A placebo-controlled study examining the effect of allopurinol on heart rate variability and dysrhythmia counts in chronic heart failure

Abdullah M A  Shehab; Robert Butler; Robert J MacFadyen; Allan D Struthers

doi:10.1046/j.1365-2125.2001.01361.x

A placebo-controlled study examining the effect of allopurinol on heart rate variability and dysrhythmia counts in chronic heart failure

Abdullah M A Shehab
, Robert Butler
, Robert J MacFadyen
, Allan D Struthers

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Allopurinol improves endothelial function in chronic heart failure by reducing oxidative stress. We wished to explore if such an effect would attenuate autonomic dysfunction in CHF in line with many other effective therapies in CHF.

Original language	English
Pages (from-to)	329-334
Number of pages	6
Journal	British Journal of Clinical Pharmacology
Volume	51
Issue number	4
DOIs	https://doi.org/10.1046/j.1365-2125.2001.01361.x
Publication status	Published - 2001

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title = "A placebo-controlled study examining the effect of allopurinol on heart rate variability and dysrhythmia counts in chronic heart failure",

abstract = "Allopurinol improves endothelial function in chronic heart failure by reducing oxidative stress. We wished to explore if such an effect would attenuate autonomic dysfunction in CHF in line with many other effective therapies in CHF.",

author = "Shehab, \{Abdullah M A\} and Robert Butler and MacFadyen, \{Robert J\} and Struthers, \{Allan D\}",

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AU - MacFadyen, Robert J

AU - Struthers, Allan D

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N2 - Allopurinol improves endothelial function in chronic heart failure by reducing oxidative stress. We wished to explore if such an effect would attenuate autonomic dysfunction in CHF in line with many other effective therapies in CHF.

AB - Allopurinol improves endothelial function in chronic heart failure by reducing oxidative stress. We wished to explore if such an effect would attenuate autonomic dysfunction in CHF in line with many other effective therapies in CHF.

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DO - 10.1046/j.1365-2125.2001.01361.x

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JO - British Journal of Clinical Pharmacology

JF - British Journal of Clinical Pharmacology

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A placebo-controlled study examining the effect of allopurinol on heart rate variability and dysrhythmia counts in chronic heart failure

Abstract

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