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  • James Chalmers
2016

Airway Mucin 2 is decreased in patients with severe chronic obstructive pulmonary disease with bacterial colonization

Sibila, O., Garcia-Bellmunt, L., Giner, J., Rodrigo-Troyano, A., Suarez-Cuartin, G., Torrego, A., Castillo, D., Solanes, I., Mateus, E. F., Vidal, S., Sanchez-Reus, F., Sala, E., Cosio, B. G., Restrepo, M. I., Anzueto, A., Chalmers, J. D. & Plaza, V., 1 May 2016, In : Annals of the American Thoracic Society. 13, 5, p. 636-642 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

A systematic review of the burden of vaccine preventable pneumococcal disease in UK adults

Chalmers, J. D., Dicker, A., Woodhead, M. & Madhava, H., 11 May 2016, In : BMC Pulmonary Medicine. 16, 1, p. 1-11 11 p., 77.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
197 Downloads (Pure)

Cardiovascular disease as a complication of community-acquired pneumonia

Rae, N., Finch, S. & Chalmers, J. D., May 2016, In : Current Opinion in Pulmonary Medicine. 22, 3, p. 212-218 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Characterization of bronchiectasis in the elderly

Bellelli, G., Chalmers, J. D., Sotgiu, G., Dore, S., McDonnell, M. J., Goeminne, P. C., Dimakou, K., Skrbic, D., Lombi, A., Pane, F., Obradovic, D., Fardon, T. C., Rutherford, R. M., Pesci, A. & Aliberti, S., Oct 2016, In : Respiratory Medicine. 119, p. 13-19 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
275 Downloads (Pure)

Characterizing non-tuberculous mycobacteria infection in bronchiectasis

Faverio, P., Stainer, A., Bonaiti, G., Zucchetti, S. C., Simonetta, E., Lapadula, G., Marruchella, A., Gori, A., Blasi, F., Codecasa, L., Pesci, A., Chalmers, J. D., Loebinger, M. R. & Aliberti, S., 16 Nov 2016, In : International Journal of Molecular Sciences. 17, 11, 12 p., 1913.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
132 Downloads (Pure)

Clinical phenotypes in adult patients with bronchiectasis

Aliberti, S., Lonni, S., Dore, S., McDonnell, M. J., Goeminne, P. C., Dimakou, K., Fardon, T., Rutherford, R., Pesci, A., Restrepo, M. I., Sotgiu, G. & Chalmers, J., 1 Apr 2016, In : European Respiratory Journal. 47, 4, p. 1113-1122 10 p.

Research output: Contribution to journalArticle

Open Access
File
122 Citations (Scopus)
137 Downloads (Pure)

Clinical phenotypes in bronchiectasis: Right on track to develop precision medicine in respiratory diseases

Sotgiu, G., Dore, S., Chalmers, J. D. & Aliberti, S., 1 May 2016, In : International Journal of Tuberculosis and Lung Disease. 20, 5, p. 709 1 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Community-Acquired Pneumonia: A Global Perspective

Feldman, C. & Chalmers, J. D., Dec 2016, In : Seminars in Respiratory and Critical Care Medicine. 37, 6, p. 797-798 2 p.

Research output: Contribution to journalEditorial

Open Access
File
1 Citation (Scopus)
148 Downloads (Pure)

Community-acquired pneumonia related to intracellular pathogens

Cillóniz, C., Torres, A., Niederman, M., van der Eerden, M., Chalmers, J., Welte, T. & Blasi, F., Sep 2016, In : Intensive Care Medicine. 42, 9, p. 1374-1386 13 p.

Research output: Contribution to journalArticle

Open Access
File
29 Citations (Scopus)
379 Downloads (Pure)

Comorbidities and the risk of mortality in patients with bronchiectasis: an international mulitcentre cohort study

McDonnell, M. J., Aliberti, S., Goeminne, P. C., Restrepo, M. I., Finch, S., Pesci, A., Dupont, L., Fardon, T., Wilson, R., Loebinger, M., Skrbic, D., Obradovic, D., De Soyza, A., Ward, C., Laffey, J. G., Rutherford, R. & Chalmers, J., Dec 2016, In : The Lancet Respiratory Medicine. 4, 12, p. 969-979 11 p.

Research output: Contribution to journalArticle

Open Access
File
84 Citations (Scopus)
153 Downloads (Pure)

Corticosteroids for community-acquired pneumonia: a critical view of the evidence

Chalmers, J. D., 1 Oct 2016, In : European Respiratory Journal. 48, 4, p. 984-986 3 p.

Research output: Contribution to journalEditorial

10 Citations (Scopus)

Diagnostic challenges of bronchiectasis

Suarez-Cuartin, G., Chalmers, J. D. & Sibila, O., 1 Jul 2016, In : Respiratory Medicine. 116, p. 70-77 8 p.

Research output: Contribution to journalReview article

Open Access
File
15 Citations (Scopus)
168 Downloads (Pure)

Empirical coverage of methicillin-resistant Staphylococcus aureus in community-acquired pneumonia: those who do not remember the past are doomed to repeat it

Chalmers, J. D., Reyes, L. F., Aliberti, S. & Restrepo, M. I., 15 Oct 2016, In : Clinical Infectious Diseases. 63, 8, p. 1145-1146 1 p.

Research output: Contribution to journalLetter

8 Citations (Scopus)
16 Downloads (Pure)

Endothelial adhesion molecules and multiple organ failure in patients with severe sepsis

Amalakuhan, B., Habib, S. A., Mangat, M., Reyes, L. F., Rodriguez, A. H., Hinojosa, C. A., Soni, N. J., Gilley, R. P., Bustamante, C. A., Anzueto, A., Levine, S. M., Peters, J. I., Aliberti, S., Sibila, O., Chalmers, J. D., Torres, A., Waterer, G. W., Martin-Loeches, I., Bordon, J., Blanquer, J. & 15 others, Sanz, F., Marcos, P. J., Rello, J., Ramirez, J., Solé-Violán, J., Luna, C. M., Feldman, C., Witzenrath, M., Wunderink, R. G., Stolz, D., Wiemken, T. L., Shindo, Y., Dela Cruz, C. S., Orihuela, C. J. & Restrepo, M. I., Dec 2016, In : Cytokine. 88, p. 267-273 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
122 Downloads (Pure)

Evaluation of serum inflammatory biomarkers as predictors of treatment outcome in pulmonary tuberculosis

Singanayagam, A., Manalan, K., Connell, D. W., Chalmers, J. D., Sridhar, S., Ritchie, A. I., Lalvani, A., Wickremasinghe, M. & Kon, O. M., 1 Dec 2016, In : International Journal of Tuberculosis and Lung Disease. 20, 12, p. 1653-1660 8 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
143 Downloads (Pure)

Global impact of bronchiectasis and cystic fibrosis

Redondo, M., Keyt, H., Dhar, R. & Chalmers, J. D., 1 Sep 2016, In : Breathe. 12, 3, p. 222-235 14 p.

Research output: Contribution to journalReview article

Open Access
File
18 Citations (Scopus)
168 Downloads (Pure)

Macrolide antibiotics for non-cystic fibrosis bronchiectasis

Kelly, C., Evans, D. J., Chalmers, J. D., Crossingham, I., Spencer, S., Relph, N., Felix, L. M. & Milan, S. J., 21 Oct 2016, In : Cochrane Database of Systematic Reviews. 10, p. 1-11 13 p., CD012406.

Research output: Contribution to journalReview article

Open Access
File
6 Citations (Scopus)
144 Downloads (Pure)

Microbial dysbiosis after lung transplantation

Chalmers, J. D., 15 Nov 2016, In : American Journal of Respiratory and Critical Care Medicine. 194, 10, p. 1184-1186 3 p.

Research output: Contribution to journalEditorial

3 Citations (Scopus)

Multidimensional severity assessment in bronchiectasis: An analysis of 7 European cohorts.

McDonnell, M. J., Alberti, S., Goeminne, P. C., Dimakou, K., Davidson, J., Ward, C., LAffey, JG., Finch, S., Pesci, A., Dupont, LJ., Fardon, T. C., Skrbic, D., Obradovic, D., Cowman, S., Loebinger, M. R., Rutherford, RM., De Soyza, A. & Chalmers, J. D., Dec 2016, In : Thorax. 71, 12, p. 1110-1118 9 p.

Research output: Contribution to journalArticle

Open Access
File
70 Citations (Scopus)
149 Downloads (Pure)

Pseudomonas aeruginosa resistance patterns and clinical outcomes in hospitalized exacerbations of COPD

Rodrigo-Troyano, A., Suarez-Cuartin, G., Peiró, M., Barril, S., Castillo, D., Sanchez-Reus, F., Plaza, V., Restrepo, M. I., Chalmers, J. D. & Sibila, O., Oct 2016, In : Respirology . 21, 7, p. 1235-1242 8 p.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
161 Downloads (Pure)

Quality standards for the management of bronchiectasis in Italy: a national audit

SIP Bronchiectasis Audit Working Group, Aliberti, S., Hill, A. T., Mantero, M., Battaglia, S., Centanni, S., Lo Cicero, S., Lacedonia, D., Saetta, M., Chalmers, J. D. & Blasi, F., 30 Jun 2016, In : European Respiratory Journal. 48, 1, p. 244-248 5 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Reply: Measuring airway Mucin 2 in patients with severe Chronic Obstructive Pulmonary Disease with bacterial colonization

Sibila, O., Mateus, E. F., Restrepo, M. I., Chalmers, J. D. & Vidal, S., 1 Nov 2016, In : Annals of the American Thoracic Society. 13, 11, p. 2104-2105 2 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Research priorities in bronchiectasis: a consensus statement from the EMBARC Clinical Research Collaboration

Aliberti, S., Masefield, S., Polverino, E., De Soyza, A., Loebinger, M. R., Menendez, R., Ringshausen, F. C., Vendrell, M., Powell, P., Chalmers, J. D. &  on behalf of the EMBARC Study Group, 1 Sep 2016, In : European Respiratory Journal. 48, 3, p. 632-647 16 p.

Research output: Contribution to journalArticle

Open Access
File
84 Citations (Scopus)
214 Downloads (Pure)

Review of the British Thoracic Society Winter Meeting 2015, 2-4 December, London, UK

José, R. J., Chalmers, J. D., Greening, N. J. & Janes, S. M., Jun 2016, In : Thorax. 71, 6, p. 555-559 5 p.

Research output: Contribution to journalArticle

Open Access
File
209 Downloads (Pure)

Risk factors for Clostridium difficile infection in hospitalized patients with community-acquired pneumonia

Chalmers, J. D., Akram, A. R., Singanayagam, A., Wilcox, M. H. & Hill, A. T., Jul 2016, In : Journal of Infection. 73, 1, p. 45-53 9 p.

Research output: Contribution to journalArticle

Open Access
File
28 Citations (Scopus)
230 Downloads (Pure)

The EMBARC European Bronchiectasis Registry: protocol for an international observational study

Chalmers, J. D., Aliberti, S., Polverino, E., Vendrell, M., Crichton, M., Loebinger, M., Dimakou, K., Clifton, I., van der Eerden, M., Rohde, G., Murris-Espin, M., Masefield, S., Gerada, E., Shteinberg, M., Ringshausen, F., Haworth, C., Boersma, W., Rademacher, J., Hill, A. T., Aksamit, T. & 17 others, O'Donnell, A., Morgan, L., Milenkovic, B., Tramma, L., Neves, J., Menendez, R., Paggiaro, P., Botnaru, V., Skrgat, S., Wilson, R., Goeminne, P., De Soyza, A., Welte, T., Torres, A., Elborn, J. S., Blasi, F. & on behalf of EMBARC, Jan 2016, In : ERJ Open Research. 2, 1, p. 1-9 9 p., 00081-2015.

Research output: Contribution to journalArticle

Open Access
File
80 Citations (Scopus)
162 Downloads (Pure)

The generalizability of bronchiectasis randomized controlled trials: a multicentre cohort study

Chalmers, J. D., McDonnell, M. J., Rutherford, R., Davidson, J., Finch, S., Crichton, M., Dupont, L., Hill, A. T., Fardon, T. C., De Soyza, A., Aliberti, S. & Goeminne, P., Mar 2016, In : Respiratory Medicine. 112, p. 51-58 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

The Modern Diagnostic Approach to Community-Acquired Pneumonia in Adults

Chalmers, J. D., Dec 2016, In : Seminars in Respiratory and Critical Care Medicine. 37, 6, p. 876-885 10 p.

Research output: Contribution to journalReview article

Open Access
File
3 Citations (Scopus)
211 Downloads (Pure)

The type VII secretion system of Staphylococcus aureus secretes a nuclease toxin that targets competitor bacteria

Cao, Z., Kneuper, H., Casabona, M. G., Chalmers, J. D. & Palmer, T., 10 Oct 2016, In : Nature Microbiology. 2, p. 1-11 11 p., 16183.

Research output: Contribution to journalArticle

Open Access
File
69 Citations (Scopus)
289 Downloads (Pure)
2017

10 years since TORCH: shining a new light on the risks of inhaled corticosteroids in COPD

Chalmers, J. D. & Keir, H. R., 1 Sep 2017, In : European Respiratory Journal. 50, 3, 5 p., 1701582.

Research output: Contribution to journalEditorial

3 Citations (Scopus)

Additional important research priorities for bronchiectasis in China

Aliberti, S., Dhar, R., Aksamit, T. R., Morgan, L. & Chalmers, J. D., 1 Jan 2017, In : European Respiratory Journal. 49, 1, 1602317.

Research output: Contribution to journalLetter

Open Access
File
154 Downloads (Pure)

A new free-cost e-service supporting clinicians to manage their difficult-to-treat tuberculosis cases: The European Respiratory Society-World Health Organization tuberculosis Consilium

D'Ambrosio, L., Tadolini, M., Centis, R., Chalmers, J. D. & Migliori, G. B., 27 Jul 2017, In : Indian Journal of Medical Research. 145, 3, p. 261-263 3 p.

Research output: Contribution to journalEditorial

Open Access
File
20 Downloads (Pure)

Anti-Pseudomonas aeruginosa IgG antibodies and chronic airway infection in bronchiectasis

Suarez-Cuartin, G., Smith, A., Abo-Leyah, H., Rodrigo-Troyano, A., Perea, L., Vidal, S., Plaza, V., Fardon, T. C., Sibila, O. & Chalmers, J. D., Jul 2017, In : Respiratory Medicine. 128, p. 1-6 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

A randomised control trial of atorvastatin in bronchiectasis patients infected with Pseudomonas aeruginosa- a proof of concept study

Bedi, P., Chalmers, J. D., Graham, C., Clarke, A., Donaldson, S., Doherty, C. J., Govan, J. R. W., Davidson, D. J., Rossi, A. G. & Hill, A. T., Aug 2017, In : Chest. 152, 2, p. 368-378 11 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
144 Downloads (Pure)

Bronchiectasis: Phenotyping a Complex Disease

Chalmers, J. D., 17 Mar 2017, In : COPD. 14, Suppl.1, p. S12-S18 7 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
150 Downloads (Pure)

Bronchiectasis and COPD Overlap: A Case of Mistaken Identity?

Chalmers, J. D., Jun 2017, In : Chest. 151, 6, p. 1204-1206 3 p.

Research output: Contribution to journalEditorial

11 Citations (Scopus)

Bronchiectasis Management: The State of the Union

Chalmers, J. D. & Restrepo, M. I., Dec 2017, In : Chest. 152, 6, p. 1097-1099 3 p.

Research output: Contribution to journalEditorial

2 Citations (Scopus)

Bronchiectasis Rheumatoid Overlap Syndrome Is an Independent Risk Factor for Mortality in Patients With Bronchiectasis: A Multicenter Cohort Study

De Soyza, A., McDonnell, M. J., Goeminne, P. C., Aliberti, S., Lonni, S., Davison, J., Dupont, L. J., Fardon, T. C., Rutherford, R. M., Hill, A. T. & Chalmers, J. D., Jun 2017, In : Chest. 151, 6, p. 1247-1254 8 p.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
175 Downloads (Pure)

Community-acquired pneumonia in the United Kingdom: a call to action

Chalmers, J., Campling, J., Ellsbury, G., Hawkey, P. M., Madhava, H. & Slack, M., 5 Oct 2017, In : Pneumonia . 9, 6 p., 15.

Research output: Contribution to journalComment/debate

Open Access
File
171 Downloads (Pure)

Continuous versus intermittent antibiotics for non-cystic fibrosis bronchiectasis

Donovan, T., Felix, L. M., Chalmers, J. D., Milan, S. J., Mathioudakis, A. G. & Spencer, S., 26 Jul 2017, In : Cochrane Database of Systematic Reviews. 2017, 7, p. 1-13 13 p., CD012733.

Research output: Contribution to journalArticle

Open Access
File
98 Downloads (Pure)

Determinants of initial inhaled corticosteroid use in patients with GOLD A/B COPD: a retrospective study of UK general practice

Chalmers, J. D., Tebboth, A., Gayle, A., Ternouth, A. & Ramscar, N., 29 Jun 2017, In : NPJ Primary Care Respiratory Medicine. 27, p. 1-8 8 p., 43.

Research output: Contribution to journalArticle

Open Access
File
26 Citations (Scopus)
167 Downloads (Pure)

European Respiratory Society guidelines for the management of adult bronchiectasis

Polverino, E., Goeminne, P. C., McDonnell, M. J., Aliberti, S., Marshall, S. E., Loebinger, M. R., Murris-Espin, M., Cantón, R., Torres, A., Dimakou, K., De Soyza, A., Hill, A. T., Haworth, C. S., Vendrell, M., Ringshausen, F. C., Subotic, D., Wilson, R., Vilaró, J., Stallberg, B., Welte, T. & 9 others, Rohde, G., Blasi, F., Elborn, J. S., Almagro, M., Timothy, A., Ruddy, T., Tonia, T., Rigau, D. & Chalmers, J. D., Sep 2017, In : European Respiratory Journal. 50, 3, p. 1-23 23 p., 1700629.

Research output: Contribution to journalArticle

Open Access
File
240 Citations (Scopus)
210 Downloads (Pure)

Evaluation of severity score-guided approaches to macrolide use in community-acquired pneumonia

Singanayagam, A., Aliberti, S., Cillóniz, C., Torres, A., Blasi, F. & Chalmers, J. D., Sep 2017, In : European Respiratory Journal. 50, 3, 1602306.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
176 Downloads (Pure)

High endocan levels are associated with the need for mechanical ventilation among patients with severe sepsis

Mangat, M., Amalakuhan, B., Habib, S. A., Reyes, L. F., Hinojosa, C. A., Rodriguez, A. H., Soni, N. J., Anzueto, A., Levine, S. M., Peters, J. I., Aliberti, S., Sibila, O., Rello, J., Witzenrath, M., Waterer, G. W., Martin-Loeches, I., Blanquer, J., Sanz, F., Marcos, P. J., Solé-Violán, J. & 6 others, Chalmers, J. D., Feldman, C., Wunderink, R. G., Cruz, C. S. D., Orihuela, C. J. & Restrepo, M. I., 1 Jul 2017, In : European Respiratory Journal. 50, 1, p. 1-4 4 p., 1700013.

Research output: Contribution to journalLetter

3 Citations (Scopus)

Macrolide resistance in Pseudomonas aeruginosa: implications for practice

Chalmers, J. D., May 2017, In : European Respiratory Journal. 49, 5, p. 1-3 3 p., 1700689.

Research output: Contribution to journalEditorial

3 Citations (Scopus)

Management of chronic airway diseases: What can we learn from real-life data?

Chalmers, J. D., 17 Mar 2017, In : COPD. 14, Suppl. 1, p. S1-S2 2 p.

Research output: Contribution to journalArticle

Open Access
File
192 Downloads (Pure)

Microbial Dysbiosis in Bronchiectasis and Cystic Fibrosis

Dicker, A. J. & Chalmers, J. D., Sep 2017, In : Archivos de Bronconeumologia. 53, 9, p. 471-472 2 p.

Research output: Contribution to journalEditorial

Open Access
File
1 Citation (Scopus)
203 Downloads (Pure)

Neutrophil elastase activity is associated with exacerbations and lung function decline in Bronchiectasis

Chalmers, J. D., Moffitt, K. L., Suarez-Cuartin, G., Sibila, O., Finch, S., Furrie, E., Dicker, A., Wrobel, K., Elborn, J. S., Walker, B., Martin, S. L., Marshall, S. E., Huang, J. T-J. & Fardon, T. C., 15 May 2017, In : American Journal of Respiratory and Critical Care Medicine. 195, 10, p. 1384-1393 10 p.

Research output: Contribution to journalArticle

Open Access
File
81 Citations (Scopus)
143 Downloads (Pure)

New therapies for the prevention and treatment of exacerbations of bronchiectasis

Abo-Leyah, H. & Chalmers, J. D., May 2017, In : Current Opinion in Pulmonary Medicine. 23, 3, p. 218-224 7 p.

Research output: Contribution to journalReview article

Open Access
File
6 Citations (Scopus)
178 Downloads (Pure)

Non-cystic fibrosis bronchiectasis

Finch, S., Dicker, A. & Chalmers, J., 1 Sep 2017, Acute Exacerbations of Pulmonary Diseases. Burgel, P-R., Contoli, M. & López-Campos, J. L. (eds.). European Respiratory Society, p. 38-57 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)