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  • James Chalmers

10 years since TORCH: shining a new light on the risks of inhaled corticosteroids in COPD

Chalmers, J. D. & Keir, H. R., 1 Sep 2017, In : European Respiratory Journal. 50, 3, 5 p., 1701582.

Research output: Contribution to journalEditorial

3 Citations (Scopus)

A 2 × 2 factorial, randomised, open-label trial to determine the clinical and cost-effectiveness of hypertonic saline (HTS 6%) and carbocisteine for airway clearance versus usual care over 52 weeks in adults with bronchiectasis: a protocol for the CLEAR clinical trial

Bradley, J. M., Anand, R., O'Neill, B., Ferguson, K., Clarke, M., Carroll, M., Chalmers, J., De Soyza, A., Duckers, J., Hill, A. T., Loebinger, M. R., Copeland, F., Gardner, E., Campbell, C., Agus, A., McGuire, A., Boyle, R., McKinney, F., Dickson, N., McAuley, D. F. & 1 others, Elborn, S., 19 Dec 2019, In : Trials. 20, 1, p. 1-10 10 p., 747.

Research output: Contribution to journalArticle

Open Access
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37 Downloads (Pure)

ACCORD: A Multicentre, Seamless, Phase 2 Adaptive Randomisation Platform Study to Assess the Efficacy and Safety of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalised Patients: A structured summary of a study protocol for a randomised controlled trial

Wilkinson, T., Dixon, R., Page, C., Carroll, M., Griffiths, G., Ho, L-P., De Soyza, A., Felton, T., Lewis, K. E., Phekoo, K., Chalmers, J. D., Gordon, A., McGarvey, L., Doherty, J., Read, R. C., Shankar-Hari, M., Martinez-Alier, N., O'Kelly, M., Duncan, G., Walles, R. & 3 others, Sykes, J., Summers, C. & Singh, D., 31 Jul 2020, In : Trials. 21, 1, 3 p., 691.

Research output: Contribution to journalArticle

Open Access
File

Additional important research priorities for bronchiectasis in China

Aliberti, S., Dhar, R., Aksamit, T. R., Morgan, L. & Chalmers, J. D., 1 Jan 2017, In : European Respiratory Journal. 49, 1, 1602317.

Research output: Contribution to journalLetter

Open Access
File
156 Downloads (Pure)

Airway Bacterial Load and Inhaled Antibiotic Response in Bronchiectasis

Sibila, O., Laserna, E., Shoemark, A., Keir, H. R., Finch, S., Rodrigo-Troyano, A., Perea, L., Lonergan, M., Goeminne, P. C. & Chalmers, J. D., 1 Jul 2019, In : American Journal of Respiratory and Critical Care Medicine. 200, 1, p. 33-41 9 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
15 Downloads (Pure)

Airway Mucin 2 is decreased in patients with severe chronic obstructive pulmonary disease with bacterial colonization

Sibila, O., Garcia-Bellmunt, L., Giner, J., Rodrigo-Troyano, A., Suarez-Cuartin, G., Torrego, A., Castillo, D., Solanes, I., Mateus, E. F., Vidal, S., Sanchez-Reus, F., Sala, E., Cosio, B. G., Restrepo, M. I., Anzueto, A., Chalmers, J. D. & Plaza, V., 1 May 2016, In : Annals of the American Thoracic Society. 13, 5, p. 636-642 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

A new free-cost e-service supporting clinicians to manage their difficult-to-treat tuberculosis cases: The European Respiratory Society-World Health Organization tuberculosis Consilium

D'Ambrosio, L., Tadolini, M., Centis, R., Chalmers, J. D. & Migliori, G. B., 27 Jul 2017, In : Indian Journal of Medical Research. 145, 3, p. 261-263 3 p.

Research output: Contribution to journalEditorial

Open Access
File
20 Downloads (Pure)

Antimicrobial peptides, disease severity and exacerbations in bronchiectasis

Sibila, O., Perea, L., Cantó, E., Shoemark, A., Cassidy, D., Smith, A. H., Suarez-cuartin, G., Rodrigo-troyano, A., Keir, H. R., Oriano, M., Ong, S., Vidal, S., Blasi, F., Aliberti, S. & Chalmers, J. D., Sep 2019, In : Thorax. 74, 9, p. 835-842 8 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
179 Downloads (Pure)

Anti-Pseudomonas aeruginosa IgG antibodies and chronic airway infection in bronchiectasis

Suarez-Cuartin, G., Smith, A., Abo-Leyah, H., Rodrigo-Troyano, A., Perea, L., Vidal, S., Plaza, V., Fardon, T. C., Sibila, O. & Chalmers, J. D., Jul 2017, In : Respiratory Medicine. 128, p. 1-6 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

A point of care neutrophil elastase activity assay identifies bronchiectasis severity, airway infection and risk of exacerbation

Shoemark, A., Cant, E., Carreto, L., Smith, A., Oriano, M., Keir, H. R., Perea, L., Canto, E., Terranova, L., Vidal, S., Moffitt, K., Aliberti, S., Sibila, O. & Chalmers, J. D., 1 Jun 2019, In : European Respiratory Journal. 53, 6, 1900303.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
11 Downloads (Pure)

A randomised control trial of atorvastatin in bronchiectasis patients infected with Pseudomonas aeruginosa- a proof of concept study

Bedi, P., Chalmers, J. D., Graham, C., Clarke, A., Donaldson, S., Doherty, C. J., Govan, J. R. W., Davidson, D. J., Rossi, A. G. & Hill, A. T., Aug 2017, In : Chest. 152, 2, p. 368-378 11 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
148 Downloads (Pure)

A systematic review of pharmacotherapeutic clinical trial end-points for bronchiectasis in adults

Crichton, M. L., Aliberti, S. & Chalmers, J. D., 31 Mar 2019, In : European Respiratory Review. 28, 151, p. 1-14 14 p., 180108.

Research output: Contribution to journalReview article

Open Access
File
3 Citations (Scopus)
132 Downloads (Pure)

A systematic review of the burden of vaccine preventable pneumococcal disease in UK adults

Chalmers, J. D., Dicker, A., Woodhead, M. & Madhava, H., 11 May 2016, In : BMC Pulmonary Medicine. 16, 1, p. 1-11 11 p., 77.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
200 Downloads (Pure)

Blood neutrophil counts are associated with exacerbation frequency and mortality in COPD

Lonergan, M., Dicker, A. J., Crichton, M. L., Keir, H. R., Van Dyke, M. K., Mullerova, H., Miller, B. E., Tal-Singer, R. & Chalmers, J. D., 1 Jul 2020, In : Respiratory Research. 21, p. 1-10 10 p., 166.

Research output: Contribution to journalArticle

Open Access
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7 Downloads (Pure)

British Thoracic Society Guideline for bronchiectasis in adults

Hill, A. T., Sullivan, A. L., Chalmers, J. D., De Soyza, A., Elborn, J. S., Floto, R. A., Grillo, L., Gruffydd-Jones, K., Harvey, A., Haworth, C. S., Hiscocks, E., Hurst, J. R., Johnson, C., Kelleher, W. P., Bedi, P., Payne, K., Saleh, H., Screaton, N. J., Smith, M., Tunney, M. & 3 others, Whitters, D., Wilson, R. & Loebinger, M. R., Jan 2019, In : Thorax. 74, Suppl 1, p. 1-69 69 p., 74.

Research output: Contribution to journalArticle

Open Access
File
41 Citations (Scopus)
100 Downloads (Pure)

Bronchiectasis: Phenotyping a Complex Disease

Chalmers, J. D., 17 Mar 2017, In : COPD. 14, Suppl.1, p. S12-S18 7 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
153 Downloads (Pure)

Bronchiectasis and COPD Overlap: A Case of Mistaken Identity?

Chalmers, J. D., Jun 2017, In : Chest. 151, 6, p. 1204-1206 3 p.

Research output: Contribution to journalEditorial

11 Citations (Scopus)

Bronchiectasis in India: results from the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) and Respiratory Research Network of India Registry

Dhar, R., Singh, S., Talwar, D., Mohan, M., Tripathi, S. K., Swarnakar, R., Trivedi, S., Rajagopala, S., D'Souza, G., Padmanabhan, A., Baburao, A., Mahesh, P. A., Ghewade, B., Nair, G., Jindal, A., Jayadevappa, G. D. H., Sawhney, H., Sarmah, K. R., Saha, K., Anantharaj, S. & 44 others, Khanna, A., Gami, S., Shah, A., Shah, A., Dutt, N., Garg, H., Vyas, S., Venugopal, K., Prasad, R., Aleemuddin, N. M., Karmakar, S., Singh, V., Jindal, S. K., Sharma, S., Prajapat, D., Chandrashekaria, S., McDonnell, M. J., Mishra, A., Rutherford, R., Ramanathan, R. P., Goeminne, P. C., Vasudev, P., Dimakou, K., Crichton, M. L., Jayaraj, B. S., Kungwani, R., Das, A., Sawhney, M., Polverino, E., Torres, A., Gulecha, N. S., Shteinberg, M., De Soyza, A., Mangala, A., Shah, P., Chauhan, N. K., Jajodia, N., Singhal, A., Batra, S., Hasan, A., Limaye, S., Salvi, S., Aliberti, S. & Chalmers, J. D., 1 Sep 2019, In : The Lancet Global Health. 7, 9, p. e1269-e1279 11 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
75 Downloads (Pure)

Bronchiectasis insanity: Doing the same thing over and over again and expecting different results?

Metersky, M. & Chalmers, J., 15 Mar 2019, In : F1000Research. 8, p. 1-7 7 p., 293.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
102 Downloads (Pure)

Bronchiectasis Management: The State of the Union

Chalmers, J. D. & Restrepo, M. I., Dec 2017, In : Chest. 152, 6, p. 1097-1099 3 p.

Research output: Contribution to journalEditorial

2 Citations (Scopus)

Bronchiectasis Rheumatoid Overlap Syndrome Is an Independent Risk Factor for Mortality in Patients With Bronchiectasis: A Multicenter Cohort Study

De Soyza, A., McDonnell, M. J., Goeminne, P. C., Aliberti, S., Lonni, S., Davison, J., Dupont, L. J., Fardon, T. C., Rutherford, R. M., Hill, A. T. & Chalmers, J. D., Jun 2017, In : Chest. 151, 6, p. 1247-1254 8 p.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
178 Downloads (Pure)

Cardiovascular disease as a complication of community-acquired pneumonia

Rae, N., Finch, S. & Chalmers, J. D., May 2016, In : Current Opinion in Pulmonary Medicine. 22, 3, p. 212-218 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Challenges in severe community-acquired pneumonia: a point-of-view review

Torres, A., Chalmers, J. D., Dela Cruz, C. S., Dominedò, C., Kollef, M., Martin-Loeches, I., Niederman, M. & Wunderink, R. G., Feb 2019, In : Intensive Care Medicine. 45, 2, p. 159-171 13 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)

Changes in respiratory symptoms during 48 weeks treatment with ARD-3150 (inhaled liposomal ciprofloxacin) in bronchiectasis: results from the ORBIT-3 and -4 studies

Chalmers, J. D., Cipolla, D., Thompson, B., Davis, A. M., O'Donnell, A., Tino, G., Gonda, I., Haworth, C. & Froehlich, J., 18 Jun 2020, In : European Respiratory Journal. 55, 6

Research output: Contribution to journalArticle

Characterization of bronchiectasis in the elderly

Bellelli, G., Chalmers, J. D., Sotgiu, G., Dore, S., McDonnell, M. J., Goeminne, P. C., Dimakou, K., Skrbic, D., Lombi, A., Pane, F., Obradovic, D., Fardon, T. C., Rutherford, R. M., Pesci, A. & Aliberti, S., Oct 2016, In : Respiratory Medicine. 119, p. 13-19 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
281 Downloads (Pure)

Characterizing non-tuberculous mycobacteria infection in bronchiectasis

Faverio, P., Stainer, A., Bonaiti, G., Zucchetti, S. C., Simonetta, E., Lapadula, G., Marruchella, A., Gori, A., Blasi, F., Codecasa, L., Pesci, A., Chalmers, J. D., Loebinger, M. R. & Aliberti, S., 16 Nov 2016, In : International Journal of Molecular Sciences. 17, 11, 12 p., 1913.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
135 Downloads (Pure)

Clinical phenotypes in adult patients with bronchiectasis

Aliberti, S., Lonni, S., Dore, S., McDonnell, M. J., Goeminne, P. C., Dimakou, K., Fardon, T., Rutherford, R., Pesci, A., Restrepo, M. I., Sotgiu, G. & Chalmers, J., 1 Apr 2016, In : European Respiratory Journal. 47, 4, p. 1113-1122 10 p.

Research output: Contribution to journalArticle

Open Access
File
122 Citations (Scopus)
140 Downloads (Pure)

Clinical phenotypes in bronchiectasis: Right on track to develop precision medicine in respiratory diseases

Sotgiu, G., Dore, S., Chalmers, J. D. & Aliberti, S., 1 May 2016, In : International Journal of Tuberculosis and Lung Disease. 20, 5, p. 709 1 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Community-Acquired Pneumonia: A Global Perspective

Feldman, C. & Chalmers, J. D., Dec 2016, In : Seminars in Respiratory and Critical Care Medicine. 37, 6, p. 797-798 2 p.

Research output: Contribution to journalEditorial

Open Access
File
1 Citation (Scopus)
153 Downloads (Pure)

Community-acquired pneumonia in the United Kingdom: a call to action

Chalmers, J., Campling, J., Ellsbury, G., Hawkey, P. M., Madhava, H. & Slack, M., 5 Oct 2017, In : Pneumonia . 9, 6 p., 15.

Research output: Contribution to journalComment/debate

Open Access
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174 Downloads (Pure)

Community-acquired pneumonia related to intracellular pathogens

Cillóniz, C., Torres, A., Niederman, M., van der Eerden, M., Chalmers, J., Welte, T. & Blasi, F., Sep 2016, In : Intensive Care Medicine. 42, 9, p. 1374-1386 13 p.

Research output: Contribution to journalArticle

Open Access
File
29 Citations (Scopus)
388 Downloads (Pure)

Comorbidities and the risk of mortality in patients with bronchiectasis: an international mulitcentre cohort study

McDonnell, M. J., Aliberti, S., Goeminne, P. C., Restrepo, M. I., Finch, S., Pesci, A., Dupont, L., Fardon, T., Wilson, R., Loebinger, M., Skrbic, D., Obradovic, D., De Soyza, A., Ward, C., Laffey, J. G., Rutherford, R. & Chalmers, J., Dec 2016, In : The Lancet Respiratory Medicine. 4, 12, p. 969-979 11 p.

Research output: Contribution to journalArticle

Open Access
File
84 Citations (Scopus)
155 Downloads (Pure)

Continuous versus intermittent antibiotics for non-cystic fibrosis bronchiectasis

Donovan, T., Felix, L. M., Chalmers, J. D., Milan, S. J., Mathioudakis, A. G. & Spencer, S., 26 Jul 2017, In : Cochrane Database of Systematic Reviews. 2017, 7, p. 1-13 13 p., CD012733.

Research output: Contribution to journalArticle

Open Access
File
99 Downloads (Pure)

Control of Confounding and Reporting of Results in Causal Inference Studies: Guidance for Authors from Editors of Respiratory, Sleep, and Critical Care Journals

Lederer, D. J., Bell, S. C., Branson, R. D., Chalmers, J. D., Marshall, R., Maslove, D. M., Ost, D. E., Punjabi, N. M., Schatz, M., Smyth, A. R., Stewart, P. W., Suissa, S., Adjei, A. A., Akdis, C. A., Azoulay, É., Bakker, J., Ballas, Z. K., Bardin, P. G., Barreiro, E., Bellomo, R. & 28 others, Bernstein, J. A., Brusasco, V., Buchman, T. G., Chokroverty, S., Collop, N. A., Crapo, J. D., Fitzgerald, D. A., Hale, L., Hart, N., Herth, F. J., Iwashyna, T. J., Jenkins, G., Kolb, M., Marks, G. B., Mazzone, P., Moorman, J. R., Murphy, T. M., Noah, T. L., Reynolds, P., Riemann, D., Russell, R. E., Sheikh, A., Sotgiu, G., Swenson, E. R., Szczesniak, R., Szymusiak, R., Teboul, J-L. & Vincent, J-L., Jan 2019, In : Annals of the American Thoracic Society. 16, 1, p. 22-28 7 p.

Research output: Contribution to journalArticle

Open Access
File
104 Citations (Scopus)
342 Downloads (Pure)

Corticosteroids for community-acquired pneumonia: a critical view of the evidence

Chalmers, J. D., 1 Oct 2016, In : European Respiratory Journal. 48, 4, p. 984-986 3 p.

Research output: Contribution to journalEditorial

10 Citations (Scopus)

Counting the cost of bronchiectasis

Gao, Y-H. & Chalmers, J. D., 30 Jun 2020, In : Respirology . 2 p.

Research output: Contribution to journalEditorial

Cystic fibrosis lung disease and bronchiectasis

Chalmers, J. D., Jan 2020, In : The Lancet Respiratory Medicine. 8, 1, p. 12-14 3 p.

Research output: Contribution to journalComment/debate

Open Access
File
27 Downloads (Pure)

Determinants of initial inhaled corticosteroid use in patients with GOLD A/B COPD: a retrospective study of UK general practice

Chalmers, J. D., Tebboth, A., Gayle, A., Ternouth, A. & Ramscar, N., 29 Jun 2017, In : NPJ Primary Care Respiratory Medicine. 27, p. 1-8 8 p., 43.

Research output: Contribution to journalArticle

Open Access
File
26 Citations (Scopus)
170 Downloads (Pure)

Development and initial validation of the bronchiectasis exacerbation and symptom tool (BEST)

Artaraz, A., Crichton, M. L., Finch, S., Abo-Leyah, H., Goeminne, P., Aliberti, S., Fardon, T. & Chalmers, J. D., 13 Jan 2020, In : Respiratory Research. 21, 1, p. 1-9 1 p., 18.

Research output: Contribution to journalArticle

Open Access
File
42 Downloads (Pure)

Development and Reporting of Prediction Models: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals

Leisman, D. E., Harhay, M. O., Lederer, D. J., Abramson, M., Adjei, A. A., Bakker, J., Ballas, Z. K., Barreiro, E., Bell, S. C., Bellomo, R., Bernstein, J. A., Branson, R. D., Brusasco, V., Chalmers, J. D., Chokroverty, S., Citerio, G., Collop, N. A., Cooke, C. R., Crapo, J. D., Donaldson, G. & 19 others, Fitzgerald, D. A., Grainger, E., Hale, L., Herth, F. J., Kochanek, P. M., Marks, G., Moorman, J. R., Ost, D. E., Schatz, M., Sheikh, A., Smyth, A. R., Stewart, I., Stewart, P. W., Swenson, E. R., Szymusiak, R., Teboul, J-L., Vincent, J-L., Wedzicha, J. A. & Maslove, D. M., May 2020, In : Critical Care Medicine. 48, 5, p. 623-633 11 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
161 Downloads (Pure)

Diagnostic challenges of bronchiectasis

Suarez-Cuartin, G., Chalmers, J. D. & Sibila, O., 1 Jul 2016, In : Respiratory Medicine. 116, p. 70-77 8 p.

Research output: Contribution to journalReview article

Open Access
File
15 Citations (Scopus)
172 Downloads (Pure)

Distinct 'Immuno-Allertypes' of Disease and High Frequencies of Sensitisation in Non-Cystic-Fibrosis Bronchiectasis

Mac Aogáin, M., Tiew, P. Y., Lim, A. Y. H., Low, T. B., Tan, G. L., Hassan, T., Ong, T. H., Pang, S. L., Lee, Z. Y., Gwee, X. W., Martinus, C., Sio, Y. Y., Matta, S. A., Ong, T. C., Tiong, Y. S., Wong, K. N., Narayanan, S., Bijin Au, V., Marlier, D., Keir, H. R. & 8 others, Tee, A., Abisheganaden, J. A., Koh, M. S., Wang, D. Y., Connolly, J. E., Chew, F. T., Chalmers, J. D. & Chotirmall, S. H., 1 Apr 2019, In : American Journal of Respiratory and Critical Care Medicine. 199, 7, p. 842-853 12 p.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
183 Downloads (Pure)

Empirical coverage of methicillin-resistant Staphylococcus aureus in community-acquired pneumonia: those who do not remember the past are doomed to repeat it

Chalmers, J. D., Reyes, L. F., Aliberti, S. & Restrepo, M. I., 15 Oct 2016, In : Clinical Infectious Diseases. 63, 8, p. 1145-1146 1 p.

Research output: Contribution to journalLetter

8 Citations (Scopus)
16 Downloads (Pure)

Endothelial adhesion molecules and multiple organ failure in patients with severe sepsis

Amalakuhan, B., Habib, S. A., Mangat, M., Reyes, L. F., Rodriguez, A. H., Hinojosa, C. A., Soni, N. J., Gilley, R. P., Bustamante, C. A., Anzueto, A., Levine, S. M., Peters, J. I., Aliberti, S., Sibila, O., Chalmers, J. D., Torres, A., Waterer, G. W., Martin-Loeches, I., Bordon, J., Blanquer, J. & 15 others, Sanz, F., Marcos, P. J., Rello, J., Ramirez, J., Solé-Violán, J., Luna, C. M., Feldman, C., Witzenrath, M., Wunderink, R. G., Stolz, D., Wiemken, T. L., Shindo, Y., Dela Cruz, C. S., Orihuela, C. J. & Restrepo, M. I., Dec 2016, In : Cytokine. 88, p. 267-273 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
122 Downloads (Pure)
Open Access
File
2 Downloads (Pure)

European Respiratory Society guidelines for the management of adult bronchiectasis

Polverino, E., Goeminne, P. C., McDonnell, M. J., Aliberti, S., Marshall, S. E., Loebinger, M. R., Murris-Espin, M., Cantón, R., Torres, A., Dimakou, K., De Soyza, A., Hill, A. T., Haworth, C. S., Vendrell, M., Ringshausen, F. C., Subotic, D., Wilson, R., Vilaró, J., Stallberg, B., Welte, T. & 9 others, Rohde, G., Blasi, F., Elborn, J. S., Almagro, M., Timothy, A., Ruddy, T., Tonia, T., Rigau, D. & Chalmers, J. D., Sep 2017, In : European Respiratory Journal. 50, 3, p. 1-23 23 p., 1700629.

Research output: Contribution to journalArticle

Open Access
File
244 Citations (Scopus)
222 Downloads (Pure)

Evaluation of active neutrophil elastase in sputum of bronchiectasis and cystic fibrosis patients: A comparison among different techniques

Oriano, M., Terranova, L., Sotgiu, G., Saderi, L., Bellofiore, A., Retucci, M., Marotta, C., Gramegna, A., Miglietta, D., Carnini, C., Marchisio, P., Chalmers, J. D., Aliberti, S. & Blasi, F., Dec 2019, In : Pulmonary Pharmacology & Therapeutics. 59, p. 1-6 6 p., 101856.

Research output: Contribution to journalArticle

2 Citations (Scopus)