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2019
NF-E2 Transcription Factor
NF-E2-Related Factor 2
Air Pollutants
Transcription Factors
Antioxidants
1 Citation (Scopus)
7 Downloads (Pure)

New insights into nuclear factor erythroid 2-related factors in toxicology and pharmacology

Pi, J., Hayes, J. D. & Yamamoto, M., 15 Mar 2019, In : Toxicology and Applied Pharmacology. 367, p. 33-35 3 p.

Research output: Contribution to journalEditorial

Open Access
File
69 Citations (Scopus)
111 Downloads (Pure)

Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases

Cuadrado, A., Rojo, A. I., Wells, G., Hayes, J., Cousin, S. P., Rumsey, W. L., Attucks, O. C., Franklin, S., Levonen, A-L., Kensler, T. W. & Dinkova-Kostova, A., Apr 2019, In : Nature Reviews Drug Discovery. 18, 4, p. 295-317 23 p.

Research output: Contribution to journalReview article

Open Access
File
Chronic Disease
NF-E2-Related Factor 2
Ubiquitin-Protein Ligases
Cytoprotection
Neurodegenerative Diseases
2018
13 Citations (Scopus)
148 Downloads (Pure)

A partnership with the proteasome: the destructive nature of GSK3

Robertson, H., Hayes, J. D. & Sutherland, C., Jan 2018, In : Biochemical Pharmacology. 147, p. 77-92 16 p.

Research output: Contribution to journalArticle

Open Access
File
Glycogen Synthase Kinase 3
Proteasome Endopeptidase Complex
beta-Transducin Repeat-Containing Proteins
Phosphorylation
Proteins
28 Citations (Scopus)
121 Downloads (Pure)
Open Access
File
NF-E2-Related Factor 2
Fructose
Liver Cirrhosis
Fats
Endoplasmic Reticulum Stress
5 Citations (Scopus)
72 Downloads (Pure)
Open Access
File
Cullin Proteins
NF-E2-Related Factor 2
Zinc
Transcription Factors
Switches
2017
8 Citations (Scopus)
106 Downloads (Pure)

Characterization of liver injury, oval cell proliferation and cholangiocarcinogenesis in glutathione S-transferase A3 knockout mice

Crawford, D. R., Ilic, Z., Guest, I., Milne, G. L., Hayes, J. D. & Sell, S., Jul 2017, In : Carcinogenesis. 38, 7, p. 717-727 11 p.

Research output: Contribution to journalArticle

Open Access
File
Aflatoxin B1
Glutathione Transferase
Knockout Mice
Cell Proliferation
Liver
1 Citation (Scopus)

Corrigendum to "Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer"

MacLeod, A. K., Acosta-Jimenez, L., Coates, P. J., McMahon, M., Carey, F. A., Honda, T., Hayes, J. D., Henderson, C. J. & Wolf, C. R., 22 Aug 2017, In : British Journal of Cancer. 117, 1 p., e1.

Research output: Contribution to journalArticle

20 Citations (Scopus)
178 Downloads (Pure)

Crosstalk between NRF2 and HIPK2 shapes cytoprotective responses

Torrente, L., Sanchez, C., Moreno Dorta, R., Chowdhry, S., Cabello, P., Isono, K., Koseki, H., Honda, T., Hayes, J., Dinkova-Kostova, A. & de la Vega, L., 2 Nov 2017, In : Oncogene. 36, 44, p. 6204-6212 9 p.

Research output: Contribution to journalArticle

Open Access
File
Homeodomain Proteins
Protein Kinases
Neoplasms
Phosphotransferases
Oncogenes
3 Citations (Scopus)
208 Downloads (Pure)
Open Access
File
Epigenomics
Antioxidants
Tumor Suppressor Proteins
Acetylation
Oxidation-Reduction
6 Citations (Scopus)
146 Downloads (Pure)
Open Access
File
Oncogenes
Oncogene Proteins
Ligases
Ubiquitin
Genes
2016
13 Citations (Scopus)
111 Downloads (Pure)
Open Access
File
Type 1 Diabetes Mellitus
Hypoglycemia
Rodentia
Oxidative Stress
Inflammation
6 Citations (Scopus)
227 Downloads (Pure)

Regulation of the CNC-bZIP transcription factor Nrf2 by Keap1 and the axis between GSK-3 and β-TrCP

Hayes, J. D., Ebisine, K., Sharma, R. S., Chowdhry, S., Dinkova-Kostova, A. T. & Sutherland, C., Dec 2016, In : Current Opinion in Toxicology. 1, p. 92-103 12 p.

Research output: Contribution to journalReview article

Open Access
File
NF-E2-Related Factor 2
Basic-Leucine Zipper Transcription Factors
Glycogen Synthase Kinase 3
diethyl maleate
Fibroblasts