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  • 2020
  • 2017
  • 2016

Author

  • James Chalmers
Article

Airway Mucin 2 is decreased in patients with severe chronic obstructive pulmonary disease with bacterial colonization

Sibila, O., Garcia-Bellmunt, L., Giner, J., Rodrigo-Troyano, A., Suarez-Cuartin, G., Torrego, A., Castillo, D., Solanes, I., Mateus, E. F., Vidal, S., Sanchez-Reus, F., Sala, E., Cosio, B. G., Restrepo, M. I., Anzueto, A., Chalmers, J. D. & Plaza, V., 1 May 2016, In : Annals of the American Thoracic Society. 13, 5, p. 636-642 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Anti-Pseudomonas aeruginosa IgG antibodies and chronic airway infection in bronchiectasis

Suarez-Cuartin, G., Smith, A., Abo-Leyah, H., Rodrigo-Troyano, A., Perea, L., Vidal, S., Plaza, V., Fardon, T. C., Sibila, O. & Chalmers, J. D., Jul 2017, In : Respiratory Medicine. 128, p. 1-6 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

A randomised control trial of atorvastatin in bronchiectasis patients infected with Pseudomonas aeruginosa- a proof of concept study

Bedi, P., Chalmers, J. D., Graham, C., Clarke, A., Donaldson, S., Doherty, C. J., Govan, J. R. W., Davidson, D. J., Rossi, A. G. & Hill, A. T., Aug 2017, In : Chest. 152, 2, p. 368-378 11 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
143 Downloads (Pure)

A systematic review of the burden of vaccine preventable pneumococcal disease in UK adults

Chalmers, J. D., Dicker, A., Woodhead, M. & Madhava, H., 11 May 2016, In : BMC Pulmonary Medicine. 16, 1, p. 1-11 11 p., 77.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
196 Downloads (Pure)

Blood neutrophil counts are associated with exacerbation frequency and mortality in COPD

Lonergan, M., Dicker, A. J., Crichton, M. L., Keir, H. R., Van Dyke, M. K., Mullerova, H., Miller, B. E., Tal-Singer, R. & Chalmers, J. D., 1 Jul 2020, In : Respiratory Research. 21, p. 1-10 10 p., 166.

Research output: Contribution to journalArticle

Open Access
File
3 Downloads (Pure)

Bronchiectasis: Phenotyping a Complex Disease

Chalmers, J. D., 17 Mar 2017, In : COPD. 14, Suppl.1, p. S12-S18 7 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
150 Downloads (Pure)

Bronchiectasis Rheumatoid Overlap Syndrome Is an Independent Risk Factor for Mortality in Patients With Bronchiectasis: A Multicenter Cohort Study

De Soyza, A., McDonnell, M. J., Goeminne, P. C., Aliberti, S., Lonni, S., Davison, J., Dupont, L. J., Fardon, T. C., Rutherford, R. M., Hill, A. T. & Chalmers, J. D., Jun 2017, In : Chest. 151, 6, p. 1247-1254 8 p.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
174 Downloads (Pure)

Cardiovascular disease as a complication of community-acquired pneumonia

Rae, N., Finch, S. & Chalmers, J. D., May 2016, In : Current Opinion in Pulmonary Medicine. 22, 3, p. 212-218 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Changes in respiratory symptoms during 48 weeks treatment with ARD-3150 (inhaled liposomal ciprofloxacin) in bronchiectasis: results from the ORBIT-3 and -4 studies

Chalmers, J. D., Cipolla, D., Thompson, B., Davis, A. M., O'Donnell, A., Tino, G., Gonda, I., Haworth, C. & Froehlich, J., 18 Jun 2020, In : European Respiratory Journal. 55, 6

Research output: Contribution to journalArticle

Characterization of bronchiectasis in the elderly

Bellelli, G., Chalmers, J. D., Sotgiu, G., Dore, S., McDonnell, M. J., Goeminne, P. C., Dimakou, K., Skrbic, D., Lombi, A., Pane, F., Obradovic, D., Fardon, T. C., Rutherford, R. M., Pesci, A. & Aliberti, S., Oct 2016, In : Respiratory Medicine. 119, p. 13-19 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
275 Downloads (Pure)

Characterizing non-tuberculous mycobacteria infection in bronchiectasis

Faverio, P., Stainer, A., Bonaiti, G., Zucchetti, S. C., Simonetta, E., Lapadula, G., Marruchella, A., Gori, A., Blasi, F., Codecasa, L., Pesci, A., Chalmers, J. D., Loebinger, M. R. & Aliberti, S., 16 Nov 2016, In : International Journal of Molecular Sciences. 17, 11, 12 p., 1913.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
132 Downloads (Pure)

Clinical phenotypes in adult patients with bronchiectasis

Aliberti, S., Lonni, S., Dore, S., McDonnell, M. J., Goeminne, P. C., Dimakou, K., Fardon, T., Rutherford, R., Pesci, A., Restrepo, M. I., Sotgiu, G. & Chalmers, J., 1 Apr 2016, In : European Respiratory Journal. 47, 4, p. 1113-1122 10 p.

Research output: Contribution to journalArticle

Open Access
File
122 Citations (Scopus)
136 Downloads (Pure)

Community-acquired pneumonia related to intracellular pathogens

Cillóniz, C., Torres, A., Niederman, M., van der Eerden, M., Chalmers, J., Welte, T. & Blasi, F., Sep 2016, In : Intensive Care Medicine. 42, 9, p. 1374-1386 13 p.

Research output: Contribution to journalArticle

Open Access
File
29 Citations (Scopus)
379 Downloads (Pure)

Comorbidities and the risk of mortality in patients with bronchiectasis: an international mulitcentre cohort study

McDonnell, M. J., Aliberti, S., Goeminne, P. C., Restrepo, M. I., Finch, S., Pesci, A., Dupont, L., Fardon, T., Wilson, R., Loebinger, M., Skrbic, D., Obradovic, D., De Soyza, A., Ward, C., Laffey, J. G., Rutherford, R. & Chalmers, J., Dec 2016, In : The Lancet Respiratory Medicine. 4, 12, p. 969-979 11 p.

Research output: Contribution to journalArticle

Open Access
File
84 Citations (Scopus)
153 Downloads (Pure)

Continuous versus intermittent antibiotics for non-cystic fibrosis bronchiectasis

Donovan, T., Felix, L. M., Chalmers, J. D., Milan, S. J., Mathioudakis, A. G. & Spencer, S., 26 Jul 2017, In : Cochrane Database of Systematic Reviews. 2017, 7, p. 1-13 13 p., CD012733.

Research output: Contribution to journalArticle

Open Access
File
98 Downloads (Pure)

Determinants of initial inhaled corticosteroid use in patients with GOLD A/B COPD: a retrospective study of UK general practice

Chalmers, J. D., Tebboth, A., Gayle, A., Ternouth, A. & Ramscar, N., 29 Jun 2017, In : NPJ Primary Care Respiratory Medicine. 27, p. 1-8 8 p., 43.

Research output: Contribution to journalArticle

Open Access
File
26 Citations (Scopus)
166 Downloads (Pure)

Development and initial validation of the bronchiectasis exacerbation and symptom tool (BEST)

Artaraz, A., Crichton, M. L., Finch, S., Abo-Leyah, H., Goeminne, P., Aliberti, S., Fardon, T. & Chalmers, J. D., 13 Jan 2020, In : Respiratory Research. 21, 1, p. 1-9 1 p., 18.

Research output: Contribution to journalArticle

Open Access
File
38 Downloads (Pure)

Development and Reporting of Prediction Models: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals

Leisman, D. E., Harhay, M. O., Lederer, D. J., Abramson, M., Adjei, A. A., Bakker, J., Ballas, Z. K., Barreiro, E., Bell, S. C., Bellomo, R., Bernstein, J. A., Branson, R. D., Brusasco, V., Chalmers, J. D., Chokroverty, S., Citerio, G., Collop, N. A., Cooke, C. R., Crapo, J. D., Donaldson, G. & 19 others, Fitzgerald, D. A., Grainger, E., Hale, L., Herth, F. J., Kochanek, P. M., Marks, G., Moorman, J. R., Ost, D. E., Schatz, M., Sheikh, A., Smyth, A. R., Stewart, I., Stewart, P. W., Swenson, E. R., Szymusiak, R., Teboul, J-L., Vincent, J-L., Wedzicha, J. A. & Maslove, D. M., May 2020, In : Critical Care Medicine. 48, 5, p. 623-633 11 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
153 Downloads (Pure)

Endothelial adhesion molecules and multiple organ failure in patients with severe sepsis

Amalakuhan, B., Habib, S. A., Mangat, M., Reyes, L. F., Rodriguez, A. H., Hinojosa, C. A., Soni, N. J., Gilley, R. P., Bustamante, C. A., Anzueto, A., Levine, S. M., Peters, J. I., Aliberti, S., Sibila, O., Chalmers, J. D., Torres, A., Waterer, G. W., Martin-Loeches, I., Bordon, J., Blanquer, J. & 15 others, Sanz, F., Marcos, P. J., Rello, J., Ramirez, J., Solé-Violán, J., Luna, C. M., Feldman, C., Witzenrath, M., Wunderink, R. G., Stolz, D., Wiemken, T. L., Shindo, Y., Dela Cruz, C. S., Orihuela, C. J. & Restrepo, M. I., Dec 2016, In : Cytokine. 88, p. 267-273 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
122 Downloads (Pure)
Open Access

European Respiratory Society guidelines for the management of adult bronchiectasis

Polverino, E., Goeminne, P. C., McDonnell, M. J., Aliberti, S., Marshall, S. E., Loebinger, M. R., Murris-Espin, M., Cantón, R., Torres, A., Dimakou, K., De Soyza, A., Hill, A. T., Haworth, C. S., Vendrell, M., Ringshausen, F. C., Subotic, D., Wilson, R., Vilaró, J., Stallberg, B., Welte, T. & 9 others, Rohde, G., Blasi, F., Elborn, J. S., Almagro, M., Timothy, A., Ruddy, T., Tonia, T., Rigau, D. & Chalmers, J. D., Sep 2017, In : European Respiratory Journal. 50, 3, p. 1-23 23 p., 1700629.

Research output: Contribution to journalArticle

Open Access
File
240 Citations (Scopus)
205 Downloads (Pure)

Evaluation of serum inflammatory biomarkers as predictors of treatment outcome in pulmonary tuberculosis

Singanayagam, A., Manalan, K., Connell, D. W., Chalmers, J. D., Sridhar, S., Ritchie, A. I., Lalvani, A., Wickremasinghe, M. & Kon, O. M., 1 Dec 2016, In : International Journal of Tuberculosis and Lung Disease. 20, 12, p. 1653-1660 8 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
143 Downloads (Pure)

Evaluation of severity score-guided approaches to macrolide use in community-acquired pneumonia

Singanayagam, A., Aliberti, S., Cillóniz, C., Torres, A., Blasi, F. & Chalmers, J. D., Sep 2017, In : European Respiratory Journal. 50, 3, 1602306.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
176 Downloads (Pure)

Increased Chitotriosidase is Associated with Aspergillus and Frequent Exacerbations in South-East Asians with Bronchiectasis

Poh, T. Y., Tiew, P. Y., Hou Lim, A. Y., Thng, K. X., Binte Mohamed Ali, N. A., Narayana, J. K., Aogáin, M. M., Tien, Z., Chew, W. M., Wai Chan, A. K., Keir, H. R., Dicker, A. J., Hassan, T. M., Xu, H., Tee, A. K. H., Ong, T. H., Koh, M. S., Abisheganaden, J. A., Chalmers, J. D. & Chotirmall, S. H., 14 Mar 2020, In : Chest.

Research output: Contribution to journalArticle

Is bronchiectasis really a disease?

Shteinberg, M., Flume, P. A. & Chalmers, J. D., 31 Mar 2020, In : European Respiratory Review. 29, 155, p. 1-10 10 p., 190051.

Research output: Contribution to journalArticle

Open Access
File
40 Downloads (Pure)

Management of chronic airway diseases: What can we learn from real-life data?

Chalmers, J. D., 17 Mar 2017, In : COPD. 14, Suppl. 1, p. S1-S2 2 p.

Research output: Contribution to journalArticle

Open Access
File
191 Downloads (Pure)

Managing and preventing exacerbation of bronchiectasis

Abo-Leyah, H. & Chalmers, J. D., Apr 2020, In : Current Opinion in Infectious Diseases. 33, 2, p. 189-196 8 p.

Research output: Contribution to journalArticle

Multidimensional severity assessment in bronchiectasis: An analysis of 7 European cohorts.

McDonnell, M. J., Alberti, S., Goeminne, P. C., Dimakou, K., Davidson, J., Ward, C., LAffey, JG., Finch, S., Pesci, A., Dupont, LJ., Fardon, T. C., Skrbic, D., Obradovic, D., Cowman, S., Loebinger, M. R., Rutherford, RM., De Soyza, A. & Chalmers, J. D., Dec 2016, In : Thorax. 71, 12, p. 1110-1118 9 p.

Research output: Contribution to journalArticle

Open Access
File
70 Citations (Scopus)
149 Downloads (Pure)

Neutrophil elastase activity is associated with exacerbations and lung function decline in Bronchiectasis

Chalmers, J. D., Moffitt, K. L., Suarez-Cuartin, G., Sibila, O., Finch, S., Furrie, E., Dicker, A., Wrobel, K., Elborn, J. S., Walker, B., Martin, S. L., Marshall, S. E., Huang, J. T-J. & Fardon, T. C., 15 May 2017, In : American Journal of Respiratory and Critical Care Medicine. 195, 10, p. 1384-1393 10 p.

Research output: Contribution to journalArticle

Open Access
File
81 Citations (Scopus)
143 Downloads (Pure)

Oral versus intravenous clarithromycin in moderate to severe community-acquired pneumonia: an observational study

Rae, N., Singanayagam, A., Schembri, S. & Chalmers, J. D., 5 Feb 2017, In : Pneumonia . 9, p. 1-5 5 p., 2.

Research output: Contribution to journalArticle

Open Access
File
159 Downloads (Pure)
4 Citations (Scopus)

Pseudomonas aeruginosa resistance patterns and clinical outcomes in hospitalized exacerbations of COPD

Rodrigo-Troyano, A., Suarez-Cuartin, G., Peiró, M., Barril, S., Castillo, D., Sanchez-Reus, F., Plaza, V., Restrepo, M. I., Chalmers, J. D. & Sibila, O., Oct 2016, In : Respirology . 21, 7, p. 1235-1242 8 p.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
161 Downloads (Pure)

Pulmonary exacerbation in adults with bronchiectasis: a consensus definition for clinical research

Hill, A. T., Haworth, C. S., Aliberti, S., Barker, A., Blasi, F., Boersma, W., Chalmers, J. D., De Soyza, A., Dimakou, K., Elborn, J. S., Feldman, C., Flume, P., Goeminne, P. C., Loebinger, M. R., Menendez, R., Morgan, L., Murris-Espin, M., Polverino, E., Quittner, A., Ringshausen, F. C. & 9 others, Tino, G., Torres, A., Vendrell, M., Welte, T., Wilson, R., Wong, C., O'Donnell, A., Aksamit, T. & for the EMBARC/BRR definitions working group, 1 Jun 2017, In : European Respiratory Journal. 49, 6, 8 p., 1700051.

Research output: Contribution to journalArticle

Open Access
82 Citations (Scopus)

Quality standards for the management of bronchiectasis in Italy: a national audit

SIP Bronchiectasis Audit Working Group, Aliberti, S., Hill, A. T., Mantero, M., Battaglia, S., Centanni, S., Lo Cicero, S., Lacedonia, D., Saetta, M., Chalmers, J. D. & Blasi, F., 30 Jun 2016, In : European Respiratory Journal. 48, 1, p. 244-248 5 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Relationship between Symptoms, Exacerbations, and Treatment Response in Bronchiectasis

Gao, Y-H., Abo Leyah, H., Finch, S., Lonergan, M., Aliberti, S., De Soyza, A., Fardon, T. C., Tino, G. & Chalmers, J. D., 15 Jun 2020, In : American Journal of Respiratory and Critical Care Medicine. 201, 12, p. 1499-1507 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Research priorities in bronchiectasis: a consensus statement from the EMBARC Clinical Research Collaboration

Aliberti, S., Masefield, S., Polverino, E., De Soyza, A., Loebinger, M. R., Menendez, R., Ringshausen, F. C., Vendrell, M., Powell, P., Chalmers, J. D. &  on behalf of the EMBARC Study Group, 1 Sep 2016, In : European Respiratory Journal. 48, 3, p. 632-647 16 p.

Research output: Contribution to journalArticle

Open Access
File
84 Citations (Scopus)
213 Downloads (Pure)

Review of the British Thoracic Society Winter Meeting 2015, 2-4 December, London, UK

José, R. J., Chalmers, J. D., Greening, N. J. & Janes, S. M., Jun 2016, In : Thorax. 71, 6, p. 555-559 5 p.

Research output: Contribution to journalArticle

Open Access
File
208 Downloads (Pure)

Risk factors for Clostridium difficile infection in hospitalized patients with community-acquired pneumonia

Chalmers, J. D., Akram, A. R., Singanayagam, A., Wilcox, M. H. & Hill, A. T., Jul 2016, In : Journal of Infection. 73, 1, p. 45-53 9 p.

Research output: Contribution to journalArticle

Open Access
File
28 Citations (Scopus)
229 Downloads (Pure)

Role of cephalosporins in the era of Clostridium difficile infection

Wilcox, M. H., Chalmers, J. D., Nord, C. E., Freeman, J. & Bouza, E., Jan 2017, In : Journal of Antimicrobial Chemotherapy. 72, 1, p. 1-18 18 p.

Research output: Contribution to journalArticle

Open Access
File
23 Citations (Scopus)
130 Downloads (Pure)

Severe Pneumococcal Pneumonia Causes Acute Cardiac Toxicity and Subsequent Cardiac Remodeling

Reyes, L. F., Restrepo, M. I., Hinojosa, C. A., Soni, N. J., Anzueto, A., Babu, B. L., Gonzalez-Juarbe, N., Rodriguez, A. H., Jimenez, A., Chalmers, J. D., Aliberti, S., Sibila, O., Winter, V. T., Coalson, J. J., Giavedoni, L. D., Dela Cruz, C. S., Waterer, G. W., Witzenrath, M., Suttorp, N., Dube, P. H. & 1 others, Orihuela, C. J., 1 Sep 2017, In : American Journal of Respiratory and Critical Care Medicine. 196, 5, p. 609-620 12 p.

Research output: Contribution to journalArticle

Open Access
File
37 Citations (Scopus)
295 Downloads (Pure)

Sputum Neutrophil Elastase associates with microbiota and P. aeruginosa in bronchiectasis

Oriano, M., Gramegna, A., Terranova, L., Sotgiu, G., Sulaiman, I., Ruggiero, L., Saderi, L., Wu, B., Chalmers, J. D., Segal, L. N., Marchisio, P., Blasi, F. & Aliberti, S., 4 Jun 2020, In : European Respiratory Journal.

Research output: Contribution to journalArticle

Sputum neutrophil elastase in bronchiectasis: a Southern European cohort study

Gramegna, A., Aliberti, S., Sibila, O., Di Francesco, C., Sotgiu, G., Perea, L., Terranova, L., Oriano, M., Pilocane, T., Saderi, L., Chalmers, J. D., Marchisio, P. & Blasi, F., 25 Jun 2020, In : European Respiratory Journal.

Research output: Contribution to journalArticle

The EMBARC European Bronchiectasis Registry: protocol for an international observational study

Chalmers, J. D., Aliberti, S., Polverino, E., Vendrell, M., Crichton, M., Loebinger, M., Dimakou, K., Clifton, I., van der Eerden, M., Rohde, G., Murris-Espin, M., Masefield, S., Gerada, E., Shteinberg, M., Ringshausen, F., Haworth, C., Boersma, W., Rademacher, J., Hill, A. T., Aksamit, T. & 17 others, O'Donnell, A., Morgan, L., Milenkovic, B., Tramma, L., Neves, J., Menendez, R., Paggiaro, P., Botnaru, V., Skrgat, S., Wilson, R., Goeminne, P., De Soyza, A., Welte, T., Torres, A., Elborn, J. S., Blasi, F. & on behalf of EMBARC, Jan 2016, In : ERJ Open Research. 2, 1, p. 1-9 9 p., 00081-2015.

Research output: Contribution to journalArticle

Open Access
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80 Citations (Scopus)
161 Downloads (Pure)

The generalizability of bronchiectasis randomized controlled trials: a multicentre cohort study

Chalmers, J. D., McDonnell, M. J., Rutherford, R., Davidson, J., Finch, S., Crichton, M., Dupont, L., Hill, A. T., Fardon, T. C., De Soyza, A., Aliberti, S. & Goeminne, P., Mar 2016, In : Respiratory Medicine. 112, p. 51-58 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

The heterogeneity of systemic inflammation in bronchiectasis

Saleh, A. D., Chalmers, J. D., De Soyza, A., Fardon, T. C., Koustas, S. O., Scott, J., Simpson, A. J., Brown, J. S. & Hurst, J. R., Jun 2017, In : Respiratory Medicine. 127, p. 33-39 7 p.

Research output: Contribution to journalArticle

Open Access
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16 Citations (Scopus)
188 Downloads (Pure)

The Sputum Microbiome, Airway Inflammation and Mortality in Chronic Obstructive Pulmonary Disease

Dicker, A. J., Huang, J. T. J., Lonergan, M., Keir, H. R., Fong, C. J., Tan, B., Cassidy, A. J., Finch, S., Mullerova, H., Miller, B. E., Tal-Singer, R. & Chalmers, J. D., 28 Apr 2020, In : Journal of Allergy and Clinical Immunology. 10 p.

Research output: Contribution to journalArticle

The type VII secretion system of Staphylococcus aureus secretes a nuclease toxin that targets competitor bacteria

Cao, Z., Kneuper, H., Casabona, M. G., Chalmers, J. D. & Palmer, T., 10 Oct 2016, In : Nature Microbiology. 2, p. 1-11 11 p., 16183.

Research output: Contribution to journalArticle

Open Access
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69 Citations (Scopus)
289 Downloads (Pure)