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• 2020

  ACCORD: A Multicentre, Seamless, Phase 2 Adaptive Randomisation Platform Study to Assess the Efficacy and Safety of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalised Patients: A structured summary of a study protocol for a randomised controlled trial

  Wilkinson, T., Dixon, R., Page, C., Carroll, M., Griffiths, G., Ho, L-P., De Soyza, A., Felton, T., Lewis, K. E., Phekoo, K., Chalmers, J. D., Gordon, A., McGarvey, L., Doherty, J., Read, R. C., Shankar-Hari, M., Martinez-Alier, N., O'Kelly, M., Duncan, G., Walles, R. & 3 others, Sykes, J., Summers, C. & Singh, D., 31 Jul 2020, In: Trials. 21, 1, 3 p., 691.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Random Allocation
  • Randomized Controlled Trials
  • acalabrutinib
  • Safety
  • Standard of Care
  5 Citations (Scopus)

  44 Downloads (Pure)

• A cuckoo covid coincidence?

  Chalmers, J. D. & Lonergan, M., 15 Oct 2020, In: European Respiratory Journal. 56, 4, 4 p., 2003236.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File
  69 Downloads (Pure)

• A high-risk airway mycobiome is associated with frequent exacerbation and mortality in COPD

  Tiew, P. Y., Dicker, A. J., Keir, H. R., Poh, M. E., Pang, S. L., Mac Aogáin, M., Chua Qi Yu, B., Tan, J. L., Xu, H., Koh, M. S., Tee, A., Abisheganaden, J. A., Chew, F. T., Miller, B. E., Tal-Singer, R., Chalmers, J. D. & Chotirmall, S. H., 24 Sep 2020, In: European Respiratory Journal.

  Research output: Contribution to journal › Article › peer-review

  • Mycobiome
  • Chronic Obstructive Pulmonary Disease
  • Mortality
  • Immunoglobulin E
  • Fungi

• A membrane-depolarizing toxin substrate of the Staphylococcus aureus type VII secretion system mediates intraspecies competition

  Ulhuq, F. R., Gomes, M. C., Duggan, G. M., Guo, M., Mendonca, C., Buchanan, G., Chalmers, J. D., Cao, Z., Kneuper, H., Murdoch, S., Thomson, S., Strahl, H., Trost, M., Mostowy, S. & Palmer, T., 25 Aug 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 34, p. 20836-20847 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Type VII Secretion Systems
  • Staphylococcus aureus
  • Membranes
  • Zebrafish
  • Protein Translocation Systems
  2 Citations (Scopus)

  14 Downloads (Pure)

• Blood eosinophils as a biomarker of future COPD exacerbation risk: pooled data from 11 clinical trials

  Singh, D., Wedzicha, J. A., Siddiqui, S., de la Hoz, A., Xue, W., Magnussen, H., Miravitlles, M., Chalmers, J. D. & Calverley, P. M. A., 17 Sep 2020, In: Respiratory Research. 21, 10 p., 240.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Eosinophils
  • Chronic Obstructive Pulmonary Disease
  • Disease Progression
  • Biomarkers
  • Clinical Trials
  19 Downloads (Pure)

• Blood neutrophil counts are associated with exacerbation frequency and mortality in COPD

  Lonergan, M., Dicker, A. J., Crichton, M. L., Keir, H. R., Van Dyke, M. K., Mullerova, H., Miller, B. E., Tal-Singer, R. & Chalmers, J. D., 1 Jul 2020, In: Respiratory Research. 21, p. 1-10 10 p., 166.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Chronic Obstructive Pulmonary Disease
  • Neutrophils
  • Mortality
  • Microbiota
  • Eosinophils
  1 Citation (Scopus)

  20 Downloads (Pure)

• Changes in respiratory symptoms during 48 weeks treatment with ARD-3150 (inhaled liposomal ciprofloxacin) in bronchiectasis: results from the ORBIT-3 and -4 studies

  Chalmers, J. D., Cipolla, D., Thompson, B., Davis, A. M., O'Donnell, A., Tino, G., Gonda, I., Haworth, C. & Froehlich, J., 22 Oct 2020, In: European Respiratory Journal. 55, 6, 2000110.

  Research output: Contribution to journal › Article › peer-review

  • Bronchiectasis
  • Ciprofloxacin
  • Bacterial Load
  • Therapeutics
  • Quality of Life

• Characteristics and Outcomes of Health and Social Care workers testing positive for SARS-CoV-2 in the Tayside region of Scotland

  Siddiqui, M. K., Parcell, B., Allstaff, S., Palmer, C., Chalmers, J. & Bell, S., 1 Sep 2020, In: European Respiratory Journal. 56, 3, 2 p., 2002568.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File
  1 Citation (Scopus)

  13 Downloads (Pure)

• Clinical and financial burden of hospitalised community-acquired pneumonia in patients with selected underlying comorbidities in England

  Campling, J., Jones, D., Chalmers, J., Jiang, Q., Vyse, A., Madhava, H., Ellsbury, G., Rabe, A. & Slack, M., 13 Oct 2020, In: BMJ Open Respiratory Research. 7, 1, 10 p., e000703.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • England
  • Pneumonia
  • Comorbidity
  • Chronic Disease
  • Diabetes Mellitus
  30 Downloads (Pure)

• Clinical endotypes of exacerbation are associated with differences in microbial composition and diversity in COPD

  Keir, H. R., Dicker, A., Lonergan, M., Crichton, M., Miller, B. E., Tal-Singer, R. & Chalmers, J. D., 1 Oct 2020, In: European Respiratory Journal. 56, 4, 2000391.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Counting the cost of bronchiectasis

  Gao, Y-H. & Chalmers, J. D., 30 Jun 2020, In: Respirology . 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• CXCL-8-dependent and -independent neutrophil activation in COPD: experiences from a pilot study of the CXCR2 antagonist danirixin

  Keir, H. R., Richardson, H., Fillmore, C., Shoemark, A., Lazaar, A. L., Miller, B. E., Tal-Singer, R., Chalmers, J. D. & Mohan, D., 10 Nov 2020, In: ERJ Open Research. 6, 4, 4 p., 00583-2020.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Neutrophil Activation
  • Interleukin-8
  • Chronic Obstructive Pulmonary Disease
  23 Downloads (Pure)

• Cystic fibrosis lung disease and bronchiectasis

  Chalmers, J. D., Jan 2020, In: The Lancet Respiratory Medicine. 8, 1, p. 12-14 3 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  File
  1 Citation (Scopus)

  67 Downloads (Pure)

• Development and initial validation of the bronchiectasis exacerbation and symptom tool (BEST)

  Artaraz, A., Crichton, M. L., Finch, S., Abo-Leyah, H., Goeminne, P., Aliberti, S., Fardon, T. & Chalmers, J. D., 13 Jan 2020, In: Respiratory Research. 21, 1, 9 p., 18.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Bronchiectasis
  • Diary
  • Sputum
  • Cough
  • Chronic Obstructive Pulmonary Disease
  55 Downloads (Pure)

• Development and Reporting of Prediction Models: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals

  Leisman, D. E., Harhay, M. O., Lederer, D. J., Abramson, M., Adjei, A. A., Bakker, J., Ballas, Z. K., Barreiro, E., Bell, S. C., Bellomo, R., Bernstein, J. A., Branson, R. D., Brusasco, V., Chalmers, J. D., Chokroverty, S., Citerio, G., Collop, N. A., Cooke, C. R., Crapo, J. D., Donaldson, G. & 19 others, Fitzgerald, D. A., Grainger, E., Hale, L., Herth, F. J., Kochanek, P. M., Marks, G., Moorman, J. R., Ost, D. E., Schatz, M., Sheikh, A., Smyth, A. R., Stewart, I., Stewart, P. W., Swenson, E. R., Szymusiak, R., Teboul, J-L., Vincent, J-L., Wedzicha, J. A. & Maslove, D. M., May 2020, In: Critical Care Medicine. 48, 5, p. 623-633 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Practice Guidelines
  • Critical Care
  • Sleep
  • Medicine
  • Guidelines
  17 Citations (Scopus)

  182 Downloads (Pure)

• Development of Drugs for Nontuberculous Mycobacterial Disease: Clinicians' Interpretation of a US FDA Workshop

  Flume, P. A., Griffith, D. E., Chalmers, J. D., Daley, C. L., Olivier, K., O'Donnell, A., Aksamit, T., Kasperbauer, S., Leitman, A. & Winthrop, K. L., 24 Aug 2020, In: Chest.

  Research output: Contribution to journal › Review article › peer-review

  • Drug Development
  • Education
  • Lung Diseases
  • Outcome Assessment (Health Care)
  • Clinical Trials

• Drive-through testing for SARS-CoV-2 in symptomatic health and social care workers and household members: an observational cohort study

  Parcell, B., Brechin, K., Allstaff, S., Park, M., Third, W., Bean, S., Hind, C., Farmer, R. & Chalmers, J. D., 1 Dec 2020, In: Thorax. 75, 12, p. 1109-1111 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Severe Acute Respiratory Syndrome
  • Coronavirus
  • Pandemics
  • Observational Studies
  • Coronavirus Infections
  56 Downloads (Pure)

• Efficacy and safety of TOBI Podhaler® in Pseudomonas aeruginosa-infected bronchiectasis patients: iBEST study

  Loebinger, M. R., Polverino, E., Chalmers, J. D., Tiddens, H. A. W. M., Goossens, H., Ringhausen, F. C., Tunney, M., Hill, A. T., Pathan, R., Angyalosi, G., Blasi, F., Elborn, S. J. & Haworth, C. S., 27 Aug 2020, In: European Respiratory Journal.

  Research output: Contribution to journal › Article › peer-review

  • Tobramycin
  • Bronchiectasis
  • Powders
  • Pseudomonas aeruginosa
  • Inhalation

• Estimates of the ongoing need for social distancing and control measures post-"lockdown" from trajectories of COVID-19 cases and mortality

  Lonergan, M. & Chalmers, J. D., 23 Jul 2020, In: European Respiratory Journal. 56, 1, 10 p., 2001483.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Coronavirus
  • France
  • Disease Outbreaks
  • Severe Acute Respiratory Syndrome
  • Mortality
  8 Citations (Scopus)

  17 Downloads (Pure)

• European Respiratory Society International Congress, Madrid, 2019: nontuberculous mycobacterial pulmonary disease highlights

  Chalmers, J. D., Balavoine, C., Castellotti, P. F., Hügel, C., Payet, A., Wat, D. & Rohde, G., Oct 2020, In: ERJ Open Research. 6, 4, 8 p., 00317-2020.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Lung Diseases
  • Spain
  22 Downloads (Pure)

• Genetic and pharmacological relationship between P-Glycoprotein and increased cardiovascular risk associated with clarithromycin prescription: An Epidemiological and Genomic Population-Based Cohort Study in Scotland, UK

  Mordi, I. R., Chan, B., Yanez, N. D., Palmer, C. N. A., Lang, C. C. & Chalmers, J. D., 23 Nov 2020, In: PLoS Medicine. 17, 11, 16 p., e1003372.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Metagenomics
  • Clarithromycin
  • Scotland
  • ATP Binding Cassette Transporter, Subfamily B, Member 1
  • Prescriptions
  30 Downloads (Pure)

• Happy Birthday Bronchiectasis: 200 Years of Targeting Mucus

  Chalmers, J. D. & Sibila, O., 15 Mar 2020, In: American Journal of Respiratory and Critical Care Medicine. 201, 6, p. 639-640 2 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

  File
  31 Downloads (Pure)

• Increased Chitotriosidase Is Associated With Aspergillus and Frequent Exacerbations in South-East Asian Patients With Bronchiectasis

  Poh, T. Y., Tiew, P. Y., Hou Lim, A. Y., Thng, K. X., Binte Mohamed Ali, N. A., Narayana, J. K., Aogáin, M. M., Tien, Z., Chew, W. M., Wai Chan, A. K., Keir, H. R., Dicker, A. J., Hassan, T. M., Xu, H., Tee, A. K. H., Ong, T. H., Koh, M. S., Abisheganaden, J. A., Chalmers, J. D. & Chotirmall, S. H., Aug 2020, In: Chest. 158, 2, p. 512-522 11 p.

  Research output: Contribution to journal › Article › peer-review

  • chitotriosidase
  • Bronchiectasis
  • Aspergillus
  • Chitinases
  • Chronic Obstructive Pulmonary Disease
  3 Citations (Scopus)

• Inhaled Aztreonam improves symptoms of cough and sputum production in patients with bronchiectasis: a post-hoc analysis of the AIR-BX studies

  Crichton, M. L., Lonergan, M., Barker, A. F., Sibila, O., Goeminne, P., Shoemark, A. & Chalmers, J. D., 16 Jul 2020, In: European Respiratory Journal. 56, 1

  Research output: Contribution to journal › Article › peer-review

  • Aztreonam
  • Bronchiectasis
  • Sputum
  • Cough
  • Color

• International perspective on the new 2019 ATS/IDSA CAP guideline - a critical appraisal by a global expert panel

  Pletz, M. W., Blasi, F., Chalmers, J. D., Dela Cruz, C. S., Feldman, C., Luna, C. M., Ramirez, J. A., Shindo, Y., Stolz, D., Torres, A., Webb, B., Welte, T., Wunderink, R. & Aliberti, S., 25 Aug 2020, In: Chest. 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Internationality
  • Communicable Diseases
  • Pneumonia
  • Thorax
  • Guidelines

• Is bronchiectasis really a disease?

  Shteinberg, M., Flume, P. A. & Chalmers, J. D., 31 Mar 2020, In: European Respiratory Review. 29, 155, p. 1-10 10 p., 190051.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Bronchiectasis
  • Signs and Symptoms
  • Clinical Trials
  • Phenotype
  • Inflammation
  64 Downloads (Pure)

• "Management of Community-Acquired Pneumonia in Immunocompromised Adults: A Consensus Statement Regarding Initial Strategies"

  Ramirez, J. A., Musher, D. M., Evans, S. E., Dela Cruz, C., Crothers, K. A., Hage, C. A., Aliberti, S., Anzueto, A., Arancibia, F., Arnold, F., Azoulay, E., Blasi, F., Bordon, J., Burdette, S., Cao, B., Cavallazzi, R., Chalmers, J., Charles, P., Chastre, J., Claessens, Y-E. & 26 others, Dean, N., Duval, X., Fartoukh, M., Feldman, C., File, T., Froes, F., Furmanek, S., Gnoni, M., Lopardo, G., Luna, C., Maruyama, T., Menendez, R., Metersky, M., Mildvan, D., Mortensen, E., Niederman, M. S., Pletz, M., Rello, J., Restrepo, M. I., Shindo, Y., Torres, A., Waterer, G., Webb, B., Welte, T., Witzenrath, M. & Wunderink, R., 16 Jun 2020, In: Chest.

  Research output: Contribution to journal › Review article › peer-review

  • Immunocompromised Host
  • Pneumonia
  • Guidelines
  • Physicians
  • Therapeutics

• Managing and preventing exacerbation of bronchiectasis

  Abo-Leyah, H. & Chalmers, J. D., Apr 2020, In: Current Opinion in Infectious Diseases. 33, 2, p. 189-196 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Bronchiectasis
  • Macrolides
  • Anti-Bacterial Agents
  • Health Care Costs
  • Quality of Life

• Multiple breath washout in bronchiectasis clinical trials: is it feasible?

  O'Neill, K., Ferguson, K., Cosgrove, D., Tunney, M. M., De Soyza, A., Carroll, M., Chalmers, J. D., Gatheral, T., Hill, A. T., Hurst, J. R., Johnson, C., Loebinger, M. R., Angyalosi, G., Haworth, C. S., Jensen, R., Ratjen, F., Saunders, C., Short, C., Davies, J. C., Elborn, J. S. & 1 others, Bradley, J. M., 13 Oct 2020, In: ERJ Open Research. 6, 4, 10 p., 00363-2019.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Bronchiectasis
  • Certification
  • Clinical Trials
  • Reading
  • Data Accuracy
  28 Downloads (Pure)

• Pandemic trials: evidence-based medicine on steroids

  Chalmers, J. D., Dec 2020, In: European Respiratory Journal. 56, 6, 4 p., 2004116.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Evidence-Based Medicine
  • Pandemics
  • Steroids
  • Proof of Concept Study
  • Therapeutics
  9 Downloads (Pure)

• Phase 2 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis

  Chalmers, J. D., Haworth, C. S., Metersky, M. L., Loebinger, M. R., Blasi, F., Sibila, O., O'Donnell, A. E., Sullivan, E. J., Mange, K. C., Fernandez, C., Zou, J., Daley, C. L. & WILLOW Investigators, 7 Sep 2020, In: New England Journal of Medicine. 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Dipeptidyl-Peptidases and Tripeptidyl-Peptidases
  • Bronchiectasis
  • Protease Inhibitors
  • Placebos
  • Leukocyte Elastase

• Providing answers to respiratory patients’ questions during covid-19

  Denning, J., Powell, P. & Chalmers, J. D., 2 Dec 2020, In: Breathe. 16, 3, 4 p., 200219.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Lung
  • Language
  • Health
  38 Downloads (Pure)

• Relationship between Symptoms, Exacerbations, and Treatment Response in Bronchiectasis

  Gao, Y-H., Abo Leyah, H., Finch, S., Lonergan, M., Aliberti, S., De Soyza, A., Fardon, T. C., Tino, G. & Chalmers, J. D., 15 Jun 2020, In: American Journal of Respiratory and Critical Care Medicine. 201, 12, p. 1499-1507 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Bronchiectasis
  • Mannitol
  • Confidence Intervals
  • Therapeutics
  • Scotland
  2 Citations (Scopus)

• Rewiring the Immune Response in COVID-19

  Chalmers, J. D. & Chotirmall, S. H., 15 Sep 2020, In: American Journal of Respiratory and Critical Care Medicine. 202, 6, p. 784-786 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  17 Downloads (Pure)

• Serum Desmosine is Associated with Long-term All-cause and Cardiovascular Mortality in Bronchiectasis

  Huang, J. T-J., Kuzmanova, E., Dicker, A. J., Keir, H. R., Finch, S., Aliberti, S., Fardon, T. C. & Chalmers, J. D., 15 Sep 2020, In: American Journal of Respiratory and Critical Care Medicine. 202, 6, p. 897-899 3 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Sputum neutrophil elastase associates with microbiota and Pseudomonas aeruginosa in bronchiectasis

  Oriano, M., Gramegna, A., Terranova, L., Sotgiu, G., Sulaiman, I., Ruggiero, L., Saderi, L., Wu, B., Chalmers, J. D., Segal, L. N., Marchisio, P., Blasi, F. & Aliberti, S., 22 Oct 2020, In: European Respiratory Journal. 56, 2000769.

  Research output: Contribution to journal › Article › peer-review

  • Leukocyte Elastase
  • Bronchiectasis
  • Microbiota
  • Sputum
  • Pseudomonas aeruginosa
  2 Citations (Scopus)

• Sputum neutrophil elastase in bronchiectasis: a Southern European cohort study

  Gramegna, A., Aliberti, S., Sibila, O., Di Francesco, C., Sotgiu, G., Perea, L., Terranova, L., Oriano, M., Pilocane, T., Saderi, L., Chalmers, J. D., Marchisio, P. & Blasi, F., 25 Jun 2020, In: European Respiratory Journal. 56, 1

  Research output: Contribution to journal › Article › peer-review

  • Leukocyte Elastase
  • Bronchiectasis
  • Sputum
  • Cohort Studies
  • Extracellular Traps

• The evolution of the European Respiratory Journal: ready for the new decade!

  Chalmers, J. D., Reeves, E. L., Bullen, N. J. & Kolb, M., Jan 2020, In: European Respiratory Journal. 55, 1, p. 1-4 4 p., 1902503.

  Research output: Contribution to journal › Editorial › peer-review

• The microbiome in bronchiectasis: Cutting a lung story short

  Smith, A. H. & Chalmers, J. D., 1 Jan 2020, In: Respirology . 25, 1, p. 43-44 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• Tiotropium/Olodaterol Delays Clinically Important Deterioration Compared with Tiotropium Monotherapy in Patients with Early COPD: a Post Hoc Analysis of the TONADO® Trials

  Rabe, K. F., Chalmers, J. D., Miravitlles, M., Kocks, J. W. H., Tsiligianni, I., de la Hoz, A., Xue, W., Singh, D., Ferguson, G. T. & Wedzicha, J., 11 Nov 2020, In: Advances in Therapy. 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • tiotropium-olodaterol
  • Tiotropium Bromide
  • Chronic Obstructive Pulmonary Disease
  • History
  • Maintenance
  5 Downloads (Pure)

• Updated guidance on the management of COVID-19: from an American Thoracic Society/European Respiratory Society coordinated International Task Force (29 July 2020)

  American Thoracic Society/European Respiratory Society Coordinated International Task Force, Bai, C., Chotirmall, S. H., Rello, J., Alba, G. A., Ginns, L. C., Krishnan, J. A., Rogers, R., Bendstrup, E., Burgel, P-R., Chalmers, J. D., Chua, A., Crothers, K. A., Duggal, A., Kim, Y. W., Laffey, J. G., Luna, C. M., Niederman, M. S., Raghu, G., Ramirez, J. A. & 38 others, Riera, J., Roca, O., Tamae-Kakazu, M., Torres, A., Watkins, R. R., Barrecheguren, M., Belliato, M., Chami, H. A., Chen, R., Cortes-Puentes, G. A., Delacruz, C., Hayes, M. M., Heunks, L. M. A., Holets, S. R., Hough, C. L., Jagpal, S., Jeon, K., Johkoh, T., Lee, M. M., Liebler, J., McElvaney, G. N., Moskowitz, A., Oeckler, R. A., Ojanguren, I., O'Regan, A., Pletz, M. W., Rhee, C. K., Schultz, M. J., Storti, E., Strange, C., Thomson, C. C., Torriani, F. J., Wang, X., Wuyts, W., Xu, T., Yang, D., Zhang, Z. & Wilson, K. C., 5 Oct 2020, In: European Respiratory Review. 29, 157, 15 p., 200287.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Coronavirus
  • Advisory Committees
  • Disease Management
  • Consensus
  • Thorax
  2 Citations (Scopus)

  6 Downloads (Pure)

• Using Airway Clearance Techniques in Bronchiectasis: Halfway There

  Spinou, A. & Chalmers, J. D., Oct 2020, In: Chest. 158, 4, p. 1298-1300 3 p.

  Research output: Contribution to journal › Editorial › peer-review

• Utility of routine screening for alpha-1 antitrypsin deficiency in patients with bronchiectasis

  Carreto, L., Morrison, M., Donovan, J., Finch, S., Tan, G. L., Fardon, T., Wilson, R., Furrie, E., Loebinger, M. & Chalmers, J. D., 26 Jun 2020, In: Thorax. 75, 7, p. 592-593 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • alpha 1-Antitrypsin Deficiency
  • Bronchiectasis
  • Guidelines
  • Thorax
  1 Citation (Scopus)

  28 Downloads (Pure)

• Validation of the Bronchiectasis Impact Measure (BIM) - a novel patient reported outcome measure

  Crichton, M. L., Dudgeon, E. K., Shoemark, A. & Chalmers, J. D., 19 Nov 2020, In: European Respiratory Journal.

  Research output: Contribution to journal › Article › peer-review

  • Bronchiectasis
  • Patient Reported Outcome Measures
  • Reproducibility of Results
  • Sputum
  • Cough

• Variability in airway inflammation, symptoms, lung function and reliever use in asthma: anti-inflammatory reliever hypothesis and STIFLE study design

  Harrison, T., Pavord, I. D., Chalmers, J. D., Whelan, G., Fagerås, M., Rutgersson, A., Belton, L., Siddiqui, S. & Gustafson, P., 8 Jun 2020, In: ERJ Open Research. 6, 2, p. 1-10 10 p., 00333.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pneumonia
  • Asthma
  • Anti-Inflammatory Agents
  • Formoterol Fumarate
  • Budesonide
  17 Downloads (Pure)

• Withdrawal of inhaled corticosteroids in COPD: A European Respiratory Society Guideline

  Chalmers, J. D., Laska, I. F., Franssen, F. M. E., Janssens, W., Pavord, I., Rigau, D., McDonnell, M. J., Roche, N., Sin, D. D., Stolz, D., Suissa, S., Wedzicha, J. & Miravitlles, M., 1 Jun 2020, In: European Respiratory Journal. 55, 6, 12 p., 2000351.

  Research output: Contribution to journal › Article › peer-review

  • Chronic Obstructive Pulmonary Disease
  • Adrenal Cortex Hormones
  • Guidelines
  • Bronchodilator Agents
  • Eosinophils
  13 Citations (Scopus)
• 2019

  A 2 × 2 factorial, randomised, open-label trial to determine the clinical and cost-effectiveness of hypertonic saline (HTS 6%) and carbocisteine for airway clearance versus usual care over 52 weeks in adults with bronchiectasis: a protocol for the CLEAR clinical trial

  Bradley, J. M., Anand, R., O'Neill, B., Ferguson, K., Clarke, M., Carroll, M., Chalmers, J., De Soyza, A., Duckers, J., Hill, A. T., Loebinger, M. R., Copeland, F., Gardner, E., Campbell, C., Agus, A., McGuire, A., Boyle, R., McKinney, F., Dickson, N., McAuley, D. F. & 1 others, Elborn, S., 19 Dec 2019, In: Trials. 20, 10 p., 747.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Clinical Trial Protocols
  • Bronchiectasis
  • Cost-Benefit Analysis
  • Sputum
  • Standard of Care
  45 Downloads (Pure)

• Airway Bacterial Load and Inhaled Antibiotic Response in Bronchiectasis

  Sibila, O., Laserna, E., Shoemark, A., Keir, H. R., Finch, S., Rodrigo-Troyano, A., Perea, L., Lonergan, M., Goeminne, P. C. & Chalmers, J. D., 1 Jul 2019, In: American Journal of Respiratory and Critical Care Medicine. 200, 1, p. 33-41 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Bronchiectasis
  • Bacterial Load
  • Anti-Bacterial Agents
  • Aztreonam
  • Quality of Life
  14 Citations (Scopus)

  27 Downloads (Pure)

• Antimicrobial peptides, disease severity and exacerbations in bronchiectasis

  Sibila, O., Perea, L., Cantó, E., Shoemark, A., Cassidy, D., Smith, A. H., Suarez-cuartin, G., Rodrigo-troyano, A., Keir, H. R., Oriano, M., Ong, S., Vidal, S., Blasi, F., Aliberti, S. & Chalmers, J. D., Sep 2019, In: Thorax. 74, 9, p. 835-842 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Secretory Leukocyte Peptidase Inhibitor
  • Bronchiectasis
  • Disease Progression
  • Peptides
  • Sputum
  3 Citations (Scopus)

  204 Downloads (Pure)

• A point of care neutrophil elastase activity assay identifies bronchiectasis severity, airway infection and risk of exacerbation

  Shoemark, A., Cant, E., Carreto, L., Smith, A., Oriano, M., Keir, H. R., Perea, L., Canto, E., Terranova, L., Vidal, S., Moffitt, K., Aliberti, S., Sibila, O. & Chalmers, J. D., 1 Jun 2019, In: European Respiratory Journal. 53, 6, 9 p., 1900303.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Leukocyte Elastase
  • Bronchiectasis
  • Point-of-Care Systems
  • Sputum
  • Infection
  11 Citations (Scopus)

  33 Downloads (Pure)