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2020
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Hepatitis C
Pharmaceutical Preparations
Mortality
Polymerase Chain Reaction
Therapeutics
2019

Adherence to once-daily and twice-daily direct acting antiviral therapy for hepatitis C infection among people with recent injection drug use or current opioid agonist therapy

Cunningham, E. B., Hajarizadeh, B., Amin, J., Litwin, A. H., Gane, E., Cooper, C., Lacombe, K., Hellard, M., Read, P., Powis, J., Dalgard, O., Bruneau, J., Matthews, G. V., Feld, J. J., Dillon, J. F., Shaw, D., Bruggmann, P., Conway, B., Fraser, C., Marks, P. & 2 others, Dore, G. J. & Grebely, J., 2 Nov 2019, In : Clinical Infectious Diseases.

Research output: Contribution to journalArticle

Hepatitis C
Opioid Analgesics
Antiviral Agents
Injections
Infection
27 Downloads (Pure)
Open Access
File
Opiate Substitution Treatment
Hepatitis C
Primary Health Care
Motivation
Patient Acceptance of Health Care
2 Citations (Scopus)
42 Downloads (Pure)
Open Access
File
Hepatitis C
Antiviral Agents
Meta-Analysis
Primary Health Care
Therapeutics
1 Citation (Scopus)
41 Downloads (Pure)

Change in injecting behaviour among people treated for hepatitis C virus: the role of intimate partnerships

Malaguti, A., Sani, F., Stephens, B. P., Ahmad, F., Dugard, P. & Dillon, J., 1 Jan 2019, In : Journal of Viral Hepatitis. 26, 1, p. 65-72 8 p.

Research output: Contribution to journalArticle

Open Access
File
Hepacivirus
Virus Diseases
Therapeutics
Pharmaceutical Preparations
Opiate Alkaloids
8 Citations (Scopus)
25 Downloads (Pure)

Drug-Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles

Nicoletti, P., Aithal, G. P., Chamberlain, T. C., Coulthard, S. A., Alshabeeb, M., Grove, J. I., Andrade, R. J., Bjornsson, E. S., Dillon, J. F., Hallberg, P., Lucena, M. I., Maitland-van der Zee, A. H., Martin, J. H., Molokhia, M., Pirmohamed, M., Wadelius, M., Shen, Y., Nelson, M. R. & Daly, A. K., 1 Jul 2019, In : Clinical Pharmacology & Therapeutics. 106, 1, p. 245-253 9 p.

Research output: Contribution to journalArticle

Open Access
File
Floxacillin
Chemical and Drug Induced Liver Injury
HLA Antigens
Alleles
Penicillins
43 Downloads (Pure)

Evaluating the population impact of hepatitis C direct acting antiviral treatment as prevention for people who inject drugs (EPIToPe): a natural experiment (protocol)

Hickman, M., Dillon, J., Elliott, L., De Angelis, D., Vickerman, P., Foster, G., Donnan, P., Eriksen, A., Flowers, P., Goldberg, D., Hollingworth, W., Ijaz, S., Liddell, D., Mandal, S., Martin, N., Beer, L., Drysdale, K., Fraser, H., Glass, R., Graham, L. & 29 others, Gunson, R. N., Hamilton, E., Harris, H., Harris, M., Harris, R., Heinsbroek, E., Hope, V., Horwood, J., Inglis, S., Innes, H., Lane, A., Meadows, J., McAuley, A., Metcalfe, C., Migchelsen, S., Murray, A., Myring, G., Palmateer, N. E., Presanis, A., Radley, A., Ramsay, M., Samartsidis, P., Simmons, R., Sinka, K., Vojt, G., Ward, Z., Whiteley, D., Yeung, A. & Hutchinson, S. J., 24 Sep 2019, In : BMJ Open. 9, 9, p. 1-12 12 p., e029538.

Research output: Contribution to journalArticle

Open Access
File
Hepatitis C
Hepacivirus
Antiviral Agents
Pharmaceutical Preparations
Population
10 Citations (Scopus)
32 Downloads (Pure)

Hepatitis C elimination among people who inject drugs: Challenges and recommendations for action within a health systems framework

Day, E., Hellard, M., Treloar, C., Bruneau, J., Martin, N. K., Øvrehus, A., Dalgard, O., Lloyd, A., Dillon, J., Hickman, M., Byrne, J., Litwin, A., Maticic, M., Bruggmann, P., Midgard, H., Norton, B., Trooskin, S., Lazarus, J. V. & Grebely, J., 1 Jan 2019, In : Liver International. 39, 1, p. 20-30 11 p.

Research output: Contribution to journalArticle

Open Access
File
Hepatitis C
Health
Pharmaceutical Preparations
Healthcare Financing
Health Information Systems

Hepatitis C reinfection after successful antiviral treatment among people who inject drugs: A meta-analysis

Hajarizadeh, B., Cunningham, E. B., Valerio, H., Martinello, M., Law, M., Janjua, N., Midgard, H., Dalgard, O., Dillon, J., Hickman, M., Bruneau, J., Dore, G. J. & Grebely, J., 27 Nov 2019, In : Journal of Hepatology.

Research output: Contribution to journalArticle

Hepatitis C
Antiviral Agents
Meta-Analysis
Opioid Analgesics
Pharmaceutical Preparations
5 Citations (Scopus)
Hepatitis C
Pharmaceutical Preparations
Therapeutics
Syringes
Equipment and Supplies
2 Citations (Scopus)

Intelligent Liver Function Testing (iLFT): A trial of automated diagnosis and staging of liver disease in Primary Care

Dillon, J. F., Miller, M. H., Robinson, E. M., Hapca, A., Rezaeihemami, M., Weatherburn, C., McIntyre, P. G., Bartlett, B., Donnan, P. T., Boyd, K. A. & Dow, E., Oct 2019, In : Journal of Hepatology. 71, 4, p. 699-706 8 p.

Research output: Contribution to journalArticle

Liver Function Tests
Liver Diseases
Primary Health Care
Liver
Costs and Cost Analysis
2 Citations (Scopus)
42 Downloads (Pure)

Interferon lambda 4 impacts the genetic diversity of hepatitis C virus

Ansari, M. A., Aranday-Cortes, E., Ip, C. L. C., da Silva Filipe, A., Lau, S. H., Bamford, C., Bonsall, D., Trebes, A., Piazza, P., Sreenu, V., Cowton, V. M., STOP-HCV Consortium, Hudson, E., Bowden, R., Patel, A. H., Foster, G. R., Irving, W. L., Agarwal, K., Thomson, E. C., Simmonds, P. & 6 others, Klenerman, P., Holmes, C., Barnes, E., Spencer, C. C. A., McLauchlan, J. & Pedergnana, V., 3 Sep 2019, In : eLife. 8, p. 1-23 23 p., e42463.

Research output: Contribution to journalArticle

Open Access
File
Viruses
Hepacivirus
Interferons
Viral Genome
Genes
24 Downloads (Pure)

New Horizons in Hepatitis B and C in the Older Adult

Kemp, L., Clare, K. E., Brennan, P. N. & Dillon, J. F., 1 Jan 2019, In : Age and Ageing. 48, 1, p. 32-37 6 p., afy170.

Research output: Contribution to journalArticle

Open Access
File
Hepatitis C
Hepatitis B
Sexual Partners
Infection
Viruses
53 Downloads (Pure)
Open Access
File
Hepatitis C
Scotland
Randomized Controlled Trials
Equipment and Supplies
Pharmaceutical Preparations

Real-world impact following initiation of interferon-free hepatitis C regimens on liver-related outcomes and all-cause mortality among patients with compensated cirrhosis

McDonald, S. A., Pollock, K. G., Barclay, S. T., Goldberg, D. J., Bathgate, A., Bramley, P., Dillon, J. F., Fraser, A., Innes, H. A., Kennedy, N., Morris, J., Went, A., Hayes, P. C. & Hutchinson, S. J., 26 Nov 2019, In : Journal of Viral Hepatitis. 11 p.

Research output: Contribution to journalArticle

Hepatitis C
Interferons
Fibrosis
Mortality
Liver
1 Citation (Scopus)
92 Downloads (Pure)

Safety and efficacy of glecaprevir/pibrentasvir in patients with chronic hepatitis C genotypes 1-6 receiving opioid substitution therapy

Grebely, J., Dore, G. J., Alami, N. N., Conway, B., Dillon, J. F., Gschwantler, M., Felizarta, F., Hézode, C., Tomasiewicz, K., Fredrick, L. M., Dumas, E. O. & Mensa, F. J., Apr 2019, In : International Journal of Drug Policy. 66, p. 73-79 7 p.

Research output: Contribution to journalArticle

Open Access
File
Opiate Substitution Treatment
Chronic Hepatitis C
Genotype
Safety
Hepacivirus

The Consensus Hepatitis C Cascade of Care: standardized reporting to monitor progress toward elimination

Safreed-Harmon, K., Blach, S., Aleman, S., Boe Kielland, K., Bollerup, S., Cooke, G., Dalgard, O., Dillon, J. F., Dore, G. J., Duberg, A-S., Grebely, J., Midgard, H., Porter, K., Razavi, H., Tyndall, M., Weis, N. & Lazarus, J. V., 28 Jul 2019, In : Clinical Infectious Diseases. 69, 12, p. 2218-2227 10 p., ciz714.

Research output: Contribution to journalArticle

Hepatitis C
Hepacivirus
Consensus
Federal Government
Denmark
2 Citations (Scopus)

Too many people with viral hepatitis are diagnosed late - with dire consequences

Lazarus, J. V., Picchio, C., Dillon, J. F., Rockstroh, J. K., Weis, N. & Buti, M., 19 Aug 2019, In : Nature Reviews Gastroenterology & Hepatology. 16, 8, p. 451-452 2 p.

Research output: Contribution to journalComment/debate

Hepatitis
Hepatitis B virus
Hepacivirus
Liver Diseases
Public Health
6 Citations (Scopus)
78 Downloads (Pure)

Top research priorities in liver and gallbladder disorders in the UK

Gurusamy, K. S., Walmsley, M., Davidson, B. R., Frier, C., Fuller, B., Madden, A., Masson, S., Morley, R., Safarik, I., Tsochatzis, E. A., Ahmed, I., Cowlin, M., Dillon, J. F., Ellicott, G., Elsharkawy, A. M., Farrington, L., Glachan, A., Kumar, N., Milne, E. J., Rushbrook, S. M. & 3 others, Smith, A., Stafford, L. & Yeoman, A., 7 Mar 2019, In : BMJ Open. 9, 3, 1 p., e025045.

Research output: Contribution to journalArticle

Open Access
File
Gallbladder
Liver
Research
Caregivers
Consensus Development Conferences
2 Citations (Scopus)

Uptake of endoscopic screening for gastroesophageal varices and factors associated with variceal bleeding in patients with chronic hepatitis C infection and compensated cirrhosis, 2005-2016: a national database linkage study

McDonald, S. A., Barclay, S. T., Hutchinson, S. J., Stanley, A. J., Fraser, A., Dillon, J. F., Innes, H. A., Peters, E., Kennedy, N., Bathgate, A., Bramley, P., Morris, J., Goldberg, D. J. & Hayes, P. C., Aug 2019, In : Alimentary Pharmacology & Therapeutics. 50, 4, p. 425-434 10 p.

Research output: Contribution to journalArticle

Varicose Veins
Chronic Hepatitis C
Fibrosis
Databases
Hemorrhage
1 Citation (Scopus)

We know DAAs work, so now what? Simplifying models of care to enhance the hepatitis C cascade

Lazarus, J. V., Pericàs, J. M., Picchio, C., Cernosa, J., Hoekstra, M., Luhmann, N., Maticic, M., Read, P., Robinson, E. M. & Dillon, J. F., Nov 2019, In : Journal of Internal Medicine. 286, 5, p. 503-525 23 p.

Research output: Contribution to journalReview article

Hepatitis C
Hepacivirus
Interferons
Therapeutics
Standard of Care
2018
7 Citations (Scopus)
32 Downloads (Pure)

Adherence to sofosbuvir and velpatasvir among people with chronic HCV infection and recent injection drug use: The SIMPLIFY study

Cunningham, E. B., Amin, J., Feld, J. J., Bruneau, J., Dalgard, O., Powis, J., Hellard, M., Cooper, C., Read, P., Conway, B., Dunlop, A. J., Norton, B., Litwin, A. H., Hajarizadeh, B., Thurnheer, M. C., Dillon, J. F., Weltman, M., Shaw, D., Bruggmann, P., Gane, E. & 8 others, Fraser, C., Marks, P., Applegate, T. L., Quiene, S., Siriragavan, S., Matthews, G. V., Dore, G. J. & Grebely, J., Dec 2018, In : International Journal of Drug Policy. 62, p. 14-23 10 p.

Research output: Contribution to journalArticle

Open Access
File
Injections
Infection
Pharmaceutical Preparations
Therapeutics
Blister
4 Citations (Scopus)
92 Downloads (Pure)
Open Access
File
Opiate Substitution Treatment
Hepatitis C
Pharmacists
Hepacivirus
Antiviral Agents
78 Downloads (Pure)

Correction to: Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease

Spanos, C., Maldonado, E. M., Fisher, C. P., Leenutaphong, P., Oviedo-Orta, E., Windridge, D., Salguero, F. J., Bermúdez-Fajardo, A., Weeks, M. E., Evans, C., Corfe, B. M., Rabbani, N., Thornalley, P. J., Miller, M. H., Wang, H., Dillon, J. F., Quaglia, A., Dhawan, A., Fitzpatrick, E. & Moore, J. B., 25 Jun 2018, In : Proteome Science. 16, 13, p. 13 1 p., 13.

Research output: Contribution to journalComment/debate

Open Access
File
Liver
Proteomics
Non-alcoholic Fatty Liver Disease
2 Citations (Scopus)
184 Downloads (Pure)

Development and validation of diagnostic triage criteria for liver disease from a minimum data set enabling the 'intelligent LFT' pathway for the automated assessment of deranged liver enzymes

Miller, M. H., Fraser, A., Leggett, G., MacGilchrist, A., Gibson, G., Orr, J., Forrest, E. H., Dow, E., Bartlett, W., Weatherburn, C., Laurell, A., Grant, K., Scott, K., Neville, R. & Dillon, J. F., Jul 2018, In : Frontline Gastroenterology. 9, 3, p. 175-182 8 p.

Research output: Contribution to journalArticle

Open Access
File
Triage
Liver Function Tests
Liver Diseases
Primary Health Care
Liver
39 Citations (Scopus)
279 Downloads (Pure)

Disease burden and costs from excess alcohol consumption, obesity, and viral hepatitis: fourth report of the Lancet Standing Commission on Liver Disease in the UK

Williams, R., Alexander, G., Armstrong, I., Baker, A., Bhala, N., Camps-Walsh, G., Cramp, M. E., de Lusignan, S., Day, N., Dhawan, A., Dillon, J., Drummond, C., Dyson, J., Foster, G., Gilmore, I., Hudson, M., Kelly, D., Langford, A., McDougall, N., Meier, P. & 14 others, Moriarty, K., Newsome, P., O'Grady, J., Pryke, R., Rolfe, L., Rice, P., Rutter, H., Sheron, N., Taylor, A., Thompson, J., Thorburn, D., Verne, J., Wass, J. & Yeoman, A., 17 Mar 2018, In : Lancet. 391, 10125, p. 1097-1107 11 p.

Research output: Contribution to journalReview article

Open Access
File
Cost of Illness
Alcohol Drinking
Hepatitis
Liver Diseases
Obesity

Editorial: there is trouble ahead, but just how much? The troubling reality of America's excesses and NAFLD

Brennan, P. N. & Dillon, J. F., Jan 2018, In : Alimentary Pharmacology & Therapeutics. 47, 2, p. 299-300 2 p.

Research output: Contribution to journalEditorial

Open Access
29 Citations (Scopus)
122 Downloads (Pure)
Open Access
File
NF-E2-Related Factor 2
Fructose
Liver Cirrhosis
Fats
Endoplasmic Reticulum Stress
18 Citations (Scopus)
248 Downloads (Pure)

Gathering momentum for the way ahead: fifth report of the Lancet Standing Commission on Liver Disease in the UK

Williams, R., Alexander, G., Aspinall, R., Batterham, R., Bhala, N., Bosanquet, N., Severi, K., Burton, A., Burton, R., Cramp, M. E., Day, N., Dhawan, A., Dillon, J., Drummond, C., Dyson, J., Foster, G. R., Gilmore, I., Greenberg, J., Henn, C., Hudson, M. & 18 others, Jarvis, H., Kelly, D., Mann, J., McDougall, N., McKee, M., Moriarty, K., Morling, J., Newsome, P., O'Grady, J., Rolfe, L., Rice, P., Rutter, H., Sheron, N., Thorburn, D., Verne, J., Vohra, J., Wass, J. & Yeoman, A., 1 Dec 2018, In : Lancet. 392, 10162, p. 2398-2412 15 p.

Research output: Contribution to journalArticle

Open Access
File
Liver Diseases
Obesity
Alcohols
National Health Programs
Costs and Cost Analysis
44 Citations (Scopus)
145 Downloads (Pure)

Guidelines on the management of abnormal liver blood tests

Newsome, P. N. G., Cramb, R., Davison, S. M., Dillon, J. F., Foulerton, M., Godfrey, E. M., Hall, R., Harrower, U., Hudson, M., Langford, A., Mackie, A., Mitchell-Thain, R., Sennett, K., Sheron, N. C., Verne, J., Walmsley, M. & Yeoman, A., Jan 2018, In : Gut. 67, 1, p. 6-19 14 p.

Research output: Contribution to journalArticle

Open Access
File
Hematologic Tests
Guidelines
Liver
Gastroenterology
Patient Advocacy
11 Citations (Scopus)
116 Downloads (Pure)

High response and re-infection rates among people who inject drugs treated for hepatitis C in a community needle and syringe programme

Schulkind, J., Stephens, B., Ahmad, F., Johnston, L., Hutchinson, S., Thain, D., Ward, Z., Vickerman, P., Hickman, M. & Dillon, J. F., 13 Nov 2018, In : Journal of Viral Hepatitis. 10 p.

Research output: Contribution to journalArticle

Open Access
File
Syringes
Hepatitis C
Hepacivirus
Needles
Genotype
8 Citations (Scopus)
89 Downloads (Pure)

Impact of current and scaled-up levels of hepatitis C prevention and treatment interventions for people who inject drugs in three UK settings: what is required to achieve the WHO's HCV elimination targets?

Ward, Z., Platt, L., Sweeney, S., Hope, V. D., Maher, L., Hutchinson, S., Palmateer, N., Smith, J., Craine, N., Taylor, A., Martin, N., Ayres, R., Dillon, J., Hickman, M. & Vickerman, P., Sep 2018, In : Addiction. 113, 9, p. 1727-1738 12 p.

Research output: Contribution to journalArticle

Open Access
File
Opiate Substitution Treatment
Hepatitis C
Hepacivirus
Pharmaceutical Preparations
Syringes
4 Citations (Scopus)
92 Downloads (Pure)

Impact of previous hepatitis B infection on the clinical outcomes from chronic hepatitis C? A population-level analysis

Wang, H., Swann, R., Thomas, E., Innes, H. A., Valerio, H., Hayes, P. C., Allen, S., Barclay, S. T., Wilks, D., Fox, R., Bhattacharyya, D., Kennedy, N., Morris, J., Fraser, A., Stanley, A. J., Gunson, R., Mclntyre, P. G., Hunt, A., Hutchinson, S. J., Mills, P. R. & 1 others, Dillon, J. F., 1 Aug 2018, In : Journal of Viral Hepatitis. 25, 8, p. 930-938 9 p.

Research output: Contribution to journalArticle

Open Access
File
Chronic Hepatitis C
Hepatitis B
Hepatitis B virus
Virus Diseases
Hepacivirus
38 Citations (Scopus)
96 Downloads (Pure)

Model projections on the impact of HCV treatment in the prevention of HCV transmission among people who inject drugs in Europe"

Fraser, H., Martin, N. K., Brummer-Korvenkontio, H., Carrieri, P., Dalgard, O., Dillon, J., Goldberg, D., Hutchinson, S., Jauffret-Roustide, M., Kåberg, M., Matser, A. A., Matičič, M., Midgard, H., Mravcik, V., Øvrehus, A., Prins, M., Reimer, J., Robaeys, G., Schulte, B., van Santen, D. K. & 3 others, Zimmermann, R., Vickerman, P. & Hickman, M., 1 Mar 2018, In : Journal of Hepatology. 68, 3, p. 402-411 10 p.

Research output: Contribution to journalArticle

Open Access
File
Hepacivirus
Opiate Substitution Treatment
Pharmaceutical Preparations
Syringes
Slovenia
6 Citations (Scopus)
126 Downloads (Pure)

Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease

Spanos, C., Maldonado, E. M., Fisher, C. P., Leenutaphong, P., Oviedo-Orta, E., Windridge, D., Salguero, F. J., Bermúdez-Fajardo, A., Weeks, M. E., Evans, C., Corfe, B. M., Rabbani, N., Thornalley, P. J., Miller, M. H., Wang, H., Dillon, J. F., Quaglia, A., Dhawan, A., Fitzpatrick, E. & Bernadette Moore, J., 14 Feb 2018, In : Proteome Science. 16, p. 1-16 16 p., 4.

Research output: Contribution to journalArticle

Open Access
File
Liver
Proteomics
Pyruvaldehyde
Biopsy
Biomarkers
61 Citations (Scopus)
242 Downloads (Pure)

Sofosbuvir and velpatasvir for hepatitis C virus infection in people with recent injection drug use (SIMPLIFY): an open-label, single-arm, phase 4, multicentre trial

Grebely, J., Dalgard, O., Conway, B., Cunningham, E. B., Bruggmann, P., Hajarizadeh, B., Amin, J., Bruneau, J., Hellard, M., Litwin, A. H., Marks, P., Quiene, S., Siriragavan, S., Applegate, T. L., Swan, T., Byrne, J., Lacalamita, M., Dunlop, A., Matthews, G. V., Powis, J. & 12 others, Shaw, D., Thurnheer, M. C., Weltman, M., Kronborg, I., Cooper, C., Feld, J. J., Fraser, C., Dillon, J. F., Read, P., Gane, E., Dore, G. J. & on behalf of the SIMPLIFY Study Group, Mar 2018, In : Lancet Gastroenterology and Hepatology. 3, 3, p. 153-161 9 p.

Research output: Contribution to journalArticle

Open Access
File
Virus Diseases
Hepacivirus
Multicenter Studies
Injections
Pharmaceutical Preparations
21 Citations (Scopus)
60 Downloads (Pure)

The Micro-Elimination Approach to Eliminating Hepatitis C: Strategic and Operational Considerations

Lazarus, J. V., Safreed-Harmon, K., Thursz, M. R., Dillon, J. F., El-Sayed, M. H., Elsharkawy, A. M., Hatzakis, A., Jadoul, M., Prestileo, T., Razavi, H., Rockstroh, J. K., Wiktor, S. Z. & Colombo, M., 1 Aug 2018, In : Seminars in Liver Disease. 38, 3, p. 181-192 12 p.

Research output: Contribution to journalArticle

Open Access
File
Hepatitis C
Hepacivirus
Population
Prisoners
Health Services Needs and Demand
18 Citations (Scopus)
123 Downloads (Pure)

The risk of hepatocellular carcinoma in cirrhotic patients with hepatitis C and sustained viral response: role of the treatment regimen

Innes, H. A., Barclay, S. T., Hayes, P. C., Fraser, A., Dillon, J. F., Stanley, A. J., Bathgate, A., McDonald, S. A., Goldberg, D., Valerio, H., Fox, R., Kennedy, N., Bramley, P. & Hutchinson, S. J., Apr 2018, In : Journal of Hepatology. 68, 4, p. 646-654 10 p.

Research output: Contribution to journalArticle

Open Access
File
Hepatitis C
Hepatocellular Carcinoma
Interferons
Therapeutics
Liver Neoplasms
2017
13 Citations (Scopus)
151 Downloads (Pure)

A quasi-experimental evaluation of dried blood spot testing through community pharmacies in the Tayside region of Scotland

Radley, A., Melville, K., Tait, J., Stephens, B., Evans, J. M. M. & Dillon, J. F., 1 Jul 2017, In : Frontline Gastroenterology. 8, 3, p. 221-228 8 p.

Research output: Contribution to journalArticle

Open Access
File
Dried Blood Spot Testing
Pharmacies
Scotland
Community Pharmacy Services
Opiate Substitution Treatment
73 Citations (Scopus)
169 Downloads (Pure)

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-wide Association Study

Nicoletti, P., Aithal, G. P., Bjornsson, E. S., Andrade, R. J., Sawle, A., Arrese, M., Barnhart, H. X., Bondon-Guitton, E., Hayashi, P. H., Bessone, F., Carvajal, A., Cascorbi, I., Cirulli, E. T., Chalasani, N., Conforti, A., Coulthard, S. A., Daly, M. J., Day, C. P., Dillon, J. F., Fontana, R. J. & 27 others, Grove, J. I., Hallberg, P., Hernández, N., Ibáñez, L., Kullak-Ublick, G. A., Laitinen, T., Larrey, D., Lucena, M. I., Maitland-van der Zee, A. H., Martin, J. H., Molokhia, M., Pirmohamed, M., Powell, E. E., Qin, S., Serrano, J., Stephens, C., Stolz, A., Wadelius, M., Watkins, P. B., Floratos, A., Shen, Y., Nelson, M. R., Urban, T. J., Daly, A. K., International DILI consortium (iDILIC), Drug-induced liver injury network (DILIN) investigators & International Serious Adverse Events Consortium (iSAEC), Apr 2017, In : Gastroenterology. 152, 5, p. 1078-1089 12 p.

Research output: Contribution to journalArticle

Open Access
File
Chemical and Drug Induced Liver Injury
Genome-Wide Association Study
HLA Antigens
Liver
Wounds and Injuries
7 Citations (Scopus)
88 Downloads (Pure)

Cohort Profile: The Hepatitis C Virus (HCV) Research UK Clinical Database and Biobank

McLauchlan, J., Innes, H., Dillon, J. F., Foster, G., Holtham, E., McDonald, S., Wilkes, B., Hutchinson, S. J., Irving, W. L. & on behalf of the HCV Research UK Steering Committee, Oct 2017, In : International Journal of Epidemiology. 46, 5, p. 1391-1391h 9 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
113 Downloads (Pure)
Open Access
File
Pharmacies
Opioid Analgesics
Pharmacists
Dried Blood Spot Testing
Population
1 Citation (Scopus)

Editorial: sorafenib toxicity, a biomarker of effect?

Clare, K. E., Miller, M. H. & Dillon, J. F., Jun 2017, In : Alimentary Pharmacology & Therapeutics. 45, 11, p. 1469-1470 2 p.

Research output: Contribution to journalEditorial

124 Downloads (Pure)

Genetic factors influencing drug induced liver injury: do they have a role in prevention and diagnosis?

Clare, K. E., Miller, M. H. & Dillon, J. F., Sep 2017, In : Current Hepatology Reports. 16, 3, p. 258-264 7 p.

Research output: Contribution to journalReview article

Open Access
File
Chemical and Drug Induced Liver Injury
Alleles
Floxacillin
Clavulanic Acid
Precision Medicine
40 Citations (Scopus)

Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus

Ansari, M. A., Pedergnana, V., Ip, C. L. C., Magri, A., Von Delft, A., Bonsall, D., Chaturvedi, N., Bartha, I., Smith, D., Nicholson, G., McVean, G., Trebes, A., Piazza, P., Fellay, J., Cooke, G., Foster, G. R., Hudson, E., McLauchlan, J., Simmonds, P., Bowden, R. & 29 others, Klenerman, P., Barnes, E., Spencer, C. C. A., Ball, J., Brainard, D. M., Burgess, G., Dillon, J., Gore, C., Guha, N., Halford, R., Herath, C., Holmes, C., Howe, A., Irving, W., Khakoo, S., Koletzki, D., Martin, N. K., Massetto, B., Mbisa, T., McHutchison, J. G., McKeating, J., Miners, A., Murray, A., Shaw, P. J., Targett-Adams, P., Thomson, E., Vickerman, P., Zitzmann, N. & STOP-HCV Consortium, 10 Apr 2017, In : Nature Genetics. 49, 5, p. 666-673 8 p.

Research output: Contribution to journalArticle

Hepacivirus
Immune System
Genome
Genotype
Gene Components
2 Citations (Scopus)
125 Downloads (Pure)

Limited Impact of Awareness-Raising Campaigns on Hepatitis C Testing Practices among General Practitioners

McLeod, A., Cullen, B. L., Hutchinson, S. J., Roy, K. M., Dillon, J. F., Stewart, E. A. & Goldberg, D. J., 12 Oct 2017, In : Journal of Viral Hepatitis. 24, 1, p. 944-954 11 p.

Research output: Contribution to journalArticle

Open Access
File
Hepatitis C
General Practitioners
Tooth
Scotland
Hepatitis
41 Citations (Scopus)
171 Downloads (Pure)

Minocycline hepatotoxicity: Clinical characterization and identification of HLA-B*35:02 as a risk factor

Urban, T. J., Nicoletti, P., Chalasani, N. P., Serrano, J., Stolz, A., Daly, A. K., Aithal, G. P., Dillon, J., Navarro, V., Odin, J., Barnhart, H. X., Ostrov, D., Long, N., Cirulli, E. T., Watkins, P. B. & Fontana, R. J., Jul 2017, In : Journal of Hepatology. 67, 1, p. 137-144 8 p.

Research output: Contribution to journalArticle

Open Access
File
Minocycline
HLA Antigens
Population Control
Alleles
Liver
21 Citations (Scopus)
143 Downloads (Pure)

Mortality in hepatitis C patients who achieve a sustained viral response compared to the general population

Innes, H., McDonald, S., Hayes, P., Dillon, J. F., Allen, S., Goldberg, D., Mills, P. R., Barclay, S. T., Wilks, D., Valerio, H., Fox, R., Bhattacharyya, D., Kennedy, N., Morris, J., Fraser, A., Stanley, A., Bramley, P. & Hutchinson, S. J., Jan 2017, In : Journal of Hepatology. 66, 1, p. 19-27 9 p.

Research output: Contribution to journalArticle

Open Access
File
Hepatitis C
Mortality
Population
Liver Neoplasms
Pharmaceutical Preparations
8 Citations (Scopus)
120 Downloads (Pure)

Multidisciplinary managed care networks-Life-saving interventions for hepatitis C patients

Tait, J. M., Wang, H., Stephens, B. P., Miller, M., McIntyre, P. G., Cleary, S. & Dillon, J. F., Mar 2017, In : Journal of Viral Hepatitis. 24, 3, p. 207-215 9 p.

Research output: Contribution to journalArticle

Open Access
File
Managed Care Programs
Hepatitis C
Hepacivirus
Hepatitis C Antibodies
Mortality
16 Citations (Scopus)
279 Downloads (Pure)

New metrics for the Lancet Standing Commission on Liver Disease in the UK

Williams, R., Alexander, G., Aspinall, R., Bosanquet, J., Camps-Walsh, G., Cramp, M., Day, N., Dhawan, A., Dillon, J., Dyson, J., Ferguson, J., Foster, G., Gardner, R., Gilmore, S. I., Hardman, L., Hudson, M., Kelly, D., Langford, A., Liversedge, S., Moriarty, K. & 12 others, Newsome, P., O'Grady, J., Pryke, R., Rolfe, L., Rutter, H., Ryder, S., Samyn, M., Sheron, N., Taylor, A., Thompson, J., Verne, J. & Yeoman, A., 20 May 2017, In : Lancet. 389, 10083, p. 2053-2080 29 p.

Research output: Contribution to journalArticle

Open Access
File