A new role for Ran in ensuring precise duplication of chromosomal DNA

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    3 Citations (Scopus)

    Abstract

    To prevent re-replication of DNA, the licensing of replication origins is inhibited in S phase and G2. New work by Yamaguchi et al. (in this issue of Cell) shows that the small GTPase Ran can directly inhibit licensing inside nuclei once CDKs are active late in the cell cycle.
    Original languageEnglish
    Pages (from-to)2-4
    Number of pages3
    JournalCell
    Volume113
    Issue number1
    DOIs
    Publication statusPublished - 2003

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