A randomized clinical trial of the effectiveness of 0.018-inch and 0.022-inch slot orthodontic bracket systems: part 3 - biological side-effects of treatment

TY - JOUR

T1 - A randomized clinical trial of the effectiveness of 0.018-inch and 0.022-inch slot orthodontic bracket systems

T2 - part 3 - biological side-effects of treatment

AU - El-Angbawi, Ahmed M.

AU - Yassir, Yassir A.

AU - McIntyre, Grant T.

AU - Revie, Gavin F.

AU - Bearn, David R.

PY - 2019/4

Y1 - 2019/4

N2 - Objective: To compare orthodontically induced inflammatory root resoprtion (OIIRR) and patient perception of pain during orthodontic treatment between 0.018-inch and 0.022-inch slot bracket systems. Subjects and methods: Eligible participants aged 12 years or over were allocated to treatment with the 0.018-inch or 0.022-inch slot MBT appliance (3M-Unitek, Monrovia, California) using block randomisation in groups of ten. OIIRR was assessed radiographically using standardised periapical radiographs before and after 9 months from the start of treatment. Patient perception of pain was assessed using a validated patient questionnaire at 6 months from the start of treatment. Parametric tests (t-test) and non-parametric tests (Chi-square with Fisher’s exact tests and Kruskal-Wallis test) assessed differences between the groups (P < 0.05). The correlation between severity of OIIRR and abnormal root morphology, history of dental trauma, and pain during treatment was assessed. Results: Of the 187 participants randomised (1:1 ratio), 34 withdrew or were excluded (protocol deviations or poor cooperation). There were 77 patients in the 0.018-inch slot group and 76 patients in the 0.022-inch slot group (overall mean age: 19.1 years). Baseline characteristics were similar between groups (P > 0.05). There was no significant difference in the severity of the OIIRR nor patient perception of pain between the two study groups (P=0.115 and P= 0.08 respectively). The correlation between the severity of OIIRR and abnormal root morphology or history of dental trauma was not statistically significant (P=0.086 and P=0.313). Moreover, there was no significant correlation between the severity of OIIRR and pain during treatment (R= 0.045, P=0.617). Limitations: It was impossible to blind clinicians or patients to allocation and oral hygiene and periodontal outcomes were not assessed. Conclusions: The effect of bracket slot size on the on the severity of OIIRR and patient perception of pain is not significant.

AB - Objective: To compare orthodontically induced inflammatory root resoprtion (OIIRR) and patient perception of pain during orthodontic treatment between 0.018-inch and 0.022-inch slot bracket systems. Subjects and methods: Eligible participants aged 12 years or over were allocated to treatment with the 0.018-inch or 0.022-inch slot MBT appliance (3M-Unitek, Monrovia, California) using block randomisation in groups of ten. OIIRR was assessed radiographically using standardised periapical radiographs before and after 9 months from the start of treatment. Patient perception of pain was assessed using a validated patient questionnaire at 6 months from the start of treatment. Parametric tests (t-test) and non-parametric tests (Chi-square with Fisher’s exact tests and Kruskal-Wallis test) assessed differences between the groups (P < 0.05). The correlation between severity of OIIRR and abnormal root morphology, history of dental trauma, and pain during treatment was assessed. Results: Of the 187 participants randomised (1:1 ratio), 34 withdrew or were excluded (protocol deviations or poor cooperation). There were 77 patients in the 0.018-inch slot group and 76 patients in the 0.022-inch slot group (overall mean age: 19.1 years). Baseline characteristics were similar between groups (P > 0.05). There was no significant difference in the severity of the OIIRR nor patient perception of pain between the two study groups (P=0.115 and P= 0.08 respectively). The correlation between the severity of OIIRR and abnormal root morphology or history of dental trauma was not statistically significant (P=0.086 and P=0.313). Moreover, there was no significant correlation between the severity of OIIRR and pain during treatment (R= 0.045, P=0.617). Limitations: It was impossible to blind clinicians or patients to allocation and oral hygiene and periodontal outcomes were not assessed. Conclusions: The effect of bracket slot size on the on the severity of OIIRR and patient perception of pain is not significant.

KW - Adolescent

KW - Adult

KW - Child

KW - Female

KW - Humans

KW - Male

KW - Malocclusion/therapy

KW - Orthodontic Appliance Design

KW - Orthodontic Brackets/adverse effects

KW - Orthodontics, Corrective/adverse effects

KW - Pain Measurement/methods

KW - Pain Perception

KW - Patient Reported Outcome Measures

KW - Radiography, Dental

KW - Root Resorption/diagnostic imaging

KW - Severity of Illness Index

KW - Treatment Outcome

KW - Young Adult

U2 - 10.1093/ejo/cjy039

DO - 10.1093/ejo/cjy039

M3 - Article

C2 - 30007330

SN - 0141-5387

VL - 41

SP - 154

EP - 164

JO - European Journal of Orthodontics

JF - European Journal of Orthodontics

IS - 2

M1 - cjy039

ER -