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Publication Year

  • 2020
  • 2018
  • 2016

Author

  • James Chalmers

ACCORD: A Multicentre, Seamless, Phase 2 Adaptive Randomisation Platform Study to Assess the Efficacy and Safety of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalised Patients: A structured summary of a study protocol for a randomised controlled trial

Wilkinson, T., Dixon, R., Page, C., Carroll, M., Griffiths, G., Ho, L-P., De Soyza, A., Felton, T., Lewis, K. E., Phekoo, K., Chalmers, J. D., Gordon, A., McGarvey, L., Doherty, J., Read, R. C., Shankar-Hari, M., Martinez-Alier, N., O'Kelly, M., Duncan, G., Walles, R. & 3 others, Sykes, J., Summers, C. & Singh, D., 31 Jul 2020, In : Trials. 21, 1, 3 p., 691.

Research output: Contribution to journalArticle

Open Access
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31 Downloads (Pure)

A comprehensive approach to lung function in bronchiectasis

Radovanovic, D., Santus, P., Blasi, F., Sotgiu, G., D'Arcangelo, F., Simonetta, E., Contarini, M., Franceschi, E., Goeminne, P. C., Chalmers, J. D. & Aliberti, S., Dec 2018, In : Respiratory Medicine. 145, p. 120-129 10 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
128 Downloads (Pure)

A cuckoo covid coincidence?

Chalmers, J. D. & Lonergan, M., 9 Sep 2020, In : European Respiratory Journal. 4 p.

Research output: Contribution to journalArticle

Open Access
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13 Downloads (Pure)

Advances in bronchiectasis: endotyping, genetics, microbiome, and disease heterogeneity

Flume, P. A., Chalmers, J. D. & Olivier, K. N., 8 Sep 2018, In : The Lancet. 392, 10150, p. 880-890 11 p.

Research output: Contribution to journalReview article

Open Access
File
45 Citations (Scopus)
246 Downloads (Pure)

Airway Mucin 2 is decreased in patients with severe chronic obstructive pulmonary disease with bacterial colonization

Sibila, O., Garcia-Bellmunt, L., Giner, J., Rodrigo-Troyano, A., Suarez-Cuartin, G., Torrego, A., Castillo, D., Solanes, I., Mateus, E. F., Vidal, S., Sanchez-Reus, F., Sala, E., Cosio, B. G., Restrepo, M. I., Anzueto, A., Chalmers, J. D. & Plaza, V., 1 May 2016, In : Annals of the American Thoracic Society. 13, 5, p. 636-642 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

A membrane-depolarizing toxin substrate of the Staphylococcus aureus type VII secretion system mediates intraspecies competition

Ulhuq, F. R., Gomes, M. C., Duggan, G. M., Guo, M., Mendonca, C., Buchanan, G., Chalmers, J. D., Cao, Z., Kneuper, H., Murdoch, S., Thomson, S., Strahl, H., Trost, M., Mostowy, S. & Palmer, T., 25 Aug 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 34, p. 20836-20847 12 p.

Research output: Contribution to journalArticle

Open Access
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10 Downloads (Pure)

A qualitative synthesis of gastro-oesophageal reflux in bronchiectasis: Current understanding and future risk

McDonnell, M. J., O'Toole, D., Ward, C., Pearson, J. P., Lordan, J. L., De Soyza, A., Loebinger, M., Chalmers, J. D., Laffey, J. G. & Rutherford, R. M., Aug 2018, In : Respiratory Medicine. 141, p. 132-143 12 p.

Research output: Contribution to journalReview article

Open Access
File
6 Citations (Scopus)
152 Downloads (Pure)
Open Access
File
6 Citations (Scopus)
178 Downloads (Pure)

A systematic review of clinical trial registration in major respiratory journals 2010-2018

Suntila, N. S. M., Smith, A., Al-Dabbagh, Y. & Chalmers, J. D., 6 Dec 2018, In : European Respiratory Journal. 52, 6, 1801491.

Research output: Contribution to journalLetter

Open Access
File
77 Downloads (Pure)

A systematic review of the burden of vaccine preventable pneumococcal disease in UK adults

Chalmers, J. D., Dicker, A., Woodhead, M. & Madhava, H., 11 May 2016, In : BMC Pulmonary Medicine. 16, 1, p. 1-11 11 p., 77.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
209 Downloads (Pure)

Blood eosinophils as a biomarker of future COPD exacerbation risk: pooled data from 11 clinical trials

Singh, D., Wedzicha, J. A., Siddiqui, S., de la Hoz, A., Xue, W., Magnussen, H., Miravitlles, M., Chalmers, J. D. & Calverley, P. M. A., 17 Sep 2020, In : Respiratory Research. 21, 10 p., 240.

Research output: Contribution to journalArticle

Open Access
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Blood neutrophil counts are associated with exacerbation frequency and mortality in COPD

Lonergan, M., Dicker, A. J., Crichton, M. L., Keir, H. R., Van Dyke, M. K., Mullerova, H., Miller, B. E., Tal-Singer, R. & Chalmers, J. D., 1 Jul 2020, In : Respiratory Research. 21, p. 1-10 10 p., 166.

Research output: Contribution to journalArticle

Open Access
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13 Downloads (Pure)

British Thoracic Society guideline for bronchiectasis in adults

Hill, A. T., Sullivan, A. L., Chalmers, J. D., De Soyza, A., Elborn, J. S., Floto, R. A., Grillo, L., Gruffydd-Jones, K., Harvey, A., Haworth, C. S., Hiscocks, E., Hurst, J. R., Johnson, C., Kelleher, W. P., Bedi, P., Payne, K., Saleh, H., Screaton, N. J., Smith, M., Tunney, M. & 3 others, Whitters, D., Wilson, R. & Loebinger, M. R., 1 Dec 2018, In : BMJ Open Respiratory Research. 5, 1, 16 p., e000348.

Research output: Contribution to journalArticle

Open Access
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5 Citations (Scopus)
133 Downloads (Pure)

Bronchiectasis

Chalmers, J. D., Chang, A. B., Chotirmall, S. H., Dhar, R. & McShane, P. J., 15 Nov 2018, In : Nature reviews. Disease primers. 4, 1, 1 p., 45.

Research output: Contribution to journalReview article

18 Citations (Scopus)

Bronchiectasis: a case-based approach to investigation and management

Contarini, M., Finch, S. & Chalmers, J. D., 30 Sep 2018, In : European Respiratory Review. 27, 149, p. 1-13 13 p., 180016.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
142 Downloads (Pure)

Bronchiectasis: an emerging global epidemic

Chotirmall, S. H. & Chalmers, J. D., 22 May 2018, In : BMC Pulmonary Medicine. 18, 1, p. 1-3 3 p., 76.

Research output: Contribution to journalEditorial

Open Access
File
6 Citations (Scopus)
128 Downloads (Pure)

Bronchiectasis: new therapies and new perspectives

Chalmers, J. D. & Chotirmall, S. H., Sep 2018, In : The Lancet Respiratory Medicine. 6, 9, p. 715-726 12 p.

Research output: Contribution to journalReview article

Open Access
File
54 Citations (Scopus)
424 Downloads (Pure)

Bronchiectasis Exacerbations Are Heart-Breaking

Chalmers, J. D., 1 Mar 2018, In : Annals of the American Thoracic Society. 15, 3, p. 301-303 3 p.

Research output: Contribution to journalEditorial

Open Access
2 Citations (Scopus)

Burden and risk factors for Pseudomonas aeruginosa community-acquired pneumonia: a Multinational Point Prevalence Study of Hospitalised Patients

Restrepo, M. I., Babu, B. L., Reyes, L. F., Chalmers, J. D., Soni, N. J., Sibila, O., Faverio, P., Cilloniz, C., Rodriguez-Cintron, W. & Aliberti, S., 9 Aug 2018, In : European Respiratory Journal. 52, 2, 1701190.

Research output: Contribution to journalArticle

Open Access
File
23 Citations (Scopus)
59 Downloads (Pure)

Burden of pneumococcal community-acquired pneumonia in adults across Europe: A literature review

Torres, A., Cillóniz, C., Blasi, F., Chalmers, J. D., Gaillat, J., Dartois, N., Schmitt, H-J. & Welte, T., Apr 2018, In : Respiratory Medicine. 137, p. 6-13 8 p.

Research output: Contribution to journalReview article

20 Citations (Scopus)

Cardiovascular disease as a complication of community-acquired pneumonia

Rae, N., Finch, S. & Chalmers, J. D., May 2016, In : Current Opinion in Pulmonary Medicine. 22, 3, p. 212-218 7 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Changes in respiratory symptoms during 48 weeks treatment with ARD-3150 (inhaled liposomal ciprofloxacin) in bronchiectasis: results from the ORBIT-3 and -4 studies

Chalmers, J. D., Cipolla, D., Thompson, B., Davis, A. M., O'Donnell, A., Tino, G., Gonda, I., Haworth, C. & Froehlich, J., 18 Jun 2020, In : European Respiratory Journal. 55, 6

Research output: Contribution to journalArticle

Characterization of bronchiectasis in the elderly

Bellelli, G., Chalmers, J. D., Sotgiu, G., Dore, S., McDonnell, M. J., Goeminne, P. C., Dimakou, K., Skrbic, D., Lombi, A., Pane, F., Obradovic, D., Fardon, T. C., Rutherford, R. M., Pesci, A. & Aliberti, S., Oct 2016, In : Respiratory Medicine. 119, p. 13-19 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
292 Downloads (Pure)

Characterization of the “frequent exacerbator phenotype” in bronchiectasis

Chalmers, J. D., Aliberti, S., Filonenko, A., Shteinberg, M., Goeminne, P. C., Hill, A. T., Fardon, T. C., Obradovic, D., Gerlinger, C., Sotgiu, G., Operschall, E., Rutherford, R. M., Dimakou, K., Polverino, E., De Soyza, A. & McDonnell, M. J., 1 Jun 2018, In : American Journal of Respiratory and Critical Care Medicine. 197, 11, p. 1410-1420 11 p.

Research output: Contribution to journalArticle

Open Access
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68 Citations (Scopus)
170 Downloads (Pure)

Characterizing non-tuberculous mycobacteria infection in bronchiectasis

Faverio, P., Stainer, A., Bonaiti, G., Zucchetti, S. C., Simonetta, E., Lapadula, G., Marruchella, A., Gori, A., Blasi, F., Codecasa, L., Pesci, A., Chalmers, J. D., Loebinger, M. R. & Aliberti, S., 16 Nov 2016, In : International Journal of Molecular Sciences. 17, 11, 12 p., 1913.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
141 Downloads (Pure)

Circulating desmosine as a biomarker of azithromycin treatment response: a post hoc analysis of the COLUMBUS randomised controlled trial

Chalmers, J. D., Djamin, R. S., Schouten, M., Keir, H. R., Tan, B., Aerts, J. G. J. V., Huang, J. T-J. & van der Eerden, M., Oct 2018, In : ERJ Open Research. 4, 4, p. 1-4 4 p.

Research output: Contribution to journalArticle

Open Access
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104 Downloads (Pure)

Clinical phenotypes in adult patients with bronchiectasis

Aliberti, S., Lonni, S., Dore, S., McDonnell, M. J., Goeminne, P. C., Dimakou, K., Fardon, T., Rutherford, R., Pesci, A., Restrepo, M. I., Sotgiu, G. & Chalmers, J., 1 Apr 2016, In : European Respiratory Journal. 47, 4, p. 1113-1122 10 p.

Research output: Contribution to journalArticle

Open Access
File
123 Citations (Scopus)
144 Downloads (Pure)

Clinical phenotypes in bronchiectasis: Right on track to develop precision medicine in respiratory diseases

Sotgiu, G., Dore, S., Chalmers, J. D. & Aliberti, S., 1 May 2016, In : International Journal of Tuberculosis and Lung Disease. 20, 5, p. 709 1 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Community-Acquired Pneumonia: A Global Perspective

Feldman, C. & Chalmers, J. D., Dec 2016, In : Seminars in Respiratory and Critical Care Medicine. 37, 6, p. 797-798 2 p.

Research output: Contribution to journalEditorial

Open Access
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1 Citation (Scopus)
172 Downloads (Pure)

Community-acquired pneumonia related to intracellular pathogens

Cillóniz, C., Torres, A., Niederman, M., van der Eerden, M., Chalmers, J., Welte, T. & Blasi, F., Sep 2016, In : Intensive Care Medicine. 42, 9, p. 1374-1386 13 p.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
417 Downloads (Pure)

Comorbidities and the risk of mortality in patients with bronchiectasis: an international mulitcentre cohort study

McDonnell, M. J., Aliberti, S., Goeminne, P. C., Restrepo, M. I., Finch, S., Pesci, A., Dupont, L., Fardon, T., Wilson, R., Loebinger, M., Skrbic, D., Obradovic, D., De Soyza, A., Ward, C., Laffey, J. G., Rutherford, R. & Chalmers, J., Dec 2016, In : The Lancet Respiratory Medicine. 4, 12, p. 969-979 11 p.

Research output: Contribution to journalArticle

Open Access
File
86 Citations (Scopus)
166 Downloads (Pure)

Continuous versus intermittent antibiotics for bronchiectasis

Donovan, T., Felix, L. M., Chalmers, J. D., Milan, S. J., Mathioudakis, A. G. & Spencer, S., 3 Jun 2018, In : Cochrane Database of Systematic Reviews. 2018, 6, p. 1-30 30 p., CD012733.

Research output: Contribution to journalReview article

Open Access
File
4 Citations (Scopus)
118 Downloads (Pure)

Corticosteroids for community-acquired pneumonia: a critical view of the evidence

Chalmers, J. D., 1 Oct 2016, In : European Respiratory Journal. 48, 4, p. 984-986 3 p.

Research output: Contribution to journalEditorial

10 Citations (Scopus)

Counting the cost of bronchiectasis

Gao, Y-H. & Chalmers, J. D., 30 Jun 2020, In : Respirology . 2 p.

Research output: Contribution to journalEditorial

Cross-infection risk in patients with bronchiectasis: a position statement from the European Bronchiectasis Network (EMBARC), EMBARC/ELF patient advisory group and European Reference Network (ERN-Lung) Bronchiectasis Network

Chalmers, J. D., Ringshausen, F. C., Harris, B., Elborn, J. S., Posthumus, A., Haworth, C. S., Pilkington, N., Polverino, E., Ruddy, T., Aliberti, S., Goeminne, P. C., Winstanley, C. & De Soyza, A., 1 Jan 2018, In : European Respiratory Journal. 51, 1, 6 p., 1701937.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
94 Downloads (Pure)

Cystic fibrosis lung disease and bronchiectasis

Chalmers, J. D., Jan 2020, In : The Lancet Respiratory Medicine. 8, 1, p. 12-14 3 p.

Research output: Contribution to journalComment/debate

Open Access
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44 Downloads (Pure)

Development and initial validation of the bronchiectasis exacerbation and symptom tool (BEST)

Artaraz, A., Crichton, M. L., Finch, S., Abo-Leyah, H., Goeminne, P., Aliberti, S., Fardon, T. & Chalmers, J. D., 13 Jan 2020, In : Respiratory Research. 21, 1, p. 1-9 1 p., 18.

Research output: Contribution to journalArticle

Open Access
File
46 Downloads (Pure)

Development and Reporting of Prediction Models: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals

Leisman, D. E., Harhay, M. O., Lederer, D. J., Abramson, M., Adjei, A. A., Bakker, J., Ballas, Z. K., Barreiro, E., Bell, S. C., Bellomo, R., Bernstein, J. A., Branson, R. D., Brusasco, V., Chalmers, J. D., Chokroverty, S., Citerio, G., Collop, N. A., Cooke, C. R., Crapo, J. D., Donaldson, G. & 19 others, Fitzgerald, D. A., Grainger, E., Hale, L., Herth, F. J., Kochanek, P. M., Marks, G., Moorman, J. R., Ost, D. E., Schatz, M., Sheikh, A., Smyth, A. R., Stewart, I., Stewart, P. W., Swenson, E. R., Szymusiak, R., Teboul, J-L., Vincent, J-L., Wedzicha, J. A. & Maslove, D. M., May 2020, In : Critical Care Medicine. 48, 5, p. 623-633 11 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
167 Downloads (Pure)

Development of Drugs for Nontuberculous Mycobacterial Disease: Clinicians' Interpretation of a US FDA Workshop

Flume, P. A., Griffith, D. E., Chalmers, J. D., Daley, C. L., Olivier, K., O'Donnell, A., Aksamit, T., Kasperbauer, S., Leitman, A. & Winthrop, K. L., 24 Aug 2020, In : Chest.

Research output: Contribution to journalReview article

Diagnostic challenges of bronchiectasis

Suarez-Cuartin, G., Chalmers, J. D. & Sibila, O., 1 Jul 2016, In : Respiratory Medicine. 116, p. 70-77 8 p.

Research output: Contribution to journalReview article

Open Access
File
16 Citations (Scopus)
180 Downloads (Pure)

Drive-through testing for SARS-CoV-2 in symptomatic health and social care workers and household members: an observational cohort study

Parcell, B., Brechin, K., Allstaff, S., Park, M., Third, W., Bean, S., Hind, C., Farmer, R. & Chalmers, J. D., 27 Aug 2020, In : Thorax. 3 p.

Research output: Contribution to journalArticle

Open Access
File
43 Downloads (Pure)

Economic burden of bronchiectasis in Germany

Diel, R., Chalmers, J. D., Rabe, K. F., Nienhaus, A., Loddenkemper, R. & Ringshausen, F. C., 5 Dec 2018, In : European Respiratory Journal.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
19 Downloads (Pure)

Efficacy and safety of TOBI Podhaler® in Pseudomonas aeruginosa-infected bronchiectasis patients: iBEST study

Loebinger, M. R., Polverino, E., Chalmers, J. D., Tiddens, H. A. W. M., Goossens, H., Ringhausen, F. C., Tunney, M., Hill, A. T., Pathan, R., Angyalosi, G., Blasi, F., Elborn, S. J. & Haworth, C. S., 27 Aug 2020, In : European Respiratory Journal.

Research output: Contribution to journalArticle

Empirical coverage of methicillin-resistant Staphylococcus aureus in community-acquired pneumonia: those who do not remember the past are doomed to repeat it

Chalmers, J. D., Reyes, L. F., Aliberti, S. & Restrepo, M. I., 15 Oct 2016, In : Clinical Infectious Diseases. 63, 8, p. 1145-1146 1 p.

Research output: Contribution to journalLetter

8 Citations (Scopus)
16 Downloads (Pure)

Endothelial adhesion molecules and multiple organ failure in patients with severe sepsis

Amalakuhan, B., Habib, S. A., Mangat, M., Reyes, L. F., Rodriguez, A. H., Hinojosa, C. A., Soni, N. J., Gilley, R. P., Bustamante, C. A., Anzueto, A., Levine, S. M., Peters, J. I., Aliberti, S., Sibila, O., Chalmers, J. D., Torres, A., Waterer, G. W., Martin-Loeches, I., Bordon, J., Blanquer, J. & 15 others, Sanz, F., Marcos, P. J., Rello, J., Ramirez, J., Solé-Violán, J., Luna, C. M., Feldman, C., Witzenrath, M., Wunderink, R. G., Stolz, D., Wiemken, T. L., Shindo, Y., Dela Cruz, C. S., Orihuela, C. J. & Restrepo, M. I., Dec 2016, In : Cytokine. 88, p. 267-273 7 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
128 Downloads (Pure)

ERS syllabus for postgraduate training in respiratory infections: A guide for comprehensive training

Aliberti, S., Farr, A., Tabin, N., Blasi, F., Torres, A., Woodhead, M., Migliori, G. B., Sotgiu, G., Dimopoulos, G., Chalmers, J. D., Ringshausen, F. C., Loebinger, M. R., Read, R. & Rohde, G., 1 Dec 2018, In : Breathe. 14, 4, p. 269-275 7 p.

Research output: Contribution to journalEditorial

Open Access
File
119 Downloads (Pure)
Open Access
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1 Citation (Scopus)
8 Downloads (Pure)

Evaluation of serum inflammatory biomarkers as predictors of treatment outcome in pulmonary tuberculosis

Singanayagam, A., Manalan, K., Connell, D. W., Chalmers, J. D., Sridhar, S., Ritchie, A. I., Lalvani, A., Wickremasinghe, M. & Kon, O. M., 1 Dec 2016, In : International Journal of Tuberculosis and Lung Disease. 20, 12, p. 1653-1660 8 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
149 Downloads (Pure)