A mathematical model for endothelial cell migration during tumour-induced angiogenesis is presented. A possible explanation, in terms of desensitisation of cell-surface receptors, is given for the experimentally observed fact that without cell proliferation tumour vascularisation is never achieved.
- Endothelial cells
Anderson, A. R. A., & Chaplain, M. A. J. (1998). A mathematical model for capillary network formation in the absence of endothelial cell proliferation. Applied Mathematics Letters, 11(3), 109-114. https://doi.org/10.1016/S0893-9659(98)00041-X