Background: Models incorporating long-term outcomes (LTOs) are not available to assess the health economic impact of attention-deficit/hyperactivity disorder (ADHD).
Objective: Develop a conceptual modelling framework capable of assessing long-term economic impact of ADHD therapies.
Methods: Literature was reviewed; a conceptual structure for the long-term model was outlined with attention to disease characteristics and potential impact of treatment strategies.
Results: The proposed model has four layers: i) multi-state short-term framework to differentiate between ADHD treatments; ii) multiple states being merged into three core health states associated with LTOs; iii) series of sub-models in which particular LTOs are depicted; iv) outcomes collected to be either used directly for economic analyses or translated into other relevant measures.
Conclusions: This conceptual model provides a framework to assess relationships between short- and long-term outcomes of the disease and its treatment, and to estimate the economic impact of ADHD treatments throughout the course of the disease.
|Number of pages||10|
|Journal||Expert Review of Pharmacoeconomics and Outcomes Research|
|Early online date||14 Dec 2016|
|Publication status||Published - 2017|
- Long-term model
- Conceptual model framework
- Long-term disease outcomes
- ADHD therapy