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  • James Chalmers

10 years since TORCH: shining a new light on the risks of inhaled corticosteroids in COPD

Chalmers, J. D. & Keir, H. R., 1 Sep 2017, In : European Respiratory Journal. 50, 3, 5 p., 1701582.

Research output: Contribution to journalEditorial

3 Citations (Scopus)

A 2 × 2 factorial, randomised, open-label trial to determine the clinical and cost-effectiveness of hypertonic saline (HTS 6%) and carbocisteine for airway clearance versus usual care over 52 weeks in adults with bronchiectasis: a protocol for the CLEAR clinical trial

Bradley, J. M., Anand, R., O'Neill, B., Ferguson, K., Clarke, M., Carroll, M., Chalmers, J., De Soyza, A., Duckers, J., Hill, A. T., Loebinger, M. R., Copeland, F., Gardner, E., Campbell, C., Agus, A., McGuire, A., Boyle, R., McKinney, F., Dickson, N., McAuley, D. F. & 1 others, Elborn, S., 19 Dec 2019, In : Trials. 20, 1, p. 1-10 10 p., 747.

Research output: Contribution to journalArticle

Open Access
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28 Downloads (Pure)

A comprehensive approach to lung function in bronchiectasis

Radovanovic, D., Santus, P., Blasi, F., Sotgiu, G., D'Arcangelo, F., Simonetta, E., Contarini, M., Franceschi, E., Goeminne, P. C., Chalmers, J. D. & Aliberti, S., Dec 2018, In : Respiratory Medicine. 145, p. 120-129 10 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
51 Downloads (Pure)

Additional important research priorities for bronchiectasis in China

Aliberti, S., Dhar, R., Aksamit, T. R., Morgan, L. & Chalmers, J. D., 1 Jan 2017, In : European Respiratory Journal. 49, 1, 1602317.

Research output: Contribution to journalLetter

Open Access
File
141 Downloads (Pure)

Advances in bronchiectasis: endotyping, genetics, microbiome, and disease heterogeneity

Flume, P. A., Chalmers, J. D. & Olivier, K. N., 8 Sep 2018, In : The Lancet. 392, 10150, p. 880-890 11 p.

Research output: Contribution to journalReview article

Open Access
File
40 Citations (Scopus)
149 Downloads (Pure)

Airway Bacterial Load and Inhaled Antibiotic Response in Bronchiectasis

Sibila, O., Laserna, E., Shoemark, A., Keir, H. R., Finch, S., Rodrigo-Troyano, A., Perea, L., Lonergan, M., Goeminne, P. C. & Chalmers, J. D., 1 Jul 2019, In : American Journal of Respiratory and Critical Care Medicine. 200, 1, p. 33-41 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Airway Mucin 2 is decreased in patients with severe chronic obstructive pulmonary disease with bacterial colonization

Sibila, O., Garcia-Bellmunt, L., Giner, J., Rodrigo-Troyano, A., Suarez-Cuartin, G., Torrego, A., Castillo, D., Solanes, I., Mateus, E. F., Vidal, S., Sanchez-Reus, F., Sala, E., Cosio, B. G., Restrepo, M. I., Anzueto, A., Chalmers, J. D. & Plaza, V., 1 May 2016, In : Annals of the American Thoracic Society. 13, 5, p. 636-642 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

A new free-cost e-service supporting clinicians to manage their difficult-to-treat tuberculosis cases: The European Respiratory Society-World Health Organization tuberculosis Consilium

D'Ambrosio, L., Tadolini, M., Centis, R., Chalmers, J. D. & Migliori, G. B., 27 Jul 2017, In : Indian Journal of Medical Research. 145, 3, p. 261-263 3 p.

Research output: Contribution to journalEditorial

Open Access
File
19 Downloads (Pure)

Antimicrobial peptides, disease severity and exacerbations in bronchiectasis

Sibila, O., Perea, L., Cantó, E., Shoemark, A., Cassidy, D., Smith, A. H., Suarez-cuartin, G., Rodrigo-troyano, A., Keir, H. R., Oriano, M., Ong, S., Vidal, S., Blasi, F., Aliberti, S. & Chalmers, J. D., Sep 2019, In : Thorax. 74, 9, p. 835-842 8 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
149 Downloads (Pure)

Anti-Pseudomonas aeruginosa IgG antibodies and chronic airway infection in bronchiectasis

Suarez-Cuartin, G., Smith, A., Abo-Leyah, H., Rodrigo-Troyano, A., Perea, L., Vidal, S., Plaza, V., Fardon, T. C., Sibila, O. & Chalmers, J. D., Jul 2017, In : Respiratory Medicine. 128, p. 1-6 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

A point of care neutrophil elastase activity assay identifies bronchiectasis severity, airway infection and risk of exacerbation

Shoemark, A., Cant, E., Carreto, L., Smith, A., Oriano, M., Keir, H. R., Perea, L., Canto, E., Terranova, L., Vidal, S., Moffitt, K., Aliberti, S., Sibila, O. & Chalmers, J. D., 1 Jun 2019, In : European Respiratory Journal. 53, 6, 1900303.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A qualitative synthesis of gastro-oesophageal reflux in bronchiectasis: Current understanding and future risk

McDonnell, M. J., O'Toole, D., Ward, C., Pearson, J. P., Lordan, J. L., De Soyza, A., Loebinger, M., Chalmers, J. D., Laffey, J. G. & Rutherford, R. M., Aug 2018, In : Respiratory Medicine. 141, p. 132-143 12 p.

Research output: Contribution to journalReview article

Open Access
File
5 Citations (Scopus)
106 Downloads (Pure)

A randomised control trial of atorvastatin in bronchiectasis patients infected with Pseudomonas aeruginosa- a proof of concept study

Bedi, P., Chalmers, J. D., Graham, C., Clarke, A., Donaldson, S., Doherty, C. J., Govan, J. R. W., Davidson, D. J., Rossi, A. G. & Hill, A. T., Aug 2017, In : Chest. 152, 2, p. 368-378 11 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
124 Downloads (Pure)
Open Access
File
4 Citations (Scopus)
148 Downloads (Pure)

A systematic review of clinical trial registration in major respiratory journals 2010-2018

Suntila, N. S. M., Smith, A., Al-Dabbagh, Y. & Chalmers, J. D., 6 Dec 2018, In : European Respiratory Journal. 52, 6, 1801491.

Research output: Contribution to journalLetter

Open Access
File
40 Downloads (Pure)

A systematic review of pharmacotherapeutic clinical trial end-points for bronchiectasis in adults

Crichton, M. L., Aliberti, S. & Chalmers, J. D., 31 Mar 2019, In : European Respiratory Review. 28, 151, p. 1-14 14 p., 180108.

Research output: Contribution to journalReview article

Open Access
File
2 Citations (Scopus)
117 Downloads (Pure)

A systematic review of the burden of vaccine preventable pneumococcal disease in UK adults

Chalmers, J. D., Dicker, A., Woodhead, M. & Madhava, H., 11 May 2016, In : BMC Pulmonary Medicine. 16, 1, p. 1-11 11 p., 77.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
181 Downloads (Pure)

British Thoracic Society guideline for bronchiectasis in adults

Hill, A. T., Sullivan, A. L., Chalmers, J. D., De Soyza, A., Elborn, J. S., Floto, R. A., Grillo, L., Gruffydd-Jones, K., Harvey, A., Haworth, C. S., Hiscocks, E., Hurst, J. R., Johnson, C., Kelleher, W. P., Bedi, P., Payne, K., Saleh, H., Screaton, N. J., Smith, M., Tunney, M. & 3 others, Whitters, D., Wilson, R. & Loebinger, M. R., 1 Dec 2018, In : BMJ Open Respiratory Research. 5, 1, 16 p., e000348.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
109 Downloads (Pure)

British Thoracic Society Guideline for bronchiectasis in adults

Hill, A. T., Sullivan, A. L., Chalmers, J. D., De Soyza, A., Elborn, J. S., Floto, R. A., Grillo, L., Gruffydd-Jones, K., Harvey, A., Haworth, C. S., Hiscocks, E., Hurst, J. R., Johnson, C., Kelleher, W. P., Bedi, P., Payne, K., Saleh, H., Screaton, N. J., Smith, M., Tunney, M. & 3 others, Whitters, D., Wilson, R. & Loebinger, M. R., Jan 2019, In : Thorax. 74, Suppl 1, p. 1-69 69 p., 74.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
82 Downloads (Pure)

Bronchiectasis: an emerging global epidemic

Chotirmall, S. H. & Chalmers, J. D., 22 May 2018, In : BMC Pulmonary Medicine. 18, 1, p. 1-3 3 p., 76.

Research output: Contribution to journalEditorial

Open Access
File
5 Citations (Scopus)
106 Downloads (Pure)

Bronchiectasis: new therapies and new perspectives

Chalmers, J. D. & Chotirmall, S. H., Sep 2018, In : The Lancet Respiratory Medicine. 6, 9, p. 715-726 12 p.

Research output: Contribution to journalReview article

Open Access
File
46 Citations (Scopus)
314 Downloads (Pure)

Bronchiectasis

Chalmers, J. D., Chang, A. B., Chotirmall, S. H., Dhar, R. & McShane, P. J., 15 Nov 2018, In : Nature reviews. Disease primers. 4, 1, 1 p., 45.

Research output: Contribution to journalReview article

11 Citations (Scopus)

Bronchiectasis: Phenotyping a Complex Disease

Chalmers, J. D., 17 Mar 2017, In : COPD. 14, Suppl.1, p. S12-S18 7 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
134 Downloads (Pure)

Bronchiectasis: a case-based approach to investigation and management

Contarini, M., Finch, S. & Chalmers, J. D., 30 Sep 2018, In : European Respiratory Review. 27, 149, p. 1-13 13 p., 180016.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
116 Downloads (Pure)

Bronchiectasis and COPD Overlap: A Case of Mistaken Identity?

Chalmers, J. D., Jun 2017, In : Chest. 151, 6, p. 1204-1206 3 p.

Research output: Contribution to journalEditorial

10 Citations (Scopus)

Bronchiectasis Exacerbations Are Heart-Breaking

Chalmers, J. D., 1 Mar 2018, In : Annals of the American Thoracic Society. 15, 3, p. 301-303 3 p.

Research output: Contribution to journalEditorial

Open Access
2 Citations (Scopus)

Bronchiectasis in India: results from the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) and Respiratory Research Network of India Registry

Dhar, R., Singh, S., Talwar, D., Mohan, M., Tripathi, S. K., Swarnakar, R., Trivedi, S., Rajagopala, S., D'Souza, G., Padmanabhan, A., Baburao, A., Mahesh, P. A., Ghewade, B., Nair, G., Jindal, A., Jayadevappa, G. D. H., Sawhney, H., Sarmah, K. R., Saha, K., Anantharaj, S. & 44 others, Khanna, A., Gami, S., Shah, A., Shah, A., Dutt, N., Garg, H., Vyas, S., Venugopal, K., Prasad, R., Aleemuddin, N. M., Karmakar, S., Singh, V., Jindal, S. K., Sharma, S., Prajapat, D., Chandrashekaria, S., McDonnell, M. J., Mishra, A., Rutherford, R., Ramanathan, R. P., Goeminne, P. C., Vasudev, P., Dimakou, K., Crichton, M. L., Jayaraj, B. S., Kungwani, R., Das, A., Sawhney, M., Polverino, E., Torres, A., Gulecha, N. S., Shteinberg, M., De Soyza, A., Mangala, A., Shah, P., Chauhan, N. K., Jajodia, N., Singhal, A., Batra, S., Hasan, A., Limaye, S., Salvi, S., Aliberti, S. & Chalmers, J. D., 1 Sep 2019, In : The Lancet Global Health. 7, 9, p. e1269-e1279 11 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
53 Downloads (Pure)

Bronchiectasis insanity: Doing the same thing over and over again and expecting different results?

Metersky, M. & Chalmers, J., 15 Mar 2019, In : F1000Research. 8, p. 1-7 7 p., 293.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
87 Downloads (Pure)

Bronchiectasis Management: The State of the Union

Chalmers, J. D. & Restrepo, M. I., Dec 2017, In : Chest. 152, 6, p. 1097-1099 3 p.

Research output: Contribution to journalEditorial

2 Citations (Scopus)

Bronchiectasis Rheumatoid Overlap Syndrome Is an Independent Risk Factor for Mortality in Patients With Bronchiectasis: A Multicenter Cohort Study

De Soyza, A., McDonnell, M. J., Goeminne, P. C., Aliberti, S., Lonni, S., Davison, J., Dupont, L. J., Fardon, T. C., Rutherford, R. M., Hill, A. T. & Chalmers, J. D., Jun 2017, In : Chest. 151, 6, p. 1247-1254 8 p.

Research output: Contribution to journalArticle

Open Access
File
27 Citations (Scopus)
155 Downloads (Pure)

Burden and risk factors for Pseudomonas aeruginosa community-acquired pneumonia: a Multinational Point Prevalence Study of Hospitalised Patients

Restrepo, M. I., Babu, B. L., Reyes, L. F., Chalmers, J. D., Soni, N. J., Sibila, O., Faverio, P., Cilloniz, C., Rodriguez-Cintron, W. & Aliberti, S., 9 Aug 2018, In : European Respiratory Journal. 52, 2, 1701190.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
36 Downloads (Pure)

Burden of pneumococcal community-acquired pneumonia in adults across Europe: A literature review

Torres, A., Cillóniz, C., Blasi, F., Chalmers, J. D., Gaillat, J., Dartois, N., Schmitt, H-J. & Welte, T., Apr 2018, In : Respiratory Medicine. 137, p. 6-13 8 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)

Cardiovascular disease as a complication of community-acquired pneumonia

Rae, N., Finch, S. & Chalmers, J. D., May 2016, In : Current Opinion in Pulmonary Medicine. 22, 3, p. 212-218 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Challenges in severe community-acquired pneumonia: a point-of-view review

Torres, A., Chalmers, J. D., Dela Cruz, C. S., Dominedò, C., Kollef, M., Martin-Loeches, I., Niederman, M. & Wunderink, R. G., Feb 2019, In : Intensive Care Medicine. 45, 2, p. 159-171 13 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Characterization of bronchiectasis in the elderly

Bellelli, G., Chalmers, J. D., Sotgiu, G., Dore, S., McDonnell, M. J., Goeminne, P. C., Dimakou, K., Skrbic, D., Lombi, A., Pane, F., Obradovic, D., Fardon, T. C., Rutherford, R. M., Pesci, A. & Aliberti, S., Oct 2016, In : Respiratory Medicine. 119, p. 13-19 7 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
242 Downloads (Pure)

Characterization of the “frequent exacerbator phenotype” in bronchiectasis

Chalmers, J. D., Aliberti, S., Filonenko, A., Shteinberg, M., Goeminne, P. C., Hill, A. T., Fardon, T. C., Obradovic, D., Gerlinger, C., Sotgiu, G., Operschall, E., Rutherford, R. M., Dimakou, K., Polverino, E., De Soyza, A. & McDonnell, M. J., 1 Jun 2018, In : American Journal of Respiratory and Critical Care Medicine. 197, 11, p. 1410-1420 11 p.

Research output: Contribution to journalArticle

Open Access
File
58 Citations (Scopus)
138 Downloads (Pure)

Characterizing non-tuberculous mycobacteria infection in bronchiectasis

Faverio, P., Stainer, A., Bonaiti, G., Zucchetti, S. C., Simonetta, E., Lapadula, G., Marruchella, A., Gori, A., Blasi, F., Codecasa, L., Pesci, A., Chalmers, J. D., Loebinger, M. R. & Aliberti, S., 16 Nov 2016, In : International Journal of Molecular Sciences. 17, 11, 12 p., 1913.

Research output: Contribution to journalArticle

Open Access
File
29 Citations (Scopus)
120 Downloads (Pure)

Circulating desmosine as a biomarker of azithromycin treatment response: a post hoc analysis of the COLUMBUS randomised controlled trial

Chalmers, J. D., Djamin, R. S., Schouten, M., Keir, H. R., Tan, B., Aerts, J. G. J. V., Huang, J. T-J. & van der Eerden, M., Oct 2018, In : ERJ Open Research. 4, 4, p. 1-4 4 p.

Research output: Contribution to journalArticle

Open Access
File
89 Downloads (Pure)

Clinical phenotypes in adult patients with bronchiectasis

Aliberti, S., Lonni, S., Dore, S., McDonnell, M. J., Goeminne, P. C., Dimakou, K., Fardon, T., Rutherford, R., Pesci, A., Restrepo, M. I., Sotgiu, G. & Chalmers, J., 1 Apr 2016, In : European Respiratory Journal. 47, 4, p. 1113-1122 10 p.

Research output: Contribution to journalArticle

Open Access
File
117 Citations (Scopus)
123 Downloads (Pure)

Clinical phenotypes in bronchiectasis: Right on track to develop precision medicine in respiratory diseases

Sotgiu, G., Dore, S., Chalmers, J. D. & Aliberti, S., 1 May 2016, In : International Journal of Tuberculosis and Lung Disease. 20, 5, p. 709 1 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Community-Acquired Pneumonia: A Global Perspective

Feldman, C. & Chalmers, J. D., Dec 2016, In : Seminars in Respiratory and Critical Care Medicine. 37, 6, p. 797-798 2 p.

Research output: Contribution to journalEditorial

Open Access
File
131 Downloads (Pure)

Community-acquired pneumonia in the United Kingdom: a call to action

Chalmers, J., Campling, J., Ellsbury, G., Hawkey, P. M., Madhava, H. & Slack, M., 5 Oct 2017, In : Pneumonia . 9, 6 p., 15.

Research output: Contribution to journalComment/debate

Open Access
File
156 Downloads (Pure)

Community-acquired pneumonia related to intracellular pathogens

Cillóniz, C., Torres, A., Niederman, M., van der Eerden, M., Chalmers, J., Welte, T. & Blasi, F., Sep 2016, In : Intensive Care Medicine. 42, 9, p. 1374-1386 13 p.

Research output: Contribution to journalArticle

Open Access
File
27 Citations (Scopus)
278 Downloads (Pure)

Comorbidities and the risk of mortality in patients with bronchiectasis: an international mulitcentre cohort study

McDonnell, M. J., Aliberti, S., Goeminne, P. C., Restrepo, M. I., Finch, S., Pesci, A., Dupont, L., Fardon, T., Wilson, R., Loebinger, M., Skrbic, D., Obradovic, D., De Soyza, A., Ward, C., Laffey, J. G., Rutherford, R. & Chalmers, J., Dec 2016, In : The Lancet Respiratory Medicine. 4, 12, p. 969-979 11 p.

Research output: Contribution to journalArticle

Open Access
File
75 Citations (Scopus)
138 Downloads (Pure)

Continuous versus intermittent antibiotics for bronchiectasis

Donovan, T., Felix, L. M., Chalmers, J. D., Milan, S. J., Mathioudakis, A. G. & Spencer, S., 3 Jun 2018, In : Cochrane Database of Systematic Reviews. 2018, 6, p. 1-30 30 p., CD012733.

Research output: Contribution to journalReview article

Open Access
File
4 Citations (Scopus)
90 Downloads (Pure)

Continuous versus intermittent antibiotics for non-cystic fibrosis bronchiectasis

Donovan, T., Felix, L. M., Chalmers, J. D., Milan, S. J., Mathioudakis, A. G. & Spencer, S., 26 Jul 2017, In : Cochrane Database of Systematic Reviews. 2017, 7, p. 1-13 13 p., CD012733.

Research output: Contribution to journalArticle

Open Access
File
81 Downloads (Pure)

Control of Confounding and Reporting of Results in Causal Inference Studies: Guidance for Authors from Editors of Respiratory, Sleep, and Critical Care Journals

Lederer, D. J., Bell, S. C., Branson, R. D., Chalmers, J. D., Marshall, R., Maslove, D. M., Ost, D. E., Punjabi, N. M., Schatz, M., Smyth, A. R., Stewart, P. W., Suissa, S., Adjei, A. A., Akdis, C. A., Azoulay, É., Bakker, J., Ballas, Z. K., Bardin, P. G., Barreiro, E., Bellomo, R. & 28 others, Bernstein, J. A., Brusasco, V., Buchman, T. G., Chokroverty, S., Collop, N. A., Crapo, J. D., Fitzgerald, D. A., Hale, L., Hart, N., Herth, F. J., Iwashyna, T. J., Jenkins, G., Kolb, M., Marks, G. B., Mazzone, P., Moorman, J. R., Murphy, T. M., Noah, T. L., Reynolds, P., Riemann, D., Russell, R. E., Sheikh, A., Sotgiu, G., Swenson, E. R., Szczesniak, R., Szymusiak, R., Teboul, J-L. & Vincent, J-L., Jan 2019, In : Annals of the American Thoracic Society. 16, 1, p. 22-28 7 p.

Research output: Contribution to journalArticle

Open Access
File
76 Citations (Scopus)
317 Downloads (Pure)

Corticosteroids for community-acquired pneumonia: a critical view of the evidence

Chalmers, J. D., 1 Oct 2016, In : European Respiratory Journal. 48, 4, p. 984-986 3 p.

Research output: Contribution to journalEditorial

10 Citations (Scopus)

Cross-infection risk in patients with bronchiectasis: a position statement from the European Bronchiectasis Network (EMBARC), EMBARC/ELF patient advisory group and European Reference Network (ERN-Lung) Bronchiectasis Network

Chalmers, J. D., Ringshausen, F. C., Harris, B., Elborn, J. S., Posthumus, A., Haworth, C. S., Pilkington, N., Polverino, E., Ruddy, T., Aliberti, S., Goeminne, P. C., Winstanley, C. & De Soyza, A., 1 Jan 2018, In : European Respiratory Journal. 51, 1, 6 p., 1701937.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
71 Downloads (Pure)

Cystic fibrosis lung disease and bronchiectasis

Chalmers, J. D., Jan 2020, In : The Lancet Respiratory Medicine. 8, 1, p. 12-14 3 p.

Research output: Contribution to journalComment/debate

Open Access
File
4 Downloads (Pure)