A quantitative liposome microarray to systematically characterize protein-lipid interactions

Antoine Emmanuel Saliba, Ivana Vonkova, Stefano Ceschia, Greg M Findlay, Kenji Maeda, Christian Tischer, Samy Deghou, Vera van Noort, Peer Bork, Tony Pawson, Jan Ellenberg, Anne-Claude Gavin (Lead / Corresponding author)

Research output: Contribution to journalArticlepeer-review

67 Citations (Scopus)

Abstract

Lipids have a role in virtually all biological processes, acting as structural elements, scaffolds and signaling molecules, but they are still largely under-represented in known biological networks. Here we describe a liposome microarray-based assay (LiMA), a method that measures protein recruitment to membranes in a quantitative, automated, multiplexed and high-throughput manner.

Original languageEnglish
Pages (from-to)47-50
Number of pages4
JournalNature Methods
Volume11
Issue number1
Early online date24 Nov 2013
DOIs
Publication statusPublished - Jan 2014

ASJC Scopus subject areas

  • Biotechnology
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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