A Graph Cut Approach to Artery/Vein Classification in Ultra-Widefield Scanning Laser Ophthalmoscopy

Enrico Pellegrini (Lead / Corresponding author), Gavin Robertson, Tom MacGillivray, Jano van Hemert, John Houston, Emanuele Trucco

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Abstract

The classification of blood vessels into arterioles and venules is a fundamental step in the automatic investigation of retinal biomarkers for systemic diseases. In this paper we present a novel technique for vessel classification on ultra-wide-field-of-view images of the retinal fundus acquired with a scanning laser ophthalmoscope. To our best knowledge, this is the first time that a fully automated artery/vein classification technique for this type of retinal imaging with no manual intervention has been presented. The proposed method exploits hand-crafted features based on local vessel intensity and vascular morphology to formulate a graph representation from which a globally optimal separation between the arterial and venular networks is computed by graph cut approach. The technique was tested on three different datasets (one publicly available and two local) and achieved an average classification accuracy of 0.883 in the largest dataset.
Original languageEnglish
Article number8067510
Pages (from-to)516-526
Number of pages11
JournalIEEE Transactions on Medical Imaging
Volume37
Issue number2
Early online date13 Oct 2017
DOIs
Publication statusPublished - Feb 2018

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Keywords

  • artery-vein classification
  • blood vessel
  • graph cut
  • Retina
  • scanning laser ophthalmoscope
  • ultra-widefield

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