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  • 2020
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  • Craig Mowat
2020

Faecal haemoglobin can define risk of colorectal neoplasia at surveillance colonoscopy in patients at increased risk of colorectal cancer.

Digby, J., Cleary, S., Gray, L., Datt, P., Goudie, D. R., Steele, R. J. C., Strachan, J. A., Humphries, A., Fraser, C. G. & Mowat, C., 1 Jun 2020, In : United European Gastroenterology Journal. 8, 5, p. 559-566 8 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
15 Downloads (Pure)
2019
Open Access
File
2 Citations (Scopus)
59 Downloads (Pure)

Association of Genetic Variants in NUDT15 with Thiopurine-Induced Myelosuppression in Patients with Inflammatory Bowel Disease

Walker, G. J., Harrison, J. W., Heap, G. A., Voskuil, M. D., Andersen, V., Anderson, C. A., Ananthakrishnan, A. N., Barrett, J. C., Beaugerie, L., Bewshea, C. M., Cole, A. T., Cummings, F. R., Daly, M. J., Ellul, P., Fedorak, R. N., Festen, E. A. M., Florin, T. H., Gaya, D. R., Halfvarson, J., Hart, A. L. & 30 others, Heerasing, N. M., Hendy, P., Irving, P. M., Jones, S. E., Koskela, J., Lindsay, J. O., Mansfield, J. C., McGovern, D., Parkes, M., Pollok, R. C. G., Ramakrishnan, S., Rampton, D. S., Rivas, M. A., Russell, R. K., Schultz, M., Sebastian, S., Seksik, P., Singh, A., So, K., Sokol, H., Subramaniam, K., Todd, A., Annese, V., Weersma, R. K., Xavier, R., Ward, R., Weedon, M. N., Goodhand, J. R., Kennedy, N. A. & Ahmad, T., 26 Feb 2019, In : JAMA - Journal of the American Medical Association. 321, 8, p. 773-785 13 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

Romagnoni, A., Jégou, S., Van Steen, K., Wainrib, G. & Hugot, J-P., 17 Jul 2019, In : Scientific Reports. 9, 1, p. 1-18 18 p., 10351.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
57 Downloads (Pure)

Do other variables add value to assessment of the risk of colorectal disease using faecal immunochemical tests for haemoglobin?

Digby, J., Steele, B., Strachan, J. A., Mowat, C., Anderson, A., McCann, R., Law, L. & Fraser, C., 1 Jul 2019, In : Annals of Clinical Biochemistry. 56, 4, p. 472-479 8 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
48 Downloads (Pure)

Impact of introducing a faecal immunochemical test (FIT) for haemoglobin into primary care on the outcome of patients with new bowel symptoms: A prospective cohort study

Mowat, C., Digby, J., Strachan, J. A., McCann, R., Hall, C., Heather, D., Carey, F., Fraser, C. & Steele, B., 4 May 2019, In : BMJ Open Gastroenterology. 6, 1, p. 1-8 8 p., e000293.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
120 Downloads (Pure)

Lifestyle in patients at increased risk of colorectal cancer

Anderson, A. S., Caswell, S., Mowat, C., Strachan, J. A. & Steele, R. J. C., Oct 2019, In : Journal of Human Nutrition and Dietetics. 32, 5, p. 570-577 8 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
12 Downloads (Pure)
13 Downloads (Pure)

Randomized controlled trial: Flexible sigmoidoscopy as an adjunct to faecal occult blood testing in population screening

Steele, R. J. C., Carey, F. A., Stanners, G., Lang, J., Brand, J., Brownlee, L. A., Crichton, E. M., Winter, J. W., Phull, P. S., Mowat, C., Strachan, J. A., Digan, A-M. & Fraser, C. G., 5 Nov 2019, In : Journal of Medical Screening.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
256 Downloads (Pure)

Real-world effectiveness and safety of Vedolizumab for the treatment of Inflammatory Bowel Disease: The Scottish Vedolizumab Cohort

Plevris, N., Chuah, C. S., Allen, R. M., Arnott, I. D., Brennan, P. N., Chaudhary, S., Churchhouse, A. M. D., Din, S., Donoghue, E., Gaya, D. R., Groome, M., Jafferbhoy, H. M., Jenkinson, P. W., Lam, W. L., Lyons, M., Macdonald, J. C., MacMaster, M., Mowat, C., Naismith, G. D., Potts, L. F. & 11 others, Saffouri, E., Seenan, J. P., Sengupta, A., Shasi, P., Sutherland, D. I., Todd, J. A., Veryan, J., Watson, A. J. M., Watts, D., Jones, G. R. & Lees, C. W., Sep 2019, In : Journal of Crohn's and Colitis. 13, 9, p. 1111-1120 10 p.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
78 Downloads (Pure)
2017

A plea for TDM-based optimisation for treatment of Crohn's disease - Authors' reply

Kennedy, N. A., Keerie, C., Mowat, C. & Satsangi, J., Feb 2017, In : Lancet Gastroenterology and Hepatology. 2, 2, p. 81-82 2 p.

Research output: Contribution to journalLetter

A randomised, double-blind, parallel-group trial to assess mercaptopurine versus placebo to prevent or delay recurrence of Crohn's disease following surgical resection (TOPPIC)

Satsangi, J., Kennedy, N. A., Mowat, C., Arnott, I., Keerie, C., Lewis, S., Ennis, H. & on behalf of the TOPPIC Collaborators Group, Sep 2017, In : Efficacy and Mechanism Evaluation. 4, 4, p. 1-59 86 p.

Research output: Contribution to journalArticle

Open Access
File
184 Downloads (Pure)

Are patients in the IBD clinic at risk of proctitis secondary to sexually transmitted infections?

Groome, M., Robinson, E. M., Mowat, C., Morieux, A. M. L. & Allstaff, S., Oct 2017, In : Frontline Gastroenterology. 8, 4, p. 267-271 5 p.

Research output: Contribution to journalArticle

Can a negative fit test avoid the need for a routine surveillance colonoscopy?

Digby, J., Cleary, S., Datt, P., Grey, L., Goudie, D., Steele, B., Humphries, A., Strachan, J. & Mowat, C., Jul 2017, In : Gut. 66, Suppl. 2, p. A132-A133 2 p., PWE-015.

Research output: Contribution to journalArticle

Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7

Luo, Y., de Lange, K. M., Jostins, L., Moutsianas, L., Randall, J., Kennedy, N. A., Lamb, C. A., McCarthy, S., Ahmad, T., Edwards, C., Serra, E. G., Hart, A., Hawkey, C., Mansfield, J. C., Mowat, C., Newman, W. G., Nichols, S., Pollard, M., Satsangi, J., Simmons, A. & 10 others, Tremelling, M., Uhlig, H., Wilson, D. C., Lee, J. C., Prescott, N. J., Lees, C. W., Mathew, C. G., Parkes, M., Barrett, J. C. & Anderson, C. A., 9 Jan 2017, In : Nature Genetics. 49, 2, p. 186-192 9 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

de Lange, K. M., Moutsianas, L., Lee, J. C., Lamb, C. A., Luo, Y., Kennedy, N. A., Jostins, L., Rice, D. L., Gutierrez-Achury, J., Ji, S-G., Heap, G., Nimmo, E. R., Edwards, C., Henderson, P., Mowat, C., Sanderson, J., Satsangi, J., Simmons, A., Wilson, D. C., Tremelling, M. & 12 others, Hart, A., Mathew, C. G., Newman, W. G., Parkes, M., Lees, C. W., Uhlig, H., Hawkey, C., Prescott, N. J., Ahmad, T., Mansfield, J. C., Anderson, C. A. & Barrett, J. C., 9 Jan 2017, In : Nature Genetics. 49, 2, p. 256-261 6 p.

Research output: Contribution to journalLetter

199 Citations (Scopus)

The FAST (Faecal Haemoglobin Concentration, Age and Sex Test) Score: development and external validation of a simple prediction tool for colorectal cancer detection in symptomatic patients

on behalf of the COLONPREDICT study investigators, 15 May 2017, In : International Journal of Cancer. 140, 10, p. 2201-2211 11 p.

Research output: Contribution to journalArticle

Open Access
File
25 Citations (Scopus)
94 Downloads (Pure)
2016

A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies

Bodea, C. A., Neale, B. M., Ripke, S., International IBD Genetics Consortium, Daly, M. J., Devlin, B. & Roeder, K., 5 May 2016, In : American Journal of Human Genetics. 98, 5, p. 857-868 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Clinical features and HLA association of 5-aminosalicylate (5-ASA)-induced nephrotoxicity in inflammatory bowel disease

Heap, G. A., So, K., Weedon, M., Edney, N., Bewshea, C., Singh, A., Annese, V., Beckly, J., Buurman, D., Chaudhary, R., Cole, A. T., Cooper, S. C., Creed, T., Cummings, F., de Boer, N. K., D'Inca, R., Daneshmend, T. K., Delaney, M., Dhar, A., Direkze, N. & 43 others, Dunckley, P., Gaya, D. R., Gearry, R., Gore, S., Halfvarson, J., Hart, A. L., Hawkey, C. J., Hoentjen, F., Iqbal, T., Irving, P., Lal, S., Lawrence, I., Lees, C. W., Lewis, S., Lockett, M., Mann, S., Mansfield, J. C., Mowat, C., Muller, F., Murray, C., Orchard, T., Parkes, M., Phillips, R., Pollok, R., Radford-Smith, G. L., Sebastian, S., Sen, S., Shirazi, T., Silverberg, M. S., Solomon, L., Sturniolo, G. C., Thomas, M., Tremelling, M., Tsianos, E. V., Watts, D., Weaver, S., Wesley, E., Holden, A., D'Souza, R., Mulgrew, C. J., Oram, R. A., Weersma, R. K. & Ahmad, T., 1 Feb 2016, In : Journal of Crohn's and Colitis. 10, 2, p. 149-158 10 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Mercaptopurine versus placebo to prevent recurrence of Crohn's disease after surgical resection (TOPPIC): a multicentre, double-blind, randomised controlled trial

Mowat, C., Arnott, I., Cahill, A., Smith, M., Ahmad, T., Subramanian, S., Travis, S., Morris, J., Hamlin, J., Dhar, A., Nwokolo, C., Edwards, C., Creed, T., Bloom, S., Yousif, M., Thomas, L., Campbell, S., Lewis, S. J., Sebastian, S., Sen, S. & 23 others, Lal, S., Hawkey, C., Murray, C., Cummings, F., Goh, J., Lindsay, J. O., Arebi, N., Potts, L., McKinley, A. J., Thomson, J. M., Todd, J. A., Collie, M., Dunlop, M. G., Mowat, A., Gaya, D. R., Winter, J., Naismith, G. D., Ennis, H., Keerie, C., Lewis, S., Prescott, R. J., Kennedy, N. A. & Satsangi, J., Dec 2016, In : Lancet Gastroenterology and Hepatology. 1, 4, p. 273-282 10 p.

Research output: Contribution to journalArticle

Open Access
File
40 Citations (Scopus)
160 Downloads (Pure)