Keyphrases
Aurora Kinase Inhibitor
100%
Spindle Assembly Checkpoint
100%
Pharmacodynamic Model
100%
Aurora B
100%
Kinetochore
100%
Anaphase
60%
Aurora Kinase A (AURKA)
60%
Aurora A
60%
Selective Inhibitor
60%
Chromosome Segregation
40%
Chemotherapy
40%
Microtubules
40%
Aneuploidy
40%
Phosphorylated Histone H3
40%
Biological Processes
20%
Tumor Progression
20%
Tumor
20%
Treatment Strategy
20%
Genomic Instability
20%
Kinetochore-microtubule Attachment
20%
Mitosis
20%
Cell Division
20%
Modeling Approach
20%
Cell Death
20%
Mechanistic Model
20%
BubR1
20%
Mad2
20%
Defining Characteristic
20%
Polyploidy
20%
Histone H3
20%
Specific Inhibitor
20%
Spindle Pole
20%
Sister Chromatids
20%
Drug Target
20%
Abrogation
20%
Mitotic Spindle Assembly
20%
Non-selective
20%
Loss of Control
20%
Synergistic Drug Combination
20%
Invasive Phenotype
20%
PKPD Modeling
20%
Quantitative Characterization
20%
Premature Mitosis
20%
Merotelic Attachments
20%
ZM447439
20%
Selective Treatment
20%
CDC20
20%
Target Molecule
20%
Metastatic Phenotype
20%
Experimental Validation
20%
Genetic Tumors
20%
Mitotic Defects
20%
Polyploid Cells
20%
Medicine and Dentistry
Spindle Checkpoint
100%
Pharmacodynamics
100%
Aurora Kinase Inhibitor
100%
Kinetochore
100%
Anaphase
60%
Histone H3
60%
Aurora A Kinase
60%
Aurora B Kinase
60%
Microtubule
40%
Aneuploidy
40%
Polyploidy
40%
Chromosome Segregation
40%
Chemotherapy
40%
Malignant Neoplasm
20%
Neoplasm
20%
Tumor Progression
20%
Cell Death
20%
Cell Division
20%
Phosphotransferase
20%
Prematurity
20%
Mitosis Spindle
20%
Combination Drug
20%
Biological Phenomena and Functions Concerning the Entire Organism
20%
Kinetochore Microtubule
20%
Sister Chromatid
20%
N [4 [6 Methoxy 7 (3 Morpholinopropoxy) 4 Quinazolinylamino]phenyl]benzamide
20%
Biological Marker
20%
Spindle Pole
20%
Biochemistry, Genetics and Molecular Biology
Spindle Checkpoint
100%
Kinetochore
100%
Aurora Kinase
100%
Pharmacodynamics
100%
Anaphase
50%
Aurora A Kinase
50%
Aurora B Kinase
50%
Histone H3
50%
Polyploid
33%
Chromosome Segregation
33%
Aneuploidy
33%
Biological Phenomena and Functions Concerning the Entire Organism
16%
Cell Division
16%
Tumor Progression
16%
Cell Death
16%
Genetics
16%
Phosphotransferase
16%
Kinase
16%
Mitosis Spindle
16%
Syntelic
16%
Sister Chromatid
16%