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  • James Chalmers
2016

Airway Mucin 2 is decreased in patients with severe chronic obstructive pulmonary disease with bacterial colonization

Sibila, O., Garcia-Bellmunt, L., Giner, J., Rodrigo-Troyano, A., Suarez-Cuartin, G., Torrego, A., Castillo, D., Solanes, I., Mateus, E. F., Vidal, S., Sanchez-Reus, F., Sala, E., Cosio, B. G., Restrepo, M. I., Anzueto, A., Chalmers, J. D. & Plaza, V., 1 May 2016, In : Annals of the American Thoracic Society. 13, 5, p. 636-642 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

A systematic review of the burden of vaccine preventable pneumococcal disease in UK adults

Chalmers, J. D., Dicker, A., Woodhead, M. & Madhava, H., 11 May 2016, In : BMC Pulmonary Medicine. 16, 1, p. 1-11 11 p., 77.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
189 Downloads (Pure)

Cardiovascular disease as a complication of community-acquired pneumonia

Rae, N., Finch, S. & Chalmers, J. D., May 2016, In : Current Opinion in Pulmonary Medicine. 22, 3, p. 212-218 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Characterization of bronchiectasis in the elderly

Bellelli, G., Chalmers, J. D., Sotgiu, G., Dore, S., McDonnell, M. J., Goeminne, P. C., Dimakou, K., Skrbic, D., Lombi, A., Pane, F., Obradovic, D., Fardon, T. C., Rutherford, R. M., Pesci, A. & Aliberti, S., Oct 2016, In : Respiratory Medicine. 119, p. 13-19 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
262 Downloads (Pure)

Characterizing non-tuberculous mycobacteria infection in bronchiectasis

Faverio, P., Stainer, A., Bonaiti, G., Zucchetti, S. C., Simonetta, E., Lapadula, G., Marruchella, A., Gori, A., Blasi, F., Codecasa, L., Pesci, A., Chalmers, J. D., Loebinger, M. R. & Aliberti, S., 16 Nov 2016, In : International Journal of Molecular Sciences. 17, 11, 12 p., 1913.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
127 Downloads (Pure)

Clinical phenotypes in adult patients with bronchiectasis

Aliberti, S., Lonni, S., Dore, S., McDonnell, M. J., Goeminne, P. C., Dimakou, K., Fardon, T., Rutherford, R., Pesci, A., Restrepo, M. I., Sotgiu, G. & Chalmers, J., 1 Apr 2016, In : European Respiratory Journal. 47, 4, p. 1113-1122 10 p.

Research output: Contribution to journalArticle

Open Access
File
122 Citations (Scopus)
133 Downloads (Pure)

Clinical phenotypes in bronchiectasis: Right on track to develop precision medicine in respiratory diseases

Sotgiu, G., Dore, S., Chalmers, J. D. & Aliberti, S., 1 May 2016, In : International Journal of Tuberculosis and Lung Disease. 20, 5, p. 709 1 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Community-Acquired Pneumonia: A Global Perspective

Feldman, C. & Chalmers, J. D., Dec 2016, In : Seminars in Respiratory and Critical Care Medicine. 37, 6, p. 797-798 2 p.

Research output: Contribution to journalEditorial

Open Access
File
1 Citation (Scopus)
143 Downloads (Pure)

Community-acquired pneumonia related to intracellular pathogens

Cillóniz, C., Torres, A., Niederman, M., van der Eerden, M., Chalmers, J., Welte, T. & Blasi, F., Sep 2016, In : Intensive Care Medicine. 42, 9, p. 1374-1386 13 p.

Research output: Contribution to journalArticle

Open Access
File
28 Citations (Scopus)
359 Downloads (Pure)

Comorbidities and the risk of mortality in patients with bronchiectasis: an international mulitcentre cohort study

McDonnell, M. J., Aliberti, S., Goeminne, P. C., Restrepo, M. I., Finch, S., Pesci, A., Dupont, L., Fardon, T., Wilson, R., Loebinger, M., Skrbic, D., Obradovic, D., De Soyza, A., Ward, C., Laffey, J. G., Rutherford, R. & Chalmers, J., Dec 2016, In : The Lancet Respiratory Medicine. 4, 12, p. 969-979 11 p.

Research output: Contribution to journalArticle

Open Access
File
81 Citations (Scopus)
147 Downloads (Pure)

Corticosteroids for community-acquired pneumonia: a critical view of the evidence

Chalmers, J. D., 1 Oct 2016, In : European Respiratory Journal. 48, 4, p. 984-986 3 p.

Research output: Contribution to journalEditorial

10 Citations (Scopus)

Diagnostic challenges of bronchiectasis

Suarez-Cuartin, G., Chalmers, J. D. & Sibila, O., 1 Jul 2016, In : Respiratory Medicine. 116, p. 70-77 8 p.

Research output: Contribution to journalReview article

Open Access
File
15 Citations (Scopus)
163 Downloads (Pure)

Empirical coverage of methicillin-resistant Staphylococcus aureus in community-acquired pneumonia: those who do not remember the past are doomed to repeat it

Chalmers, J. D., Reyes, L. F., Aliberti, S. & Restrepo, M. I., 15 Oct 2016, In : Clinical Infectious Diseases. 63, 8, p. 1145-1146 1 p.

Research output: Contribution to journalLetter

8 Citations (Scopus)
16 Downloads (Pure)

Endothelial adhesion molecules and multiple organ failure in patients with severe sepsis

Amalakuhan, B., Habib, S. A., Mangat, M., Reyes, L. F., Rodriguez, A. H., Hinojosa, C. A., Soni, N. J., Gilley, R. P., Bustamante, C. A., Anzueto, A., Levine, S. M., Peters, J. I., Aliberti, S., Sibila, O., Chalmers, J. D., Torres, A., Waterer, G. W., Martin-Loeches, I., Bordon, J., Blanquer, J. & 15 others, Sanz, F., Marcos, P. J., Rello, J., Ramirez, J., Solé-Violán, J., Luna, C. M., Feldman, C., Witzenrath, M., Wunderink, R. G., Stolz, D., Wiemken, T. L., Shindo, Y., Dela Cruz, C. S., Orihuela, C. J. & Restrepo, M. I., Dec 2016, In : Cytokine. 88, p. 267-273 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
113 Downloads (Pure)

Evaluation of serum inflammatory biomarkers as predictors of treatment outcome in pulmonary tuberculosis

Singanayagam, A., Manalan, K., Connell, D. W., Chalmers, J. D., Sridhar, S., Ritchie, A. I., Lalvani, A., Wickremasinghe, M. & Kon, O. M., 1 Dec 2016, In : International Journal of Tuberculosis and Lung Disease. 20, 12, p. 1653-1660 8 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
137 Downloads (Pure)

Global impact of bronchiectasis and cystic fibrosis

Redondo, M., Keyt, H., Dhar, R. & Chalmers, J. D., 1 Sep 2016, In : Breathe. 12, 3, p. 222-235 14 p.

Research output: Contribution to journalReview article

Open Access
File
17 Citations (Scopus)
164 Downloads (Pure)

Macrolide antibiotics for non-cystic fibrosis bronchiectasis

Kelly, C., Evans, D. J., Chalmers, J. D., Crossingham, I., Spencer, S., Relph, N., Felix, L. M. & Milan, S. J., 21 Oct 2016, In : Cochrane Database of Systematic Reviews. 10, p. 1-11 13 p., CD012406.

Research output: Contribution to journalReview article

Open Access
File
6 Citations (Scopus)
140 Downloads (Pure)

Microbial dysbiosis after lung transplantation

Chalmers, J. D., 15 Nov 2016, In : American Journal of Respiratory and Critical Care Medicine. 194, 10, p. 1184-1186 3 p.

Research output: Contribution to journalEditorial

3 Citations (Scopus)

Multidimensional severity assessment in bronchiectasis: An analysis of 7 European cohorts.

McDonnell, M. J., Alberti, S., Goeminne, P. C., Dimakou, K., Davidson, J., Ward, C., LAffey, JG., Finch, S., Pesci, A., Dupont, LJ., Fardon, T. C., Skrbic, D., Obradovic, D., Cowman, S., Loebinger, M. R., Rutherford, RM., De Soyza, A. & Chalmers, J. D., Dec 2016, In : Thorax. 71, 12, p. 1110-1118 9 p.

Research output: Contribution to journalArticle

Open Access
File
69 Citations (Scopus)
143 Downloads (Pure)

Pseudomonas aeruginosa resistance patterns and clinical outcomes in hospitalized exacerbations of COPD

Rodrigo-Troyano, A., Suarez-Cuartin, G., Peiró, M., Barril, S., Castillo, D., Sanchez-Reus, F., Plaza, V., Restrepo, M. I., Chalmers, J. D. & Sibila, O., Oct 2016, In : Respirology . 21, 7, p. 1235-1242 8 p.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
154 Downloads (Pure)

Quality standards for the management of bronchiectasis in Italy: a national audit

SIP Bronchiectasis Audit Working Group, Aliberti, S., Hill, A. T., Mantero, M., Battaglia, S., Centanni, S., Lo Cicero, S., Lacedonia, D., Saetta, M., Chalmers, J. D. & Blasi, F., 30 Jun 2016, In : European Respiratory Journal. 48, 1, p. 244-248 5 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Reply: Measuring airway Mucin 2 in patients with severe Chronic Obstructive Pulmonary Disease with bacterial colonization

Sibila, O., Mateus, E. F., Restrepo, M. I., Chalmers, J. D. & Vidal, S., 1 Nov 2016, In : Annals of the American Thoracic Society. 13, 11, p. 2104-2105 2 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Research priorities in bronchiectasis: a consensus statement from the EMBARC Clinical Research Collaboration

Aliberti, S., Masefield, S., Polverino, E., De Soyza, A., Loebinger, M. R., Menendez, R., Ringshausen, F. C., Vendrell, M., Powell, P., Chalmers, J. D. &  on behalf of the EMBARC Study Group, 1 Sep 2016, In : European Respiratory Journal. 48, 3, p. 632-647 16 p.

Research output: Contribution to journalArticle

Open Access
File
83 Citations (Scopus)
204 Downloads (Pure)

Review of the British Thoracic Society Winter Meeting 2015, 2-4 December, London, UK

José, R. J., Chalmers, J. D., Greening, N. J. & Janes, S. M., Jun 2016, In : Thorax. 71, 6, p. 555-559 5 p.

Research output: Contribution to journalArticle

Open Access
File
204 Downloads (Pure)

Risk factors for Clostridium difficile infection in hospitalized patients with community-acquired pneumonia

Chalmers, J. D., Akram, A. R., Singanayagam, A., Wilcox, M. H. & Hill, A. T., Jul 2016, In : Journal of Infection. 73, 1, p. 45-53 9 p.

Research output: Contribution to journalArticle

Open Access
File
27 Citations (Scopus)
224 Downloads (Pure)

The EMBARC European Bronchiectasis Registry: protocol for an international observational study

Chalmers, J. D., Aliberti, S., Polverino, E., Vendrell, M., Crichton, M., Loebinger, M., Dimakou, K., Clifton, I., van der Eerden, M., Rohde, G., Murris-Espin, M., Masefield, S., Gerada, E., Shteinberg, M., Ringshausen, F., Haworth, C., Boersma, W., Rademacher, J., Hill, A. T., Aksamit, T. & 17 others, O'Donnell, A., Morgan, L., Milenkovic, B., Tramma, L., Neves, J., Menendez, R., Paggiaro, P., Botnaru, V., Skrgat, S., Wilson, R., Goeminne, P., De Soyza, A., Welte, T., Torres, A., Elborn, J. S., Blasi, F. & on behalf of EMBARC, Jan 2016, In : ERJ Open Research. 2, 1, p. 1-9 9 p., 00081-2015.

Research output: Contribution to journalArticle

Open Access
File
78 Citations (Scopus)
155 Downloads (Pure)

The generalizability of bronchiectasis randomized controlled trials: a multicentre cohort study

Chalmers, J. D., McDonnell, M. J., Rutherford, R., Davidson, J., Finch, S., Crichton, M., Dupont, L., Hill, A. T., Fardon, T. C., De Soyza, A., Aliberti, S. & Goeminne, P., Mar 2016, In : Respiratory Medicine. 112, p. 51-58 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

The Modern Diagnostic Approach to Community-Acquired Pneumonia in Adults

Chalmers, J. D., Dec 2016, In : Seminars in Respiratory and Critical Care Medicine. 37, 6, p. 876-885 10 p.

Research output: Contribution to journalReview article

Open Access
File
3 Citations (Scopus)
203 Downloads (Pure)

The type VII secretion system of Staphylococcus aureus secretes a nuclease toxin that targets competitor bacteria

Cao, Z., Kneuper, H., Casabona, M. G., Chalmers, J. D. & Palmer, T., 10 Oct 2016, In : Nature Microbiology. 2, p. 1-11 11 p., 16183.

Research output: Contribution to journalArticle

Open Access
File
68 Citations (Scopus)
280 Downloads (Pure)
2018

A comprehensive approach to lung function in bronchiectasis

Radovanovic, D., Santus, P., Blasi, F., Sotgiu, G., D'Arcangelo, F., Simonetta, E., Contarini, M., Franceschi, E., Goeminne, P. C., Chalmers, J. D. & Aliberti, S., Dec 2018, In : Respiratory Medicine. 145, p. 120-129 10 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
104 Downloads (Pure)

Advances in bronchiectasis: endotyping, genetics, microbiome, and disease heterogeneity

Flume, P. A., Chalmers, J. D. & Olivier, K. N., 8 Sep 2018, In : The Lancet. 392, 10150, p. 880-890 11 p.

Research output: Contribution to journalReview article

Open Access
File
42 Citations (Scopus)
202 Downloads (Pure)

A qualitative synthesis of gastro-oesophageal reflux in bronchiectasis: Current understanding and future risk

McDonnell, M. J., O'Toole, D., Ward, C., Pearson, J. P., Lordan, J. L., De Soyza, A., Loebinger, M., Chalmers, J. D., Laffey, J. G. & Rutherford, R. M., Aug 2018, In : Respiratory Medicine. 141, p. 132-143 12 p.

Research output: Contribution to journalReview article

Open Access
File
6 Citations (Scopus)
127 Downloads (Pure)
Open Access
File
4 Citations (Scopus)
162 Downloads (Pure)

A systematic review of clinical trial registration in major respiratory journals 2010-2018

Suntila, N. S. M., Smith, A., Al-Dabbagh, Y. & Chalmers, J. D., 6 Dec 2018, In : European Respiratory Journal. 52, 6, 1801491.

Research output: Contribution to journalLetter

Open Access
File
52 Downloads (Pure)

British Thoracic Society guideline for bronchiectasis in adults

Hill, A. T., Sullivan, A. L., Chalmers, J. D., De Soyza, A., Elborn, J. S., Floto, R. A., Grillo, L., Gruffydd-Jones, K., Harvey, A., Haworth, C. S., Hiscocks, E., Hurst, J. R., Johnson, C., Kelleher, W. P., Bedi, P., Payne, K., Saleh, H., Screaton, N. J., Smith, M., Tunney, M. & 3 others, Whitters, D., Wilson, R. & Loebinger, M. R., 1 Dec 2018, In : BMJ Open Respiratory Research. 5, 1, 16 p., e000348.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
119 Downloads (Pure)

Bronchiectasis: an emerging global epidemic

Chotirmall, S. H. & Chalmers, J. D., 22 May 2018, In : BMC Pulmonary Medicine. 18, 1, p. 1-3 3 p., 76.

Research output: Contribution to journalEditorial

Open Access
File
5 Citations (Scopus)
114 Downloads (Pure)

Bronchiectasis: new therapies and new perspectives

Chalmers, J. D. & Chotirmall, S. H., Sep 2018, In : The Lancet Respiratory Medicine. 6, 9, p. 715-726 12 p.

Research output: Contribution to journalReview article

Open Access
File
51 Citations (Scopus)
350 Downloads (Pure)

Bronchiectasis: a case-based approach to investigation and management

Contarini, M., Finch, S. & Chalmers, J. D., 30 Sep 2018, In : European Respiratory Review. 27, 149, p. 1-13 13 p., 180016.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
128 Downloads (Pure)

Bronchiectasis

Chalmers, J. D., Chang, A. B., Chotirmall, S. H., Dhar, R. & McShane, P. J., 15 Nov 2018, In : Nature reviews. Disease primers. 4, 1, 1 p., 45.

Research output: Contribution to journalReview article

12 Citations (Scopus)

Bronchiectasis Exacerbations Are Heart-Breaking

Chalmers, J. D., 1 Mar 2018, In : Annals of the American Thoracic Society. 15, 3, p. 301-303 3 p.

Research output: Contribution to journalEditorial

Open Access
2 Citations (Scopus)

Burden and risk factors for Pseudomonas aeruginosa community-acquired pneumonia: a Multinational Point Prevalence Study of Hospitalised Patients

Restrepo, M. I., Babu, B. L., Reyes, L. F., Chalmers, J. D., Soni, N. J., Sibila, O., Faverio, P., Cilloniz, C., Rodriguez-Cintron, W. & Aliberti, S., 9 Aug 2018, In : European Respiratory Journal. 52, 2, 1701190.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
46 Downloads (Pure)

Burden of pneumococcal community-acquired pneumonia in adults across Europe: A literature review

Torres, A., Cillóniz, C., Blasi, F., Chalmers, J. D., Gaillat, J., Dartois, N., Schmitt, H-J. & Welte, T., Apr 2018, In : Respiratory Medicine. 137, p. 6-13 8 p.

Research output: Contribution to journalReview article

19 Citations (Scopus)

Characterization of the “frequent exacerbator phenotype” in bronchiectasis

Chalmers, J. D., Aliberti, S., Filonenko, A., Shteinberg, M., Goeminne, P. C., Hill, A. T., Fardon, T. C., Obradovic, D., Gerlinger, C., Sotgiu, G., Operschall, E., Rutherford, R. M., Dimakou, K., Polverino, E., De Soyza, A. & McDonnell, M. J., 1 Jun 2018, In : American Journal of Respiratory and Critical Care Medicine. 197, 11, p. 1410-1420 11 p.

Research output: Contribution to journalArticle

Open Access
File
63 Citations (Scopus)
152 Downloads (Pure)

Circulating desmosine as a biomarker of azithromycin treatment response: a post hoc analysis of the COLUMBUS randomised controlled trial

Chalmers, J. D., Djamin, R. S., Schouten, M., Keir, H. R., Tan, B., Aerts, J. G. J. V., Huang, J. T-J. & van der Eerden, M., Oct 2018, In : ERJ Open Research. 4, 4, p. 1-4 4 p.

Research output: Contribution to journalArticle

Open Access
File
95 Downloads (Pure)

Continuous versus intermittent antibiotics for bronchiectasis

Donovan, T., Felix, L. M., Chalmers, J. D., Milan, S. J., Mathioudakis, A. G. & Spencer, S., 3 Jun 2018, In : Cochrane Database of Systematic Reviews. 2018, 6, p. 1-30 30 p., CD012733.

Research output: Contribution to journalReview article

Open Access
File
4 Citations (Scopus)
102 Downloads (Pure)

Cross-infection risk in patients with bronchiectasis: a position statement from the European Bronchiectasis Network (EMBARC), EMBARC/ELF patient advisory group and European Reference Network (ERN-Lung) Bronchiectasis Network

Chalmers, J. D., Ringshausen, F. C., Harris, B., Elborn, J. S., Posthumus, A., Haworth, C. S., Pilkington, N., Polverino, E., Ruddy, T., Aliberti, S., Goeminne, P. C., Winstanley, C. & De Soyza, A., 1 Jan 2018, In : European Respiratory Journal. 51, 1, 6 p., 1701937.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
80 Downloads (Pure)

Economic burden of bronchiectasis in Germany

Diel, R., Chalmers, J. D., Rabe, K. F., Nienhaus, A., Loddenkemper, R. & Ringshausen, F. C., 5 Dec 2018, In : European Respiratory Journal.

Research output: Contribution to journalArticle

Open Access
File

ERS syllabus for postgraduate training in respiratory infections: A guide for comprehensive training

Aliberti, S., Farr, A., Tabin, N., Blasi, F., Torres, A., Woodhead, M., Migliori, G. B., Sotgiu, G., Dimopoulos, G., Chalmers, J. D., Ringshausen, F. C., Loebinger, M. R., Read, R. & Rohde, G., 1 Dec 2018, In : Breathe. 14, 4, p. 269-275 7 p.

Research output: Contribution to journalEditorial

Open Access
File
106 Downloads (Pure)

Genetic mannose binding lectin deficiency is associated with airway microbiota diversity and reduced exacerbation frequency in COPD

Dicker, A. J., Crichton, M. L., Cassidy, A. J., Brady, G., Hapca, A., Tavendale, R., Einarsson, G. G., Furrie, E., Elborn, J. S., Schembri, S., Marshall, S. E., Palmer, C. N. A. & Chalmers, J. D., Jun 2018, In : Thorax. 73, 6, p. 510-518 9 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
146 Downloads (Pure)

Geographic variation in the aetiology, epidemiology and microbiology of bronchiectasis

Chandrasekaran, R., Mac Aogáin, M., Chalmers, J. D., Elborn, S. J. & Chotirmall, S. H., 22 May 2018, In : BMC Pulmonary Medicine. 18, 1, p. 1-14 14 p., 83.

Research output: Contribution to journalReview article

Open Access
File
32 Citations (Scopus)
164 Downloads (Pure)