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2020
30 Downloads (Pure)

A Mendelian randomization study provides evidence that adiposity and dyslipidemia lead to lower urinary albumin creatinine ratio, a marker of microvascular function

Casanova, F., Wood, A. R., Yaghootkar, H., Beaumont, R. N., Jones, S. E., Gooding, K. M., Aizawa, K., Strain, W. D., Hattersley, A. T., Khan, F., Shore, A. C., Frayling, T. M. & Tyrrell, J., 8 Jan 2020, In : Diabetes.

Research output: Contribution to journalArticle

Open Access
File
Adiposity
Dyslipidemias
Random Allocation
Albumins
Creatinine
2019
11 Citations (Scopus)
59 Downloads (Pure)

A Randomized Controlled Trial of Metformin on Left Ventricular Hypertrophy in Patients with Coronary Artery Disease without Diabetes: The MET-REMODEL Trial

Mohan, M., Al-Talabany, S., McKinnie, A., Mordi, I., Singh, J., Gandy, S., Baig, F., Hussain, M. S. ., Bhalraam, U., Khan, F., Choy, A., Matthew, S., Houston, G., Struthers, A., George, J. & Lang, C. C., 1 Nov 2019, In : European Heart Journal. 40, 41, p. 3409-3417 9 p.

Research output: Contribution to journalArticle

Open Access
File
Metformin
Left Ventricular Hypertrophy
Coronary Artery Disease
Randomized Controlled Trials
Insulin Resistance
4 Citations (Scopus)
30 Downloads (Pure)

Cardiovascular Effects of Switching from Tobacco Cigarettes to Electronic Cigarettes

George, J., Hussain, M., Vadiveloo, T., Ireland, S., Hopkinson, P., Struthers, A. D., Donnan, P. T., Khan, F. & Lang, C. C., 15 Nov 2019, In : Journal of the American College of Cardiology. 9 p.

Research output: Contribution to journalArticle

Open Access
File
Tobacco Products
Tobacco
Blood Vessels
Nicotine
Dilatation

CD44 contributes to hyaluronan-mediated insulin resistance in skeletal muscle of high fat-fed C57BL/6 mice

Hasib, A., Hennayake, C., Bracy, D. P., Bugler-Lamb, A-R., Lantier, L., Khan, F., Ashford, M., McCrimmon, R., Wasserman, D. H. & Kang, L., 1 Dec 2019, In : American Journal of Physiology, Endocrinology and Metabolism. 317, 6, p. E973-E983 11 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Inbred C57BL Mouse
Insulin Resistance
Skeletal Muscle
Fats
64 Downloads (Pure)

Inhibition of NFAT Signaling Restores Microvascular Endothelial Function in Diabetic Mice

Garcia-Vaz, E., McNeilly, A. D., Berglund, L. M., Ahmad, A., Gallagher, J. R., Dutius Andersson, A-M., McCrimmon, R. J., Zetterqvist, A. V., Gomez, M. F. & Khan, F., Dec 2019, In : Diabetes. 68, 12, p. 1-50 50 p., 180870.

Research output: Contribution to journalArticle

Open Access
File
A 285222
Iontophoresis
Microvessels
Skin
Osteopontin
1 Citation (Scopus)
92 Downloads (Pure)
Open Access
File
Oxidative Stress
Skin
Wavelet Analysis
Fluorescence Spectrometry
Arterioles
6 Citations (Scopus)
81 Downloads (Pure)

Metformin is the key factor for elevated plasma GDF-15 levels in type 2 diabetes: a nested, case-control study

SUMMIT Consortium, Natali, A., Nesti, L., Venturi, E., Shore, A. C., Khan, F., Gooding, K., Gates, P. E., Looker, H. C., Dove, F., Goncalves, I., Persson, M. & Nilsson, J., 10 Jan 2019, In : Diabetes, Obesity & Metabolism. 21, 2, p. 412-416 5 p.

Research output: Contribution to journalArticle

Open Access
File
Growth Differentiation Factor 15
Metformin
Type 2 Diabetes Mellitus
Case-Control Studies
Diuretics
71 Downloads (Pure)

Peripheral Vascular Responses to Acetylcholine as a Predictive Tool for Response to Cholinesterase Inhibitors in Alzheimer's Disease

Connelly, P., Adams, F., Tayar, Z. I. & Khan, F., 3 May 2019, In : BMC Neurology. 19, 1, p. 1-7 7 p., 88.

Research output: Contribution to journalArticle

Open Access
File
Cholinesterase Inhibitors
Acetylcholine
Blood Vessels
Alzheimer Disease
Iontophoresis
41 Downloads (Pure)

Potential mechanisms for the effects of far-infrared on the cardiovascular system: a review

Shemilt, R., Bagabir, H., Lang, C. & Khan, F., Jul 2019, In : VASA. 48, 4, p. 303-312 10 p.

Research output: Contribution to journalArticle

Open Access
File
Cardiovascular System
Protein Precursors
Nitric Oxide Synthase Type III
Arteriovenous Fistula
Therapeutic Uses
2018
1 Citation (Scopus)
198 Downloads (Pure)

Application of cmOCT and continuous wavelet transform analysis to the assessment of skin microcirculation dynamics

Smirni, S., MacDonald, M., Robertson, C., McNamara, P. M., O'Gorman, S., Leahy, M. J. & Khan, F., 10 Jul 2018, In : Journal of Biomedical Optics. 23, 7, p. 1-13 13 p., 076006.

Research output: Contribution to journalArticle

Open Access
File
Microcirculation
Optical tomography
wavelet analysis
Wavelet transforms
Skin
7 Citations (Scopus)
81 Downloads (Pure)

Development and Validation of a Path Length Calculation for Carotid-Femoral Pulse Wave Velocity Measurement: A TASCFORCE, SUMMIT, and Caerphilly Collaborative Venture

Weir-McCall, J., Brown, L. K., Summersgill, J., Talarczyk, P., Bonnici-Mallia, M., Chin, S. C., Khan, F., Struthers, A., Sullivan, F., Colhoun, H. M., Shore, A. C., Aizawa, K., Groop, L. C., Nilsson, J., Cockcroft, J. R., McEniery, C. M., Wilkinson, I. B., Ben-Shlomo, Y. & Houston, J. G., May 2018, In : Hypertension. 71, 5, p. 937-945 9 p.

Research output: Contribution to journalArticle

Open Access
File
Pulse Wave Analysis
Thigh
Angiography
Magnetic Resonance Spectroscopy
Confidence Intervals
20 Citations (Scopus)
99 Downloads (Pure)

Effect of vitamin D supplementation on markers of vascular function: a systematic review and individual participant meta-analysis

Beveridge, L., Khan, F., Struthers, A., Armitage, J., Barchetta, I., Cavallo, M. G., Clarke, R., Dalan, R., Dreyer, G., Gepner, A. D., Forouhi, N. G., Harris, R. A. ., Hitman, G. A., Larsen, T., Khadgawat, R., Marckmann, P., Mose, F. H. ., Pilz, S., Scholze, A., Shargorodsky, M. & 4 others, Sokol, S. I., Stricker, H., Zoccali, C. & Witham, M., 30 May 2018, In : Journal of the American Heart Association. 7, 11, p. 1-21 21 p., e008273.

Research output: Contribution to journalArticle

Open Access
File
Vitamin D
Blood Vessels
Meta-Analysis
Pulse Wave Analysis
Brachial Artery
4 Citations (Scopus)
115 Downloads (Pure)

Epicardial Adipose Tissue Is Related to Arterial Stiffness and Inflammation in Patients with Cardiovascular Disease and Type 2 Diabetes

Al-Talabany, S., Mordi, I., Houston, J. G., Colhoun, H. M., Weir-McCall, J. R., Matthew, S. Z., Looker, H. C., Levin, D., Belch, J. J. F., Dove, F., Khan, F. & Lang, C. C., 13 Feb 2018, In : BMC Cardiovascular Disorders. 18, p. 1-8 8 p., 31.

Research output: Contribution to journalArticle

Open Access
File
Arteritis
Vascular Stiffness
Type 2 Diabetes Mellitus
Adipose Tissue
Cardiovascular Diseases
2 Citations (Scopus)
136 Downloads (Pure)

In-vivo assessment of microvascular functional dynamics by combination of cmOCT and wavelet transform

Smirni, S., MacDonald, M. P., Robertson, C. P., McNamara, P. M., O'Gorman, S., Leahy, M. J. & Khan, F., 13 Feb 2018, Dynamics and Fluctuations in Biomedical Photonics XV. Tuchin, V. V., Larin, K. V., Leahy, M. J. & Wang, R. K. (eds.). Washington: SPIE-International Society for Optical Engineering, Vol. 10493. 12 p. 104930P

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
File
Wavelet Analysis
Optical tomography
Optical Coherence Tomography
wavelet analysis
Wavelet transforms
4 Citations (Scopus)
111 Downloads (Pure)
Open Access
File
Microvascular Angina
Natriuretic Peptides
Allopurinol
Exercise
Placebos
7 Citations (Scopus)
156 Downloads (Pure)

Use of Vascular Assessments and Novel Biomarkers to Predict Cardiovascular Events in Type 2 Diabetes: The SUMMIT VIP Study

SUMMIT Consortium, Shore, A. C., Colhoun, H. M., Natali, A., Palombo, C., Khan, F., Östling, G., Aizawa, K., Kennbäck, C., Casanova, F., Persson, M., Gooding, K., Gates, P. E., Looker, H., Dove, F., Belch, J., Pinnola, S., Venturi, E., Kozakova, M., Goncalves, I. & 3 others, Kravic, J., Björkbacka, H. & Nilsson, J., 1 Oct 2018, In : Diabetes Care. 41, 10, p. 2212-2219 8 p.

Research output: Contribution to journalArticle

Open Access
File
Type 2 Diabetes Mellitus
Blood Vessels
Cardiovascular Diseases
Biomarkers
Vascular Stiffness
2017
5 Citations (Scopus)
155 Downloads (Pure)

Effects of inaccuracies in arterial path length measurement on differences in MRI and tonometry measured pulse wave velocity

Weir-McCall, J. R., Khan, F., Cassidy, D. B., Thakur, A., Summersgill, J., Matthew, S. Z., Adams, F., Dove, F., Gandy, S. J., Colhoun, H. M., Belch, J. J. F. & Houston, J. G., 10 May 2017, In : BMC Cardiovascular Disorders. 17, p. 1-9 9 p., 118.

Research output: Contribution to journalArticle

Open Access
File
Pulse Wave Analysis
Manometry
Thigh
Angiography
Type 2 Diabetes Mellitus
13 Citations (Scopus)
175 Downloads (Pure)

ESVM guidelines: the diagnosis and management of Raynaud's phenomenon

Belch, J., Carlizza, A., Carpentier, P. H., Constans, J., Khan, F., Wautrecht, J-C., Visona, A., Heiss, C., Brodeman, M., Pécsvárady, Z., Roztocil, K., Colgan, M-P., Vasic, D., Gottsäter, A., Amann-Vesti, B., Chraim, A., Poredoš, P., Olinic, D-M., Madaric, J., Nikol, S. & 6 others, Herrick, A. L., Sprynger, M., Klein-Weigel, P., Hafner, F., Staub, D. & Zeman, Z., Oct 2017, In : VASA. 46, 6, p. 413-423 11 p.

Research output: Contribution to journalReview article

Open Access
File
Raynaud Disease
Guidelines
Terminology
Observational Studies
Epidemiologic Studies
153 Downloads (Pure)

Investigation of Ultrasound-Measured Flow Velocity, Flow Rate and Wall Shear Rate in Radial and Ulnar Arteries Using Simulation

Zhou, X., Xia, C., Gandy, S., Khan, F., Corner, G. A., Hoskins, P. R. & Huang, Z., May 2017, In : Ultrasound in Medicine and Biology. 43, 5, p. 981-992 12 p.

Research output: Contribution to journalArticle

Open Access
File
Ulnar Artery
Radial Artery
arteries
flow velocity
shear
9 Citations (Scopus)
117 Downloads (Pure)

The impact of cardiovascular co-morbidities and duration of diabetes on the association between microvascular function and glycaemic control

Casanova, F., Adingupu, D. D., Adams, F., Gooding, K. M., Looker, H. C., Aizawa, K., Dove, F., Elyas, S., Belch, J. J. F., Gates, P. E., Littleford, R. C., Gilchrist, M., Colhoun, H. M., Shore, A. C., Khan, F. & Strain, W. D., 15 Sep 2017, In : Cardiovascular Diabetology. 16, p. 1-11 11 p., 114.

Research output: Contribution to journalArticle

Open Access
File
Single Nucleotide Polymorphism
Morbidity
Cardiovascular Models
Microcirculation
Hyperglycemia
2016
1 Citation (Scopus)

Acute risk factors in fatal opioid overdoses as a result of hypoxia and cardiotoxicity. A systematic review and critical appraisal

Baldacchino, A., Tolomeo, S., Khan, F., Humphris, G. & Carrà, G., Aug 2016, In : Heroin Addiction and Related Clinical Problems. 18, 4, p. 33-42 10 p.

Research output: Contribution to journalReview article

Opioid Analgesics
Vascular Stiffness
Poisons
Cardiotoxicity
Hypoxia
7 Citations (Scopus)
125 Downloads (Pure)

Association between GDF-15 levels and changes in vascular and physical function in older patients with hypertension

Barma, M., Khan, F., Price, R. J. G., Donnan, P. T., Messow, C. M., Ford, I., McConnachie, A., Struthers, A. D., McMurdo, M. E. T. & Witham, M. D., 2016, In : Aging Clinical and Experimental Research. 29, 5, p. 1055-1059 5 p.

Research output: Contribution to journalArticle

Open Access
File
Growth Differentiation Factor 15
Blood Vessels
Hypertension
Population
Walking
2 Citations (Scopus)
132 Downloads (Pure)

Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes

Gonçalves, I., Edsfeldt, A., Colhoun, H. M., Shore, A. C., Palombo, C., Natali, A., Fredrikson, G. N., Björkbacka, H., Wigren, M., Bengtsson, E., Östling, G., Aizawa, K., Casanova, F., Persson, M., Gooding, K., Gates, P., Khan, F., Looker, H. C., Adams, F., Belch, J. & 7 others, Pinnola, S., Venturi, E., Kozakova, M., Gan, L-M., Schnecke, V., Nilsson, J. & SUMMIT Consortium, 5 Sep 2016, In : BMC Cardiovascular Disorders. 16, p. 1-10 10 p., 171.

Research output: Contribution to journalArticle

Open Access
File
Renin
Type 2 Diabetes Mellitus
Blood Vessels
Renin-Angiotensin System
Carotid Intima-Media Thickness
1 Citation (Scopus)

Can antioxidant-rich blackcurrant juice drink consumption improve photoprotection against ultraviolet radiation?

Ray, S., Belch, J. J., Craigie, A. M., Khan, F., Kennedy, G., Hill, A., Barton, K. L., Dawe, R. S. & Ibbotson, S. H., May 2016, In : British Journal of Dermatology. 174, 5, p. 1101-1103 3 p.

Research output: Contribution to journalLetter

14 Citations (Scopus)

Effect of vitamin K on vascular health and physical function in older people with vascular disease–a randomised controlled trial

Fulton, R. L., McMurdo, M. E. T., Hill, A., Abboud, R. J., Arnold, G. P., Struthers, A. D., Khan, F., Vermeer, C., Knapen, M. H. J., Drummen, N. E. A. & Witham, M. D., Mar 2016, In : Journal of Nutrition Health & Aging. 20, 3, p. 325-333 9 p.

Research output: Contribution to journalArticle

Vitamin K
Blood Vessels
Randomized Controlled Trials
Vascular Diseases
Placebos

Epicardial Adipose Tissue is Related to Arterial Stiffness in Patients with Cardio-metabolic Disease

Al-Talabany, S., Khan, F., Houston, G., Colhoun, H., Weir-Mccall, J., Leven, D., Dove, F., Cassidy, D., Looker, H. & Lang, C., 5 Apr 2016, In : Journal of the American College of Cardiology. 67, 13, Supplement 5, p. 1832 1 p., 1263-258.

Research output: Contribution to journalArticle

Vascular Stiffness
Metabolic Diseases
Adipose Tissue
Type 2 Diabetes Mellitus
Cardiovascular Diseases
1 Citation (Scopus)
95 Downloads (Pure)

Follow-up of atheroma burden with sequential whole body contrast enhanced MR angiography: a feasibility study

Weir-McCall, J., White, R. D., Ramkumar, P. G., Gandy, S. J., Khan, F., Belch, J. J. F., Struthers, A. D. & Houston, J. G., May 2016, In : International Journal of Cardiovascular Imaging. 32, 5, p. 825-832 8 p.

Research output: Contribution to journalArticle

Open Access
File
Feasibility Studies
Atherosclerotic Plaques
Angiography
Magnetic Resonance Angiography
Peripheral Arterial Disease
6 Citations (Scopus)
148 Downloads (Pure)

Investigation of Ultrasound-Measured Flow Rate and Wall Shear Rate in Wrist Arteries Using Flow Phantoms

Zhou, X., Xia, C., Khan, F., Corner, G. A., Huang, Z. & Hoskins, P. R., Mar 2016, In : Ultrasound in Medicine and Biology. 42, 3, p. 815-823 9 p.

Research output: Contribution to journalArticle

Open Access
File
Ulnar Artery
wrist
Radial Artery
arteries
Wrist

In vivo inhibition of nuclear factor of activated t cells (NFAT) restores microvascular endothelial function in diabetic mice

Garcia-Vaz, E., McNeilly, A., Gallagher, J., McCrimmon, R., Khan, F. & Gomez, M. F., Sep 2016, In : Atherosclerosis. 252, p. e244-e245 2 p., EAS16-0988.

Research output: Contribution to journalArticle

A 285222
Diabetic Angiopathies
Luciferases
Acetylcholine
Blood Glucose
1 Citation (Scopus)
162 Downloads (Pure)

Whole body cardiovascular MRI for the comparison of atherosclerotic burden and cardiac remodelling in healthy South Asian and European adults

Weir-McCall, J., Cassidy, D. B., Belch, J. J. F., Gandy, S. J., Houston, J. G., Lambert, M. A., Littleford, R. C., Rowland, J., Struthers, A. D. & Khan, F., 2016, In : British Journal of Radiology. 89, 1065, p. 1-8 8 p., 20150887.

Research output: Contribution to journalArticle

Open Access
File
Cardiovascular Diseases
Atherosclerotic Plaques
Angiography
Peripheral Arterial Disease
Gadolinium