic review of observational studies and methodological considerations

  Morales, D. R., Slattery, J., Evans, S. & Kurz, X., 15 Jan 2018, In: BMC Medicine. 16, 1, p. 1-14 14 p., 6.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Autism Spectrum Disorder
  • Attention Deficit Disorder with Hyperactivity
  • Antidepressive Agents
  • Observational Studies
  • Systematic Reviews
  33 Citations (Scopus)

  155 Downloads (Pure)

• Challenges in interpreting trends in testing for α₁-antitrypsin deficiency in COPD patients from UK primary care

  Morales, D. R., 22 Dec 2018, In: The European respiratory journal. 52, 6, 1801986.

  Research output: Contribution to journal › Letter › peer-review

  • Chronic Obstructive Pulmonary Disease
  • Primary Health Care
  • Delivery of Health Care
  • Population

• Cohort Study of Psychiatric Adverse Events Following Exposure to Levonorgestrel-Containing Intrauterine Devices in UK General Practice

  Slattery, J., Morales, D., Pinheiro, L. & Kurz, X., Oct 2018, In: Drug Safety. 41, 10, p. 951-958 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Psychiatry
  • Levonorgestrel
  • Intrauterine Devices
  • General Practice
  • Hazards
  7 Citations (Scopus)

  436 Downloads (Pure)

• Concomitant diagnosis of asthma and COPD: a quantitative study in UK primary care

  Nissen, F., Morales, D. R., Mullerova, H., Smeeth, L., Douglas, I. J. & Quint, J. K., Nov 2018, In: British Journal of General Practice. 68, 676, p. e775-e782 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Chronic Obstructive Pulmonary Disease
  • Primary Health Care
  • Asthma
  • Confidence Intervals
  • Validation Studies
  12 Citations (Scopus)

  159 Downloads (Pure)

• Electronic healthcare databases in Europe: descriptive analysis of characteristics and potential for use in medicines regulation

  Pacurariu, A., Plueschke, K., McGettigan, P., Morales, D., Slattery, J., Vogl, D., Goedecke, T., Kurz, X. & Cave, A., 5 Sep 2018, In: BMJ Open. 8, 9, p. e023090 9 p., e023090.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Databases
  • Delivery of Health Care
  • Information Storage and Retrieval
  • Pharmacoepidemiology
  • Pharmacovigilance
  12 Citations (Scopus)

  160 Downloads (Pure)

• External validation of ADO, DOSE, COTE and CODEX at predicting death in primary care patients with COPD using standard and machine learning approaches

  Morales, D., Flynn, R., Zhang, J., Trucco, E. & Quint, J. K., 1 May 2018, In: Respiratory Medicine. 138, p. 150-155 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Machine Learning
  • Dyspnea
  • Chronic Obstructive Pulmonary Disease
  • Comorbidity
  • Primary Health Care
  7 Citations (Scopus)

  277 Downloads (Pure)

• Indications for Systemic Fluoroquinolone Therapy in Europe and Prevalence of Primary-Care Prescribing in France, Germany and the UK: Descriptive Population-Based Study

  Morales, D. R., Slattery, J., Pinheiro, L., Kurz, X. & Hedenmalm, K., Aug 2018, In: Clinical Drug Investigation. 38, 10, p. 927-933 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Fluoroquinolones
  • France
  • Germany
  • Primary Health Care
  • Sinusitis
  6 Citations (Scopus)

  121 Downloads (Pure)

• Low uptake of palliative care for COPD patients within primary care in the UK

  Bloom, C. I., Slaich, B., Morales, D. R., Smeeth, L., Stone, P. & Quint, J. K., Feb 2018, In: European Respiratory Journal. 51, 2, p. 1-10 10 p., 1701879.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Palliative Care
  • Chronic Obstructive Pulmonary Disease
  • Primary Health Care
  • Lung Neoplasms
  • Dyspnea
  23 Citations (Scopus)

  140 Downloads (Pure)

• Response to 'Comment on 'Measuring the impact of medicines regulatory interventions - systematic review and methodological considerations' by Goedecke et al.'

  Goedecke, T., Morales, D. R., Pacurariu, A. & Kurz, X., Sep 2018, In: British Journal of Clinical Pharmacology. 84, 9, p. 2169-2170 2 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  1 Citation (Scopus)
• 2017

  Application of real-time global media monitoring and ‘derived questions’ for enhancing communication by regulatory bodies: the case of human papillomavirus vaccines

  Bahri, P., Fogd, J., Morales, D. & Kurz, X., 2 May 2017, In: BMC Medicine. 15, p. 1-13 13 p., 91.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Postural Orthostatic Tachycardia Syndrome
  • Papillomavirus Vaccines
  • Complex Regional Pain Syndromes
  • European Union
  • Vaccines
  13 Citations (Scopus)

  196 Downloads (Pure)

• Comorbidities in adults with asthma: population-based cross-sectional analysis of 1.4 million adults in Scotland

  Weatherburn, C. J., Guthrie, B., Mercer, S. W. & Morales, D. R., 28 Sep 2017, In: Clinical and Experimental Allergy. 47, 10, p. 1246-1252 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Scotland
  • Comorbidity
  • Asthma
  • Cross-Sectional Studies
  • Population
  27 Citations (Scopus)

  152 Downloads (Pure)

• Measuring the impact of medicines regulatory interventions - systematic review and methodological considerations

  Goedecke, T., Morales, D., Pacurariu, A. & Kurz, X., 20 Dec 2017, In: British Journal of Clinical Pharmacology. 84, p. 419-433 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Systematic Reviews
  • Communication
  • Drug Labeling
  • Public Health
  • Interrupted Time Series Analysis
  33 Citations (Scopus)

  154 Downloads (Pure)

• Off-label prescribing of antidepressants

  Morales, D. R. & Guthrie, B., 21 Feb 2017, In: BMJ. 356, 2 p., j849.

  Research output: Contribution to journal › Editorial

  Open Access

  File
  2 Citations (Scopus)

  218 Downloads (Pure)

• Respiratory effect of beta-blockers in people with asthma and cardiovascular disease: population-based nested case control study

  Morales, D. R., Lipworth, B. J., Donnan, P. T., Jackson, C. & Guthrie, B., 27 Jan 2017, In: BMC Medicine. 15, 9 p., 18.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Case-Control Studies
  • Asthma
  • Cardiovascular Diseases
  • Population
  • Incidence
  31 Citations (Scopus)

  318 Downloads (Pure)

• Validation of asthma recording in the Clinical Practice Research Datalink (CPRD)

  Nissen, F., Morales, D. R., Mullerova, H., Smeeth, L., Douglas, I. J. & Quint, J. K., 1 Aug 2017, In: BMJ Open. 7, 8, p. 1-9 9 p., e017474.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Asthma
  • Advisory Committees
  • Prescriptions
  • Primary Health Care
  • Peer Review
  32 Citations (Scopus)

  172 Downloads (Pure)
• 2016

  Accounting for multimorbidity in pay for performance: a modelling study using UK Quality and Outcomes Framework data

  Ruscitto, A., Mercer, S. W., Morales, D. & Guthrie, B., 5 Jul 2016, In: British Journal of General Practice. 66, 649, p. e561-e567 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Incentive Reimbursement
  • Multimorbidity
  • Human Influenza
  • Immunization
  • Blood Pressure
  2 Citations (Scopus)

• Respiratory effect of beta-blocker eye drops in asthma: population-based study and meta-analysis of clinical trials

  Morales, D. R., Dreischulte, T., Lipworth, B. J., Donnan, P. T., Jackson, C. & Guthrie, B., 8 Aug 2016, In: British Journal of Clinical Pharmacology. 82, 3, p. 814-822 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ophthalmic Solutions
  • Asthma
  • Meta-Analysis
  • Clinical Trials
  • Ocular Hypertension
  24 Citations (Scopus)

  189 Downloads (Pure)