A bi-modal approach against cancer: Magnetic alginate nanoparticles for combined chemotherapy and hyperthermia

Gianni Ciofani; Cristina Riggio; Vittoria Raffa; Arianna Menciassi; Alfred Cuschieri

doi:10.1016/j.mehy.2009.01.031

A bi-modal approach against cancer: Magnetic alginate nanoparticles for combined chemotherapy and hyperthermia

Gianni Ciofani
, Cristina Riggio
, Vittoria Raffa
, Arianna Menciassi
, Alfred Cuschieri

Research output: Contribution to journal › Article › peer-review

71 Citations (Scopus)

Abstract

The use of polymeric carriers containing dispersed magnetic nanocrystailline particles has attracted considerable interest in the medical field. In this paper, We propose an innovative nanotechnological platform for cancer therapy, based on highly magnetized, biodegradable, and biocompatible polymeric nanoparticles. Alginate magnetic nanoparticles were prepared by our group by an efficient emulsion/reticulation technique and tested as drug delivery system. Here, we present a potential application that combines, in a single nanovector, efficient targeting, overcoming of bio-barriers, drug delivery, and physical disruption of tumor tissues. (C) 2009 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	80-82
Number of pages	3
Journal	Medical Hypotheses
Volume	73
Issue number	1
DOIs	https://doi.org/10.1016/j.mehy.2009.01.031
Publication status	Published - Jul 2009

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

MICROSPHERES

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10.1016/j.mehy.2009.01.031

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title = "A bi-modal approach against cancer: Magnetic alginate nanoparticles for combined chemotherapy and hyperthermia",

abstract = "The use of polymeric carriers containing dispersed magnetic nanocrystailline particles has attracted considerable interest in the medical field. In this paper, We propose an innovative nanotechnological platform for cancer therapy, based on highly magnetized, biodegradable, and biocompatible polymeric nanoparticles. Alginate magnetic nanoparticles were prepared by our group by an efficient emulsion/reticulation technique and tested as drug delivery system. Here, we present a potential application that combines, in a single nanovector, efficient targeting, overcoming of bio-barriers, drug delivery, and physical disruption of tumor tissues. (C) 2009 Elsevier Ltd. All rights reserved.",

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T2 - Magnetic alginate nanoparticles for combined chemotherapy and hyperthermia

AU - Ciofani, Gianni

AU - Riggio, Cristina

AU - Raffa, Vittoria

AU - Menciassi, Arianna

AU - Cuschieri, Alfred

PY - 2009/7

Y1 - 2009/7

N2 - The use of polymeric carriers containing dispersed magnetic nanocrystailline particles has attracted considerable interest in the medical field. In this paper, We propose an innovative nanotechnological platform for cancer therapy, based on highly magnetized, biodegradable, and biocompatible polymeric nanoparticles. Alginate magnetic nanoparticles were prepared by our group by an efficient emulsion/reticulation technique and tested as drug delivery system. Here, we present a potential application that combines, in a single nanovector, efficient targeting, overcoming of bio-barriers, drug delivery, and physical disruption of tumor tissues. (C) 2009 Elsevier Ltd. All rights reserved.

AB - The use of polymeric carriers containing dispersed magnetic nanocrystailline particles has attracted considerable interest in the medical field. In this paper, We propose an innovative nanotechnological platform for cancer therapy, based on highly magnetized, biodegradable, and biocompatible polymeric nanoparticles. Alginate magnetic nanoparticles were prepared by our group by an efficient emulsion/reticulation technique and tested as drug delivery system. Here, we present a potential application that combines, in a single nanovector, efficient targeting, overcoming of bio-barriers, drug delivery, and physical disruption of tumor tissues. (C) 2009 Elsevier Ltd. All rights reserved.

KW - MICROSPHERES

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JO - Medical Hypotheses

JF - Medical Hypotheses

IS - 1

ER -

A bi-modal approach against cancer: Magnetic alginate nanoparticles for combined chemotherapy and hyperthermia

Abstract

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