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  • James Chalmers
Article

A comprehensive approach to lung function in bronchiectasis

Radovanovic, D., Santus, P., Blasi, F., Sotgiu, G., D'Arcangelo, F., Simonetta, E., Contarini, M., Franceschi, E., Goeminne, P. C., Chalmers, J. D. & Aliberti, S., Dec 2018, In : Respiratory Medicine. 145, p. 120-129 10 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
104 Downloads (Pure)

Airway Mucin 2 is decreased in patients with severe chronic obstructive pulmonary disease with bacterial colonization

Sibila, O., Garcia-Bellmunt, L., Giner, J., Rodrigo-Troyano, A., Suarez-Cuartin, G., Torrego, A., Castillo, D., Solanes, I., Mateus, E. F., Vidal, S., Sanchez-Reus, F., Sala, E., Cosio, B. G., Restrepo, M. I., Anzueto, A., Chalmers, J. D. & Plaza, V., 1 May 2016, In : Annals of the American Thoracic Society. 13, 5, p. 636-642 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Anti-Pseudomonas aeruginosa IgG antibodies and chronic airway infection in bronchiectasis

Suarez-Cuartin, G., Smith, A., Abo-Leyah, H., Rodrigo-Troyano, A., Perea, L., Vidal, S., Plaza, V., Fardon, T. C., Sibila, O. & Chalmers, J. D., Jul 2017, In : Respiratory Medicine. 128, p. 1-6 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

A randomised control trial of atorvastatin in bronchiectasis patients infected with Pseudomonas aeruginosa- a proof of concept study

Bedi, P., Chalmers, J. D., Graham, C., Clarke, A., Donaldson, S., Doherty, C. J., Govan, J. R. W., Davidson, D. J., Rossi, A. G. & Hill, A. T., Aug 2017, In : Chest. 152, 2, p. 368-378 11 p.

Research output: Contribution to journalArticle

Open Access
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19 Citations (Scopus)
139 Downloads (Pure)
Open Access
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4 Citations (Scopus)
162 Downloads (Pure)

A systematic review of the burden of vaccine preventable pneumococcal disease in UK adults

Chalmers, J. D., Dicker, A., Woodhead, M. & Madhava, H., 11 May 2016, In : BMC Pulmonary Medicine. 16, 1, p. 1-11 11 p., 77.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
189 Downloads (Pure)

British Thoracic Society guideline for bronchiectasis in adults

Hill, A. T., Sullivan, A. L., Chalmers, J. D., De Soyza, A., Elborn, J. S., Floto, R. A., Grillo, L., Gruffydd-Jones, K., Harvey, A., Haworth, C. S., Hiscocks, E., Hurst, J. R., Johnson, C., Kelleher, W. P., Bedi, P., Payne, K., Saleh, H., Screaton, N. J., Smith, M., Tunney, M. & 3 others, Whitters, D., Wilson, R. & Loebinger, M. R., 1 Dec 2018, In : BMJ Open Respiratory Research. 5, 1, 16 p., e000348.

Research output: Contribution to journalArticle

Open Access
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3 Citations (Scopus)
119 Downloads (Pure)

Bronchiectasis: Phenotyping a Complex Disease

Chalmers, J. D., 17 Mar 2017, In : COPD. 14, Suppl.1, p. S12-S18 7 p.

Research output: Contribution to journalArticle

Open Access
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6 Citations (Scopus)
144 Downloads (Pure)

Bronchiectasis: a case-based approach to investigation and management

Contarini, M., Finch, S. & Chalmers, J. D., 30 Sep 2018, In : European Respiratory Review. 27, 149, p. 1-13 13 p., 180016.

Research output: Contribution to journalArticle

Open Access
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9 Citations (Scopus)
125 Downloads (Pure)

Bronchiectasis Rheumatoid Overlap Syndrome Is an Independent Risk Factor for Mortality in Patients With Bronchiectasis: A Multicenter Cohort Study

De Soyza, A., McDonnell, M. J., Goeminne, P. C., Aliberti, S., Lonni, S., Davison, J., Dupont, L. J., Fardon, T. C., Rutherford, R. M., Hill, A. T. & Chalmers, J. D., Jun 2017, In : Chest. 151, 6, p. 1247-1254 8 p.

Research output: Contribution to journalArticle

Open Access
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31 Citations (Scopus)
169 Downloads (Pure)

Burden and risk factors for Pseudomonas aeruginosa community-acquired pneumonia: a Multinational Point Prevalence Study of Hospitalised Patients

Restrepo, M. I., Babu, B. L., Reyes, L. F., Chalmers, J. D., Soni, N. J., Sibila, O., Faverio, P., Cilloniz, C., Rodriguez-Cintron, W. & Aliberti, S., 9 Aug 2018, In : European Respiratory Journal. 52, 2, 1701190.

Research output: Contribution to journalArticle

Open Access
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16 Citations (Scopus)
46 Downloads (Pure)

Cardiovascular disease as a complication of community-acquired pneumonia

Rae, N., Finch, S. & Chalmers, J. D., May 2016, In : Current Opinion in Pulmonary Medicine. 22, 3, p. 212-218 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Characterization of bronchiectasis in the elderly

Bellelli, G., Chalmers, J. D., Sotgiu, G., Dore, S., McDonnell, M. J., Goeminne, P. C., Dimakou, K., Skrbic, D., Lombi, A., Pane, F., Obradovic, D., Fardon, T. C., Rutherford, R. M., Pesci, A. & Aliberti, S., Oct 2016, In : Respiratory Medicine. 119, p. 13-19 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
261 Downloads (Pure)

Characterization of the “frequent exacerbator phenotype” in bronchiectasis

Chalmers, J. D., Aliberti, S., Filonenko, A., Shteinberg, M., Goeminne, P. C., Hill, A. T., Fardon, T. C., Obradovic, D., Gerlinger, C., Sotgiu, G., Operschall, E., Rutherford, R. M., Dimakou, K., Polverino, E., De Soyza, A. & McDonnell, M. J., 1 Jun 2018, In : American Journal of Respiratory and Critical Care Medicine. 197, 11, p. 1410-1420 11 p.

Research output: Contribution to journalArticle

Open Access
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63 Citations (Scopus)
152 Downloads (Pure)

Characterizing non-tuberculous mycobacteria infection in bronchiectasis

Faverio, P., Stainer, A., Bonaiti, G., Zucchetti, S. C., Simonetta, E., Lapadula, G., Marruchella, A., Gori, A., Blasi, F., Codecasa, L., Pesci, A., Chalmers, J. D., Loebinger, M. R. & Aliberti, S., 16 Nov 2016, In : International Journal of Molecular Sciences. 17, 11, 12 p., 1913.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
127 Downloads (Pure)

Circulating desmosine as a biomarker of azithromycin treatment response: a post hoc analysis of the COLUMBUS randomised controlled trial

Chalmers, J. D., Djamin, R. S., Schouten, M., Keir, H. R., Tan, B., Aerts, J. G. J. V., Huang, J. T-J. & van der Eerden, M., Oct 2018, In : ERJ Open Research. 4, 4, p. 1-4 4 p.

Research output: Contribution to journalArticle

Open Access
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95 Downloads (Pure)

Clinical phenotypes in adult patients with bronchiectasis

Aliberti, S., Lonni, S., Dore, S., McDonnell, M. J., Goeminne, P. C., Dimakou, K., Fardon, T., Rutherford, R., Pesci, A., Restrepo, M. I., Sotgiu, G. & Chalmers, J., 1 Apr 2016, In : European Respiratory Journal. 47, 4, p. 1113-1122 10 p.

Research output: Contribution to journalArticle

Open Access
File
122 Citations (Scopus)
133 Downloads (Pure)

Community-acquired pneumonia related to intracellular pathogens

Cillóniz, C., Torres, A., Niederman, M., van der Eerden, M., Chalmers, J., Welte, T. & Blasi, F., Sep 2016, In : Intensive Care Medicine. 42, 9, p. 1374-1386 13 p.

Research output: Contribution to journalArticle

Open Access
File
28 Citations (Scopus)
354 Downloads (Pure)

Comorbidities and the risk of mortality in patients with bronchiectasis: an international mulitcentre cohort study

McDonnell, M. J., Aliberti, S., Goeminne, P. C., Restrepo, M. I., Finch, S., Pesci, A., Dupont, L., Fardon, T., Wilson, R., Loebinger, M., Skrbic, D., Obradovic, D., De Soyza, A., Ward, C., Laffey, J. G., Rutherford, R. & Chalmers, J., Dec 2016, In : The Lancet Respiratory Medicine. 4, 12, p. 969-979 11 p.

Research output: Contribution to journalArticle

Open Access
File
81 Citations (Scopus)
145 Downloads (Pure)

Continuous versus intermittent antibiotics for non-cystic fibrosis bronchiectasis

Donovan, T., Felix, L. M., Chalmers, J. D., Milan, S. J., Mathioudakis, A. G. & Spencer, S., 26 Jul 2017, In : Cochrane Database of Systematic Reviews. 2017, 7, p. 1-13 13 p., CD012733.

Research output: Contribution to journalArticle

Open Access
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92 Downloads (Pure)

Cross-infection risk in patients with bronchiectasis: a position statement from the European Bronchiectasis Network (EMBARC), EMBARC/ELF patient advisory group and European Reference Network (ERN-Lung) Bronchiectasis Network

Chalmers, J. D., Ringshausen, F. C., Harris, B., Elborn, J. S., Posthumus, A., Haworth, C. S., Pilkington, N., Polverino, E., Ruddy, T., Aliberti, S., Goeminne, P. C., Winstanley, C. & De Soyza, A., 1 Jan 2018, In : European Respiratory Journal. 51, 1, 6 p., 1701937.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
80 Downloads (Pure)

Determinants of initial inhaled corticosteroid use in patients with GOLD A/B COPD: a retrospective study of UK general practice

Chalmers, J. D., Tebboth, A., Gayle, A., Ternouth, A. & Ramscar, N., 29 Jun 2017, In : NPJ Primary Care Respiratory Medicine. 27, p. 1-8 8 p., 43.

Research output: Contribution to journalArticle

Open Access
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23 Citations (Scopus)
162 Downloads (Pure)

Development and initial validation of the bronchiectasis exacerbation and symptom tool (BEST)

Artaraz, A., Crichton, M. L., Finch, S., Abo-Leyah, H., Goeminne, P., Aliberti, S., Fardon, T. & Chalmers, J. D., 13 Jan 2020, In : Respiratory Research. 21, 1, p. 1-9 1 p., 18.

Research output: Contribution to journalArticle

Open Access
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35 Downloads (Pure)

Development and Reporting of Prediction Models: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals

Leisman, D. E., Harhay, M. O., Lederer, D. J., Abramson, M., Adjei, A. A., Bakker, J., Ballas, Z. K., Barreiro, E., Bell, S. C., Bellomo, R., Bernstein, J. A., Branson, R. D., Brusasco, V., Chalmers, J. D., Chokroverty, S., Citerio, G., Collop, N. A., Cooke, C. R., Crapo, J. D., Donaldson, G. & 19 others, Fitzgerald, D. A., Grainger, E., Hale, L., Herth, F. J., Kochanek, P. M., Marks, G., Moorman, J. R., Ost, D. E., Schatz, M., Sheikh, A., Smyth, A. R., Stewart, I., Stewart, P. W., Swenson, E. R., Szymusiak, R., Teboul, J-L., Vincent, J-L., Wedzicha, J. A. & Maslove, D. M., May 2020, In : Critical Care Medicine. 48, 5, p. 623-633 11 p.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
139 Downloads (Pure)

Economic burden of bronchiectasis in Germany

Diel, R., Chalmers, J. D., Rabe, K. F., Nienhaus, A., Loddenkemper, R. & Ringshausen, F. C., 5 Dec 2018, In : European Respiratory Journal.

Research output: Contribution to journalArticle

Endothelial adhesion molecules and multiple organ failure in patients with severe sepsis

Amalakuhan, B., Habib, S. A., Mangat, M., Reyes, L. F., Rodriguez, A. H., Hinojosa, C. A., Soni, N. J., Gilley, R. P., Bustamante, C. A., Anzueto, A., Levine, S. M., Peters, J. I., Aliberti, S., Sibila, O., Chalmers, J. D., Torres, A., Waterer, G. W., Martin-Loeches, I., Bordon, J., Blanquer, J. & 15 others, Sanz, F., Marcos, P. J., Rello, J., Ramirez, J., Solé-Violán, J., Luna, C. M., Feldman, C., Witzenrath, M., Wunderink, R. G., Stolz, D., Wiemken, T. L., Shindo, Y., Dela Cruz, C. S., Orihuela, C. J. & Restrepo, M. I., Dec 2016, In : Cytokine. 88, p. 267-273 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
113 Downloads (Pure)

European Respiratory Society guidelines for the management of adult bronchiectasis

Polverino, E., Goeminne, P. C., McDonnell, M. J., Aliberti, S., Marshall, S. E., Loebinger, M. R., Murris-Espin, M., Cantón, R., Torres, A., Dimakou, K., De Soyza, A., Hill, A. T., Haworth, C. S., Vendrell, M., Ringshausen, F. C., Subotic, D., Wilson, R., Vilaró, J., Stallberg, B., Welte, T. & 9 others, Rohde, G., Blasi, F., Elborn, J. S., Almagro, M., Timothy, A., Ruddy, T., Tonia, T., Rigau, D. & Chalmers, J. D., Sep 2017, In : European Respiratory Journal. 50, 3, p. 1-23 23 p., 1700629.

Research output: Contribution to journalArticle

Open Access
File
229 Citations (Scopus)
194 Downloads (Pure)

Evaluation of serum inflammatory biomarkers as predictors of treatment outcome in pulmonary tuberculosis

Singanayagam, A., Manalan, K., Connell, D. W., Chalmers, J. D., Sridhar, S., Ritchie, A. I., Lalvani, A., Wickremasinghe, M. & Kon, O. M., 1 Dec 2016, In : International Journal of Tuberculosis and Lung Disease. 20, 12, p. 1653-1660 8 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
137 Downloads (Pure)

Evaluation of severity score-guided approaches to macrolide use in community-acquired pneumonia

Singanayagam, A., Aliberti, S., Cillóniz, C., Torres, A., Blasi, F. & Chalmers, J. D., Sep 2017, In : European Respiratory Journal. 50, 3, 1602306.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
169 Downloads (Pure)

Genetic mannose binding lectin deficiency is associated with airway microbiota diversity and reduced exacerbation frequency in COPD

Dicker, A. J., Crichton, M. L., Cassidy, A. J., Brady, G., Hapca, A., Tavendale, R., Einarsson, G. G., Furrie, E., Elborn, J. S., Schembri, S., Marshall, S. E., Palmer, C. N. A. & Chalmers, J. D., Jun 2018, In : Thorax. 73, 6, p. 510-518 9 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
146 Downloads (Pure)

How to Process Sputum Samples and Extract Bacterial DNA for Microbiota Analysis

Terranova, L., Oriano, M., Teri, A., Ruggiero, L., Tafuro, C., Marchisio, P., Gramegna, A., Contarini, M., Franceschi, E., Sottotetti, S., Cariani, L., Bevivino, A., Chalmers, J. D., Aliberti, S. & Blasi, F., 20 Oct 2018, In : International Journal of Molecular Sciences. 19, 10, p. 1-12 12 p., 3256.

Research output: Contribution to journalArticle

Open Access
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3 Citations (Scopus)
109 Downloads (Pure)

Identification of Pseudomonas aeruginosa and airway bacterial colonization by an electronic nose in bronchiectasis

Suarez-Cuartin, G., Giner, J., Merino, J. L., Rodrigo-Troyano, A., Feliu, A., Perea, L., Sanchez-Reus, F., Castillo, D., Plaza, V., Chalmers, J. D. & Sibila, O., 1 Mar 2018, In : Respiratory Medicine. 136, p. 111-117 7 p.

Research output: Contribution to journalArticle

Open Access
File
139 Downloads (Pure)

Immunological corollary of the pulmonary mycobiome in bronchiectasis: The Cameb study

Mac Aogáin, M., Chandrasekaran, R., Lim Yick Hou, A., Teck Boon, L., Liang Tan, G., Hassan, T., Thun How, O., Hui Qi Ng, A., Bertrand, D., Yu Koh, J., Lei Pang, S., Yang Lee, Z., Wei Gwee, X., Martinus, C., Yie Sio, Y., Anusha Matta, S., Tim Chew, F., Keir, H. R., Connolly, J. E., Arputhan Abisheganaden, J. & 4 others, Siyue Koh, M., Nagarajan, N., Chalmers, J. D. & Chotirmall, S. H., Jul 2018, In : European Respiratory Journal. 52, 1, p. 1-14 14 p., 1800766.

Research output: Contribution to journalArticle

Open Access
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24 Citations (Scopus)
156 Downloads (Pure)

Increased Chitotriosidase is Associated with Aspergillus and Frequent Exacerbations in South-East Asians with Bronchiectasis

Poh, T. Y., Tiew, P. Y., Hou Lim, A. Y., Thng, K. X., Binte Mohamed Ali, N. A., Narayana, J. K., Aogáin, M. M., Tien, Z., Chew, W. M., Wai Chan, A. K., Keir, H. R., Dicker, A. J., Hassan, T. M., Xu, H., Tee, A. K. H., Ong, T. H., Koh, M. S., Abisheganaden, J. A., Chalmers, J. D. & Chotirmall, S. H., 14 Mar 2020, In : Chest.

Research output: Contribution to journalArticle

Is bronchiectasis really a disease?

Shteinberg, M., Flume, P. A. & Chalmers, J. D., 31 Mar 2020, In : European Respiratory Review. 29, 155, p. 1-10 10 p., 190051.

Research output: Contribution to journalArticle

Open Access
File
30 Downloads (Pure)

Macrolide therapy is associated with lower mortality in community-acquired bacteraemic pneumonia

Jul 2018, In : Respiratory Medicine. 140, p. 115-121 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Management of chronic airway diseases: What can we learn from real-life data?

Chalmers, J. D., 17 Mar 2017, In : COPD. 14, Suppl. 1, p. S1-S2 2 p.

Research output: Contribution to journalArticle

Open Access
File
187 Downloads (Pure)

Managing and preventing exacerbation of bronchiectasis

Abo-Leyah, H. & Chalmers, J. D., Apr 2020, In : Current Opinion in Infectious Diseases. 33, 2, p. 189-196 8 p.

Research output: Contribution to journalArticle

Multidimensional severity assessment in bronchiectasis: An analysis of 7 European cohorts.

McDonnell, M. J., Alberti, S., Goeminne, P. C., Dimakou, K., Davidson, J., Ward, C., LAffey, JG., Finch, S., Pesci, A., Dupont, LJ., Fardon, T. C., Skrbic, D., Obradovic, D., Cowman, S., Loebinger, M. R., Rutherford, RM., De Soyza, A. & Chalmers, J. D., Dec 2016, In : Thorax. 71, 12, p. 1110-1118 9 p.

Research output: Contribution to journalArticle

Open Access
File
69 Citations (Scopus)
143 Downloads (Pure)

Neutrophil elastase activity is associated with exacerbations and lung function decline in Bronchiectasis

Chalmers, J. D., Moffitt, K. L., Suarez-Cuartin, G., Sibila, O., Finch, S., Furrie, E., Dicker, A., Wrobel, K., Elborn, J. S., Walker, B., Martin, S. L., Marshall, S. E., Huang, J. T-J. & Fardon, T. C., 15 May 2017, In : American Journal of Respiratory and Critical Care Medicine. 195, 10, p. 1384-1393 10 p.

Research output: Contribution to journalArticle

Open Access
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80 Citations (Scopus)
136 Downloads (Pure)

Neutrophil extracellular traps are associated with disease severity and microbiota diversity in patients with chronic obstructive pulmonary disease

Dicker, A. J., Crichton, M. L., Pumphrey, E. G., Cassidy, A. J., Suarez-Cuartin, G., Sibila, O., Furrie, E., Fong, C. J., Ibrahim, W., Brady, G., Einarsson, G. G., Elborn, J. S., Schembri, S., Marshall, S. E., Palmer, C. N. A. & Chalmers, J. D., Jan 2018, In : Journal of Allergy and Clinical Immunology. 141, 1, p. 117-127 11 p.

Research output: Contribution to journalArticle

Open Access
File
61 Citations (Scopus)
126 Downloads (Pure)

Oral versus intravenous clarithromycin in moderate to severe community-acquired pneumonia: an observational study

Rae, N., Singanayagam, A., Schembri, S. & Chalmers, J. D., 5 Feb 2017, In : Pneumonia . 9, p. 1-5 5 p., 2.

Research output: Contribution to journalArticle

Open Access
File
155 Downloads (Pure)
4 Citations (Scopus)

Pseudomonas aeruginosa resistance patterns and clinical outcomes in hospitalized exacerbations of COPD

Rodrigo-Troyano, A., Suarez-Cuartin, G., Peiró, M., Barril, S., Castillo, D., Sanchez-Reus, F., Plaza, V., Restrepo, M. I., Chalmers, J. D. & Sibila, O., Oct 2016, In : Respirology . 21, 7, p. 1235-1242 8 p.

Research output: Contribution to journalArticle

Open Access
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20 Citations (Scopus)
154 Downloads (Pure)

Pulmonary exacerbation in adults with bronchiectasis: a consensus definition for clinical research

Hill, A. T., Haworth, C. S., Aliberti, S., Barker, A., Blasi, F., Boersma, W., Chalmers, J. D., De Soyza, A., Dimakou, K., Elborn, J. S., Feldman, C., Flume, P., Goeminne, P. C., Loebinger, M. R., Menendez, R., Morgan, L., Murris-Espin, M., Polverino, E., Quittner, A., Ringshausen, F. C. & 9 others, Tino, G., Torres, A., Vendrell, M., Welte, T., Wilson, R., Wong, C., O'Donnell, A., Aksamit, T. & for the EMBARC/BRR definitions working group, 1 Jun 2017, In : European Respiratory Journal. 49, 6, 8 p., 1700051.

Research output: Contribution to journalArticle

Open Access
80 Citations (Scopus)

Quality control for multiple breath washout tests in multicentre bronchiectasis studies: Experiences from the BRONCH-UK clinimetrics study

O'Neill, K., Lakshmipathy, G. R., Ferguson, K., Cosgrove, D., Hill, A. T., Loebinger, M., Carroll, M., Chalmers, J., Gatheral, T., Johnson, C., DeSoyza, A., Hurst, J. R., Bradbury, I., Elborn, J. S. & Bradley, J. M., Dec 2018, In : Respiratory Medicine. 145, p. 206-211 6 p.

Research output: Contribution to journalArticle

Open Access
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57 Downloads (Pure)

Quality standards for the management of bronchiectasis in Italy: a national audit

SIP Bronchiectasis Audit Working Group, Aliberti, S., Hill, A. T., Mantero, M., Battaglia, S., Centanni, S., Lo Cicero, S., Lacedonia, D., Saetta, M., Chalmers, J. D. & Blasi, F., 30 Jun 2016, In : European Respiratory Journal. 48, 1, p. 244-248 5 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Research priorities in bronchiectasis: a consensus statement from the EMBARC Clinical Research Collaboration

Aliberti, S., Masefield, S., Polverino, E., De Soyza, A., Loebinger, M. R., Menendez, R., Ringshausen, F. C., Vendrell, M., Powell, P., Chalmers, J. D. &  on behalf of the EMBARC Study Group, 1 Sep 2016, In : European Respiratory Journal. 48, 3, p. 632-647 16 p.

Research output: Contribution to journalArticle

Open Access
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83 Citations (Scopus)
204 Downloads (Pure)